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Journal Articles

Abstract LB061: Proteomic-based stemness score measure oncogenic dedifferentiation and enable the identification of druggable targets

Tathiane M. Malta, Iga Kołodziejczak, Renan Simões, Antonio Colaprico, Erik Storrs, Francesca Petralia, Felipe da v Leprevost, Rossana L. Segura, Elizabeth Demicco, Alexander J. Lazar, Weiping Ma, Pietro Pugliese, Michele Ceccarelli, Bozena Kamińska, Alexey I. Nesvizhski, Bing Zhang, Henry Rodriguez, Mehdi Mesri, Ana I. Robles, Clinical Proteomic Tumor Analysis Consortium, Li Ding, Maciej Wiznerowicz
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB061.
https://doi.org/10.1158/1538-7445.AM2023-LB061
Published: 14 April 2023
View article titled, Abstract LB061: Proteomic-based stemness score measure oncogenic dedifferentiation and enable the identification of druggable targets
Journal Articles

Abstract 5726: Pan-cancer proteogenomics expands the landscape of therapeutic targets

Jonathan T. Lei, Sara R. Savage, Xinpei Yi, Bo Wen, Hongwei Zhao, Lauren K. Somes, Paul W. Shafer, Yongchao Dou, Qiang Gao, Valentina Hoyos, Bing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5726.
https://doi.org/10.1158/1538-7445.AM2023-5726
Published: 04 April 2023
View article titled, Abstract 5726: Pan-cancer proteogenomics expands the landscape of therapeutic targets
Journal Articles

Abstract 5717: Bridging the gap between clinical-omics and machine learning to improve cancer treatment

Chang In Moon, Byron Jia, Bing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5717.
https://doi.org/10.1158/1538-7445.AM2023-5717
Published: 04 April 2023
View article titled, Abstract 5717: Bridging the gap between clinical-omics and machine learning to improve cancer treatment
Journal Articles

Abstract 955: Proteogenomic insights suggest druggable pathways in endometrial cancer

Lizabeth Katsnelson, Yongchao Dou, Marina A. Gritsenko, Matthew L. Anderson, Karin D. Rodland, Bing Zhang, Tao Liu, David Fenyö, the Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 955.
https://doi.org/10.1158/1538-7445.AM2023-955
Published: 04 April 2023
View article titled, Abstract 955: Proteogenomic insights suggest druggable pathways in endometrial cancer
Journal Articles

Abstract 2023: CoPheeMap: a co-regulation map of 30,000 phosphosite illuminates the dark cancer phosphoproteome

Wen Jiang, Eric Jaehnig, Bing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2023.
https://doi.org/10.1158/1538-7445.AM2023-2023
Published: 04 April 2023
View article titled, Abstract 2023: CoPheeMap: a co-regulation map of 30,000 phosphosite illuminates the dark cancer phosphoproteome
Journal Articles

Abstract 6575: LinkedOmicsKB: A web portal to explore pan-cancer molecular and phenotype associations

Sara R. Savage, Yuxing Liao, Yongchao Dou, Zhiao Shi, Xinpei Yi, Wen Jiang, Jonathan T. Lei, Bing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6575.
https://doi.org/10.1158/1538-7445.AM2023-6575
Published: 04 April 2023
View article titled, Abstract 6575: LinkedOmicsKB: A web portal to explore pan-cancer molecular and phenotype associations
Journal Articles

Abstract 4492: A novel and potent FLT3 and IRAK4 dual inhibitor for the treatment of acute myeloid leukemia

Rui Yang, Lei Wu, Bing Zhang, Michael Xiang, Suyue Wang, Camille Xiang, Zhijian Lu, Jason Xiang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4492.
https://doi.org/10.1158/1538-7445.AM2023-4492
Published: 04 April 2023
View article titled, Abstract 4492: A novel and potent FLT3 and IRAK4 dual inhibitor for the treatment of acute myeloid leukemia
Journal Articles

Abstract P5-02-36: Proteogenomic profiling of fresh frozen core biopsies from CALGB 40601

