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Journal Articles

Abstract 2198: Exome and transcriptome sequencing of human tumors and tumor-derived cell lines

Michael L. Nickerson, Kate McGee, Bert Gold, Cindy Lawley, Bao Tran, Claudia Stewart, Tim Harkins, Fred Waldman, Berton Zbar, Lee Moore, Mike Dean
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2198.
https://doi.org/10.1158/1538-7445.AM10-2198
Published: 15 April 2010
View article titled, Abstract 2198: Exome and transcriptome sequencing of human tumors and tumor-derived cell lines
Journal Articles

Abstract #1018: VHL gene alteration and histopathologic risk factors in a large RCC case-control study

Lee Moore, Paul Brennan, Michael Nickerson, Erich Jaeger, Jessica Rinsky, David Zaridze, Vladimir Janout, Hellen Kollarova, Vladimir Bencko, Ivana Holcatova, Marie Navratilova, Neonilia Szesznenia-Dabrowska, Dana Mates, Laura Schmidt, Jorge Toro, Marston Linehan, Maria Merino, Berton Zbar, Paolo Boffetta, Wong-Ho Chow, Frederick Waldman, Nathaniel Rothman
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1018.
Published: 01 May 2009
View article titled, Abstract #1018: VHL gene alteration and histopathologic risk factors in a large RCC case-control study
Journal Articles

Restoration of the BHD gene suppresses tumorigenesis of BHD patient-derived renal cancer cells: implication of the involvement of the BHD gene in TGF-beta/BMP signaling

Seung-Beom Hong, Masaya Baba, Jaime Stull, Berton Zbar, W. Marston Linehan, Laura Schmidt
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2987.
Published: 01 May 2008
View article titled, Restoration of the BHD gene suppresses tumorigenesis of BHD patient-derived renal cancer cells: implication of the involvement of the BHD gene in TGF-beta/BMP signaling
Journal Articles

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Jennifer S. Isaacs, Yun Jin Jung, David Mole, Sunmin Lee, Carlos Torres-Cabala, Maria Marino, Jane Trepel, Berton Zbar, Jorge Toro, Peter Ratcliffe, Marston Linehan, Len Neckers
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 610.
Published: 01 May 2005
View article titled, HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
Journal Articles

Mitotic arrest and cellular senescence by the acute inactivation of the VHL gene

Seung-Beom Hong, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1048.
Published: 01 May 2005
View article titled, Mitotic arrest and cellular senescence by the acute inactivation of the <em>VHL</em> gene
Journal Articles

Mutations in the fumarate hydratase causes hereditary leiomyomatosis and renal cell carcinoma in families in North America.

Ming Wei, Carlos Torres-Cabala, Michael Nickerson, Gladys Glenn, Maria Turner, W. M. Linehan, Maria Merino, Laura Schmidt, Berton Zbar, Jorge R. Toro
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 524.
Published: 01 April 2004
View article titled, Mutations in the fumarate hydratase causes hereditary leiomyomatosis and renal cell carcinoma in families in North America.
Journal Articles

Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues

Michelle B. Warren, Carlos A. Torres-Cabalas, Maria L. Turner, Maria J. Merino, Vera Matrosova, Michael L. Nickerson, W. Marston Linehan, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 988.
Published: 01 April 2004
View article titled, Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues
Journal Articles

Conditional inactivation of the VHL gene during mouse embryo development

Seung-Beom Hong, Mutsuo Furihata, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1178.
Published: 01 April 2004
View article titled, Conditional inactivation of the <em>VHL</em> gene during mouse embryo development
Journal Articles

Familial renal carcinoma (FRC): Recruitment of families with multiple members affected with renal cancer

Berton Zbar, Laura S. Schmidt, Shyla Hale, Gregory W. Maher, Maria J. Merino, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 304.
Published: 01 April 2004
View article titled, Familial renal carcinoma (FRC): Recruitment of families with multiple members affected with renal cancer
Journal Articles

Hepatic Vascular Tumors, Angiectasis in Multiple Organs, and Impaired Spermatogenesis in Mice with Conditional Inactivation of the VHL Gene

