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Journal Articles

Abstract 4382: Relative expression of miR200 microRNAs and ERBB family negative regulator Mig6 in estimation of EMT status and erlotinib sensitivity

Eugene G. Izumchenko, Xiaofei Chang, Christina Michailidi, Luciane Kagohara, Rajani Ravi, Mariana Brait, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4382.
https://doi.org/10.1158/1538-7445.AM2014-4382
Published: 01 October 2014
View article titled, Abstract 4382: Relative expression of miR200 microRNAs and ERBB family negative regulator Mig6 in estimation of EMT status and erlotinib sensitivity
Journal Articles

The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors

Evgeny Izumchenko, Xiaofei Chang, Christina Michailidi, Luciane Kagohara, Rajani Ravi, Keren Paz, Mariana Brait, Mohammad O. Hoque, Shizhang Ling, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2014) 74 (14): 3995–4005.
https://doi.org/10.1158/0008-5472.CAN-14-0110
Published: 14 July 2014
View article titled, The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
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Includes: Supplementary data
Journal Articles

Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib

Xiaofei Chang, Aditi Chatterjee, Shyhmin Huang, Myoung Sook Kim, Chunbo Shao, Constance L. Monitto, Patrick K. Ha, Manuel Hidalgo, Paul M. Harari, David M. Berman, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2703.
https://doi.org/10.1158/1538-7445.AM10-2703
Published: 15 April 2010
View article titled, Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib
Journal Articles

Abstract LB-25: Regulation of Np63α by IκB kinase-β

Aditi Chatterjee, Xiaofei Chang, Tanusree Sen, Rajani Ravi, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-25.
https://doi.org/10.1158/1538-7445.AM10-LB-25
Published: 15 April 2010
View article titled, Abstract LB-25: Regulation of Np63α by IκB kinase-β
Journal Articles

Regulation of p53 Family Member Isoform ΔNp63α by the Nuclear Factor-κB Targeting Kinase IκB Kinase β

Aditi Chatterjee, Xiaofei Chang, Tanusree Sen, Rajani Ravi, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (4): 1419–1429.
https://doi.org/10.1158/0008-5472.CAN-09-2613
Published: 14 February 2010
View article titled, Regulation of p53 Family Member Isoform ΔNp63α by the Nuclear Factor-κB Targeting Kinase IκB Kinase β
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Journal Articles

Resistance of Cancers to Immunologic Cytotoxicity and Adoptive Immunotherapy via X-Linked Inhibitor of Apoptosis Protein Expression and Coexisting Defects in Mitochondrial Death Signaling

Rajani Ravi, Ephraim J. Fuchs, Ajay Jain, Vui Pham, Kiyoshi Yoshimura, Traci Prouser, Sanju Jalla, Xianzheng Zhou, Elizabeth Garrett-Mayer, Scott H. Kaufmann, Richard D. Schulick, Drew M. Pardoll, Atul Bedi
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1730–1739.
https://doi.org/10.1158/0008-5472.CAN-05-3377
Published: 01 February 2006
View article titled, Resistance of Cancers to Immunologic Cytotoxicity and Adoptive Immunotherapy via X-Linked Inhibitor of Apoptosis Protein Expression and Coexisting Defects in Mitochondrial Death Signaling
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Journal Articles

Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL

Rajani Ravi, Ajay J. Jain, Richard D. Schulick, Vui Pham, Traci S. Prouser, Heather Allen, Elizabeth Garrett Mayer, Hua Yu, Drew M. Pardoll, Avi Ashkenazi, Atul Bedi
Journal: Cancer Research
Cancer Res (2004) 64 (24): 9105–9114.
https://doi.org/10.1158/0008-5472.CAN-04-2488
Published: 16 December 2004
View article titled, Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL
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Journal Articles

Sensitization of Tumor Cells to Apo2 Ligand/TRAIL-induced Apoptosis by Inhibition of Casein Kinase II

Rajani Ravi, Atul Bedi
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4180–4185.
Published: 01 August 2002
View article titled, Sensitization of Tumor Cells to Apo2 Ligand/TRAIL-induced Apoptosis by Inhibition of Casein Kinase II
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Journal Articles

Requirement of BAX for TRAIL/Apo2L-induced Apoptosis of Colorectal Cancers: Synergism with Sulindac-mediated Inhibition of Bcl-xL

