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Journal Articles

Abstract LB134: Targeting coactivators to inhibit ESR1 fusion-driven breast cancer growth

Xuxu Gou, Craig T. Vollert, Yue Chen, Diana Fandino, Matthew V. Holt, Beom-Jun Kim, Qin Feng, Jin Wang, David M. Lonard, Bert W. O'Malley, Matthew J. Ellis, Charles E. Foulds

Cancer Res (2023) 83 (8_Supplement): LB134.

https://doi.org/10.1158/1538-7445.AM2023-LB134

Published: 14 April 2023

View article titled, Abstract LB134: Targeting coactivators to inhibit ESR1 fusion-driven breast cancer growth

Journal Articles

Abstract A017: Bidirectional signaling between mitochondria and the nucleus dictates epigenetic rewiring to drive tumorigenesis

Abhisha Sawant Dessai, Nadya Elhalawany, Eriko Katsuta, Christian Prechtl, Spencer Rosario, Bert W. O’Malley, Xiang H. Zhang, Subhamoy Dasgupta

Cancer Res (2022) 82 (23_Supplement_2): A017.

https://doi.org/10.1158/1538-7445.CancEpi22-A017

Published: 01 December 2022

View article titled, Abstract A017: Bidirectional signaling between mitochondria and the nucleus dictates epigenetic rewiring to drive tumorigenesis

Journal Articles

Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone

Abhisha Sawant Dessai, Mayrel Palestino Dominguez, Uan-I Chen, John Hasper, Christian Prechtl, Cuijuan Yu, Eriko Katsuta, Tao Dai, Bokai Zhu, Sung Yun Jung, Nagireddy Putluri, Kazuaki Takabe, Xiang H.-F. Zhang, Bert W. O'Malley, Subhamoy Dasgupta

Cancer Res (2021) 81 (1): 50–63.

https://doi.org/10.1158/0008-5472.CAN-20-1708

Published: 04 January 2021

View article titled, Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone

Includes: Supplementary data

Journal Articles

Abstract 1084: TRAF4-mediated NGF receptor TrkA ubiquitination regulates prostate cancer metastasis

Ramesh Singh, Dileep Karri, Jiangyong Shao, Subhamoy Dasgupta, Shixia Huang, Dean P. Edwards, Bert W. O'Malley, Ping Yi

Cancer Res (2018) 78 (13_Supplement): 1084.

https://doi.org/10.1158/1538-7445.AM2018-1084

Published: 01 July 2018

View article titled, Abstract 1084: TRAF4-mediated NGF receptor TrkA ubiquitination regulates prostate cancer metastasis

Journal Articles

Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells

Aarti D. Rohira, Fei Yan, Lei Wang, Jin Wang, Suoling Zhou, Andrew Lu, Yang Yu, Jianming Xu, David M. Lonard, Bert W. O'Malley

Cancer Res (2017) 77 (16): 4293–4304.

https://doi.org/10.1158/0008-5472.CAN-16-2982

Published: 14 August 2017

View article titled, Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells

Includes: Supplementary data

Journal Articles

Abstract 2579: Identifying pathways that regulate the turnover of gain-of-function p53 mutant proteins in ovarian cancer cells

Achuth Padmanabhan, Nicholes Candelaria, Kwong-Kwok Wong, Bryan C. Nikolai, David Lonard, Bert W. O'Malley, JoAnne S. Richards

Cancer Res (2017) 77 (13_Supplement): 2579.

https://doi.org/10.1158/1538-7445.AM2017-2579

Published: 01 July 2017

View article titled, Abstract 2579: Identifying pathways that regulate the turnover of gain-of-function p53 mutant proteins in ovarian cancer cells

Journal Articles

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Bryan C. Nikolai, Rainer B. Lanz, Brian York, Subhamoy Dasgupta, Nicholas Mitsiades, Chad J. Creighton, Anna Tsimelzon, Susan G. Hilsenbeck, David M. Lonard, Carolyn L. Smith, Bert W. O'Malley

Cancer Res (2016) 76 (6): 1463–1475.

https://doi.org/10.1158/0008-5472.CAN-15-2383

Published: 14 March 2016

View article titled, HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Includes: Supplementary data

