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Journal Articles

Abstract 5307: New developments in spatial transcriptomics unlock insights into the tumor microenvironment

Free
Manisha Ray, Justin He, Bin Wang, Bing Yang, Sudhir Tattikota, Timothy Wiggin, Hao Wang, Jichuan Zhang, Lizi Maziashvili, Alexander Genshaft, Peter Reinhold, Brittany Auclair, Robert Mathis, Shawn Wang, Jiang He, George Emanuel
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5307.
https://doi.org/10.1158/1538-7445.AM2025-5307
Published: 21 April 2025
View articletitled, Abstract 5307: New developments in spatial transcriptomics unlock insights into the tumor microenvironment
Journal Articles

Abstract 6072: Engineering and preclinical development of an anti-TROP2/PD-L1 bispecific antibody drug conjugate (ADC) for enhanced anti-tumor efficacy

Free
Chuan Chen, Liang Tian, Chenpeng Su, Dandan Liu, Jiyuan Tian, Yujuan Li, Bing Yang, Yongxin Shan, Xiaoqian Chen, Jian Peng, Zhenping Zhu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6072.
https://doi.org/10.1158/1538-7445.AM2025-6072
Published: 21 April 2025
View articletitled, Abstract 6072: Engineering and preclinical development of an anti-TROP2/PD-L1 bispecific antibody drug conjugate (ADC) for enhanced anti-tumor efficacy
Journal Articles

Abstract 3550: PerturbDB: A resource for revealing gene functions and cancer-associated phenotypes

Free
Bing Yang, Man Zhang, Yanmei Shi, Yi-Ming Dong, Xingyu Ma, Jingyuan Zhang, Daning Lu, Jian-You Liao, Dong Yin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3550.
https://doi.org/10.1158/1538-7445.AM2024-3550
Published: 22 March 2024
View articletitled, Abstract 3550: PerturbDB: A resource for revealing gene functions and cancer-associated phenotypes
Journal Articles

Abstract 6714: AI-guided tailor-made anti-TROP2 T-cell engagers for T-cell mediated cancer immunotherapy with enhanced therapeutic index

Free
Chuan Chen, Liang Tian, Chenpeng Su, Dandan Liu, Xiaoqian Chen, Yifei Zhou, Suze Jiang, Guifang Wang, Jiyuan Tian, Yuan Yuan, Bing Yang, Jian Peng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6714.
https://doi.org/10.1158/1538-7445.AM2024-6714
Published: 22 March 2024
View articletitled, Abstract 6714: AI-guided tailor-made anti-TROP2 T-cell engagers for T-cell mediated cancer immunotherapy with enhanced therapeutic index
Journal Articles

Abstract A060: Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer

Free
Tanaya A. Purohit, Joseph Gawdzik, Bing Yang, Eric A. Armstrong, Peter W. Lewis, John M. Denu, David F. Jarrard
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A060.
https://doi.org/10.1158/1538-7445.PRCA2023-A060
Published: 02 June 2023
View articletitled, Abstract A060: Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer
Journal Articles

Abstract B051: Alterations in SIRT2-H3K18Ac identify increased P300 activity in circulating tumor cells from patients with CRPC

Free
Mikolaj Filon, Bing Yang, Jennifer Schehr, Anupama Singh, Marcelo Bigarella, John Denu, Joshua Lang, David Jarrard
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B051.
https://doi.org/10.1158/1538-7445.PRCA2023-B051
Published: 02 June 2023
View articletitled, Abstract B051: Alterations in SIRT2-H3K18Ac identify increased P300 activity in circulating tumor cells from patients with CRPC
Journal Articles

Abstract 4296: Fast de novo antibody structure prediction with atomic accuracy

Free
Yining Wang, Xumeng Gong, Shaochuan Li, Bing Yang, Yiwu Sun, Yujie Luo, Hui Li, Le Song
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4296.
https://doi.org/10.1158/1538-7445.AM2023-4296
Published: 04 April 2023
View articletitled, Abstract 4296: Fast de novo antibody structure prediction with atomic accuracy
Journal Articles

PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells

Available to Purchase
Yun Li, Hengxing Chen, Xuan Xie, Bing Yang, Xiaojuan Wang, Jingyuan Zhang, Tian Qiao, Jiao Guan, Yuntan Qiu, Yong-Xin Huang, Duanqing Tian, Xinyi Yao, Daning Lu, H. Phillip Koeffler, Yin Zhang, Dong Yin
Journal: Cancer Research
Cancer Res (2023) 83 (3): 398–413.
https://doi.org/10.1158/0008-5472.CAN-22-2370
Published: 03 February 2023
View articletitled, PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells
Open the PDF for PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 1861: Advancing bispecific antibody discovery using common light chain immunoglobulin humanized mouse

Free
Li Hui, Hui Lu, Yabo Zhang, Shuwen Huang, Ping Zhang, Huizhen Zhao, Ruifang Chang, Bing Yang, Fengqian Zhang, Wendong Yang, Fang Yang, Hao Yang, Jiawei Yao, Lei Chen, Qingcong Lin
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1861.
https://doi.org/10.1158/1538-7445.AM2021-1861
Published: 01 July 2021
View articletitled, Abstract 1861: Advancing bispecific antibody discovery using common light chain immunoglobulin humanized mouse
Journal Articles

Loss of Igf2 Gene Imprinting in Murine Prostate Promotes Widespread Neoplastic Growth

