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Journal Articles

Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies

Jing Han Hong, Chern Han Yong, Hong Lee Heng, Jason Yongsheng Chan, Mai Chan Lau, Jianfeng Chen, Jing Yi Lee, Abner Herbert Lim, Zhimei Li, Peiyong Guan, Pek Lim Chu, Sheng Rong Ng, Xiaosai Yao, Peili Wang, Rong Xiao, Xian Zeng, Yichen Sun, Wei Liu, Joanna Koh, Felicia Yu Ting Wee, Jeffrey Chun Tatt Lim, Cedric Chuan Young Ng, Xiu Yi Kwek, Poramate Klanrit, Yaojun Zhang, Jiaming Lai, David Wai Meng Tai, Chawalit Pairojkul, Simona Dima, Irinel Popescu, Sen-Yung Hsieh, Ming-Chin Yu, Joe Yeong, Sarinya Kongpetch, Apinya Jusakul, Watcharin Loilome, Patrick Tan, Jing Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2024) 84 (8_Supplement): LT09.
https://doi.org/10.1158/1538-7445.FCS2023-LT09
Published: 15 April 2024
View article titled, Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies
Journal Articles

Abstract 6399: Real-world experience of an Asian pan-cancer combined DNA/RNA next generation sequencing (NGS) tissue biopsy assay

Jason Yongsheng Chan, Jing Yi Lee, Zi Yi Wan, Abner Herbert Lim, Tun Kiat Ko, Cedric Chuan-Young Ng, Donald Poon, Jens Samol, Tsz Him So, Su Pin Choo, Ravindran Kanesvaran, Cheng-Vai Hui, Joseph Siu-Kie Au, Aya El Helali, Timothy Yip, Vikneswari Rajasegaran, Sandy Lim, Ruifen Weng, Puay Hoon Tan, Bin Tean Teh, Min-Han Tan, Jonathan Poh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6399.
https://doi.org/10.1158/1538-7445.AM2024-6399
Published: 22 March 2024
View article titled, Abstract 6399: Real-world experience of an Asian pan-cancer combined DNA/RNA next generation sequencing (NGS) tissue biopsy assay
Journal Articles

Abstract 7276: Potent anti-proliferative activity of brincidofovir in Diffuse Large B-cell Lymphoma with overexpression of transcriptional repressor TLE1

Jing Yi Lee, Tun Kiat Ko, Elizabeth Chun Yong Lee, Bavani Kannan, Boon Yee Lim, Zhimei Li, Zexi Guo, Jui Wan Loh, Cedric Chuan-Young Ng, Kelila Xin Ye Chai, Nur Ayuni Binte Muhammad Taib, Kerry Lim, Dachuan Huang, Jing Quan Lim, Masatoshi Hazama, Koji Fukushima, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong, Jason Yongsheng Chan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7276.
https://doi.org/10.1158/1538-7445.AM2024-7276
Published: 22 March 2024
View article titled, Abstract 7276: Potent anti-proliferative activity of brincidofovir in Diffuse Large B-cell Lymphoma with overexpression of transcriptional repressor TLE1
Journal Articles

Abstract 7048: Multiomics characterization of breast angiosarcoma from an Asian cohort reveals enrichment for angiogenesis signaling pathway and tumor-infiltrating macrophages

Tun Kiat Ko, Zexi Guo, Bavani Kannan, Boon Yee Lim, Jing Yi Lee, Abner Herbert Lim, Zhimei Li, Elizabeth Chun Yong Lee, Cedric Chuan-Young Ng, Bin Tean Teh, Jason Yongsheng Chan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7048.
https://doi.org/10.1158/1538-7445.AM2024-7048
Published: 22 March 2024
View article titled, Abstract 7048: Multiomics characterization of breast angiosarcoma from an Asian cohort reveals enrichment for angiogenesis signaling pathway and tumor-infiltrating macrophages
Journal Articles

Abstract PR003: PBRM1-deficient PBAF complexes target aberrant genomic loci to activate NF-κB pathway in clear cell renal cell carcinoma

Xiaosai Yao, Jing Han Hong, Amrita Nargund, Michelle S.W. Ng, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2023) 83 (16_Supplement): PR003.
https://doi.org/10.1158/1538-7445.KIDNEY23-PR003
Published: 15 August 2023
View article titled, Abstract PR003: PBRM1-deficient PBAF complexes target aberrant genomic loci to activate NF-κB pathway in clear cell renal cell carcinoma
Journal Articles

Abstract 1494: PBRM1-deficient PBAF complexes target de novo genomic loci to activate NF-κB pathway in clear cell renal cell carcinoma

Xiaosai Yao, Jing Han Hong, Amrita Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, Robert Yauch, Kenneth Tou-En Chang, Radoslaw M. Sobota, Patrick Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1494.
https://doi.org/10.1158/1538-7445.AM2023-1494
Published: 04 April 2023
View article titled, Abstract 1494: PBRM1-deficient PBAF complexes target de novo genomic loci to activate NF-κB pathway in clear cell renal cell carcinoma
Journal Articles

