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Journal Articles

Abstract 4230: Patient-derived tumoroid platforms with progressing tumor microenvironment representability reveals efficacy and resistance patterns in pre-clinical HSP90i regimen testing for improved clinical insights

Huckie Del Mundo, Damieanus O. Ochola, Bhuvanesh Dave, Preethi Samuel
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4230.
https://doi.org/10.1158/1538-7445.AM2024-4230
Published: 22 March 2024
View article titled, Abstract 4230: Patient-derived tumoroid platforms with progressing tumor microenvironment representability reveals efficacy and resistance patterns in pre-clinical HSP90i regimen testing for improved clinical insights
Journal Articles

Abstract 4216: Indication agnostic evaluation of CAR T cell function using patient-derived immunocompetent tumoroid modelling platform

Damieanus O. Ochola, Huckie Dell Mundo, Preethi Samuel, Natalia Korkorina, Bhuvanesh Dave
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4216.
https://doi.org/10.1158/1538-7445.AM2024-4216
Published: 22 March 2024
View article titled, Abstract 4216: Indication agnostic evaluation of CAR T cell function using patient-derived immunocompetent tumoroid modelling platform
Journal Articles

Abstract 6779: Modality agnostic tumor models of cancer which can more accurately define drug efficacy and mechanism to help develop more effective therapeutics

Preethi Samuel, Damieanus Odour Ochola, Huckie Del Mundo, Bhuvanesh Dave
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6779.
https://doi.org/10.1158/1538-7445.AM2024-6779
Published: 22 March 2024
View article titled, Abstract 6779: Modality agnostic tumor models of cancer which can more accurately define drug efficacy and mechanism to help develop more effective therapeutics
Journal Articles

Abstract 3441: A RPL39-SGK3 signaling pathway that may play a key role in breast cancer therapy resistance

Dan Liu, Bhuvanesh Dave
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3441.
https://doi.org/10.1158/1538-7445.AM2019-3441
Published: 01 July 2019
View article titled, Abstract 3441: A RPL39-SGK3 signaling pathway that may play a key role in breast cancer therapy resistance
Journal Articles

Abstract LB-196: Evaluation of anti PD-1 plus nitric oxide synthase inhibition combination therapy in 12 triple-negative breast cancer patient-derived xenografts using a human-derived immune system model

Daniel Davila-Gonzalez, Roberto R. Rosato, Wei Qian, Antony J. Kozielski, Wen Chen, Dong S. Choi, Bhuvanesh Dave, Dinko Kranjac, Joe E. Ensor, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-196.
https://doi.org/10.1158/1538-7445.AM2017-LB-196
Published: 01 July 2017
View article titled, Abstract LB-196: Evaluation of anti PD-1 plus nitric oxide synthase inhibition combination therapy in 12 triple-negative breast cancer patient-derived xenografts using a human-derived immune system model
Journal Articles

Abstract 518: Ionizing radiation-induced DNA damage response decreases during induced pluripotent and embryonic stem cell differentiation

Kalpana Mujoo, Raj K. Pandita, Anjana Tiwari, Vijay Charaka, Walter N. Hittelman, Murlidhar Hegde, Haibo Wang, Clayton R. Hunt, Bhuvanesh Dave, Jenny Chang, E Brian Butler, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 518.
https://doi.org/10.1158/1538-7445.AM2016-518
Published: 15 July 2016
View article titled, Abstract 518: Ionizing radiation-induced DNA damage response decreases during induced pluripotent and embryonic stem cell differentiation
Journal Articles

Abstract 2539: Targeting therapy-resistant gastric and esophageal cancers with mTOR ATP site inhibitors

Bhuvanesh Dave, Alexandria Phan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2539.
https://doi.org/10.1158/1538-7445.AM2015-2539
Published: 01 August 2015
View article titled, Abstract 2539: Targeting therapy-resistant gastric and esophageal cancers with mTOR ATP site inhibitors
Journal Articles

Abstract 2248: Mechanism of action of RPL39 in breast cancer initiation and metastasis

Bhuvanesh Dave, Jenny Chang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2248.
https://doi.org/10.1158/1538-7445.AM2015-2248
Published: 01 August 2015
View article titled, Abstract 2248: Mechanism of action of RPL39 in breast cancer initiation and metastasis
Journal Articles

Abstract 2312: Identifying novel cancer stem cell target for triple-negative breast cancer

Yi Liu, Dong Soon Choi, Sergio Grandos-Principal, Wei Qian, Lacey Burey, Helen Wong, Crisitian Rodriguez-Aguayo, Anil Sood, Zheng Li, Stephen Wong, Heidi Weiss, Bhuvanesh Dave, Melissa Landis, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2312.
https://doi.org/10.1158/1538-7445.AM2015-2312
Published: 01 August 2015
View article titled, Abstract 2312: Identifying novel cancer stem cell target for triple-negative breast cancer
Journal Articles

Abstract 4024: iNOS inhibition increases survival in triple negative breast cancer by targeting metastasis and epithelial-mesenchymal transition

Sergio M. Granados, Yi Liu, Bhuvanesh Dave, Melissa D. Landis, Steven S. Gross, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4024.
https://doi.org/10.1158/1538-7445.AM2014-4024
Published: 01 October 2014
View article titled, Abstract 4024: iNOS inhibition increases survival in triple negative breast cancer by targeting metastasis and epithelial-mesenchymal transition
Journal Articles

Abstract 237: Chloroquine inhibits cancer stem cells in triple negative breast cancer via regulation of DNA methylation.

