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B. Douglas Smith
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Journal Articles

CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia

Husheng Ding, Nicole D. Vincelette, Cordelia D. McGehee, Mira A. Kohorst, Brian D. Koh, Annapoorna Venkatachalam, X. Wei Meng, Paula A. Schneider, Karen S. Flatten, Kevin L. Peterson, Cristina Correia, Sun-Hee Lee, Mrinal Patnaik, Jonathan A. Webster, Gabriel Ghiaur, B. Douglas Smith, Judith E. Karp, Keith W. Pratz, Hu Li, Larry M. Karnitz, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2666–2678.
https://doi.org/10.1158/0008-5472.CAN-20-1504
Published: 15 May 2021
View article titled, CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia
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Includes: Supplementary data
Journal Articles

Progressive Chromatin Repression and Promoter Methylation of CTNNA1 Associated with Advanced Myeloid Malignancies

Ying Ye, Michael A. McDevitt, Mingzhou Guo, Wei Zhang, Oliver Galm, Steven D. Gore, Judith E. Karp, Jaroslaw P. Maciejewski, Jeanne Kowalski, Hua-Ling Tsai, Lukasz P. Gondek, Hsing-Chen Tsai, Xiaofei Wang, Craig Hooker, B. Douglas Smith, Hetty E. Carraway, James G. Herman
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8482–8490.
https://doi.org/10.1158/0008-5472.CAN-09-1153
Published: 28 October 2009
View article titled, Progressive Chromatin Repression and Promoter Methylation of <em>CTNNA1</em> Associated with Advanced Myeloid Malignancies
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Includes: Supplementary data
Journal Articles

Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 In vitro

Andrea E. Wahner Hendrickson, Paul Haluska, Paula A. Schneider, David A. Loegering, Kevin L. Peterson, Ricardo Attar, B. Douglas Smith, Charles Erlichman, Marco Gottardis, Judith E. Karp, Joan M. Carboni, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7635–7643.
https://doi.org/10.1158/0008-5472.CAN-09-0511
Published: 01 October 2009
View article titled, Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 <em>In vitro</em>
Open the PDF for Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 <em>In vitro</em> in another window
Includes: Supplementary data
Journal Articles

Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

William Matsui, Qiuju Wang, James P. Barber, Sarah Brennan, B. Douglas Smith, Ivan Borrello, Ian McNiece, Lan Lin, Richard F. Ambinder, Craig Peacock, D. Neil Watkins, Carol Ann Huff, Richard J. Jones
Journal: Cancer Research
Cancer Res (2008) 68 (1): 190–197.
https://doi.org/10.1158/0008-5472.CAN-07-3096
Published: 02 January 2008
View article titled, Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance
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Journal Articles

Apoptotic and anti-proliferative effects of the dual insulin-like growth factor-1 (IGF-1R)/insulin receptor inhibitor, BMS 536924, in acute myelogenous leukemia.

Andrea Wahner Hendrickson, Judith Karp, Joan Carboni, Ricardo Attar, B. Douglas Smith, Mark Whittman, Marco Gottardis, Paul Haluska, Scott Kaufmann
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2375.
Published: 01 May 2007
View article titled, Apoptotic and anti-proliferative effects of the dual insulin-like growth factor-1 (IGF-1R)/insulin receptor inhibitor, BMS 536924, in acute myelogenous leukemia.
Journal Articles

Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms

Steven D. Gore, Stephen Baylin, Elizabeth Sugar, Hetty Carraway, Carole B. Miller, Michael Carducci, Michael Grever, Oliver Galm, Tianna Dauses, Judith E. Karp, Michelle A. Rudek, Ming Zhao, B. Douglas Smith, Jasper Manning, Anchalee Jiemjit, George Dover, Abbie Mays, James Zwiebel, Anthony Murgo, Li-Jun Weng, James G. Herman
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6361–6369.
https://doi.org/10.1158/0008-5472.CAN-06-0080
Published: 15 June 2006
View article titled, Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms
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Journal Articles

The Myc Target Gene JPO1/CDCA7 Is Frequently Overexpressed in Human Tumors and Has Limited Transforming Activity In vivo

Rebecca C. Osthus, Baktiar Karim, Julia E. Prescott, B. Douglas Smith, Michael McDevitt, David L. Huso, Chi V. Dang
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5620–5627.
https://doi.org/10.1158/0008-5472.CAN-05-0536
Published: 01 July 2005
View article titled, The Myc Target Gene <em>JPO1/CDCA7</em> Is Frequently Overexpressed in Human Tumors and Has Limited Transforming Activity <em>In vivo</em>
Open the PDF for The Myc Target Gene <em>JPO1/CDCA7</em> Is Frequently Overexpressed in Human Tumors and Has Limited Transforming Activity <em>In vivo</em> in another window