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Journal Articles

Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis

Yun Cui, Yongxia Chang, Xixi Ma, Meng Sun, Yuliang Huang, Feng Yang, Shuang Li, Wei Zhuo, Wei Liu, Bo Yang, Aifu Lin, Guangshuo Ou, Yuehong Yang, Shanshan Xie, Tianhua Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (2): 263–276.
https://doi.org/10.1158/0008-5472.CAN-24-1254
Published: 15 January 2025
View articletitled, Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis
Open the PDF for Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract CT098: Phase I study of GQ1005, a new generation HER2-ADC, in patients with HER2-expressing and HER2 mutated advanced solid tumors

Caicun Zhou, Bo Yang, Ting Deng, Biyun Wang, Jian Zhang, Yuping Sun, Linlin Wang, Hongwei Yang, Jingfen Wang, Wei Li, Qi Song, Yuchong Yang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT098.
https://doi.org/10.1158/1538-7445.AM2024-CT098
Published: 05 April 2024
View articletitled, Abstract CT098: Phase I study of GQ1005, a new generation HER2-ADC, in patients with HER2-expressing and HER2 mutated advanced solid tumors
Journal Articles

Abstract 2702: GQ1001 is a next generation HER2-targeting ADC with excellent druggability, safety and potency

Lei Huang, Lili Shi, Yajun Sun, Cao Lv, Chengcheng Gong, Chong Liu, Jun Yang, Lu Jiang, Jinduo Yuan, Xuesong Li, Mingyu Hu, Xinju Gao, Yu Si, Hui Yang, Yan Shi, Bo Yang, Paul H. Song, Gang Qin, Biyun Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2702.
https://doi.org/10.1158/1538-7445.AM2023-2702
Published: 04 April 2023
View articletitled, Abstract 2702: GQ1001 is a next generation HER2-targeting ADC with excellent druggability, safety and potency
Journal Articles

Abstract CT544: Multi-omics analysis uncovers prognostic biomarkers and tumor ecosystem dynamics during toripalimab combined with nab-paclitaxel and s-1 as neoadjuvant therapy for esophageal squamous carcinoma: A single-center, open-label, single-arm phase 2 trial

Guoqing Zhang, Jing Yuan, Chaohu Pan, Qing Xu, Xiaoli Cui, Jing Zhang, Minglu Liu, Zhigang Song, Liangliang Wu, Dongfang Wu, Bo Yang, Haitao Luo, Yi Hu, Shunchang Jiao
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT544.
https://doi.org/10.1158/1538-7445.AM2022-CT544
Published: 15 June 2022
View articletitled, Abstract CT544: Multi-omics analysis uncovers prognostic biomarkers and tumor ecosystem dynamics during toripalimab combined with nab-paclitaxel and s-1 as neoadjuvant therapy for esophageal squamous carcinoma: A single-center, open-label, single-arm phase 2 trial
Journal Articles

Abstract 789: Development and validation of a capture based NGS assay that enables the detection of Epstein Barr virus from gastric cancer patients' tumor tissues

Yajie Hu, Bo Yang, Lei Wang, Shiyi Liu, Lei Liang, Jie Wang, Fugen Li, Yu Sun
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 789.
https://doi.org/10.1158/1538-7445.AM2020-789
Published: 15 August 2020
View articletitled, Abstract 789: Development and validation of a capture based NGS assay that enables the detection of Epstein Barr virus from gastric cancer patients' tumor tissues
Journal Articles

Abstract 5477: A novel loci-selected method for microsatellite instability detection validated on a large Chinese cohort

Jian Li, Zhenghang Wang, Bo Yang, Bin Li, Yunjie Song, Bei Zhang, Xiaochen Zhao, Yifan Zhou, Zhenghua Xie, Xiaofang Li, Hao Chen, Hua Dong, Yuezong Bai, Lei Xiong, Fugen Li, Jing Gao, Lin Shen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5477.
https://doi.org/10.1158/1538-7445.AM2020-5477
Published: 15 August 2020
View articletitled, Abstract 5477: A novel loci-selected method for microsatellite instability detection validated on a large Chinese cohort
Journal Articles

