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Journal Articles

Abstract LB032: HH102007 is a highly selective and potent PARP1 inhibitor and trapper

Yingjie Hou, Shanyun Gao, Shujuan Jiang, Jingjing Li, Chaobo Zhang, Yanxiao Xu, Songda Yu, Lei Liu, Bing Yu, Wangyang Tu, Yixiang Zhang, Leping Li
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB032.
https://doi.org/10.1158/1538-7445.AM2024-LB032
Published: 05 April 2024
View article titled, Abstract LB032: HH102007 is a highly selective and potent PARP1 inhibitor and trapper
Journal Articles

Abstract LB031: Discovery and Characterization of HH100937, a potent and selective SOS1 inhibitor demonstrates synergistic efficacy in combination with KRAS/MAPK therapies

Qing Xie, Dongsheng Li, Shujuan Jiang, Jie Zhu, Songda Yu, Maozhi Yang, Yalei Cai, Lei Liu, Bing Yu, Wangyang Tu, Yixiang Zhang, Leping Li
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB031.
https://doi.org/10.1158/1538-7445.AM2024-LB031
Published: 05 April 2024
View article titled, Abstract LB031: Discovery and Characterization of HH100937, a potent and selective SOS1 inhibitor demonstrates synergistic efficacy in combination with KRAS/MAPK therapies
Journal Articles

Abstract 4443: Trans-population two-sample Mendelian randomization study of circulating metabolites and prostate cancer risk

Harriett Fuller, Rebecca Rohde, Heather Highland, Jiayi Shen, Bing Yu, Eric Boerwinkle, Megan Grove, Kari E. North, David V. Conti, Christopher A. Haiman, Kristin Young, Burcu Darst
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4443.
https://doi.org/10.1158/1538-7445.AM2024-4443
Published: 22 March 2024
View article titled, Abstract 4443: Trans-population two-sample Mendelian randomization study of circulating metabolites and prostate cancer risk
Journal Articles

Abstract 2776: Real-time measurement of temperature and tissue damage during laser photothermal ablation

Faraneh Fathi, Dilip R. Maddirela, Venkateswara Rao Gogineni, Sarah B. White, Bing Yu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2776.
https://doi.org/10.1158/1538-7445.AM2020-2776
Published: 15 August 2020
View article titled, Abstract 2776: Real-time measurement of temperature and tissue damage during laser photothermal ablation
Journal Articles

Abstract 2927: Papaverine and its novel derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism

Martin Benej, Xiangqian Hong, Sandip Vibhute, Sabina Scott, Jinghai Wu, Edward Graves, Quynh-Thu Le, Albert C. Koong, Amato J. Giaccia, Ching-Shih Chen, Bing Yu, Ioanna Papandreou, Nicholas C. Denko
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2927.
https://doi.org/10.1158/1538-7445.AM2019-2927
Published: 01 July 2019
View article titled, Abstract 2927: Papaverine and its novel derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism
Journal Articles

Abstract LB-005: Allosteric SHP2 phosphatase inhibition: Multiple mechanisms and chemotypes

Matthew J. LaMarche, Jeff Bagdanoff, Mike Acker, Ying-Nan Chen, Homan Chan, Michael Dore, Brant Firestone, Michelle Fodor, Jorge Garcia-Fortanet, Murphy Hentemann, Mitsunori Kato, Robert Koenig, Laura La Bonte, Shumei Liu, Movarid Mohseni, Rukundo Ntaganda, Patrick Sarver, Troy Smith, Martin Sendzik, Travis Stams, Stan Spence, Chris Towler, Hongyun Wang, Ping Wang, Sarah Williams, Zhouliang Chen, Huaixiang Hao, Gang Liu, Chen Liu, Eric McNeill, Bing Yu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-005.
https://doi.org/10.1158/1538-7445.AM2019-LB-005
Published: 01 July 2019
View article titled, Abstract LB-005: Allosteric SHP2 phosphatase inhibition: Multiple mechanisms and chemotypes
Journal Articles

Abstract 983: Metabolic radiosensitization: Overcoming the radioresistance of hypoxic tumors by targeting OXPHOS

Martin Benej, Xiangqian Hong, Bing Yu, Ioanna Papandreou, Nicholas Denko
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 983.
https://doi.org/10.1158/1538-7445.AM2018-983
Published: 01 July 2018
View article titled, Abstract 983: Metabolic radiosensitization: Overcoming the radioresistance of hypoxic tumors by targeting OXPHOS
Journal Articles

Abstract 3269: Impact of gender on survival of the patients with esophageal squamous cell carcinoma at a single institute in China

Jian Liang Lu, Jian Liang Lu, Rui Ping Xu, Bei Li, Li Xin Wan, Ming Yao Chen, Chun Jiang Liu, Zhan Qiang Han, Fang Fang Shen, Jian Bo Zhao, Hai Zhou Guo, Wei Cao, Bing Yu Fan, Li Dong Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3269.
https://doi.org/10.1158/1538-7445.AM2017-3269
Published: 01 July 2017
View article titled, Abstract 3269: Impact of gender on survival of the patients with esophageal squamous cell carcinoma at a single institute in China
Journal Articles

Abstract 4238: COnsortium for METabolomics Studies (COMETS): leveraging resources to accelerate scientific discovery