Rajani Ravi, Atul Bedi
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1583–1587.
Published: 15 March 2002
View article titled, Requirement of <em>BAX</em> for TRAIL/Apo2L-induced Apoptosis of Colorectal Cancers: <subtitle>Synergism with Sulindac-mediated Inhibition of Bcl-x<sub>L</sub></subtitle>
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Journal Articles

Overexpression of a Dominant-Negative Signal Transducer and Activator of Transcription 3 Variant in Tumor Cells Leads to Production of SolubleFactors That Induce Apoptosis and Cell Cycle Arrest

Guilian Niu, Kenneth H. Shain, Mei Huang, Rajani Ravi, Atul Bedi, William S. Dalton, Richard Jove, Hua Yu
Journal: Cancer Research
Cancer Res (2001) 61 (8): 3276–3280.
Published: 15 April 2001
View article titled, Overexpression of a Dominant-Negative Signal Transducer and Activator of Transcription 3 Variant in Tumor Cells Leads to Production of SolubleFactors That Induce Apoptosis and Cell Cycle Arrest
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Journal Articles

p53-mediated Repression of Nuclear Factor-κB RelA via the Transcriptional Integrator p300

Rajani Ravi, Bijoyesh Mookerjee, Yvette van Hensbergen, Gauri C. Bedi, Antonio Giordano, Wafik S. El-Deiry, Ephraim J. Fuchs, Atul Bedi
Journal: Cancer Research
Cancer Res (1998) 58 (20): 4531–4536.
Published: 01 October 1998
View article titled, p53-mediated Repression of Nuclear Factor-κB RelA via the Transcriptional Integrator p300
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Journal Articles

CD95 (Fas)-induced Caspase-mediated Proteolysis of NF-κB

Rajani Ravi, Asheesh Bedi, Ephraim J. Fuchs, Atul Bedi
Journal: Cancer Research
Cancer Res (1998) 58 (5): 882–886.
Published: 01 March 1998
View article titled, CD95 (Fas)-induced Caspase-mediated Proteolysis of NF-κB
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Journal Articles

p53-dependent DNA Damage-induced Apoptosis Requires Fas/APO-1-independent Activation of CPP32β

Ephraim J. Fuchs, Karen A. McKenna, Atul Bedi
Journal: Cancer Research
Cancer Res (1997) 57 (13): 2550–2554.
Published: 01 July 1997
View article titled, p53-dependent DNA Damage-induced Apoptosis Requires Fas/APO-1-independent Activation of CPP32β
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Journal Articles

Requirement of p34cdc2 Kinase for Apoptosis Mediated by the Fas/APO-1 Receptor and Interleukin 1β-converting Enzyme-related Proteases

Siu-Long Yao, Karen A. McKenna, Saul J. Sharkis, Atul Bedi
Journal: Cancer Research
Cancer Res (1996) 56 (20): 4551–4555.
Published: 01 October 1996
View article titled, Requirement of p34<sup>cdc2</sup> Kinase for Apoptosis Mediated by the Fas/APO-1 Receptor and Interleukin 1β-converting Enzyme-related Proteases
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Journal Articles

Inhibition of Apoptosis during Development of Colorectal Cancer

Atul Bedi, Pankaj J. Pasricha, Adil J. Akhtar, James P. Barber, Gauri C. Bedi, Francis M. Giardiello, Barbara A. Zehnbauer, Stanley R. Hamilton, Richard J. Jones
Journal: Cancer Research
Cancer Res (1995) 55 (9): 1811–1816.
Published: 01 May 1995
View article titled, Inhibition of Apoptosis during Development of Colorectal Cancer
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Journal Articles

Cytotoxic T Cells Overcome BCR-ABL-mediated Resistance to Apoptosis

Ephraim J. Fuchs, Atul Bedi, Richard J. Jones, Allan D. Hess
Journal: Cancer Research
Cancer Res (1995) 55 (3): 463–466.
Published: 01 February 1995
View article titled, Cytotoxic T Cells Overcome BCR-ABL-mediated Resistance to Apoptosis
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Journal Articles

Growth Factor-mediated Terminal Differentiation of Chronic Myeloid Leukemia

Atul Bedi, Constance A. Griffin, James P. Barber, Milada S. Vala, Anita L. Hawkins, Saul J. Sharkis, Barbara A. Zehnbauer, Richard J. Jones
Journal: Cancer Research
Cancer Res (1994) 54 (21): 5535–5538.
Published: 01 November 1994
View article titled, Growth Factor-mediated Terminal Differentiation of Chronic Myeloid Leukemia
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