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Journal Articles

Abstract 2124: ATRA mediated inhibition of myeloid-derived suppressor cells overcomes resistance to immune checkpoint inhibition in murine models of LKB1-deficient non-small cell lung cancer

William P. Crosson, Rui Li, Ramin Salehi-Rad, Raymond J. Lim, Jensen W. Abascal, Bitta P. Kahangi, Edgar Perez Reyes, Camelia Dumitras, Zhe Jing, Kostyantyn Krysan, Linh M. Tran, Bin Liu, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2124.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2124
Published: 15 June 2022
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Journal Articles

Abstract 4206: In situ vaccination with CCL21-DC sensitizes non-responsive murine NSCLCs to anti-PD-1 therapy and generates systemic tumor-specific immune memory

Ramin Salehi-Rad, Raymond J. Lim, Linh M. Tran, Yushen Du, Camelia Dumitras, Tianhao Zhang, William Crosson, Jensen Abascal, Kostyantyn Krysan, Bin Liu, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4206.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4206
Published: 15 June 2022
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Journal Articles

Abstract 4208: In situ vaccination of non-small cell lung cancer with CXCL9/10-engineered dendritic cells combined with PD-1 blockade

Raymond J. Lim, Ramin Salehi-rad, Linh M. Tran, Camelia Dumitras, Jensen W. Abascal, William P. Crosson, Tejas S. Patel, Samantha Man, Rui Li, Kostyantyn Krysan, Bin Liu, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4208.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4208
Published: 15 June 2022
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Journal Articles

Abstract 4212: In situvaccination with Flt3l gene-modified CD103+type 1 conventional dendritic cells (cDC1) in murine models of non-small cell lung cancer (NSCLC)

Jensen W. Abascal, Raymond J. Lim, Ramin Salehi-Rad, Zhe Jing, William P. Crosson, Bitta P. Kahangi, Edgar Perez Reyes, Diana Reyimjan, Jessie Zhu, Linh M. Tran, Manash Paul, Kostyantyn Krysan, Bin Liu, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4212.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4212
Published: 15 June 2022
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Journal Articles

Abstract 5438: FCN-589, a novel, potent and selective BTK inhibitor, targets BTK C481S for the treatment of B-cell malignancies

Shu Lin, Haohan Tan, Qihong Liu, Yunling Wang, Bin Liu, Zhifu Li, Zhifang Chen, Xianlong Wang, Xingdong Zhao, Lihua Jiang, Xilei Wang, Tao Cheng, Jiashu Zhou, Weibo Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5438.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5438
Published: 15 June 2022
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Journal Articles

Abstract CT219: Phase I trial of in situ vaccination with autologous CCL21 gene-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced non-small cell lung cancer (NSCLC)

Bin Liu, Aaron Lisberg, Ramin Salehi-Rad, Jay Lee, Linh M. Tran, Kostyantyn Krysan, Raymond Lim, Camelia Dumitras, Zhe Jing, Michael Oh, Fereidoun Abtin, Robert Suh, Scott Genshaft, Scott Oh, Gregory Fishbein, Ciara M. O'Higgins, Anita Kaul, Kanwarpal Kahlon, Shahryar Ashouri, Jonathan Goldman, David Elashoff, Edward Garon, Steven Dubinett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT219.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT219
Published: 15 June 2022
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Journal Articles

Abstract 266: Differential collective cell migratory behaviors modulated by phospholipid nanoparticles

Kenry, Bin Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 266.
DOI: https://doi.org/10.1158/1538-7445.AM2021-266
Published: 01 July 2021
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Journal Articles

Abstract 2417: Mutant p53 and oncogenic KRAS converge on CREB1 to drive pancreatic cancer metastasis

Michael Paul Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra Allton, Tara Hughes, Christian Siangco, Jithesh Augustine, Yaan Kang, Joy M. McDaniel, Shunbin Xiong, Eugene Koay, Florencia McAllister, Christopher Bristow, Timothy Heffernan, Anirban Maitra, Bin Liu, Michelle Barton, Amanda Wasylischen, Jason Fleming, Guillermina lozano
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2417.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2417
Published: 01 July 2021
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Journal Articles

Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-Deficient Non–Small Cell Lung Cancer

Rui Li, Ramin Salehi-Rad, William Crosson, Milica Momcilovic, Raymond J. Lim, Stephanie L. Ong, Zi Ling Huang, Tianhao Zhang, Jensen Abascal, Camelia Dumitras, Zhe Jing, Stacy J. Park, Kostyantyn Krysan, David B. Shackelford, Linh M. Tran, Bin Liu, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2021) 81 (12): 3295–3308.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-3564
Published: 15 June 2021
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Includes: Supplementary data
Journal Articles

ALPPL2 Is a Highly Specific and Targetable Tumor Cell Surface Antigen

Yang Su, Xin Zhang, Scott Bidlingmaier, Christopher R. Behrens, Nam-Kyung Lee, Bin Liu
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4552–4564.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-1418
Published: 15 October 2020
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Includes: Supplementary data
Journal Articles

Abstract 1016: Inhibition of chemokine-induced myeloid cells potentiates the anti-PD-1 response in KRAS/LKB1 mutant non-small cell lung cancer