Abstract 4458: Single cell landscape of multicentric Castleman disease in identical twins

Jason Yongsheng Chan, Jui Wan Loh, Jing Quan Lim, Herty Liany, Elizabeth Chun Yong Lee, Jing Yi Lee, Bavani Kannan, Boon Yee Lim, Kerry Lim, Jeslin Chian Hung Ha, Cedric Chuan-Young Ng, Tun Kiat Ko, Dachuan Huang, Dominique Yuan Bin Seow, Chee Leong Cheng, Sock Hoai Chan, Joanne Ngeow, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4458.
https://doi.org/10.1158/1538-7445.AM2023-4458
Published: 04 April 2023
View article titled, Abstract 4458: Single cell landscape of multicentric Castleman disease in identical twins
Journal Articles

Correction: Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer

Amrita M. Nargund, Chang Xu, Amit Mandoli, Atsushi Okabe, Gao Bin Chen, Kie Kyon Huang, Taotao Sheng, Xiaosai Yao, Jia Ming Nickolas Teo, Raghav Sundar, Yee Jiun Kok, Yi Xiang See, Manjie Xing, Zhimei Li, Chern Han Yong, Aparna Anand, Zul Fazreen Bin Adam Isa, Lai Fong Poon, Michelle Shu Wen Ng, Javier Yu Peng Koh, Wen Fong Ooi, Su Ting Tay, Xuewen Ong, Angie Lay Keng Tan, Duane T. Smoot, Hassan Ashktorab, Heike I. Grabsch, Melissa J. Fullwood, Bin Tean Teh, Xuezhi Bi, Atsushi Kaneda, Shang Li, Patrick Tan
Journal: Cancer Research
Cancer Res (2023) 83 (5): 804.
https://doi.org/10.1158/0008-5472.CAN-22-4060
Published: 02 March 2023
View article titled, Correction: Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer
Open the PDF for Correction: Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer in another window
Journal Articles

Abstract B006: PBRM1-deficient PBAF complexes target de novo genomic loci to activate NF-κB pathway in kidney cancer

Xiaosai Yao, Jing Han Hong, Amrita Nargund, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): B006.
https://doi.org/10.1158/1538-7445.CancEpi22-B006
Published: 01 December 2022
View article titled, Abstract B006: PBRM1-deficient PBAF complexes target de novo genomic loci to activate NF-κB pathway in kidney cancer
Journal Articles

Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer

Amrita M. Nargund, Chang Xu, Amit Mandoli, Atsushi Okabe, Gao Bin Chen, Kie Kyon Huang, Taotao Sheng, Xiaosai Yao, Jia Ming Nickolas Teo, Raghav Sundar, Yee Jiun Kok, Yi Xiang See, Manjie Xing, Zhimei Li, Chern Han Yong, Aparna Anand, Zul Fazreen Bin Adam Isa, Lai Fong Poon, Michelle Shu Wen Ng, Javier Yu Peng Koh, Wen Fong Ooi, Su Ting Tay, Xuewen Ong, Angie Lay Keng Tan, Duane T. Smoot, Hassan Ashktorab, Heike I. Grabsch, Melissa J. Fullwood, Bin Tean Teh, Xuezhi Bi, Atsushi Kaneda, Shang Li, Patrick Tan
Journal: Cancer Research
Cancer Res (2022) 82 (14): 2538–2551.
https://doi.org/10.1158/0008-5472.CAN-21-2072
Published: 18 July 2022
View article titled, Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer
Open the PDF for Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Targeting the IRAK1–S100A9 Axis Overcomes Resistance to Paclitaxel in Nasopharyngeal Carcinoma

Lizhen Liu, Sailan Liu, Peng Deng, Yujing Liang, Rong Xiao, Lin-Quan Tang, Jinghong Chen, Qiu-Yan Chen, Peiyong Guan, Shu-Mei Yan, Xiangliang Huang, Jing Han Hong, Jianfeng Chen, Yichen Sun, Bin Tean Teh, Qiang Yu, Hai-Qiang Mai, Jing Tan
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1413–1425.
https://doi.org/10.1158/0008-5472.CAN-20-2125
Published: 01 March 2021
View article titled, Targeting the IRAK1–S100A9 Axis Overcomes Resistance to Paclitaxel in Nasopharyngeal Carcinoma
Open the PDF for Targeting the IRAK1–S100A9 Axis Overcomes Resistance to Paclitaxel in Nasopharyngeal Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract PL02-04: Genomic and epigenomic studies of cholangiocarcinoma in diverse populations