Abstract 4289: Detection of germline large genomic rearrangements in BRCA1/2 genes by a capture-based NGS panel reveals its contribution to Chinese patients with solid tumors

Jing Li, Bo Yang, Kefei Huang, Changhao Liu, Hua Dong, Jie Wang, Fugen Li, Zhong-qiu Lin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4289.
https://doi.org/10.1158/1538-7445.AM2020-4289
Published: 15 August 2020
View articletitled, Abstract 4289: Detection of germline large genomic rearrangements in BRCA1/2 genes by a capture-based NGS panel reveals its contribution to Chinese patients with solid tumors
Journal Articles

USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ

Hong Zhu, Fangjie Yan, Tao Yuan, Meijia Qian, Tianyi Zhou, Xiaoyang Dai, Ji Cao, Meidan Ying, Xiaowu Dong, Qiaojun He, Bo Yang
Journal: Cancer Research
Cancer Res (2020) 80 (11): 2204–2216.
https://doi.org/10.1158/0008-5472.CAN-19-2388
Published: 02 June 2020
View articletitled, USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ
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Includes: Supplementary data
Journal Articles

Correction: Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells

Ji Cao, Yijie Wang, Rong Dong, Guanyu Lin, Ning Zhang, Jing Wang, Nengming Lin, Yongchuan Gu, Ling Ding, Meidan Ying, Qiaojun He, Bo Yang
Journal: Cancer Research
Cancer Res (2020) 80 (11): 2421.
https://doi.org/10.1158/0008-5472.CAN-20-1147
Published: 02 June 2020
View articletitled, Correction: Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
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Journal Articles

Aurora A Inhibition Eliminates Myeloid Cell–Mediated Immunosuppression and Enhances the Efficacy of Anti–PD-L1 Therapy in Breast Cancer

Tingting Yin, Zhi-Bin Zhao, Jing Guo, Tianchen Wang, Jing-Bo Yang, Chao Wang, Jie Long, Shisong Ma, Qiang Huang, Kaiguang Zhang, Xiaopeng Ma, Chenhai Liu, Suling Liu, Zhe-Xiong Lian, Zhenye Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13): 3431–3444.
https://doi.org/10.1158/0008-5472.CAN-18-3397
Published: 01 July 2019
View articletitled, Aurora A Inhibition Eliminates Myeloid Cell–Mediated Immunosuppression and Enhances the Efficacy of Anti–PD-L1 Therapy in Breast Cancer
Open the PDF for Aurora A Inhibition Eliminates Myeloid Cell–Mediated Immunosuppression and Enhances the Efficacy of Anti–PD-L1 Therapy in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression

Jian-Ping He, Pei-Pei Hou, Qi-Tao Chen, Wei-Jia Wang, Xiao-Yu Sun, Peng-Bo Yang, Ying-Ping Li, Lu-Ming Yao, Xiaotong Li, Xin-Dong Jiang, Kun-Yi Chien, Zhi-Ming Zhang, Qiu-Wan Wu, Allison J. Cowin, Qiao Wu, Hang-Zi Chen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (17): 4853–4864.
https://doi.org/10.1158/0008-5472.CAN-17-3835
Published: 04 September 2018
View articletitled, Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
Open the PDF for Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R–YAP Axis

Hong Zhu, Dan-Dan Wang, Tao Yuan, Fang-Jie Yan, Chen-Ming Zeng, Xiao-Yang Dai, Zi-bo Chen, Ying Chen, Tianyi Zhou, Guang-Han Fan, Meidan Ying, Ji Cao, Peihua Luo, Xi-Jie Liu, Yuandong Hu, Yong Peng, Qiaojun He, Bo Yang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (14): 3995–4006.
https://doi.org/10.1158/0008-5472.CAN-17-1548
Published: 15 July 2018
View articletitled, Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R–YAP Axis
Open the PDF for Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R–YAP Axis in another window
Includes: Supplementary data
Journal Articles

