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Journal Articles

Abstract P4-08-19: Biomarker analysis: Multi-omics elucidation of Cohort 1 from a phase II study of a triple combination of Atezolizumab + cobimetinib + eribulin in patients with metastatic inflammatory breast cancer

Bora Lim, Angela Alexander, Jie S. Willey, Huiming Sun, Suyu Liu, Anisha B. Patel, Edwin Roger Parra, Cara Haymaker, Luisa Solis Soto, Alejandra Serrano, Baohua Sun, Cibelle Freitas Pinto Lima, Auriole Tamegnon, Renganayaki K. Pandurengan, Dzifa Douse, Jessica Lan, Luthra Raja, Randy Chu, Mark Knafl, Scott E. Woodman, Haifeng Zhu, Katja Shulze, Katherine Fedenko, Walter Darbonne, Naoto T. Ueno, Vicente Valero
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-08-19.
https://doi.org/10.1158/1538-7445.SABCS22-P4-08-19
Published: 01 March 2023
View article titled, Abstract P4-08-19: Biomarker analysis: Multi-omics elucidation of Cohort 1 from a phase II study of a triple combination of Atezolizumab + cobimetinib + eribulin in patients with metastatic inflammatory breast cancer
Journal Articles

Abstract 3884: Novel RUNX1 targeted therapy for AML expressing mutant RUNX1

Christopher P. Mill, Courtney D. DiNardo, Warren Fiskus, Dyana T. Saenz, Agnieszka J. Nowak, Baohua Sun, David N. Saenz, Steven M. Kornblau, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3884.
https://doi.org/10.1158/1538-7445.AM2018-3884
Published: 01 July 2018
View article titled, Abstract 3884: Novel RUNX1 targeted therapy for AML expressing mutant RUNX1
Journal Articles

Abstract 802: Targeted inhibition of KDM1A and BET proteins or DNMT1 exerts synergistic lethal activity against human AML blast progenitor cells

Warren C. Fiskus, Christopher P. Mill, Dyana T. Saenz, Agnieszka J. Nowak, Baohua Sun, David N. Saenz, Steven M. Kornblau, Sunil Sharma, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 802.
https://doi.org/10.1158/1538-7445.AM2018-802
Published: 01 July 2018
View article titled, Abstract 802: Targeted inhibition of KDM1A and BET proteins or DNMT1 exerts synergistic lethal activity against human AML blast progenitor cells
Journal Articles

Abstract LB-081: Novel and effective RUNX1-targeted therapy for AML expressing RUNX1 mutation

Christopher P. Mill, Courtney DiNardo, Warren C. Fiskus, Dyana T. Saenz, Baohua Sun, Agnieszka J. Nowak, Misun Kim, Mark Routbort, Koichi Takahashi, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-081.
https://doi.org/10.1158/1538-7445.AM2017-LB-081
Published: 01 July 2017
View article titled, Abstract LB-081: Novel and effective RUNX1-targeted therapy for AML expressing RUNX1 mutation
Journal Articles

Abstract 5067: BET protein proteolysis targeting chimera (BETP-PROTACs) exert more potent activity than BETP bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm (MPN) secondary (s) AML cells

Dyana T. Saenz, Warren C. Fiskus, Kanak Raina, Taghi Manshouri, Kevin G. Coleman, Yimin Qian, Andrew P. Crew, Angela Shen, Christopher P. Mill, Baohua Sun, Misun Kim, Agnieszka J. Nowak, Srdan Verstovsek, Craig M. Crews, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5067.
https://doi.org/10.1158/1538-7445.AM2017-5067
Published: 01 July 2017
View article titled, Abstract 5067: BET protein proteolysis targeting chimera (BETP-PROTACs) exert more potent activity than BETP bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm (MPN) secondary (s) AML cells
Journal Articles

SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents

Warren Fiskus, Veena Coothankandaswamy, Jianguang Chen, Hongwei Ma, Kyungsoo Ha, Dyana T. Saenz, Stephanie S. Krieger, Christopher P. Mill, Baohua Sun, Peng Huang, Jeffrey S. Mumm, Ari M. Melnick, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5467–5478.
https://doi.org/10.1158/0008-5472.CAN-16-0126
Published: 15 September 2016
View article titled, SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents
Open the PDF for SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents in another window
Includes: Supplementary data
Journal Articles

Abstract 4699: Superior lethal activity of single agent BET protein PROTAC compared to bromodomain inhibitor or in combination with JAK inhibitor against post-myelofibrosis secondary AML cells

Dyana T. Saenz, Warren C. Fiskus, Taghi Manshouri, Jing Lu, Yimin Qian, Kanak Raina, Baohua Sun, Stephanie S. Krieger, Simrit Parmar, Srdan Verstovsek, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4699.
https://doi.org/10.1158/1538-7445.AM2016-4699
Published: 15 July 2016
View article titled, Abstract 4699: Superior lethal activity of single agent BET protein PROTAC compared to bromodomain inhibitor or in combination with JAK inhibitor against post-myelofibrosis secondary AML cells
Journal Articles

Abstract 2623: Molecular mechanism of synergy between BET-protein bromodomain antagonist (BA) and pTEFb kinase inhibitor against human AML blast progenitor cells

Santhana G. T. Devaraj, Bhavin Shah, Warren Fiskus, Baohua Sun, Saikat Saha, Sai Ravi Pingali, Swaminathan P. Iyer, Sunil Sharma, James E. Bradner, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2623.
https://doi.org/10.1158/1538-7445.AM2015-2623
Published: 01 August 2015
View article titled, Abstract 2623: Molecular mechanism of synergy between BET-protein bromodomain antagonist (BA) and pTEFb kinase inhibitor against human AML blast progenitor cells
Journal Articles

Abstract 2612: BET-protein bromodomain antagonist-based combinations against ibrutinb-sensitive or resistant human Mantle Cell Lymphoma cells

Baohua Sun, Bhavin Shah, Warren Fiskus, Jun Qi, Santhana G. T. Devaraj, Swaminathan P. Iyer, Sunil Sharma, James E. Bradner, Youli Zu, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2612.
https://doi.org/10.1158/1538-7445.AM2015-2612
Published: 01 August 2015
View article titled, Abstract 2612: BET-protein bromodomain antagonist-based combinations against ibrutinb-sensitive or resistant human Mantle Cell Lymphoma cells
Journal Articles

Absence of pRb facilitates E2F1-induced cell death in breast cancer cells

Baohua Sun, Stephen G. Swisher, Khandan Keyomarsi, Kelly K. Hunt
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 822.
Published: 01 May 2005
View article titled, Absence of pRb facilitates E2F1-induced cell death in breast cancer cells