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Journal Articles

Abstract 3059: Targeting tumor progression: The impact of SMR peptide and miRNA on exosome-inflammasome-EMT axis in breast cancer

Free
Ming Bo Huang, Erica L. Johnson, Lily Yang, Jonathan Stiles, Aykut Uren, Fengxia Yan, Vincent C. Bond
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3059.
https://doi.org/10.1158/1538-7445.AM2025-3059
Published: 21 April 2025
View articletitled, Abstract 3059: Targeting tumor progression: The impact of SMR peptide and miRNA on exosome-inflammasome-EMT axis in breast cancer
Journal Articles

Abstract 4798: In vivo generation of universal CAR T cells for targeting heterologous antigens in solid tumors

Free
Suilan Zheng, Bo Huang, Sudarshan R. Kasireddy, Yashapal Singh, Haiyan Chu, Madduri Srinivasarao, Laurie Beitz, Byoung Ryu, Andrew Scharenberg, Philip Low
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4798.
https://doi.org/10.1158/1538-7445.AM2025-4798
Published: 21 April 2025
View articletitled, Abstract 4798: In vivo generation of universal CAR T cells for targeting heterologous antigens in solid tumors
Journal Articles

Abstract 4505: Discovery of a cebrelon-based PTPN1/PTPN2 dual targeting degrader for cancer immunotherapy

Free
Zihan Qu, Yunpeng Bai, Jiajun Dong, Zheng Zhang, Bo Huang, Yiming Miao, Andy W. Tao, Philip S. Low, Zhong-Yin Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4505.
https://doi.org/10.1158/1538-7445.AM2024-4505
Published: 22 March 2024
View articletitled, Abstract 4505: Discovery of a cebrelon-based PTPN1/PTPN2 dual targeting degrader for cancer immunotherapy
Journal Articles

Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator

Free
Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Siyu Feng, Martin Sjöström, Raunak Shrestha, Meng Zhang, Lisa N. Chesner, Hyun Jin Shin, Marsha Calvert, Jonathan Chou, Rajdeep Das, Emily A. Egusa, Aidan Winters, Jun Zhu, Ashutosh Maheshwari, Junjie T. Hua, Mohammed Alshalalfa, William S. Chen, Bradley A. Stohr, Javed Siddiqui, Bo Huang, Eric J. Small, David A. Quigley, Kevan M. Shokat, Luke A. Gilbert, Felix Y. Feng
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B066.
https://doi.org/10.1158/1538-7445.PRCA2023-B066
Published: 02 June 2023
View articletitled, Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator
Journal Articles

Abstract 4099: Dual targeting of tumor cells and cancer associated fibroblasts enhances CAR T efficacy in solid tumors

Free
Bo Huang, Suilan Zheng, Haiyan Chu, Ramesh Mukkamala, Suresh K. Bowroju, Yashapal Singh, Sudarsan R. Kasireddy, Md Sazzadul Bari, Madduri Srinivasarao, Laurie Beitz, Byoung Ryu, Michael Jensen, Andrew M. Scharenberg, Philip S. Low
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4099.
https://doi.org/10.1158/1538-7445.AM2023-4099
Published: 04 April 2023
View articletitled, Abstract 4099: Dual targeting of tumor cells and cancer associated fibroblasts enhances CAR T efficacy in solid tumors
Journal Articles

Abstract 1787: Design of bispecific adapters for universal CAR T cell therapies of solid tumors

Free
Suilan Zheng, Bo Huang, Yashapal Singh, Haiyan Chu, Suresh K. Bowroju, Md Sazzadul Bari, Madduri Srinivasarao, Sudarsan R. Kasireddy, Ramesh Mukkamala, Laurie Beitz, Byoung Ryu, Andrew M. Scharenberg, Michael Jensen, Philip S. Low
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1787.
https://doi.org/10.1158/1538-7445.AM2023-1787
Published: 04 April 2023
View articletitled, Abstract 1787: Design of bispecific adapters for universal CAR T cell therapies of solid tumors
Journal Articles

Abstract 4: Intercepting ribosomal protein S6KB1 signaling: Prevention of prostate cancer recurrence

