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Journal Articles

Abstract PO1-03-11: Camrelizumab in Combination with Nab-Paclitaxel and Carboplatin versus Nab-Paclitaxel and Carboplatin as Neoadjuvant Therapy for Triple Negative Breast Cancer: A Multicenter, Open-Label, Randomized Controlled Study

Weipeng Zhao, Xin Wang, Bin Zhang, Yehui Shi, Chen Wang, Xu Wang, Shufen Li, Chunfang Hao, Ning Lu, Yongsheng Jia, Li Zhang, Lan Zhang, Weixin Sun, Xuchen Cao, Zhongsheng Tong
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-03-11.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-03-11
Published: 02 May 2024
View article titled, Abstract PO1-03-11: Camrelizumab in Combination with Nab-Paclitaxel and Carboplatin versus Nab-Paclitaxel and Carboplatin as Neoadjuvant Therapy for Triple Negative Breast Cancer: A Multicenter, Open-Label, Randomized Controlled Study
Journal Articles

Abstract CT165: A phase 1/2a, multicenter, open-label, first-in-human study to assess the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of DB-1311 (a B7-H3-targeting ADC) in patients with advanced/metastatic solid tumors

Ying Cheng, Aaron Lisberg, Charlotte Lemech, Afaf Abed, Arvind Chaudhry, Andrew Schmidt, Xin Lu, Zhongyuan Zhu, Wei Gu, Yang Qiu, Rong Shi, Bin Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT165.
https://doi.org/10.1158/1538-7445.AM2024-CT165
Published: 05 April 2024
View article titled, Abstract CT165: A phase 1/2a, multicenter, open-label, first-in-human study to assess the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of DB-1311 (a B7-H3-targeting ADC) in patients with advanced/metastatic solid tumors
Journal Articles

Abstract 7397: Application of state transition theory for predicting responses of acute myeloid leukemia to chemotherapy

Lisa Uechi, Yu-Hsuan Fu, David E. Frankhouser, Lianjun Zhang, Ying-Chieh Chen, Denis O'Meally, Sergio Branciamore, Jihyun Irizarry, Bin Zhang, Guido Marcucci, Ya-Huei Kuo, Russell C. Rockne
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7397.
https://doi.org/10.1158/1538-7445.AM2024-7397
Published: 22 March 2024
View article titled, Abstract 7397: Application of state transition theory for predicting responses of acute myeloid leukemia to chemotherapy
Journal Articles

Abstract 2307: State-transition modeling of blood transcriptome predicts disease evolution and treatment response in chronic myeloid leukemia (CML)

David E. Frankhouser, Russell C. Rockne, Dandan Zhao, Sergio Branciamore, Lisa Uechi, Denis O'Meally, Yu-Hsuan Fu, Ya-Huei Kuo, Bin Zhang, Guido Marcucci
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2307.
https://doi.org/10.1158/1538-7445.AM2024-2307
Published: 22 March 2024
View article titled, Abstract 2307: State-transition modeling of blood transcriptome predicts disease evolution and treatment response in chronic myeloid leukemia (CML)
Journal Articles

Abstract 7047: Comparative analysis of transcriptomic and immunological profiles in treatment-naïve black and non-Hispanic White women with high-grade serous ovarian cancer

Hao Huang, Russel Keathley, Ujin Kim Kim, Horacio Cardenas, Ping Xie, Jianjun Wei, Guangyuan Zhao, Emma L. Barber, Ernst Lengyel, Kenneth P. Nephew, Victoria Bae-Jump, Bin Zhang, Daniela Matei
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7047.
https://doi.org/10.1158/1538-7445.AM2024-7047
Published: 22 March 2024
View article titled, Abstract 7047: Comparative analysis of transcriptomic and immunological profiles in treatment-naïve black and non-Hispanic White women with high-grade serous ovarian cancer
Journal Articles

Abstract 481: Proteomimetic polymers limit tumor growth in multiple models via potent antigen-specific T cell activation

Max Wang, Miran Choi, Bin Zhang, Nathan Gianneschi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 481.
https://doi.org/10.1158/1538-7445.AM2024-481
Published: 22 March 2024
View article titled, Abstract 481: Proteomimetic polymers limit tumor growth in multiple models via potent antigen-specific T cell activation
Journal Articles