Journal Articles

Abstract 5474: PD-L1 regulates cisplatin chemoresistance in head and neck squamous cell carcinoma

Randall S. Ruffner, Andrew Ramsey, Bert W. O'Malley, Daqing Li

Cancer Res (2015) 75 (15_Supplement): 5474.

https://doi.org/10.1158/1538-7445.AM2015-5474

Published: 01 August 2015

View article titled, Abstract 5474: PD-L1 regulates cisplatin chemoresistance in head and neck squamous cell carcinoma

Journal Articles

Bufalin Is a Steroid Receptor Coactivator Inhibitor—Response

David M. Lonard, Jianming Xu, Bert W. O'Malley

Cancer Res (2015) 75 (6): 1157.

https://doi.org/10.1158/0008-5472.CAN-14-2648

Published: 12 March 2015

View article titled, Bufalin Is a Steroid Receptor Coactivator Inhibitor—Response

Journal Articles

Abstract 3750: Targeting PD-L1 sensitizes head and neck squamous cell carcinoma to cisplatin

Peter Qiao, Shayanne A. Lajud, Danish A. Nagda, Nobuaki Tanaka, Alyssa Civantos, Bert W. O'Malley, Daqing Li

Cancer Res (2014) 74 (19_Supplement): 3750.

https://doi.org/10.1158/1538-7445.AM2014-3750

Published: 01 October 2014

View article titled, Abstract 3750: Targeting PD-L1 sensitizes head and neck squamous cell carcinoma to cisplatin

Journal Articles

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Ying Wang, David M. Lonard, Yang Yu, Dar-Chone Chow, Timothy G. Palzkill, Jin Wang, Ruogu Qi, Alexander J. Matzuk, Xianzhou Song, Franck Madoux, Peter Hodder, Peter Chase, Patrick R. Griffin, Suoling Zhou, Lan Liao, Jianming Xu, Bert W. O'Malley

Cancer Res (2014) 74 (5): 1506–1517.

https://doi.org/10.1158/0008-5472.CAN-13-2939

Published: 02 March 2014

View article titled, Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Journal Articles

Abstract 2263: Biliverdin inhibits head and neck cancer cell growth via activation of retinoblastoma signaling pathway.

Jun Zheng, Danish A. Nagda, Shayanne A. Lajud, Sanjeev Kumar, Anas Mouchli, Orysia Bezpalko, Bert W. O'Malley, Daqing Li

Cancer Res (2013) 73 (8_Supplement): 2263.

https://doi.org/10.1158/1538-7445.AM2013-2263

Published: 15 April 2013

View article titled, Abstract 2263: Biliverdin inhibits head and neck cancer cell growth via activation of retinoblastoma signaling pathway.

Journal Articles

Abstract 3748: The Mre11/Rad50/Nbs1 (MRN) complex: A critical mediator of chemoresistance and cancer stem cell progression in head and neck squamous cell carcinoma.

Danish Nagda, Shayanne A. Lajud, Taku Yamashita, Sanjeev Kumar, Jun Zheng, Peter Qiao, Orysia Bezpalko, Bert W. O'Malley, Daqing Li

Cancer Res (2013) 73 (8_Supplement): 3748.

https://doi.org/10.1158/1538-7445.AM2013-3748

Published: 15 April 2013

View article titled, Abstract 3748: The Mre11/Rad50/Nbs1 (MRN) complex: A critical mediator of chemoresistance and cancer stem cell progression in head and neck squamous cell carcinoma.

Journal Articles

Abstract 3072: HER2 signaling affects SRC-3 phosphorylation and gene regulatory potential within the cistrome

Bryan C. Nikolai, Carolyn L. Smith, Bert W. O'Malley

Cancer Res (2012) 72 (8_Supplement): 3072.

https://doi.org/10.1158/1538-7445.AM2012-3072

Published: 15 April 2012

View article titled, Abstract 3072: HER2 signaling affects SRC-3 phosphorylation and gene regulatory potential within the cistrome

Journal Articles

Abstract 3111: Synthetic lethality in head and neck cancer

Shayanne A. Lajud, Taku Yamashita, Ziying Han, Jun Zheng, Anas Mouchli, Orysia Bezpalko, Bert W. O'Malley, Daqing Li

