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Journal Articles

Abstract 2721: Mechanism Studies of HDACi combined with SP/KLF inhibitors in the treatment of H3K27M-mutant diffuse intrinsic pontine gliomas

Bo Wang, Yu Kong, Xuejiao Lv, Hao Zhuang, Xudong Wu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2721.
https://doi.org/10.1158/1538-7445.AM2025-2721
Published: 21 April 2025
View articletitled, Abstract 2721: Mechanism Studies of HDACi combined with SP/KLF inhibitors in the treatment of H3K27M-mutant diffuse intrinsic pontine gliomas
Journal Articles

Abstract 685: Integrative screening of DNA methylation markers enables early detection of hepatocellular carcinoma

Hao Zhuang, Bo Wang, Yongmei Li
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 685.
https://doi.org/10.1158/1538-7445.AM2025-685
Published: 21 April 2025
View articletitled, Abstract 685: Integrative screening of DNA methylation markers enables early detection of hepatocellular carcinoma
Journal Articles

Abstract A029: Evaluating and interpreting scGPT: A foundation model for single-cell biology in real-world cancer clinical trial data

Runzi Tan, Haotian Cui, Bo Wang, Kimberly Perez, Andressa Dias Costa, Alexander Jordan, Thomas Karacic, Dalia Elganainy, Dan Y Gui, Suryun Kim, Chen Yuan, Morgan Truitt, Michael Downes, Ronald Evans, Tae Gyu Oh, Peter O’Dwyer, Andrew Aguirre, Jonathan A Nowak, Brian Wolpin, Simona Cristea
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A029.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A029
Published: 15 September 2024
View articletitled, Abstract A029: Evaluating and interpreting scGPT: A foundation model for single-cell biology in real-world cancer clinical trial data
Journal Articles

Abstract 7567: In-depth mass cytometry analysis reveals different immune cell composition of unique molecular subtypes in extensive stage small-cell lung cancer

Yuekang Li, Jingjing Qu, Binggen Wu, Qian Shen, Wenjia Sun, Lijun Chen, Bo Wang, Lixiong Ying, Jianya Zhou, Jianying Zhou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7567.
https://doi.org/10.1158/1538-7445.AM2024-7567
Published: 22 March 2024
View articletitled, Abstract 7567: In-depth mass cytometry analysis reveals different immune cell composition of unique molecular subtypes in extensive stage small-cell lung cancer
Journal Articles

Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes

Sarmila Majumder, Satavisha Roy, Thomas Kaffenberger, Bo Wang, Stefan Costinean, Wendy Frankel, Anna Bratasz, Periannan Kuppusamy, Tsonwin Hai, Kalpana Ghoshal, Samson T. Jacob
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4179.
https://doi.org/10.1158/0008-5472.CAN-23-2367
Published: 15 December 2023
View articletitled, Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes
Open the PDF for Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes in another window
Journal Articles

Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis

Jharna Datta, Huban Kutay, Mohd W. Nasser, Gerard J. Nuovo, Bo Wang, Sarmila Majumder, Chang-Gong Liu, Stefano Volinia, Carlo M. Croce, Thomas D. Schmittgen, Kalpana Ghoshal, Samson T. Jacob
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4181.
https://doi.org/10.1158/0008-5472.CAN-23-2365
Published: 15 December 2023
View articletitled, Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis
Open the PDF for Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis in another window
Journal Articles

Abstract 3842: Berberine recognition of the dGMP-bound PDGFR-β promoter G-quadruplex: Structural insight into specific drug targeting

Kai-Bo Wang, Jonathan Dickerhoff, Yichen Han, Danzhou Yang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3842.
https://doi.org/10.1158/1538-7445.AM2023-3842
Published: 04 April 2023
View articletitled, Abstract 3842: Berberine recognition of the dGMP-bound PDGFR-β promoter G-quadruplex: Structural insight into specific drug targeting
Journal Articles

Abstract 3103: Dual targeting MYC G-quadruplex and topoisomerase I by indenoisoquinolines for cancer therapy