Wenbin Ma, Lino Tessarollo, Seung-Beom Hong, Masaya Baba, Eileen Southon, Timothy C. Back, Sally Spence, Corrinne G. Lobe, Nirmala Sharma, Gregory W. Maher, Svetlana Pack, Alexander O. Vortmeyer, Chuanfa Guo, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5320–5328.
Published: 18 September 2003
View article titled, Hepatic Vascular Tumors, Angiectasis in Multiple Organs, and Impaired Spermatogenesis in Mice with Conditional Inactivation of the <em>VHL</em> Gene
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Includes: Supplementary data
Journal Articles

Constitutional von Hippel-Lindau (VHL) Gene Deletions Detected in VHL Families by Fluorescence in Situ Hybridization

Svetlana D. Pack, Berton Zbar, Evgenia Pak, David O. Ault, Jeffrey S. Humphrey, Thu Pham, Kathy Hurley, Robert J. Weil, Won-Sang Park, Igor Kuzmin, Catherine Stolle, Gladys Glenn, Lance A. Liotta, Michael I. Lerman, Richard D., Klausner W., Marston Linehan, Zhengping Zhuang
Journal: Cancer Research
Cancer Res (1999) 59 (21): 5560–5564.
Published: 01 November 1999
View article titled, Constitutional <em>von Hippel-Lindau</em> (<em>VHL</em>) Gene Deletions Detected in VHL Families by Fluorescence <em>in Situ</em> Hybridization
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Journal Articles

Third International Meeting on van Hippel-Lindau Disease

Berton Zbar, William Kaelin, Eamonn Maher, Stephane Richard
Journal: Cancer Research
Cancer Res (1999) 59 (9): 2251.
Published: 01 May 1999
View article titled, Third International Meeting on van Hippel-Lindau Disease
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Journal Articles

Somatic Mutations in the Kinase Domain of the Met/Hepatocyte Growth Factor Receptor Gene in Childhood Hepatocellular Carcinomas

Won Sang Park, Seung Myung Dong, Su Young Kim, Eun Young Na, Min Sun Shin, Jae Ho Pi, Bum Jun Kim, Jeong Hoon Bae, Young Ki Hong, Kyo Sun Lee, Sug Hyung Lee, Nam Jin Yoo, Ja June Jang, Svetlana Pack, Zhengping Zhuang, Laura Schmidt, Berton Zbar, Jung Young Lee
Journal: Cancer Research
Cancer Res (1999) 59 (2): 307–310.
Published: 15 January 1999
View article titled, Somatic Mutations in the Kinase Domain of the <em>Met</em>/Hepatocyte Growth Factor Receptor Gene in Childhood Hepatocellular Carcinomas
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Journal Articles

Two North American Families with Hereditary Papillary Renal Carcinoma and Identical Novel Mutations in the MET Proto-Oncogene

Laura Schmidt, Kerstin Junker, Gregor Weirich, Gladys Glenn, Peter Choyke, Irina Lubensky, Zhengping Zhuang, Michael Jeffers, George Vande Woude, Hartmutt Neumann, McClellan Walther, W. Marston Linehan, Berton Zbar
Journal: Cancer Research
Cancer Res (1998) 58 (8): 1719–1722.
Published: 01 April 1998
View article titled, Two North American Families with Hereditary Papillary Renal Carcinoma and Identical Novel Mutations in the MET Proto-Oncogene
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Journal Articles

Loss of Heterozygosity and Somatic Mutations of the VHL Tumor Suppressor Gene in Sporadic Cerebellar Hemangioblastomas

Jung-Young Lee, Seung-Myung Dong, Won-Sang Park, Nam-Jin Yoo, Choo-Soung Kim, Ja-Jun Jang, Je-Geun Chi, Berton Zbar, Irina A. Lubensky, W. Marston Linehan, Alexander O. Vortmeyer, Zhengping Zhuang
Journal: Cancer Research
Cancer Res (1998) 58 (3): 504–508.
Published: 01 February 1998
View article titled, Loss of Heterozygosity and Somatic Mutations of the <em>VHL</em> Tumor Suppressor Gene in Sporadic Cerebellar Hemangioblastomas
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Journal Articles

Construction of a 600-Kilobase Cosmid Clone Contig and Generation of a Transcriptional Map Surrounding the Lung Cancer Tumor Suppressor Gene (TSG) Locus on Human Chromosome 3p21.3: Progress toward the Isolation of a Lung Cancer TSG

