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Journal Articles

Abstract 3795: Cross-HLA targeting of synthetic neoepitopes with T cell engagers to eradicate sotorasib-resistant, KRAS-G12C mutant cancer

Cancer Res (2025) 85 (8_Supplement_1): 3795.

https://doi.org/10.1158/1538-7445.AM2025-3795

Published: 21 April 2025

View articletitled, Abstract 3795: Cross-HLA targeting of synthetic neoepitopes with T cell engagers to eradicate sotorasib-resistant, KRAS-G12C mutant cancer

Journal Articles

Abstract LB052: PTP1B inhibitors activate a novel hypoxia-induced inflammatory cell death pathway in breast cancer

Benjamin G. Neel, Abhishek Bhardwaj, Maria Antonelli, Beatrix Ueberheide

Cancer Res (2024) 84 (7_Supplement): LB052.

https://doi.org/10.1158/1538-7445.AM2024-LB052

Published: 05 April 2024

View articletitled, Abstract LB052: PTP1B inhibitors activate a novel hypoxia-induced inflammatory cell death pathway in breast cancer

Journal Articles

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRAS^G12C Inhibitor Efficacy

Cancer Res (2023) 83 (24): 4095–4111.

https://doi.org/10.1158/0008-5472.CAN-23-2729

Published: 15 December 2023

View articletitled, Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

Includes: Supplementary data

Journal Articles

Abstract 659: Mechanisms of resistance to SHP2 inhibition

Wei Wei, Mitchell Geer, Xinyi Guo, Neville Sanjana, Benjamin G. Neel

Cancer Res (2022) 82 (12_Supplement): 659.

https://doi.org/10.1158/1538-7445.AM2022-659

Published: 15 June 2022

View articletitled, Abstract 659: Mechanisms of resistance to SHP2 inhibition

Journal Articles

Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma

Yang Xu, Paul Taylor, Joshua Andrade, Beatrix Ueberheide, Brian Shuch, Peter M. Glazer, Ranjit S. Bindra, Michael F. Moran, W. Marston Linehan, Benjamin G. Neel

Cancer Res (2018) 78 (23): 6539–6548.

https://doi.org/10.1158/0008-5472.CAN-18-0901

Published: 03 December 2018

View articletitled, Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma

Includes: Supplementary data

Journal Articles

Abstract LB-338: SHP2 inhibition enhances sensitivity to MEK inhibitors in multiple resistant cancer models

Carmine Fedele, Kwan Ho Tang, Hao Ran, Wei Wei, Brian Diskin, George Miller, Benjamin G. Neel

Cancer Res (2018) 78 (13_Supplement): LB-338.

https://doi.org/10.1158/1538-7445.AM2018-LB-338

Published: 01 July 2018

View articletitled, Abstract LB-338: SHP2 inhibition enhances sensitivity to MEK inhibitors in multiple resistant cancer models

Journal Articles

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Samantha Le Sommer, Nicola Morrice, Martina Pesaresi, Dawn Thompson, Mark A. Vickers, Graeme I. Murray, Nimesh Mody, Benjamin G. Neel, Kendra K. Bence, Heather M. Wilson, Mirela Delibegović

Cancer Res (2018) 78 (1): 75–87.

https://doi.org/10.1158/0008-5472.CAN-17-0946

Published: 02 January 2018

View articletitled, Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Includes: Supplementary data

Journal Articles

Abstract A2-07: Integrative functional genomics of breast cancer

Richard Marcotte, Azin Sayad, Cathy Iorio, Jason Moffat, Benjamin G. Neel

Cancer Res (2015) 75 (22_Supplement_1): A2-07.

https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-07

Published: 15 November 2015

View articletitled, Abstract A2-07: Integrative functional genomics of breast cancer

Journal Articles

Abstract PR14: Integrative functional genomics of breast cancer

Richard Marcotte, Azin Sayad, Cathy Iorio, Jason Moffat, Benjamin G. Neel

Cancer Res (2015) 75 (22_Supplement_2): PR14.

https://doi.org/10.1158/1538-7445.COMPSYSBIO-PR14

Published: 15 November 2015

View articletitled, Abstract PR14: Integrative functional genomics of breast cancer

Journal Articles

Abstract B2-06: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Shengqing Gu, Stephanie Lheureux, Azin Sayad, Liat Frida Hogen, Iryna Vyarvelska, Paulina Cybulska, Marcus Bernardini, Barry Rosen, Amit Oza, Benjamin G. Neel

Cancer Res (2015) 75 (22_Supplement_2): B2-06.

https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-06

Published: 15 November 2015

View articletitled, Abstract B2-06: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Journal Articles

Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia

Robert S. Banh, Caterina Iorio, Richard Marcotte, Yang Xu, Dan Cojocari, Anas Abdel Rahman, Judy Pawling, Ankit Sinha, Toshiaki Hitomi, Toshiyuki Habu, Akio Koizumi, Sarah Wilkins, Thomas Kislinger, Christopher J. Schofield, James W. Dennis, Bradly G. Wouters, Benjamin G. Neel

Cancer Res (2015) 75 (15_Supplement): LB-302.

https://doi.org/10.1158/1538-7445.AM2015-LB-302

Published: 01 August 2015

View articletitled, Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia

Journal Articles

Abstract LB-307: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Shengqing Gu, Liat Hogen, Stephanie Lheureux, Azin Sayad, Iryna Vyarvelska, Paulina Cybulska, Marcus Bernardini, Barry Rosen, Amit Oza, Benjamin G. Neel

Cancer Res (2015) 75 (15_Supplement): LB-307.

https://doi.org/10.1158/1538-7445.AM2015-LB-307

Published: 01 August 2015

View articletitled, Abstract LB-307: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Journal Articles