Rui Li, Ramin Salehi-Rad, Milica Momcilovic, Stephanie Ong, Raymond Lim, Zi Ling Huang, Linh Tran, Zhe Jing, Manash Paul, Michael Teitell, John Minna, David Shackelford, Krysan Kostyantyn, Bin Liu, Steven Dubinett
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1016.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1016
Published: 15 August 2020
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Journal Articles

Abstract LB-109: Discovery of a highly potent and blood-brain barrier (BBB) penetrable second generation Pan-TRK/ROS1 dual inhibitor, XZP-5955

Jun Sun, Shujin Bai, Bo Chen, Yuqi Dong, Yanwei Ding, Qian Hu, Xifeng Ma, Yanfang Nie, Chunmin Shi, Ying Sun, Zhaoqiang Wei, Xiping Yang, Peng Zhu, Chengkong Shi, Jiakui Li, Chongtie Shi, Zuliang Yao, Bin Liu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-109.
DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-109
Published: 15 August 2020
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Journal Articles

Abstract 5374: Rapid microfluidic isolation and detection of circulating tumor cells/clusters with zero sample preparation

Jian Zhou, Bin Liu, Qiyue Luan, Apurva Mallisetty, Alicia Hulbert, Ian Papautsky
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5374.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5374
Published: 15 August 2020
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Journal Articles

Abstract 539: A bispecific Fc-silenced IgG1 antibody (MCLA-145) requires PD-L1 binding to activate CD137

Patrick Mayes, Paul Tacken, Steve Wang, Pieter-Fokko van Loo, Thomas Condamine, Hans van der Maaden, Eric Rovers, Steef Engels, Floris Fransen, Ashwini Kulkarni, Yao-bin Liu, Arpita Mondal, Leslie Hall, Soyeon Kim, Marina Martinez, Shaun O'Brien, Edmund Moon, Steven Albelda, Peggy Scherle, Gregory Hollis, Reid Huber, Mark Throsby, Cecile A. Geuijen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 539.
DOI: https://doi.org/10.1158/1538-7445.AM2019-539
Published: 01 July 2019
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Journal Articles

Abstract CT226: A Phase I trial of in situ vaccination with autologous CCL21-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced NSCLC

Bin Liu, Edward B. Garon, Aaron E. Lisberg, Ramin Salehi-Rad, Jay M. Lee, Linh M. Tran, Kostyantyn Krysan, Rui Li, Raymond J. Lim, Manash Paul, Ying Lin, Zhe Jing, Fereidoun Abtin, Robert D. Suh, Scott Oh, Denise R. Aberle, Lauren E. Winter, William Dean Wallace, David Elashoff, Sherven Sharma, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT226.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT226
Published: 01 July 2019
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Journal Articles

Abstract 3214: In situ vaccination with CCL21-modified dendritic cells (CCL21-DC) combined with checkpoint blockade in murine models of NSCLC

Raymond J. Lim, Ramin Salehirad, Bin Liu, Rui Li, Linh M. Tran, Kostyantyn Krysan, Stephanie Ong, Zi L. Huang, David B. Shackelford, Sherven Sharma, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3214.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3214
Published: 01 July 2019
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Journal Articles

Abstract 1316: Preclinical evaluation of TUL-001, an EGFR inhibitor for the treatment of NSCLC with brain metastasis (BM)

Xile Liu, Liwei Mu, Bin Liu, Shouting Wu, Degang Wang, Lu Zhang, Charles Z Ding, Lihong Hu, Weifeng Mao, Zhenzhen Zhu, Chen Chen, Yuanfeng Xia, Chichung Chan, Shuhui Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1316.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1316
Published: 01 July 2019
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Journal Articles

Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer

Nicole M. Kettner, Smruthi Vijayaraghavan, Merih Guray Durak, Tuyen Bui, Mehrnoosh Kohansal, Min Jin Ha, Bin Liu, Xiayu Rao, Jing Yang, Min Yi, Jason P. Carey, Xian Chen, T. Kris Eckols, Akshara S. Raghavendra, Nuhad K. Ibrahim, Meghan Karuturi, Stephanie S. Watowich, Aysegul A. Sahin, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 323.
DOI: https://doi.org/10.1158/1538-7445.AM2019-323
Published: 01 July 2019
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Abstract 2710: Depletion of CXCR2-dependent myeloid-derived suppressor cells (MDSCs) overcomes anti-PD-1 resistance in a murine model of LKB1-deficient non-small cell lung cancer (NSCLC) with high mutational load

Rui Li, Ramin Salehi-Rad, Stephanie Ong, Milica Momcilovic, Bin Liu, Raymond Lim, Linh Tran, Ziling Huang, Zhe Jing, Manash Paul, Kostyantyn Krysan, Stacy Park, John Minna, Michael Teitell, David Shackelford, Steven Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2710.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2710
Published: 01 July 2019
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Journal Articles

Abstract 4391: Disruption of the translation initiation complex by eIF4A mutant inhibits prostate tumor growth in vivo

Puja Singh, Hanyong Chen, Hanxuan Li, Young-In Chi, Bin Liu, Junxuan Lu, Wei Li, Zigang Dong, Yibin Deng
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4391.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4391
Published: 01 July 2019
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