Abstract 4356: An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing

Zhongxiao Li, Bin Zhang, Jia Jia Chan, Hossein Tabatabaeian, Qing Yun Tong, Xiao Hong Chew, Xiaonan Fan, Charlene Chan, Patrick Driguez, Faith Cheong, Shi Wang, Bei En Siew, Ian Jse-Wei Tan, Kai-Yin Lee, Bettina Lieske, Wai-Kit Cheong, Dennis Kappei, Ker-Kan Tan, Xin Gao, Yvonne Tay
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4356.
https://doi.org/10.1158/1538-7445.AM2024-4356
Published: 22 March 2024
View article titled, Abstract 4356: An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing
Journal Articles

Abstract 4535: Clinical outcomes and molecular features of different histopathologic patterns in patients with stage IB non-squamous non-small-cell lung cancer

Dongsheng Yue, Bin Zhang, Chen Chen, Qiang Zhang, Xinyi Wu, Jiping Xie, Changli Wang, Zhenfa Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4535.
https://doi.org/10.1158/1538-7445.AM2023-4535
Published: 04 April 2023
View article titled, Abstract 4535: Clinical outcomes and molecular features of different histopathologic patterns in patients with stage IB non-squamous non-small-cell lung cancer
Journal Articles

Abstract 4013: Combination of BTK inhibitor orelabrutinib, anti-CD19 antibody tafasitamab, and IMiD lenalidomide for the treatment of B cell malignancies

Hongjuan Zhang, Ruixia Liang, Haipeng Xu, Xiaorong Li, Renbin Zhao, Jason Bin Zhang, Davy Xuesong Ouyang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4013.
https://doi.org/10.1158/1538-7445.AM2023-4013
Published: 04 April 2023
View article titled, Abstract 4013: Combination of BTK inhibitor orelabrutinib, anti-CD19 antibody tafasitamab, and IMiD lenalidomide for the treatment of B cell malignancies
Journal Articles

Abstract 4012: Preclinical development of SHP2 allosteric inhibitor ICP-189

Ruixia Liang, Yingxiang Gao, Fangfang Yang, Yingrui Han, Zuopeng Wang, Richard Liu, Charles Ying Wang, Jason Bin Zhang, Xiangyang Chen, Davy Xuesong Ouyang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4012.
https://doi.org/10.1158/1538-7445.AM2023-4012
Published: 04 April 2023
View article titled, Abstract 4012: Preclinical development of SHP2 allosteric inhibitor ICP-189
Journal Articles

Abstract 3427: ICP-490 is a highly potent and selective IKZF1/3 degrader with robust anti-tumor activities against multiple myeloma and non-Hodgkin’s lymphoma

Ruixia Liang, Yucheng Pang, Yingrui Han, Haipeng Xu, Zuopeng Wang, Richard Liu, Charles Ying Wang, Jason Bin Zhang, Xiangyang Chen, Davy Xuesong Ouyang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3427.
https://doi.org/10.1158/1538-7445.AM2023-3427
Published: 04 April 2023
View article titled, Abstract 3427: ICP-490 is a highly potent and selective IKZF1/3 degrader with robust anti-tumor activities against multiple myeloma and non-Hodgkin’s lymphoma
Journal Articles

Abstract 813: The protein-like polymer (PLP): A tunable proteomimetic nanoplatform for the development of rationally designed cancer vaccines

Max M. Wang, Mi Ran Choi, Brayley Gattis, Bin Zhang, Nathan C. Gianneschi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 813.
https://doi.org/10.1158/1538-7445.AM2023-813
Published: 04 April 2023
View article titled, Abstract 813: The protein-like polymer (PLP): A tunable proteomimetic nanoplatform for the development of rationally designed cancer vaccines
Journal Articles

Abstract 2323: ZGGS18, a bispecific drug candidate of anti-VEGF and TGFbeta-trap, inhibiting tumor proliferation and improving tumor microenvironment with I/O therapy

Ruifeng Liu, Alfonso Suarez, Tyler Liban, Bin Zhang, Tongcheng Dai, Margaret Karow, Jackie Sheng, Zelin Sheng, Binhua Lv, Bing Zhu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2323.
https://doi.org/10.1158/1538-7445.AM2023-2323
Published: 04 April 2023
View article titled, Abstract 2323: ZGGS18, a bispecific drug candidate of anti-VEGF and TGFbeta-trap, inhibiting tumor proliferation and improving tumor microenvironment with I/O therapy
Journal Articles

Abstract 6068: Methylomic, transcriptomic and immune profiles of high grade serous ovarian cancer among Black and non-Hispanic White women