Ming-Hui Wei, Farida Latif, Scott Bader, Vladimir Kashuba, Jeou-Yuan Chen, Fuh-Mei Duh, Yoshitaka Sekido, Cheng-Chi Lee, Laura Geil, Igor Kuzmin, Eugene Zabarovsky, George Klein, Berton Zbar, John D. Minna, Michael I. Lerman
Journal: Cancer Research
Cancer Res (1996) 56 (7): 1487–1492.
Published: 01 April 1996
View article titled, Construction of a 600-Kilobase Cosmid Clone Contig and Generation of a Transcriptional Map Surrounding the Lung Cancer Tumor Suppressor Gene (<em>TSG</em>) Locus on Human Chromosome 3p21.3: Progress toward the Isolation of a Lung Cancer TSG
Open the PDF for Construction of a 600-Kilobase Cosmid Clone Contig and Generation of a Transcriptional Map Surrounding the Lung Cancer Tumor Suppressor Gene (<em>TSG</em>) Locus on Human Chromosome 3p21.3: Progress toward the Isolation of a Lung Cancer TSG in another window
Journal Articles

Suppression of Growth of Renal Carcinoma Cells by the von Hippel-Lindau Tumor Suppressor Gene

Fan Chen, Takeshi Kishida, Fuh-Mei Duh, Paul Renbaum, Mary L. Orcutt, Laura Schmidt, Berton Zbar
Journal: Cancer Research
Cancer Res (1995) 55 (21): 4804–4807.
Published: 01 November 1995
View article titled, Suppression of Growth of Renal Carcinoma Cells by the von Hippel-Lindau Tumor Suppressor Gene
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Journal Articles

Cellular Proteins That Bind the von Hippel-Lindau Disease Gene Product: Mapping of Binding Domains and the Effect of Missense Mutations

Takeshi Kishida, Thomas M. Stackhouse, Fan Chen, Michael I. Lerman, Berton Zbar
Journal: Cancer Research
Cancer Res (1995) 55 (20): 4544–4548.
Published: 01 October 1995
View article titled, Cellular Proteins That Bind the von Hippel-Lindau Disease Gene Product: Mapping of Binding Domains and the Effect of Missense Mutations
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Journal Articles

Frequent Somatic Mutations and Loss of Heterozygosity of the von Hippel-Lindau Tumor Suppressor Gene in Primary Human Renal Cell Carcinomas

Taro Shuin, Kelichi Kondo, Soichiro Torigoe, Takeshi Kishida, Yoshinobu Kubota, Masahiko Hosaka, Yoji Nagashima, Hitoshi Kitamura, Farida Latif, Berton Zbar, Michael I. Lerman, Masahiro Yao
Journal: Cancer Research
Cancer Res (1994) 54 (11): 2852–2855.
Published: 01 June 1994
View article titled, Frequent Somatic Mutations and Loss of Heterozygosity of the von Hippel-Lindau Tumor Suppressor Gene in Primary Human Renal Cell Carcinomas
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Journal Articles

One-megabase Yeast Artificial Chromosome and 400-kilobase Cosmid-phage Contigs Containing the von Hippel-Lindau Tumor Suppressor and Ca2+-transporting Adenosine Triphosphatase Isoform 2 Genes

Igor Kuzmin, Thomas Stackhouse, Farida Latif, Fuh-Mei Duh, Laura Geil, James Gnarra, Masahiro Yao, Mary Lou Orcutt, Hua Li, Kalman Tory, Denis Le Paslier, Ilya Chumakov, Daniel Cohen, A. Craig Chinault, W. Marston Linehan, Michael I. Lerman, Berton Zbar
Journal: Cancer Research
Cancer Res (1994) 54 (9): 2486–2491.
Published: 01 May 1994
View article titled, One-megabase Yeast Artificial Chromosome and 400-kilobase Cosmid-phage Contigs Containing the von Hippel-Lindau Tumor Suppressor and Ca<sup>2+</sup>-transporting Adenosine Triphosphatase Isoform 2 Genes
Open the PDF for One-megabase Yeast Artificial Chromosome and 400-kilobase Cosmid-phage Contigs Containing the von Hippel-Lindau Tumor Suppressor and Ca<sup>2+</sup>-transporting Adenosine Triphosphatase Isoform 2 Genes in another window