Danzhou Yang, Mark Cushman, Kai-Bo Wang, Mohamed S. Elsayed, Guanhui Wu, Adam J. Buric, Mercedes DeMoss
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3103.
https://doi.org/10.1158/1538-7445.AM2023-3103
Published: 04 April 2023
View articletitled, Abstract 3103: Dual targeting MYC G-quadruplex and topoisomerase I by indenoisoquinolines for cancer therapy
Journal Articles

HDAC5 Loss Enhances Phospholipid-Derived Arachidonic Acid Generation and Confers Sensitivity to cPLA2 Inhibition in Pancreatic Cancer

Penglin Pan, Gengdu Qin, Bo Wang, Haixin Yu, Jie Chen, Jiaying Liu, Kaijian Bing, Jian Shen, Dianyun Ren, Yuhan Zhao, Wentao Xia, Hui Li, Heshui Wu, Yingke Zhou
Journal: Cancer Research
Cancer Res (2022) 82 (24): 4542–4554.
https://doi.org/10.1158/0008-5472.CAN-21-4362
Published: 16 December 2022
View articletitled, HDAC5 Loss Enhances Phospholipid-Derived Arachidonic Acid Generation and Confers Sensitivity to cPLA2 Inhibition in Pancreatic Cancer
Open the PDF for HDAC5 Loss Enhances Phospholipid-Derived Arachidonic Acid Generation and Confers Sensitivity to cPLA2 Inhibition in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4106: Curating protein complexes from multiple resources and validate their co-regulations at RNA/protein level in pan-cancer

Yizhe Song, Daniel Cui Zhou, Yize Li, Liang-Bo Wang, Michael C. Wendl, Gad Getz, Li Ding
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4106.
https://doi.org/10.1158/1538-7445.AM2022-4106
Published: 15 June 2022
View articletitled, Abstract 4106: Curating protein complexes from multiple resources and validate their co-regulations at RNA/protein level in pan-cancer
Journal Articles

Abstract 1932: Pollock: Fishing for cell states

Erik Storrs, Daniel Cui Zhou, Michael C. Wendl, Matthew A. Wyczalkowski, Alla Karpova, Liang-Bo Wang, Yize Li, Austin Southard-Smith, Reyka G. Jayasinghe, Lijun Yao, Ruiyang Liu, Yige Wu, Nadezhda V. Terekhanova, Houxiang Zhu, John M. Herndon, Feng Chen, William E. Gillanders, Ryan C. Fields, Li Ding
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1932.
https://doi.org/10.1158/1538-7445.AM2022-1932
Published: 15 June 2022
View articletitled, Abstract 1932: Pollock: Fishing for cell states
Journal Articles

Abstract 5027: PTMcosmos: A web portal of post-translational modifications and proteogenomic resources in cancer

Liang-Bo Wang, Akshay Govindan, Song Cao, Li Ding
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5027.
https://doi.org/10.1158/1538-7445.AM2022-5027
Published: 15 June 2022
View articletitled, Abstract 5027: PTMcosmos: A web portal of post-translational modifications and proteogenomic resources in cancer
Journal Articles

Abstract 1087: Development and characterization of a bispecific antibody (GB265) against PD-L1 and TIGIT

Su Huang, Riyao Yang, Cai Huang, Saroja Putrevu, Nathan S. Fay, Kimberly Wright, Mohd Saif Zaman, Betty Huang, Bo Wang, Meredith Wright, Yanan Wang, Xuefei Tian, Yue Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1087.
https://doi.org/10.1158/1538-7445.AM2022-1087
Published: 15 June 2022
View articletitled, Abstract 1087: Development and characterization of a bispecific antibody (GB265) against PD-L1 and TIGIT
Journal Articles

Abstract 2832: Identifying tumor specific surface protein markers for glioblastoma immunotherapy by single-nuclei RNA-seq

Omar M. Ibrahim, Liang-Bo Wang, Lijun Yao, Wagma Caravan, Nataly Naser Al Deen, Reyka G. Jayasinghe, Milan G. Chheda, Li Ding
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2832.
https://doi.org/10.1158/1538-7445.AM2022-2832
Published: 15 June 2022
View articletitled, Abstract 2832: Identifying tumor specific surface protein markers for glioblastoma immunotherapy by single-nuclei RNA-seq
Journal Articles

Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis

Yang Cheng, Fuxiang Bai, Xiaolei Ren, Renhui Sun, Xiaowei Guo, Wen Liu, Bo Wang, Yongheng Yang, Xiaolu Zhang, Yong Xu, Chunyang Li, Xiaoyun Yang, Lifen Gao, Chunhong Ma, Xueen Li, Xiaohong Liang
Journal: Cancer Research
Cancer Res (2022) 82 (8): 1603–1616.
https://doi.org/10.1158/0008-5472.CAN-21-0003
Published: 15 April 2022
View articletitled, Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis
Open the PDF for Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis in another window
Includes: Supplementary data
Journal Articles

Abstract 2170: Proteogenomic and metabolomic characterization of human glioblastoma

Liang-Bo Wang, Alla Karpova, Marina A. Gritsenko, Jennifer E. Kyle, Song Cao, Yize Li, Dmitry Rykunov, Antonio Colaprico, Joseph Rothstein, Runyu Hong, Vasileios Stathias, MacIntosh Cornwell, Francesca Petralia, Richard D. Smith, Antonio Iavarone, Milan G. Chheda, Jill S. Barnholtz-Sloan, Karin D. Rodland, Tao Liu, Li Ding, Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2170.
https://doi.org/10.1158/1538-7445.AM2021-2170
Published: 01 July 2021
View articletitled, Abstract 2170: Proteogenomic and metabolomic characterization of human glioblastoma
Journal Articles

Abstract LB068: A novel CD20/CD3 T cell engager designed from Rituximab targeting CD20+ cancer with multiple mechanisms

Wenyan Cai, Jianbo Dong, Sachith Gallolu Kankanamalage, Allison Titong, Jiadong Shi, Zhejun Jia, Bo Wang, Cai Huang, Jing Zhang, Jun Lin, Steven Z. Kan, Joe Zhou, Yue Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB068.
https://doi.org/10.1158/1538-7445.AM2021-LB068
Published: 01 July 2021
View articletitled, Abstract LB068: A novel CD20/CD3 T cell engager designed from Rituximab targeting CD20+ cancer with multiple mechanisms
Journal Articles

Abstract LB067: Development of a novel bispecific antibody targeting PD-L1 and CD55 for cancer therapy

Amit K. Chaudhary, Jiadong Shi, Wenyan Cai, Bo Wang, Mohd S. Zaman, Cai Huang, Jun Lin, Steven Z. Kan, Joe Zhou, Jianbo Dong, Yue Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB067.
https://doi.org/10.1158/1538-7445.AM2021-LB067
Published: 01 July 2021
View articletitled, Abstract LB067: Development of a novel bispecific antibody targeting PD-L1 and CD55 for cancer therapy
Journal Articles

Abstract 2983: A synthetic derivative of 1,2,3-triazole-pyrimidine hybrid reverses multidrug resistance mediated by MRP7

Jing-Quan Wang, Zi-Ning Lei, Qiu-Xu Teng, Bo Wang, Li-Ying Ma, Hong-Min Liu, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2983.
https://doi.org/10.1158/1538-7445.AM2020-2983
Published: 15 August 2020
View articletitled, Abstract 2983: A synthetic derivative of 1,2,3-triazole-pyrimidine hybrid reverses multidrug resistance mediated by MRP7
Journal Articles

Abstract 2776: MEDI5752: A novel bispecific antibody that preferentially targets CTLA-4 on PD-1 expressing T-cells

Simon J. Dovedi, Yariv Mazor, Matthew Elder, Sumati Hasani, Bo Wang, Suzanne Mosely, Desmond Jones, Anna Hansen, Chuning Yang, Yanli Wu, Ikbel Achour, Nick Durham, Gareth Browne, Thomas Murray, James Hair, Michelle Morrow, Godfrey Rainey, Maria Jure Kunkel, John Gooya, Daniel Freeman, Ronald Herbst, Robert Wilkinson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2776.
https://doi.org/10.1158/1538-7445.AM2018-2776
Published: 01 July 2018
View articletitled, Abstract 2776: MEDI5752: A novel bispecific antibody that preferentially targets CTLA-4 on PD-1 expressing T-cells