Abstract B43: Role of activated SHP2 in high-risk neuroblastoma pathogenesis

(Jane) shizhen Zhu, Benjamin G. Neel, A. Thomas Look

Cancer Res (2014) 74 (20_Supplement): B43.

https://doi.org/10.1158/1538-7445.PEDCAN-B43

Published: 09 October 2014

View articletitled, Abstract B43: Role of activated SHP2 in high-risk neuroblastoma pathogenesis

Journal Articles

Abstract 80: Activated SHP2 collaborates with MYCN in neuroblastoma tumorigenesis

Xiaoling Zhang, Guang Yang, A.Thomas Look, Benjamin G. Neel, Shizhen (Jane) Zhu

Cancer Res (2014) 74 (19_Supplement): 80.

https://doi.org/10.1158/1538-7445.AM2014-80

Published: 01 October 2014

View articletitled, Abstract 80: Activated SHP2 collaborates with MYCN in neuroblastoma tumorigenesis

Journal Articles

Abstract LB-230: A prospective clinical trial to evaluate DNA sequencing as a diagnostic tool to guide cancer therapy: results from the initial 50 patients

Cancer Res (2012) 72 (8_Supplement): LB-230.

https://doi.org/10.1158/1538-7445.AM2012-LB-230

Published: 15 April 2012

View articletitled, Abstract LB-230: A prospective clinical trial to evaluate DNA sequencing as a diagnostic tool to guide cancer therapy: results from the initial 50 patients

Journal Articles

Abstract 5084: Functional genomic classification of breast cancer using pooled lentivirus shRNA screens

Richard Marcotte, Kevin Brown, Azin Sayad, Maliha Haider, Troy Ketela, Jason Moffat, Benjamin G. Neel

Cancer Res (2012) 72 (8_Supplement): 5084.

https://doi.org/10.1158/1538-7445.AM2012-5084

Published: 15 April 2012

View articletitled, Abstract 5084: Functional genomic classification of breast cancer using pooled lentivirus shRNA screens

Journal Articles

Abstract 3318: Phenotypic heterogeneity and instability of tumor-initiating cells in high-grade serous cancer

Jocelyn M. Stewart, Patricia A. Shaw, Marcus Q. Bernardini, Laurie E. Ailles, Benjamin G. Neel

Cancer Res (2012) 72 (8_Supplement): 3318.

https://doi.org/10.1158/1538-7445.AM2012-3318

Published: 15 April 2012

View articletitled, Abstract 3318: Phenotypic heterogeneity and instability of tumor-initiating cells in high-grade serous cancer

Journal Articles

Abstract 1352: Shp2 is required for CML initiation and maintenance

Shengqing Gu, Gordon Chan, Benjamin G. Neel

Cancer Res (2012) 72 (8_Supplement): 1352.

https://doi.org/10.1158/1538-7445.AM2012-1352

Published: 15 April 2012

View articletitled, Abstract 1352: Shp2 is required for CML initiation and maintenance

Journal Articles

Abstract 1232: Overcoming resistance to EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer

J Rafael Sierra, Anderson Chang, Jason Moffat, Benjamin G. Neel, Ming-Sound Tsao

Cancer Res (2012) 72 (8_Supplement): 1232.

https://doi.org/10.1158/1538-7445.AM2012-1232

Published: 15 April 2012

View articletitled, Abstract 1232: Overcoming resistance to EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer

Journal Articles

Abstract SY35-02: Phenotypic heterogeneity and instability of human serous ovarian cancer tumor-initiating cells

Benjamin G. Neel, Jocelyn M. Stewart, Bernd Bodenmiller, Laurie Ailles, Craig Gedye, Marcus Bernardini, Patricia A. Shaw, Wendy Fantl, Garry P. Nolan

Cancer Res (2012) 72 (8_Supplement): SY35-02.

https://doi.org/10.1158/1538-7445.AM2012-SY35-02

Published: 15 April 2012

View articletitled, Abstract SY35-02: Phenotypic heterogeneity and instability of human serous ovarian cancer tumor-initiating cells

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Abstract 3795: Cross-HLA targeting of synthetic neoepitopes with T cell engagers to eradicate sotorasib-resistant, KRAS-G12C mutant cancer

Abstract LB052: PTP1B inhibitors activate a novel hypoxia-induced inflammatory cell death pathway in breast cancer

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRAS^G12C Inhibitor Efficacy

Abstract 659: Mechanisms of resistance to SHP2 inhibition

Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma

Abstract LB-338: SHP2 inhibition enhances sensitivity to MEK inhibitors in multiple resistant cancer models

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Abstract A2-07: Integrative functional genomics of breast cancer

Abstract PR14: Integrative functional genomics of breast cancer

Abstract B2-06: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia

Abstract LB-307: Computational modeling of serous ovarian carcinoma dynamics: Implications for screening and therapy

Abstract B43: Role of activated SHP2 in high-risk neuroblastoma pathogenesis

Abstract 80: Activated SHP2 collaborates with MYCN in neuroblastoma tumorigenesis

Abstract LB-230: A prospective clinical trial to evaluate DNA sequencing as a diagnostic tool to guide cancer therapy: results from the initial 50 patients

Abstract 5084: Functional genomic classification of breast cancer using pooled lentivirus shRNA screens

Abstract 3318: Phenotypic heterogeneity and instability of tumor-initiating cells in high-grade serous cancer

Abstract 1352: Shp2 is required for CML initiation and maintenance

Abstract 1232: Overcoming resistance to EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer

Abstract SY35-02: Phenotypic heterogeneity and instability of human serous ovarian cancer tumor-initiating cells

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