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Journal Articles

Abstract 2582: Silencing MICAL2 expression in pancreatic cancer cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and sensitizes tumors to immune checkpoint blockade therapy

Free
Bharti Garg, Evangeline S. Mose, Edgar Esparaze, Jay Patel, Rithika Medari, Sarah Sass, Alexei Martsinkovskiy, Asmina Courelli, Gisselle Gonzalez, Adam Engler, Parag Katira, Herve Tiriac, Andrew Lowy
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2582.
https://doi.org/10.1158/1538-7445.AM2025-2582
Published: 21 April 2025
View articletitled, Abstract 2582: Silencing MICAL2 expression in pancreatic cancer cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and sensitizes tumors to immune checkpoint blockade therapy
Journal Articles

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Open Access
Bharti Garg, Sohini Khan, Asimina S. Courelli, Ponmathi Panneerpandian, Deepa Sheik Pran Babu, Evangeline S. Mose, Kevin Christian Montecillo Gulay, Shweta Sharma, Divya Sood, Alexander T. Wenzel, Alexei Martsinkovskiy, Nirakar Rajbhandari, Jay Patel, Dawn Jaquish, Edgar Esparza, Katelin Jaque, Neetu Aggarwal, Guillem Lambies, Anthony D’Ippolito, Kathryn Austgen, Brian Johnston, David A. Orlando, Gun Ho Jang, Steven Gallinger, Elliot Goodfellow, Pnina Brodt, Cosimo Commisso, Pablo Tamayo, Jill P. Mesirov, Hervé Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1049–1063.
https://doi.org/10.1158/0008-5472.CAN-24-0744
Published: 14 March 2025
View articletitled, MICAL2 Promotes Pancreatic Cancer Growth and Metastasis
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Includes: Supplementary data
Journal Articles

Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy

Free
Bharti Garg, Evangeline Mose, Edgar Esparaza, Jay Patel, Rithika Medari, Alexei Martsinkovskiy, Carrie Bishop, Gissele Gonzalez, Adam Engler, Parag Katira, Herve Tiriac, Andrew M Lowy
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A052.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A052
Published: 15 September 2024
View articletitled, Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy
Journal Articles

Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism

Free
Bharti Garg, EvanGeline Mose, Edgar Esparza, Jay Patel, Sarah Sass, Alexei Martsinkovskiy, Dawn Jacquish, Herve Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A039.
https://doi.org/10.1158/1538-7445.PANCA2023-A039
Published: 16 January 2024
View articletitled, Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism
Journal Articles

Abstract 1328: Building a 3D co-culture model for metastatic pancreatic ductal cancer using Curiochips microphysiological system

Free
Sumin Kim, Yeongmin Choi, Jihye Baek, Bharti Garg, Jan Pencik, Andrew M. Lowy, Herve Tiriac, Sanghee Yoo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1328.
https://doi.org/10.1158/1538-7445.AM2023-1328
Published: 04 April 2023
View articletitled, Abstract 1328: Building a 3D co-culture model for metastatic pancreatic ductal cancer using Curiochips microphysiological system
Journal Articles

Abstract C044: MICAL2 expression in pancreatic cancer cells modulates the tumor microenvironment through the TGF beta pathway

Free
Bharti Garg, Shweta Sharma, Sohini Khan, Edgar Esparza, Sarah Sass, Dawn Jacquish, Evangeline Mose, Herve Tiriac, Andrew Lowy
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C044.
https://doi.org/10.1158/1538-7445.PANCA22-C044
Published: 15 November 2022
View articletitled, Abstract C044: MICAL2 expression in pancreatic cancer cells modulates the tumor microenvironment through the TGF beta pathway
Journal Articles

Abstract B017: MICAL2 promotes pancreatic cancer growth and metastasis independent of MRTF-A signaling

Free
Sohini Khan, Shweta Sharma, Divya Sood, Bharti Garg, Dawn Jaquish, Evangeline Mose, Edgar Esparza, Herve Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): B017.
https://doi.org/10.1158/1538-7445.PANCA22-B017
Published: 15 November 2022
View articletitled, Abstract B017: MICAL2 promotes pancreatic cancer growth and metastasis independent of MRTF-A signaling
Journal Articles

Abstract PO-110: Targeting cathepsin B in the pancreatic stellate cells stimulates CD8+ T cell dependent anti-tumor immune response

Free
Bharti Garg, Tejeshwar Jain, Utpreksha Vaish, Vikas Dudeja
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-110.
https://doi.org/10.1158/1538-7445.PANCA21-PO-110
Published: 15 November 2021
View articletitled, Abstract PO-110: Targeting cathepsin B in the pancreatic stellate cells stimulates CD8+ T cell dependent anti-tumor immune response
Journal Articles

Abstract 4502: Cxcl-12-cxcr4 inhibition enhances immune response in pancreatic ductal adenocarcinoma

Free
Bharti Garg, Anthony Ferrantella, Bhuwan Giri, Shrey Modi, Vrisketan Sethi, Saba Kurtom, Sulagna Banerjee, Ramakrishnan Sundaram, Eli Gilboa, Ashok Saluja, Vikas Dudeja
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4502.
https://doi.org/10.1158/1538-7445.AM2018-4502
Published: 01 July 2018
View articletitled, Abstract 4502: Cxcl-12-cxcr4 inhibition enhances immune response in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 5127: Eradication of the gut microbiota reduces cancer burden in multiple models by modulating the immune system

Free
Vrishketan Sethi, Saba Kurtom, Mohd Tarique, Bhuwan Giri, Bharti Garg, Shweta Lavania, Anthony Ferrantella, Zoe Malchiodi, Leonor Hellmund, Harrys Charles Jacob, Rajinder Dawra, Sulagna Banerjee, Sabita Roy, Sundaram Ramakrishnan, Ashok Saluja, Vikas Dudeja
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5127.
https://doi.org/10.1158/1538-7445.AM2018-5127
Published: 01 July 2018
View articletitled, Abstract 5127: Eradication of the gut microbiota reduces cancer burden in multiple models by modulating the immune system