Free
Nathan A. Damaschke, Bing Yang, Sachin Bhusari, Mele Avilla, Weixiong Zhong, Michael L. Blute, Jr, Wei Huang, David F. Jarrard
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5236–5247.
https://doi.org/10.1158/0008-5472.CAN-16-3089
Published: 01 October 2017
View articletitled, Loss of Igf2 Gene Imprinting in Murine Prostate Promotes Widespread Neoplastic Growth
Open the PDF for Loss of Igf2 Gene Imprinting in Murine Prostate Promotes Widespread Neoplastic Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 5389: A personalized medicine approach to identifying dysregulated epigenetic enzyme activity in the development of castrate-resistant prostate cancer

Free
Jin-Hee Lee, Melissa Boersma, Bing Yang, Nathan Damaschke, Eva Corey, John Denu, David F. Jarrard
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5389.
https://doi.org/10.1158/1538-7445.AM2017-5389
Published: 01 July 2017
View articletitled, Abstract 5389: A personalized medicine approach to identifying dysregulated epigenetic enzyme activity in the development of castrate-resistant prostate cancer
Journal Articles

Abstract 2861: Dose-dependent tissue distribution and tumor targeting of Notch3-ADC using fluorescence molecular tomography imaging

Free
Anand Giddabasappa, Parul Gupta, Mauricio Leal, Jonathan Golas, Fengping Li, Bing Yang, Antonio Esparza, Christopher Winkelmann, Kenneth Geles
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2861.
https://doi.org/10.1158/1538-7445.AM2017-2861
Published: 01 July 2017
View articletitled, Abstract 2861: Dose-dependent tissue distribution and tumor targeting of Notch3-ADC using fluorescence molecular tomography imaging
Journal Articles

Abstract 2390: Clinical validation of an epigenetic field of susceptibility to detect significant prostate cancer from 2 non-tumor biopsies

Free
Bing Yang, Johnathon McCormick, Adam Schultz, Glen Leverson, Geoffrey Sonn, Cristina Magi-Galluzi, Eric A. Klein, Michael Fumo, David F. Jarrard
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2390.
https://doi.org/10.1158/1538-7445.AM2017-2390
Published: 01 July 2017
View articletitled, Abstract 2390: Clinical validation of an epigenetic field of susceptibility to detect significant prostate cancer from 2 non-tumor biopsies
Journal Articles

Abstract 3391: SCUBE2 is a co-receptor for VEGFR2 in tumor angiogenesis

Free
Yuh-Charn Lin, Ruey-Bing Yang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3391.
https://doi.org/10.1158/1538-7445.AM2016-3391
Published: 15 July 2016
View articletitled, Abstract 3391: SCUBE2 is a co-receptor for VEGFR2 in tumor angiogenesis
Journal Articles

Abstract 4434: CTCF acts as a master regulator to direct epigenetic events important for tumor development and progression

Free
Nathan A. Damaschke, Bing Yang, Anastasia Montgomery, John Svaren, Avtar Roopra, Jianhua Luo, Sunduz Keles, David Jarrard
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4434.
https://doi.org/10.1158/1538-7445.AM2016-4434
Published: 15 July 2016
View articletitled, Abstract 4434: CTCF acts as a master regulator to direct epigenetic events important for tumor development and progression
Journal Articles

Abstract 4341: Employing the epigenetic field effect to detect prostate cancer in biopsy-negative patients

Free
Bing Yang, Johnathon McCormick, Nathan Damaschke, Anastasia Montgomery, Glen Leverson, Wei Huang, Daniel W. Lin, David F. Jarrard
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4341.
https://doi.org/10.1158/1538-7445.AM2016-4341
Published: 15 July 2016
View articletitled, Abstract 4341: Employing the epigenetic field effect to detect prostate cancer in biopsy-negative patients
Journal Articles

Abstract 595: Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition

Free
Yuh-Charn Lin, Yi-Ching Lee, Ling-Hui Li, Chien-Jui Cheng, Ruey-Bing Yang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 595.
https://doi.org/10.1158/1538-7445.AM2014-595
Published: 01 October 2014
View articletitled, Abstract 595: Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition
Journal Articles

Abstract LB-75: Concomitant use of panitumumab (Pmab) had no clinically significant effect on irinotecan (Iri) pharmacokinetics (PK)

Free
Hagen Kennecke, Chi-Yuan Wu, Eric Chen, Jeffrey Infante, Alin Chen, Bing Gao, Brian Smith, Jason Litten, Bing-Bing Yang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-75.
https://doi.org/10.1158/1538-7445.AM10-LB-75
Published: 15 April 2010
View articletitled, Abstract LB-75: Concomitant use of panitumumab (Pmab) had no clinically significant effect on irinotecan (Iri) pharmacokinetics (PK)
Journal Articles

An Optimized Telomerase-Specific Lentivirus for Optical Imaging of Tumors

Free
Song-Tao Yu, Yin-Bing Yang, Guang-Ping Liang, Chuan Li, Ling Chen, Chun-Meng Shi, Xu-Dong Tang, Chang-Zhu Li, Ling Li, Guo-Zheng Wang, Yu-Yun Wu, Shi-Ming Yang, Dian-Chun Fang
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2585–2594.
https://doi.org/10.1158/0008-5472.CAN-09-3841
Published: 31 March 2010
View articletitled, An Optimized Telomerase-Specific Lentivirus for Optical Imaging of Tumors
Open the PDF for An Optimized Telomerase-Specific Lentivirus for Optical Imaging of Tumors in another window
Journal Articles

Abstract #3891: SCUBE3 functions as a novel invasion promoter in lung cancer progression

Free
Yi-Ying Wu, Szu-Hua Pan, Jau-Chen Lin, Konan Peck, Ruey-Bing Yang, Tse-Ming Hong, Pan-Chyr Yang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3891.
Published: 01 May 2009
View articletitled, Abstract #3891: SCUBE3 functions as a novel invasion promoter in lung cancer progression