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Benjamin Purow
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Journal Articles

Abstract 4205: Staged anti-PD-1 therapy with intratumoral recombinant calreticulin improves anti-tumor immunity and survival in glioblastoma mouse models

Suchet Taori, Breanna Noffsinger, Charlotte A. Miller, Aizhen Xiao, Laryssa Manigat, Qing Zhong, Tajie Harris, Benjamin Purow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4205.
https://doi.org/10.1158/1538-7445.AM2022-4205
Published: 15 June 2022
View article titled, Abstract 4205: Staged anti-PD-1 therapy with intratumoral recombinant calreticulin improves anti-tumor immunity and survival in glioblastoma mouse models
Journal Articles

Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition

Evan K. Day, Qing Zhong, Benjamin Purow, Matthew J. Lazzara
Journal: Cancer Research
Cancer Res (2021) 81 (8): 2056–2070.
https://doi.org/10.1158/0008-5472.CAN-20-1756
Published: 15 April 2021
View article titled, Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 4284: Targeting notch signaling in glioblastoma cancer stem cells through modulation of Connexin43 function

Michael Lunski, James Smyth, Jennifer Vaughn, Zhi Sheng, Robert Gourdie, Benjamin Purow, Samy Lamouille
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4284.
https://doi.org/10.1158/1538-7445.AM2019-4284
Published: 01 July 2019
View article titled, Abstract 4284: Targeting notch signaling in glioblastoma cancer stem cells through modulation of Connexin43 function
Journal Articles

Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma

Inan Olmez, Ying Zhang, Laryssa Manigat, Mouadh Benamar, Breanna Brenneman, Ichiro Nakano, Jakub Godlewski, Agnieszka Bronisz, Jeongwu Lee, Tarek Abbas, Roger Abounader, Benjamin Purow
Journal: Cancer Research
Cancer Res (2018) 78 (15): 4360–4369.
https://doi.org/10.1158/0008-5472.CAN-17-3124
Published: 31 July 2018
View article titled, Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma
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Includes: Supplementary data
Journal Articles

Abstract 542: Assessing and augmenting the immune response to glioblastoma using repurposed pharmaceuticals

Breanna R. Brenneman, Desiree H. Floyd, Tajie Harris, Benjamin Purow
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 542.
https://doi.org/10.1158/1538-7445.AM2016-542
Published: 15 July 2016
View article titled, Abstract 542: Assessing and augmenting the immune response to glioblastoma using repurposed pharmaceuticals
Journal Articles

Abstract 1909: Identification and characterization of microRNA-134 as a novel receptor tyrosine kinase-regulated tumor suppressive hub in glioblastoma

Ying Zhang, Jungeun Kim, Adam C. Mueller, Bijan Dey, Yanzhi Yang, Daehee Lee, Jan Hachmann, Sanjo Finderle, Deric M. Park, James Christensen, David Schiff, Benjamin Purow, Anindya Dutta, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1909.
https://doi.org/10.1158/1538-7445.AM2014-1909
Published: 01 October 2014
View article titled, Abstract 1909: Identification and characterization of microRNA-134 as a novel receptor tyrosine kinase-regulated tumor suppressive hub in glioblastoma
Journal Articles

Abstract 5222: microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma

Jungeun Kim, Ying Zhang, Michael Skalski, Josie Hayes, Benjamin Kefas, David Schiff, Benjamin Purow, Sarah Parsons, Sean Lawler, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5222.
https://doi.org/10.1158/1538-7445.AM2014-5222
Published: 01 October 2014
View article titled, Abstract 5222: microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma
Journal Articles

microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma

Jungeun Kim, Ying Zhang, Michael Skalski, Josie Hayes, Benjamin Kefas, David Schiff, Benjamin Purow, Sarah Parsons, Sean Lawler, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1541–1553.
https://doi.org/10.1158/0008-5472.CAN-13-1449
Published: 02 March 2014
View article titled, microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma
Open the PDF for microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1821: Hepatocyte growth factor sensitizes brain tumor cells and xenografts to c-Met kinase inhibition

Ying Zhang, Kaithlyn Farenholtz, Yanzhi Yang, Fadila Guessous, David Schiff, Benjamin Purow, James Christensen, Roger Abounader
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1821.
https://doi.org/10.1158/1538-7445.AM2012-1821
Published: 15 April 2012
View article titled, Abstract 1821: Hepatocyte growth factor sensitizes brain tumor cells and xenografts to c-Met kinase inhibition
Journal Articles

Abstract 4691: Inhibition of ubiquitin specific protease Usp18 reduces cancer cell proliferation by down regulating multiple proto-oncogenes including EGFR

