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Beverly A. Mock
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Journal Articles

Abstract 5113: A flexible pipeline for precision medicine biomarker detection and prediction of treatment response

Free
V Keith Hughitt, Sayeh Gorjifard, Aleksandra M. Michalowski, John K. Simmons, Ryan Dale, Eric C. Polley, Jonathan J. Keats, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5113.
https://doi.org/10.1158/1538-7445.AM2019-5113
Published: 01 July 2019
View articletitled, Abstract 5113: A flexible pipeline for precision medicine biomarker detection and prediction of treatment response
Journal Articles

Abstract 194: Effective targeting of MYC expression with a novel nucleic acid binding (G4-quadruplex) small molecule coupled with HDAC inhibition synergizes to limit myeloma growth

Free
Snehal M. Gaikwad, David R. Calabrese, Elena C. Leon, John K. Simmons, Shuling Zhang, Aleksandra Michalowski, Sayeh Gorjifard, Zaw Phyo, Daniel Connors, John S. Schneekloth, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 194.
https://doi.org/10.1158/1538-7445.AM2017-194
Published: 01 July 2017
View articletitled, Abstract 194: Effective targeting of MYC expression with a novel nucleic acid binding (G4-quadruplex) small molecule coupled with HDAC inhibition synergizes to limit myeloma growth
Journal Articles

Abstract 322: Selective inhibition of MYC expression by a small molecule G-quadruplex stabilizer

Free
Elena C. Leon, John K. Simmons, David Calabrese, Wendy DuBois, Kenneth Felsenstein, Lindsey B. Saunders, Shuling Zhang, Aleksandra Michalowski, Frank Gonzalez, Beverly A. Mock, John S. Schneekloth
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 322.
https://doi.org/10.1158/1538-7445.AM2016-322
Published: 15 July 2016
View articletitled, Abstract 322: Selective inhibition of MYC expression by a small molecule G-quadruplex stabilizer
Journal Articles

Abstract 2833: Genetic and pharmacologic inhibition of mTOR delays mortality due to thymc lymphoma formation in mice and is associated with decreases in cell cycle proteins

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Shuling Zhang, Joy M. Gary, John K. Simmons, Jinfei Xu, Benjamin J. Gamache, Ke Zhang, Nicholas Watson, Alexander L. Kovalchuk, Aleksandra M. Michalowski, Jin-Qiu Chen, Michelle A. Herrmann, Tuddow Thaiwong, Matti Kiupel, Wendy Dubois, Joseph R. Testa, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2833.
https://doi.org/10.1158/1538-7445.AM2016-2833
Published: 15 July 2016
View articletitled, Abstract 2833: Genetic and pharmacologic inhibition of mTOR delays mortality due to thymc lymphoma formation in mice and is associated with decreases in cell cycle proteins
Journal Articles

Abstract 2309: Murine model of dual mTORC kinase inhibition identifies CDK6 as a synergistic target in T-ALL

Free
Joy M. Gary, Jinfei Xu, John Simmons, Shuling Zhang, Benjamin Gamache, Ke Zhang, Alexander Kovalchuk, Aleksandra Michalowski, Jin-Qiu Chen, Michelle Herrmann, Wendy Dubois, Joseph Testa, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2309.
https://doi.org/10.1158/1538-7445.AM2015-2309
Published: 01 August 2015
View articletitled, Abstract 2309: Murine model of dual mTORC kinase inhibition identifies CDK6 as a synergistic target in T-ALL
Journal Articles

Abstract A73: De-convoluting therapeutic resistance in a pancreatic cancer model: Pharmacogenomic evaluation of intratumoral clonal heterogeneity

Free
Eveline E. Vietsch, John K. Simmons, Ivana Peran, Marianne Stenstra, Beverly A. Mock, Anton Wellstein
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A73.
https://doi.org/10.1158/1538-7445.PANCA2014-A73
Published: 30 June 2015
View articletitled, Abstract A73: De-convoluting therapeutic resistance in a pancreatic cancer model: Pharmacogenomic evaluation of intratumoral clonal heterogeneity
Journal Articles

Abstract PR6: A cooperative molecular response to combined mTOR/HDAC inhibition revealed by transcriptional co-expression analysis

Free
John Kyle Simmons, Beverly A. Mock, Aleksandra Michalowski, Jyoti Patel, Bih-Rong Wei, R. Mark Simpson, W. Michael Kuehl, Shuling Zhang, Ke Zhang, Ola Landgren
Journal: Cancer Research
Cancer Res (2012) 72 (13_Supplement): PR6.
https://doi.org/10.1158/1538-7445.CSB12-PR6
Published: 06 November 2014
View articletitled, Abstract PR6: A cooperative molecular response to combined mTOR/HDAC inhibition revealed by transcriptional co-expression analysis
Journal Articles

Abstract 1629: Identification and biological characterization of a novel class of small molecules to inhibit c-myc transcription

Free
Kenneth M. Felsenstein, John K. Simmons, Peter Gareiss, Beverly A. Mock, John ‘Jay’ S. Schneekloth
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1629.
https://doi.org/10.1158/1538-7445.AM2014-1629
Published: 01 October 2014
View articletitled, Abstract 1629: Identification and biological characterization of a novel class of small molecules to inhibit c-myc transcription
Journal Articles

Abstract 2217: A systems pharmacogenomic approach to identify synergistic molecular mechanisms of combined mTOR/HDAC inhibition.