Eric J. Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi Vashist, Matthew V. Holt, LaTerrica Williams, Jonathan Lei, Beom-Jun Kim, Yongchao Dou, Viktoriya Korchina, Richard Gibbs, Donna Muzny, Harshavardhan Doddapaneni, Henry Rodriguez, Ana Robles, Tara Hiltke, DR Mani, Michael Gillette, Terry Hyslop, Yujia Wen, Linda McCart, George Miles, Steven Carr, Bing Zhang, Shankha Satpathy, Matthew Ellis, Meenakshi Anurag
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-02-36.
https://doi.org/10.1158/1538-7445.SABCS22-P5-02-36
Published: 01 March 2023
View article titled, Abstract P5-02-36: Proteogenomic profiling of fresh frozen core biopsies from CALGB 40601
Journal Articles

Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer

Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-23-01.
https://doi.org/10.1158/1538-7445.SABCS22-P2-23-01
Published: 01 March 2023
View article titled, Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer
Journal Articles

Abstract P2-12-02: ClinicalomicsDB - Bridging the gap between clinical omics data and machine learning

Chang In Moon, Byron Jia, Bing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-12-02.
https://doi.org/10.1158/1538-7445.SABCS22-P2-12-02
Published: 01 March 2023
View article titled, Abstract P2-12-02: ClinicalomicsDB - Bridging the gap between clinical omics data and machine learning
Journal Articles

Abstract PD5-05: PD5-05 DAPK3 modulates migration and invasion of triple negative breast cancers

Junkai Wang, Beom-Jun Kim, Meenakshi Anurag, Xin Yu, Xiaoli Qi, Jin Wang, Bing Zhang, Chonghui Cheng, Matthew Ellis
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD5-05.
https://doi.org/10.1158/1538-7445.SABCS22-PD5-05
Published: 01 March 2023
View article titled, Abstract PD5-05: PD5-05 DAPK3 modulates migration and invasion of triple negative breast cancers
Journal Articles

Abstract 1010: LIG1 deletion predicts chemotherapy resistance, chromosomal instability, and poor prognosis in triple negative breast cancer

Meenakshi Anurag, Eric Jaehnig, Jonathan Lei, Beom-Jun Kim, Anh Minh Tran Huynh, Yongchao Dou, Tanmayi Vashist, Erik Bergstrom, Xuxu Gou, Viktoriya Korchina, Donna Marie Muzny, Kristen Otte, Harshavardhan Doddapaneni, Lacey Dobrolecki, Gloria Vittone Echeverria, Bora Lim, Mothaffar Rimawi, Karsten Krug, Ian Hageman, Henry Rodriguez, Ana I. Robles, Tara Hiltke, Kent Osborne, Michael Gillette, George Miles, Steven Carr, Michael T Lewis, Bing Zhang, Foluso Ademuyiwa, Shankha Satpathy, Matthew J. Ellis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1010.
https://doi.org/10.1158/1538-7445.AM2022-1010
Published: 15 June 2022
View article titled, Abstract 1010: LIG1 deletion predicts chemotherapy resistance, chromosomal instability, and poor prognosis in triple negative breast cancer
Journal Articles

Abstract 6187: ICP-723 is a potent pan-TRK Inhibitor with robust anti-tumor activities against wild-type and acquired drug-resistant mutations of NTRK fusions

Ruixia Liang, Chao Zhou, Yingrui Han, Prince Lu, Charles Ying Wang, Zuopeng Wang, Richard Liu, Norman Kong, Jason Bing Zhang, Jasmine Jisong Cui, Davy Xuesong Ouyang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6187.
https://doi.org/10.1158/1538-7445.AM2022-6187
Published: 15 June 2022
View article titled, Abstract 6187: ICP-723 is a potent pan-TRK Inhibitor with robust anti-tumor activities against wild-type and acquired drug-resistant mutations of NTRK fusions
Journal Articles

Abstract 1317: The role of PAX8 in copy number-high uterine cancers: Inflammatory cytokine modulation

Lauren Karnolt, Maja Okuka, Susan Read, Yongchao Dou, Bing Zhang, Thomas J. Rutherford, Matthew L. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1317.
https://doi.org/10.1158/1538-7445.AM2022-1317
Published: 15 June 2022
View article titled, Abstract 1317: The role of PAX8 in copy number-high uterine cancers: Inflammatory cytokine modulation
Journal Articles

Abstract PD3-04: Multi-omics characterization of triple-negative breast cancer identifies therapeutic vulnerabilities and epigenetic immune suppression in the mesenchymal subtype