Cancer Res (2012) 72 (8_Supplement): 3111.

https://doi.org/10.1158/1538-7445.AM2012-3111

Published: 15 April 2012

View article titled, Abstract 3111: Synthetic lethality in head and neck cancer

Journal Articles

Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism

Subhamoy Dasgupta, Bin Zhang, Jean-Francois Louet, Bert W. O'Malley

Cancer Res (2012) 72 (8_Supplement): 5153.

https://doi.org/10.1158/1538-7445.AM2012-5153

Published: 15 April 2012

View article titled, Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism

Journal Articles

Abstract 4051: A mouse model of head and neck cancer with infrared-based molecular imaging

Anas Mouchli, Ziying Han, Jun Zheng, Shayanne A. Lajud, Bert W. O'Malley, Daqing Li

Cancer Res (2012) 72 (8_Supplement): 4051.

https://doi.org/10.1158/1538-7445.AM2012-4051

Published: 15 April 2012

View article titled, Abstract 4051: A mouse model of head and neck cancer with infrared-based molecular imaging

Journal Articles

Abstract 1411: A novel molecular approach for head and neck cancer radiosensitization

Shunsuke Miyamoto, Hui Wang, Taku Yamashita, Daqing Li, Bert W. O'Malley

Cancer Res (2010) 70 (8_Supplement): 1411.

https://doi.org/10.1158/1538-7445.AM10-1411

Published: 15 April 2010

View article titled, Abstract 1411: A novel molecular approach for head and neck cancer radiosensitization

Journal Articles

Abstract 3093: Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness

Yixiang Xu, Qiang Chen, Wengang Li, Xinhui Su, Tenghui Chen, Yonghong Liu, Yang Zhao, Bert W. O'Malley, Chundong Yu

Cancer Res (2010) 70 (8_Supplement): 3093.

https://doi.org/10.1158/1538-7445.AM10-3093

Published: 15 April 2010

View article titled, Abstract 3093: Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness

Journal Articles

Abstract 2573: Molecular mechanism of cisplatin-based chemoresistance with human head and neck cancer: A translational clinical study

Taku Yamashita, Shunsuke Miyamoto, Wei-Ting Hwang, Bert W. O'Malley, Daqing Li

Cancer Res (2010) 70 (8_Supplement): 2573.

https://doi.org/10.1158/1538-7445.AM10-2573

Published: 15 April 2010

View article titled, Abstract 2573: Molecular mechanism of cisplatin-based chemoresistance with human head and neck cancer: A translational clinical study

NARROW

Abstract LB134: Targeting coactivators to inhibit ESR1 fusion-driven breast cancer growth

Abstract A017: Bidirectional signaling between mitochondria and the nucleus dictates epigenetic rewiring to drive tumorigenesis

Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone

Abstract 1084: TRAF4-mediated NGF receptor TrkA ubiquitination regulates prostate cancer metastasis

Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells

Abstract 2579: Identifying pathways that regulate the turnover of gain-of-function p53 mutant proteins in ovarian cancer cells

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Abstract 5474: PD-L1 regulates cisplatin chemoresistance in head and neck squamous cell carcinoma

Bufalin Is a Steroid Receptor Coactivator Inhibitor—Response

Abstract 3750: Targeting PD-L1 sensitizes head and neck squamous cell carcinoma to cisplatin

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Abstract 2263: Biliverdin inhibits head and neck cancer cell growth via activation of retinoblastoma signaling pathway.

Abstract 3748: The Mre11/Rad50/Nbs1 (MRN) complex: A critical mediator of chemoresistance and cancer stem cell progression in head and neck squamous cell carcinoma.

Abstract 3072: HER2 signaling affects SRC-3 phosphorylation and gene regulatory potential within the cistrome

Abstract 3111: Synthetic lethality in head and neck cancer

Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism

Abstract 4051: A mouse model of head and neck cancer with infrared-based molecular imaging

Abstract 1411: A novel molecular approach for head and neck cancer radiosensitization

Abstract 3093: Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness

Abstract 2573: Molecular mechanism of cisplatin-based chemoresistance with human head and neck cancer: A translational clinical study

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