Jason E. Duex, Benjamin Kefas, Benjamin Purow, Alexander Sorkin
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4691.
https://doi.org/10.1158/1538-7445.AM2011-4691
Published: 15 April 2011
View article titled, Abstract 4691: Inhibition of ubiquitin specific protease Usp18 reduces cancer cell proliferation by down regulating multiple proto-oncogenes including EGFR
Journal Articles

Abstract 2067: Effects of microRNA-34a on brain tumor cells and glioblastoma stem cells

Fadila Guessous, Ying Zhang, Alessia Catania, Yunqing Li, Alexander Kofman, Benjamin Kefas, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2067.
https://doi.org/10.1158/1538-7445.AM10-2067
Published: 15 April 2010
View article titled, Abstract 2067: Effects of microRNA-34a on brain tumor cells and glioblastoma stem cells
Journal Articles

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

Yunqing Li, Fadila Guessous, Ying Zhang, Charles DiPierro, Benjamin Kefas, Elizabeth Johnson, Lukasz Marcinkiewicz, Jinmai Jiang, Yanzhi Yang, Thomas D. Schmittgen, Beatriz Lopes, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7569–7576.
https://doi.org/10.1158/0008-5472.CAN-09-0529
Published: 01 October 2009
View article titled, MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
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Journal Articles

Abstract #2642: A Notch/microRNA-326 feedback loop regulating glioma cell survival

Benjamin Kefas, Laurey Comeau, Tom Schmittgen, Jakub Godlewski, Sean Lawler, Benjamin Purow
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2642.
Published: 01 May 2009
View article titled, Abstract #2642: A Notch/microRNA-326 feedback loop regulating glioma cell survival
Journal Articles

Abstract #1966: microRNA-34a inhibits brain tumor growth by targeting multiple oncogenes

Yunqing Li, Fadila Guessous, Charles Dipierro, Ying Zhang, Benjamin Kefas, Elizabeth Johnson, Jinmai Jiang, Beatriz Lopes, David Schiff, Thomas Schmittgen, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1966.
Published: 01 May 2009
View article titled, Abstract #1966: microRNA-34a inhibits brain tumor growth by targeting multiple oncogenes
Journal Articles

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

Benjamin Kefas, Jakub Godlewski, Laurey Comeau, Yunqing Li, Roger Abounader, Michael Hawkinson, Jeongwu Lee, Howard Fine, E. Antonio Chiocca, Sean Lawler, Benjamin Purow
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3566–3572.
https://doi.org/10.1158/0008-5472.CAN-07-6639
Published: 15 May 2008
View article titled, microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma
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Journal Articles

microRNA-34a is a tumor suppressor that inhibits c-Met in human gliomas.

Yunqing Li, Fadila Guessous, Elizabeth Johnson, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5022.
Published: 01 May 2008
View article titled, microRNA-34a is a tumor suppressor that inhibits c-Met in human gliomas.
Journal Articles

microRNA-7 is a putative tumor suppressor in glioblastoma inhibiting both EGFR and the Akt pathway

Benjamin Kefas, Jakub Godlewski, Laurey Comeau, Yunqing Li, Roger Abounader, Jeongwu Lee, Howard Fine, E. Antonio Chiocca, Sean Lawler, Benjamin Purow
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5021.
Published: 01 May 2008
View article titled, microRNA-7 is a putative tumor suppressor in glioblastoma inhibiting both EGFR and the Akt pathway
Journal Articles

The Notch ligand Delta-like-1 regulates Rheb expression and mTOR activity through a Notch-independent mechanism

Tilak Sundaresan, Howard Fine, Benjamin Purow
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-191.
Published: 01 May 2007
View article titled, The Notch ligand Delta-like-1 regulates Rheb expression and mTOR activity through a Notch-independent mechanism
Journal Articles

Notch-1 regulates expression of the epidermal growth factor receptor

Tilak K. Sundaresan, Benjamin Purow, Howard A. Fine
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 931.
Published: 15 April 2006
View article titled, Notch-1 regulates expression of the epidermal growth factor receptor
Journal Articles

Orthotopic Growth of Human Glioma Cells Quantitatively and Qualitatively Influences Radiation-Induced Changes in Gene Expression

Kevin Camphausen, Benjamin Purow, Mary Sproull, Tamalee Scott, Tomoko Ozawa, Dennis F. Deen, Philip J. Tofilon
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10389–10393.
https://doi.org/10.1158/0008-5472.CAN-05-1904
Published: 15 November 2005
View article titled, Orthotopic Growth of Human Glioma Cells Quantitatively and Qualitatively Influences Radiation-Induced Changes in Gene Expression
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