Dong Soon Choi, Elvin Blanco, Sergio M. Granados-Principal, Bhuvanesh Dave, Melissa Landis, Helen Wong, Jenny Chang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 237.
https://doi.org/10.1158/1538-7445.AM2013-237
Published: 15 April 2013
View article titled, Abstract 237: Chloroquine inhibits cancer stem cells in triple negative breast cancer via regulation of DNA methylation.
Journal Articles

Abstract 3768: Autophagy: a mechanism of resistance to therapy in breast cancer.

Bhuvanesh Dave, Sucharita Mitra
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3768.
https://doi.org/10.1158/1538-7445.AM2013-3768
Published: 15 April 2013
View article titled, Abstract 3768: Autophagy: a mechanism of resistance to therapy in breast cancer.
Journal Articles

Abstract 2712: Identification of tumor initiating genes RPL39 and MLF2 that mediate lung metastasis through nitric oxide signaling and mesenchymal to epithelial transition.

Bhuvanesh Dave, Sergio Granados, Junhua Mai, Dong Soon Choi, Ding Cheng Gao, Sucharita Mitra, Haifa Shen, Senthil Muthuswamy, Vivek Mittal, Mauro Ferrari, Jenny Chang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2712.
https://doi.org/10.1158/1538-7445.AM2013-2712
Published: 15 April 2013
View article titled, Abstract 2712: Identification of tumor initiating genes RPL39 and MLF2 that mediate lung metastasis through nitric oxide signaling and mesenchymal to epithelial transition.
Journal Articles

Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors

Anindita Chakrabarty, Neil E. Bhola, Cammie Sutton, Ritwik Ghosh, María Gabriela Kuba, Bhuvanesh Dave, Jenny C. Chang, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1190–1200.
https://doi.org/10.1158/0008-5472.CAN-12-2440
Published: 31 January 2013
View article titled, Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Open the PDF for Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors in another window
Includes: Supplementary data
Journal Articles

Abstract 231: Upregulation of HER3 (ErbB3) levels and function counteracts the antitumor effect of HER2 and PI3K inhibitors

Joan Garrett, Cammie Rinehart, Anindita Chakrabarty, Bhuvanesh Dave, William Pao, Charles Manning, Jenny Chang, Carlos Arteaga
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 231.
https://doi.org/10.1158/1538-7445.AM2011-231
Published: 15 April 2011
View article titled, Abstract 231: Upregulation of HER3 (ErbB3) levels and function counteracts the antitumor effect of HER2 and PI3K inhibitors
Journal Articles

Abstract LB-110: Bioinformatic discovery of repositioned drugs to target breast tumor initiating cells

Bhuvanesh Dave, Hong Zhao, Linda T. Vahdat, Jenny C. Chang, Stephen TC Wong
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-110.
https://doi.org/10.1158/1538-7445.AM2011-LB-110
Published: 15 April 2011
View article titled, Abstract LB-110: Bioinformatic discovery of repositioned drugs to target breast tumor initiating cells
Journal Articles

Abstract 4213: Lentiviral shRNA screen testing a gene signature of breast cancer stem cells using high throughput mammosphere assays

Bhuvanesh Dave, Michael T. Lewis, Jenny CN Chang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4213.
https://doi.org/10.1158/1538-7445.AM10-4213
Published: 15 April 2010
View article titled, Abstract 4213: Lentiviral shRNA screen testing a gene signature of breast cancer stem cells using high throughput mammosphere assays
Journal Articles

Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway

Judy S. Crabtree, Scott A. Jelinsky, Heather A. Harris, Sung E. Choe, Monette M. Cotreau, Michelle L. Kimberland, Ewa Wilson, Kathryn A. Saraf, Wei Liu, Adrienne S. McCampbell, Bhuvanesh Dave, Russell R. Broaddus, Eugene L. Brown, Wenling Kao, Jerauld S. Skotnicki, Magid Abou-Gharbia, Richard C. Winneker, Cheryl L. Walker
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6171–6178.
https://doi.org/10.1158/0008-5472.CAN-08-4471
Published: 29 July 2009
View article titled, Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Open the PDF for Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway in another window
Includes: Supplementary data
Journal Articles

Activation of mTOR signaling and loss of negative feedback to IRS1 are early events in development of endometrial hyperplasia in Tsc2-deficient rats

Adrienne McCampbell, Cheryl Walker, Bhuvanesh Dave, Russell Broaddus
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3563.
Published: 01 May 2008
View article titled, Activation of mTOR signaling and loss of negative feedback to IRS1 are early events in development of endometrial hyperplasia in Tsc2-deficient rats
Journal Articles

Enhanced Progesterone Receptor A expression by dietary soy in a hormone-dependent (NMU) model of rat mammary carcinogenesis: implications for tumor progression.

Bhuvanesh Dave, Renea R. Eason, S. Renee Till, Soheila Korourian, Rosalia Cm Simmen
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1312.
Published: 15 April 2006
View article titled, Enhanced Progesterone Receptor A expression by dietary soy in a hormone-dependent (NMU) model of rat mammary carcinogenesis: implications for tumor progression.