Rachael Z. Stolzenberg-Solomon, Steven Moore, Crnelia Ulrich, Elizabeth Poole, Marinella Temprosa, Mukesh Verma, Demetrius Albanes, Clara Barrios Barrera, Eric Boerwinkle, Juan P. Casas, Clary Clish, Robert Gerszten, Christian Gieger, Marc Gunter, Sei Harada, Tamara Harris, David Herrington, Ann Hsing, Mattias Johannson, Claudia Langenberg, Jessica Lasky-Su, Loic Le Marchand, Charles Matthews, Cristina Menni, Matej Oresic, Eric Orwoll, Alexandre Pereira, Kathyrn Rexrode, Svati Shah, Xiao-ou Shu, Victoria Stevens, Bing Yu, Hua Zhao, Krista Zanetti
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4238.
https://doi.org/10.1158/1538-7445.AM2017-4238
Published: 01 July 2017
View article titled, Abstract 4238: COnsortium for METabolomics Studies (COMETS): leveraging resources to accelerate scientific discovery
Journal Articles

Abstract 5841: Hypoxic tumors can be sensitized to radiation therapy by repurposing papaverine as an inhibitor of mitochondrial respiration

Martin Benej, Ioanna Papandreou, Xiangqian Hong, Bing Yu, Nicholas Denko
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5841.
https://doi.org/10.1158/1538-7445.AM2017-5841
Published: 01 July 2017
View article titled, Abstract 5841: Hypoxic tumors can be sensitized to radiation therapy by repurposing papaverine as an inhibitor of mitochondrial respiration
Journal Articles

CDK1 Regulates Mediator of DNA Damage Checkpoint 1 during Mitotic DNA Damage

Bing Yu, W. Brian Dalton, Vincent W. Yang
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5448–5453.
https://doi.org/10.1158/0008-5472.CAN-12-2354
Published: 31 October 2012
View article titled, CDK1 Regulates Mediator of DNA Damage Checkpoint 1 during Mitotic DNA Damage
Open the PDF for CDK1 Regulates Mediator of DNA Damage Checkpoint 1 during Mitotic DNA Damage in another window
Includes: Supplementary data
Journal Articles

Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

Jessica D. Kessler, Kristopher T. Kahle, Tingting Sun, Kristen L. Meerbrey, Michael R. Schlabach, Earlene M. Schmitt, Samuel O. Skinner, Qikai Xu, Mamie Z. Li, Zachary C. Hartman, Mitchell Rao, Peng Yu, Rocio Dominguez-Vidana, Anthony C. Liang, Nicole L. Solimini, Ronald J. Bernardi, Bing Yu, Tiffany Hsu, Ido Golding, Ji Luo, C. Kent Osborne, Chad Creighton, Susan G. Hilsenbeck, Rachel Schiff, Chad A. Shaw, Stephen J. Elledge, Thomas F. Westbrook
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3091.
https://doi.org/10.1158/1538-7445.AM2012-3091
Published: 15 April 2012
View article titled, Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Journal Articles

Abstract 2028: Krüppel-like factor 4 null mouse embryonic fibroblasts exhibit DNA repair defects post exposure to gamma-irradiation

Hagos Engda, Vincent W. Yang, Bing Yu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2028.
https://doi.org/10.1158/1538-7445.AM2012-2028
Published: 15 April 2012
View article titled, Abstract 2028: Krüppel-like factor 4 null mouse embryonic fibroblasts exhibit DNA repair defects post exposure to gamma-irradiation
Journal Articles

Abstract 3890: Regulation of mediator of DNA damage checkpoint 1 (MDC1) during mitosis

Bing Yu, William B. Dalton, Vincent W. Yang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3890.
https://doi.org/10.1158/1538-7445.AM2011-3890
Published: 15 April 2011
View article titled, Abstract 3890: Regulation of mediator of DNA damage checkpoint 1 (MDC1) during mitosis
Journal Articles

c-Jun Protects Hypoxia-Inducible Factor-1α from Degradation via Its Oxygen-Dependent Degradation Domain in a Nontranscriptional Manner

Bing Yu, Ze-Hong Miao, Yi Jiang, Mei-Hong Li, Na Yang, Ting Li, Jian Ding
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7704–7712.
https://doi.org/10.1158/0008-5472.CAN-09-0808
Published: 01 October 2009
View article titled, c-Jun Protects Hypoxia-Inducible Factor-1α from Degradation via Its Oxygen-Dependent Degradation Domain in a Nontranscriptional Manner
Open the PDF for c-Jun Protects Hypoxia-Inducible Factor-1α from Degradation via Its Oxygen-Dependent Degradation Domain in a Nontranscriptional Manner in another window
Includes: Supplementary data
Journal Articles

Abstract #228: c-Jun protects HIF-1\#945; from degradation via binding to ODD domain in a non-transcriptional manner

Bing Yu, Ze-Hong Miao, Yi Jiang, Mei-Hong Li Li, Na Yang Yang, Ting Li, Jian Ding
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 228.
Published: 01 May 2009
View article titled, Abstract #228: c-Jun protects HIF-1\#945; from degradation via binding to ODD domain in a non-transcriptional manner
Journal Articles

Interdependence of homologous recombination repair and cell cycle arrest in response to DNA double strand breaks induced by camptothecins

Min Huang, Hong Zhu, Zehong Miao, Bing Yu, Wei Lu, Jian Ding
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1971.
Published: 01 May 2007
View article titled, Interdependence of homologous recombination repair and cell cycle arrest in response to DNA double strand breaks induced by camptothecins