Free
Addanki Pratap Kumar, Alison Clark, Michelle Villarreal, Sridharan Jayamohan, Shih-Bo Huang, Suleman S. Hussain, Xiaoyu Yang, Paul Rivas, Darpan Patel, Bethany L. Pierce, Shreya Tripathy, Pawel Osmulski, Maria Gaczynska, Lai Zhao, Li-Ju Wang, Yidong Chen, Caroline Xavier Paul Ezhilan, Mohan Natarajan, Joel E. Michalek, Robert L. Reddick, Rita Ghosh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4.
https://doi.org/10.1158/1538-7445.AM2022-4
Published: 15 June 2022
View articletitled, Abstract 4: Intercepting ribosomal protein S6KB1 signaling: Prevention of prostate cancer recurrence
Journal Articles

Hypoxia Promotes Breast Cancer Cell Growth by Activating a Glycogen Metabolic Program

Available to Purchase
Ke Tang, Liyan Zhu, Jie Chen, Dianheng Wang, Liping Zeng, Chen Chen, Liang Tang, Li Zhou, Keke Wei, Yabo Zhou, Jiadi Lv, Yuying Liu, Huafeng Zhang, Jingwei Ma, Bo Huang
Journal: Cancer Research
Cancer Res (2021) 81 (19): 4949–4963.
https://doi.org/10.1158/0008-5472.CAN-21-0753
Published: 01 October 2021
View articletitled, Hypoxia Promotes Breast Cancer Cell Growth by Activating a Glycogen Metabolic Program
Open the PDF for Hypoxia Promotes Breast Cancer Cell Growth by Activating a Glycogen Metabolic Program in another window
Includes: Supplementary data
Journal Articles

Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells

Free
Yuying Liu, Tianzhen Zhang, Haizeng Zhang, Jiping Li, Nannan Zhou, Roland Fiskesund, Junwei Chen, Jiadi Lv, Jingwei Ma, Huafeng Zhang, Ke Tang, Feiran Cheng, Yabo Zhou, Xiaohui Zhang, Ning Wang, Bo Huang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (2): 476–488.
https://doi.org/10.1158/0008-5472.CAN-20-2569
Published: 15 January 2021
View articletitled, Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells
Open the PDF for Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 6352: Potential anticancer role of secretion modification region (SMR) peptide reduces mortalin and HER2-overexpressing exosomes in human HER2-positive breast cancer cells

Free
Ming Bo Huang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6352.
https://doi.org/10.1158/1538-7445.AM2020-6352
Published: 15 August 2020
View articletitled, Abstract 6352: Potential anticancer role of secretion modification region (SMR) peptide reduces mortalin and HER2-overexpressing exosomes in human HER2-positive breast cancer cells
Journal Articles

Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Available to Purchase
Wenjie Huang, Bernat Navarro-Serer, Yea Ji Jeong, Peter Chianchiano, Limin Xia, Claudio Luchini, Nicola Veronese, Cameron Dowiak, Tammy Ng, Maria A. Trujillo, Bo Huang, Michael J. Pflüger, Anne M. Macgregor-Das, Gemma Lionheart, Danielle Jones, Kohei Fujikura, Kim-Vy Nguyen-Ngoc, Neil M. Neumann, Vincent P. Groot, Alina Hasanain, A. Floortje van Oosten, Sandra E. Fischer, Steven Gallinger, Aatur D. Singhi, Amer H. Zureikat, Randall E. Brand, Matthias M. Gaida, Stefan Heinrich, Richard A. Burkhart, Jin He, Christopher L. Wolfgang, Michael G. Goggins, Elizabeth D. Thompson, Nicholas J. Roberts, Andrew J. Ewald, Laura D. Wood
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2804–2817.
https://doi.org/10.1158/0008-5472.CAN-19-1523
Published: 02 July 2020
View articletitled, Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome
Open the PDF for Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome in another window
Includes: Multimedia, Supplementary data
Journal Articles

Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling

Free
Bo Huang, Jie Zhao, Shiqian Shen, Hongxing Li, Kai-Li He, Guan-Xin Shen, Lloyd Mayer, Jay Unkeless, Dong Li, Ye Yuan, Gui-Mei Zhang, Huabao Xiong, Zuo-Hua Feng
Journal: Cancer Research
Cancer Res (2019) 79 (16): 4306.
https://doi.org/10.1158/0008-5472.CAN-19-1891
Published: 15 August 2019
View articletitled, Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling
Open the PDF for Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling in another window
Journal Articles

Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance

Free
Bo Huang, Jie Zhao, Hongxing Li, Kai-Li He, Yibang Chen, Lloyd Mayer, Jay C. Unkeless, Huabao Xiong
Journal: Cancer Research
Cancer Res (2019) 79 (16): 4305.
https://doi.org/10.1158/0008-5472.CAN-19-1889
Published: 15 August 2019
View articletitled, Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance
Open the PDF for Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance in another window
Journal Articles

Abstract 3943: Inhibition of ribosomal protein RPS6KB1 as a strategy to improve conventional therapy for prostate cancer

Free
Alison D. Clark, Suleman S. Hussain, Shih-Bo Huang, Roble G. Bedolla, Mohammad A. Obeidat, Niko Papanikolaou, Chun Lin Lin, Tim H. Huang, Yogesh Gupta, Yidong Chen, Hiroshi Miyamoto, Rita Ghosh, Addanki P. Kumar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3943.
https://doi.org/10.1158/1538-7445.AM2019-3943
Published: 01 July 2019
View articletitled, Abstract 3943: Inhibition of ribosomal protein RPS6KB1 as a strategy to improve conventional therapy for prostate cancer
Journal Articles

Abstract 5082: SIRT1 functions as a double-edged sword in prostate cancer

Free
Shih-Bo Huang, Dinesh Thapa, Roble G. Bedolla, Amanda R. Muñoz, Xiaoyu Yang, Paul Rivas, Robert L. Reddick, Hiroshi Miyamoto, Rita Ghosh, Addanki Pratap Kumar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5082.
https://doi.org/10.1158/1538-7445.AM2019-5082
Published: 01 July 2019
View articletitled, Abstract 5082: SIRT1 functions as a double-edged sword in prostate cancer
Journal Articles

Abstract 116: Targeting glutamine addiction in pancreatic cancer

Free
Xiaoyu Yang, Amanda R. Muñoz, Shih-Bo Huang, Martha Hanes, Roble G. Bedolla, Divya Chakravarthy, Angel Su, Varsha Mulamreddy, Dmytro Kovalskyy, Paul Rivas, Joel Michalek, Rita Ghosh, Addanki P Kumar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 116.
https://doi.org/10.1158/1538-7445.AM2019-116
Published: 01 July 2019
View articletitled, Abstract 116: Targeting glutamine addiction in pancreatic cancer
Journal Articles

Abstract 2856: Secretion modification region (SMR) peptide blocks migration and invasion in human breast cancer cells

Free
Ming Bo Huang, Jennifer Y. Wu, William W. Roth, James Lillard, Vincent C. Bond
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2856.
https://doi.org/10.1158/1538-7445.AM2019-2856
Published: 01 July 2019
View articletitled, Abstract 2856: Secretion modification region (SMR) peptide blocks migration and invasion in human breast cancer cells
Journal Articles

Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program

Free
Yuying Liu, Jiadi Lv, Xiaoyu Liang, Xiaonan Yin, Le Zhang, Degao Chen, Xun Jin, Roland Fiskesund, Ke Tang, Jingwei Ma, Huafeng Zhang, Wenqian Dong, Siqi Mo, Tianzhen Zhang, Feiran Cheng, Yabo Zhou, Jing Xie, Ning Wang, Bo Huang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (14): 3926–3937.
https://doi.org/10.1158/0008-5472.CAN-17-3719
Published: 15 July 2018
View articletitled, Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program
Open the PDF for Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program in another window
Includes: Supplementary data
Journal Articles

Abstract 5823: Palmatine as a potential pancreatic cancer therapeutic agent

Free
Amanda R. Muñoz, Roble Bedolla, Shih-Bo Huang, Xiaou Yang, Paul Rivas, Robert Reddick, Martha Hanes, Glenn Halff, Rita Ghosh, Addanki P. Kumar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5823.
https://doi.org/10.1158/1538-7445.AM2018-5823
Published: 01 July 2018
View articletitled, Abstract 5823: Palmatine as a potential pancreatic cancer therapeutic agent
Journal Articles

Abstract 945: Novel role for SIRT1 in non-canonical activation of AR signaling

Free
Shih-Bo Huang, Dinesh Thapa, Amanda Muñoz, Roble G. Bedolla, Ratnesh Srivastav, Rita Ghosh, Addanki P. Kumar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 945.
https://doi.org/10.1158/1538-7445.AM2018-945
Published: 01 July 2018
View articletitled, Abstract 945: Novel role for SIRT1 in non-canonical activation of AR signaling