Abstract 515: Integrative analysis of LncRNA-drug interactions in cancer identified EPIC1 as an oncogenic lncRNA that regulates breast cancer tumorigenesis and iBET resistance through regulating MYC transcriptional activity

Yue Wang, Zehua Wang, Bo Yang, Min Zhang, Da Yang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 515.
https://doi.org/10.1158/1538-7445.AM2018-515
Published: 01 July 2018
View articletitled, Abstract 515: Integrative analysis of LncRNA-drug interactions in cancer identified EPIC1 as an oncogenic lncRNA that regulates breast cancer tumorigenesis and iBET resistance through regulating MYC transcriptional activity
Journal Articles

Abstract 2070: HMGB1 governs p53 to autophagic degradation via its nucleus-to-cytoplasm transport

Qiaojun He, Peihua Luo, Xiaochun Yang, Qinjie Weng, Ling Ding, Bo Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2070.
https://doi.org/10.1158/1538-7445.AM2017-2070
Published: 01 July 2017
View articletitled, Abstract 2070: HMGB1 governs p53 to autophagic degradation via its nucleus-to-cytoplasm transport
Journal Articles

Abstract 3495: The DNA methylation landscape of long noncoding RNAs in human cancer

Da Yang, Zehua Wang, Bo Yang, Min Zhang, Zhiyuan Wu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3495.
https://doi.org/10.1158/1538-7445.AM2017-3495
Published: 01 July 2017
View articletitled, Abstract 3495: The DNA methylation landscape of long noncoding RNAs in human cancer
Journal Articles

Abstract 1638: Hypoxia-induced WSB1 promotes the metastatic potential of osteosarcoma cells

Yijie Wang, Ji Cao, Rong Dong, Guanyu Lin, Zibo Chen, Ling Ding, Meidan Ying, Qiaojun He, Bo Yang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1638.
https://doi.org/10.1158/1538-7445.AM2016-1638
Published: 15 July 2016
View articletitled, Abstract 1638: Hypoxia-induced WSB1 promotes the metastatic potential of osteosarcoma cells
Journal Articles

Abstract 5079: Sunitinib suppresses ovarian cancer metastasis through the negative modulation of TGF-β-mediated epithelial-mesenchymal transition

Zibo Chen, Lin-lin Chang, Tian-yi Zhou, Dan-dan Wang, Ying Chen, Hong Zhu, Meidan Ying, Bo Yang, Qiao-jun He
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5079.
https://doi.org/10.1158/1538-7445.AM2016-5079
Published: 15 July 2016
View articletitled, Abstract 5079: Sunitinib suppresses ovarian cancer metastasis through the negative modulation of TGF-β-mediated epithelial-mesenchymal transition
Journal Articles

Abstract 1142: E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma by promoting ubiquitination-mediated degradation of RARa

Qian Zhou, Meidan Ying, Bo Yang, Qiaojun He
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1142.
https://doi.org/10.1158/1538-7445.AM2016-1142
Published: 15 July 2016
View articletitled, Abstract 1142: E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma by promoting ubiquitination-mediated degradation of RARa
Journal Articles

Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells

Ji Cao, Yijie Wang, Rong Dong, Guanyu Lin, Ning Zhang, Jing Wang, Nengming Lin, Yongchuan Gu, Ling Ding, Meidan Ying, Qiaojun He, Bo Yang
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4839–4851.
https://doi.org/10.1158/0008-5472.CAN-15-0711
Published: 15 November 2015
View articletitled, Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Open the PDF for Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 1434: MDM2 promotes tumor cell migration through the induction of epithelial to mesenchymal transition

Lin Zheng, Yeping Wu, Tianyi Zhou, Hong Zhu, Qiaojun He, Bo Yang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1434.
https://doi.org/10.1158/1538-7445.AM2015-1434
Published: 01 August 2015
View articletitled, Abstract 1434: MDM2 promotes tumor cell migration through the induction of epithelial to mesenchymal transition