Hao Huang, Russell Keathley, Ping Xie, JianJun Wei, Ernst Lengyel, Bin Zhang, Daniela Matei
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6068.
https://doi.org/10.1158/1538-7445.AM2023-6068
Published: 04 April 2023
View article titled, Abstract 6068: Methylomic, transcriptomic and immune profiles of high grade serous ovarian cancer among Black and non-Hispanic White women
Journal Articles

Abstract 6368: Preclinical pharmacology and safety studies of ZG005: an anti-PD-1/TIGIT bispecific mAb in a phase I clinical trial for advanced tumors

Bing Zhu, Tongcheng Dai, Ruifeng Liu, Alfonso Suarez, Tyler Liban, Bin Zhang, Margaret Karow, Jackie Sheng, Zelin Sheng, Binhua Lv
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6368.
https://doi.org/10.1158/1538-7445.AM2023-6368
Published: 04 April 2023
View article titled, Abstract 6368: Preclinical pharmacology and safety studies of ZG005: an anti-PD-1/TIGIT bispecific mAb in a phase I clinical trial for advanced tumors
Journal Articles

Abstract 6540: Multiscale protein networks: de novo aberrant protein interactions and oncogenic regulators in seven cancer types

Won Min Song, Abdulkadir Elmas, Richard Farias, Peng Xu, Xianxiao Zhou, Benjamin Hopkins, Kuan-lin Huang, Bin Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6540.
https://doi.org/10.1158/1538-7445.AM2023-6540
Published: 04 April 2023
View article titled, Abstract 6540: Multiscale protein networks: de novo aberrant protein interactions and oncogenic regulators in seven cancer types
Journal Articles

Abstract 924: Modelling the metastatic castration-resistant prostate cancer in mice by orthotopic delivering multiplexed gRNAs of CRISPR/Cas9 based on AAV system

Huiqiang Cai, Bin Zhang, Johanne Ahrenfeldt, Nicolai Birkbak, Martin Thomsen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 924.
https://doi.org/10.1158/1538-7445.AM2022-924
Published: 15 June 2022
View article titled, Abstract 924: Modelling the metastatic castration-resistant prostate cancer in mice by orthotopic delivering multiplexed gRNAs of CRISPR/Cas9 based on AAV system
Journal Articles

Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development

Zhi Hao Kwok, Bin Zhang, Xiao Hong Chew, Jia Jia Chan, Velda Teh, Henry Yang, Dennis Kappei, Yvonne Tay
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1308–1320.
https://doi.org/10.1158/0008-5472.CAN-20-1406
Published: 01 March 2021
View article titled, Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent <em>FTX</em> Locus to Promote Colon Cancer Development
Open the PDF for Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent <em>FTX</em> Locus to Promote Colon Cancer Development in another window
Includes: Supplementary data
Journal Articles

Abstract 38: Large-scale study of NTRK fusions in Chinese solid tumors and using next generation sequencing: A multicenter study

Wen-xian Wang, Chun-wei Xu, Lei Lei, Xiao-jia Wang, You-cai Zhu, Yong Fang, Xiu-yu Cai, Rong-bo Lin, Li Lin, Hong Wang, Mei-yu Fang, Yin-bin Zhang, Shi-jie Lan, Xin Cai, Xin Liu, Xing-xiang Pu, Zong-yang Yu, Bing Wan, Jin-luan Li, Xian-bin Liang, Li-ping Wang, Wu Zhuang, Zi-yan Yang, Gang Chen, Tang-feng Lv, Yong Song
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 38.
https://doi.org/10.1158/1538-7445.AM2020-38
Published: 15 August 2020
View article titled, Abstract 38: Large-scale study of NTRK fusions in Chinese solid tumors and using next generation sequencing: A multicenter study
Journal Articles

Abstract CT132: Orelabrutinib, a potent and selective Bruton's tyrosine kinase inhibitor with superior safety profile and excellent PK/PD properties

Bin Zhang, Renbin Zhao, Ruixia Liang, Yingxiang Gao, Richard Liu, Xiangyang Chen, Zhengguang Lu, Zuopeng Wang, Liqin Yu, Sepehr Shakib, Jisong Cui
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT132.
https://doi.org/10.1158/1538-7445.AM2020-CT132
Published: 15 August 2020
View article titled, Abstract CT132: Orelabrutinib, a potent and selective Bruton's tyrosine kinase inhibitor with superior safety profile and excellent PK/PD properties