Brian D Lehmann, Antonio Colaprico, Tiago C Silva, Jianjiao Chen, Hanbing An, Yuguang Ban, Lily Wang, Jamaal L James, Justin Balko, Paula I Gonzalez-Ericsson, Melinda E Sanders, Bing Zhang, Jennifer A Pietenpol, Xi S Chen
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD3-04.
https://doi.org/10.1158/1538-7445.SABCS21-PD3-04
Published: 15 February 2022
View article titled, Abstract PD3-04: Multi-omics characterization of triple-negative breast cancer identifies therapeutic vulnerabilities and epigenetic immune suppression in the mesenchymal subtype
Journal Articles

Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer

Jonathan T Lei, Chen Huang, Ramakrishnan R Srinivasan, Suhas Vasaikar, Lacey E Dobrolecki, Alaina N Lewis, Christina Sallas, Susan G Hilsenbeck, C. Kent Osborne, Mothaffar F Rimawi, Matthew J Ellis, Varduhi Petrosyan, Alexander B Saltzman, Anna Malovannaya, Gerburg Wulf, Daniel C Kraushaar, Tao Wang, Xi Chen, Gloria V Echeverria, Meenakshi Anurag, Bing Zhang, Michael T Lewis
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-07-01.
https://doi.org/10.1158/1538-7445.SABCS21-P5-07-01
Published: 15 February 2022
View article titled, Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer
Journal Articles

Abstract IA-003: Proteogenomic characterizations of pancreatic ductal adenocarcinoma

Liwei Cao, Chen Huang, Daniel Cui Zhou, Yingwei Hu, Mamie Lih, Sara R. Savage, Karsten Krug, David J. Clark, Michael Schnaubelt, Lijun Chen, Felipe da Veiga Leprevost, Rodrigo Vargas Eguez, Alexey I. Nesvizhskii, D.R. Mani, Gilbert S. Omenn, Emily S. Boja, Mehdi Mesri, Ana I. Robles, Henry Rodriguez, Oliver F. Bathe, Daniel W. Chan, Ralph H. Hruban, Li Ding, Bing Zhang, Hui Zhang, Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): IA-003.
https://doi.org/10.1158/1538-7445.PANCA21-IA-003
Published: 15 November 2021
View article titled, Abstract IA-003: Proteogenomic characterizations of pancreatic ductal adenocarcinoma
Journal Articles

Abstract 867: Incidence of molecular alterations in KRAS and other known cancer genes in patients with pancreatic cancer assessed with a commercial genomic profiling panel compared to TCGA results

Alexander D. Le, Bing Zhang, Kim C. Worley, David Wheeler, Benjamin L. Musher, Heidi Dowst, Amy Wood, Jeff Schaeffer, Nick Olsen, Lorenzo Grego, Matt Sonnleitner, William E. Fisher
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2021-867
Published: 01 July 2021
View article titled, Abstract 867: Incidence of molecular alterations in KRAS and other known cancer genes in patients with pancreatic cancer assessed with a commercial genomic profiling panel compared to TCGA results
Journal Articles

Abstract 1426: Multiomic analysis identifies CPT1A and fatty acid oxidation as a potential therapeutic target in platinum-refractory high grade serous ovarian cancer

Hong Wang, Dongqing Hugang, Shrabanti Chowdhury, Sara Savage, Richard Ivey, Jacob Kennedy, Jeffrey Whiteaker, Chenwei Lin, Xiaonan Hou, Catherine Huntoon, Uliana Voytovich, Zahra Shire, Qing Yu, Steven Gygi, Andrew Hoofnagle, Zachary Herbert, Anna Calinawan, Larry Karnitz, S. John Weroha, Scott Kaufmann, Bing Zhang, Pei Wang, Michael Birrer, Amanda Paulovich
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1426.
https://doi.org/10.1158/1538-7445.AM2021-1426
Published: 01 July 2021
View article titled, Abstract 1426: Multiomic analysis identifies CPT1A and fatty acid oxidation as a potential therapeutic target in platinum-refractory high grade serous ovarian cancer
Journal Articles

Abstract 17: Proteogenomic characterization of pancreatic ductal adenocarcinoma

Liwei Cao, Chen Huang, Daniel Cui Zhou, Oliver F. Bathe, Daniel W. Chan, Ralph H. Hruban, Li Ding, Bing Zhang, Hui Zhang, Clinical Proteomic Tumor Analysis Consortium Investigators
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 17.
https://doi.org/10.1158/1538-7445.AM2021-17
Published: 01 July 2021
View article titled, Abstract 17: Proteogenomic characterization of pancreatic ductal adenocarcinoma