Free
John K. Simmons, Aleksandra M. Michalowski, Ben Gamache, Jyoti Patel, Adriana Zingone, Ke Zhang, Michael Kuehl, Jing Huang, Ola Landgren, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2217.
https://doi.org/10.1158/1538-7445.AM2013-2217
Published: 15 April 2013
View articletitled, Abstract 2217: A systems pharmacogenomic approach to identify synergistic molecular mechanisms of combined mTOR/HDAC inhibition.
Journal Articles

Abstract 4734: Genes cooperatively downregulated by combined mTOR/histone deactylase (HDAC) inhibition are overexpressed in myeloma patients with lower survival

Free
Aleksandra M. Michalowski, John K. Simmons, Jyoti Patel, W Michael Kuehl, Shuling Zhang, Ola Landgren, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4734.
https://doi.org/10.1158/1538-7445.AM2012-4734
Published: 15 April 2012
View articletitled, Abstract 4734: Genes cooperatively downregulated by combined mTOR/histone deactylase (HDAC) inhibition are overexpressed in myeloma patients with lower survival
Journal Articles

Abstract 805: mTORC protein levels affect class switch recombination, somatic hypermutation, and antibody production

Free
Shuling Zhang, Margaret Pruitt, Dena Tran, Wendy DuBois, Richard Robinson, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 805.
https://doi.org/10.1158/1538-7445.AM2011-805
Published: 15 April 2011
View articletitled, Abstract 805: mTORC protein levels affect class switch recombination, somatic hypermutation, and antibody production
Journal Articles

Abstract 5310: mTOR knock-down mice exhibit altered T and B cell activation, differentiation and immune response

Free
Shuling Zhang, Julie Readinger, Laura Roth, Maggie Pruitt, Richard Robinson, Wendy DuBois, Val Bliskovsky, Ke Zhang, Julie Wu, Lino Tessarollo, Pam Schwartzberg, Beverly A. Mock
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5310.
https://doi.org/10.1158/1538-7445.AM10-5310
Published: 15 April 2010
View articletitled, Abstract 5310: mTOR knock-down mice exhibit altered T and B cell activation, differentiation and immune response
Journal Articles

Novel synthetic triterpenoid, CDDO-Imidazole, induces growth arrest and apoptosis in cell lines derived from new transgenic mouse model of human Burkitt lymphoma t(8;14)(q24;q32)

Free
Seung-Tae Chung, Seong-Su Han, Liangping Peng, Kyung-Sik Yoon, Michael B. Sporn, Beverly A. Mock, Siegfried Janz
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 319–320.
Published: 01 April 2004
View articletitled, Novel synthetic triterpenoid, CDDO-Imidazole, induces growth arrest and apoptosis in cell lines derived from new transgenic mouse model of human Burkitt lymphoma t(8;14)(q24;q32)
Journal Articles

Nonrandom Chromosomal Change (Trisomy 11) in Murine Plasmacytomas Induced by an ABL-MYC Retrovirus

Free
Francis Wiener, Allen Coleman, Beverly A. Mock, Michael Potter
Journal: Cancer Research
Cancer Res (1995) 55 (5): 1181–1188.
Published: 01 March 1995
View articletitled, Nonrandom Chromosomal Change (Trisomy 11) in Murine Plasmacytomas Induced by an ABL-MYC Retrovirus
Open the PDF for Nonrandom Chromosomal Change (Trisomy 11) in Murine Plasmacytomas Induced by an ABL-MYC Retrovirus in another window
Journal Articles

Identification of Two Genes on Chromosome 4 that Determine Resistance to Plasmacytoma Induction in Mice

Free
Michael Potter, Elizabeth B. Mushinski, Judith S. Wax, Janet Hartley, Beverly A. Mock
Journal: Cancer Research
Cancer Res (1994) 54 (4): 969–975.
Published: 01 February 1994
View articletitled, Identification of Two Genes on Chromosome 4 that Determine Resistance to Plasmacytoma Induction in Mice
Open the PDF for Identification of Two Genes on Chromosome 4 that Determine Resistance to Plasmacytoma Induction in Mice in another window