Bin Tean Teh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): PL02-04.
https://doi.org/10.1158/1538-7445.AM2019-PL02-04
Published: 01 July 2019
View article titled, Abstract PL02-04: Genomic and epigenomic studies of cholangiocarcinoma in diverse populations
Journal Articles

Abstract 1832: Large variations in clinical and ethical aspects of genomic sequencing initiatives: A Global Alliance for Genomics and Health (GA4GH) survey

Jeremy Lewin, Daniel J. Vis, Mark Lawler, Rachel Liao, Mao Mao, Bin Tean Teh, William Sellers, Robyn Ward, Anamaria Aranha Camargo, Fabrice Andre, Richard Schilsky, Denis Lacombe, Tatsuhiro Shibata, Stephen Fox, Christophe Le Tourneau, William S. Dalton, Bartha Maria Knoppers, Charles Sawyers, Emile E. Voest, Lillian L. Siu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1832.
https://doi.org/10.1158/1538-7445.AM2016-1832
Published: 15 July 2016
View article titled, Abstract 1832: Large variations in clinical and ethical aspects of genomic sequencing initiatives: A Global Alliance for Genomics and Health (GA4GH) survey
Journal Articles

Abstract 3874: Mutational landscapes of oral tongue squamous cell carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

Andre L. Vettore, Kalpana Ramnarayanan, Choon Kiat Ong, Hui Sun Leong, Weng Khong Lim, Ioana Cutcutache, John R. Mcpherson, Shenli Zhang, Thankshayeni Skanthakumar, Daniel SW Tan, Bin Tean Teh, Steve Rozen, Patrick Tan, N Gopalakrishna Iyer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3874.
https://doi.org/10.1158/1538-7445.AM2015-3874
Published: 01 August 2015
View article titled, Abstract 3874: Mutational landscapes of oral tongue squamous cell carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance
Journal Articles

Abstract 5184: Distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers revealed by whole exome sequencing

Choon Kiat Ong, Waraporn Chan-on, Maarja-Liisa Nairismagi, Weng Khong Lim, Simona Dima, Chawalit Pairojkul, Paiboon Sithithaworn, Irinel Popescu, Steve Rozen, Patrick Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5184.
https://doi.org/10.1158/1538-7445.AM2014-5184
Published: 01 October 2014
View article titled, Abstract 5184: Distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers revealed by whole exome sequencing
Journal Articles

Abstract 4270: The use of mutational signatures in identifying carcinogen exposure

Song Ling Poon, See-Tong Pang, John R. McPherson, Steven G. Rozen, Patrick Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4270.
https://doi.org/10.1158/1538-7445.AM2014-4270
Published: 01 October 2014
View article titled, Abstract 4270: The use of mutational signatures in identifying carcinogen exposure
Journal Articles

Abstract A18: The role of histone demethylase JARID1C in tumorigenesis of clear cell renal cell carcinoma

Lian Dee Ler, George Edward Allen, Swe Swe Myint, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A18.
https://doi.org/10.1158/1538-7445.CEC13-A18
Published: 13 May 2014
View article titled, Abstract A18: The role of histone demethylase JARID1C in tumorigenesis of clear cell renal cell carcinoma
Journal Articles

Abstract 1200: Molecular subtypes of gastric cancer show systematic differences in response to PI3K inhibitors and fluorouracil.

Zengdeng Lei, Nian Tao Deng, Hermioni Zouridis, Iain Beehaut Tan, Chia Huey Ooi, Tatiana Ivanova, Shenli Zhang, Minghui Lee, Jeanie Wu, Anna Ngo, Sravanthy Manesh, Alex Boussioutas, Bin Tean Teh, Liang Kee Goh, Horst Flotow, Patrick Tan, Steven G. Rozen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1200.
https://doi.org/10.1158/1538-7445.AM2013-1200
Published: 15 April 2013
View article titled, Abstract 1200: Molecular subtypes of gastric cancer show systematic differences in response to PI3K inhibitors and fluorouracil.
Journal Articles

CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma

Aikseng Ooi, Karl Dykema, Asif Ansari, David Petillo, John Snider, Richard Kahnoski, John Anema, David Craig, John Carpten, Bin-Tean Teh, Kyle A. Furge
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2044–2051.
https://doi.org/10.1158/0008-5472.CAN-12-3227
Published: 02 April 2013
View article titled, <em>CUL3</em> and <em>NRF2</em> Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Open the PDF for <em>CUL3</em> and <em>NRF2</em> Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma

Bill Wondergem, Zhongfa Zhang, Dachuan Huang, Choon Kiat Ong, Julie Koeman, David Van't Hof, David Petillo, Aikseng Ooi, John Anema, Brian Lane, Richard J. Kahnoski, Kyle A. Furge, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2012) 72 (17): 4361–4371.
https://doi.org/10.1158/0008-5472.CAN-11-2330
Published: 30 August 2012
View article titled, Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma
Open the PDF for Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data