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Journal Articles

Abstract PR011: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Atique U. Ahmed, Jack M. Shireman, Fatemeh Atash, Gina Lee, Eunus S. Ali, Miranda R. Saathoff, Cheol H. Park, Sol Savchuk, Shivani Baisiwala, Jason Miska, Maciej S. Lesniak, C. David James, Roger Stupp, Priya Kumthekar, Craig M. Horbinski, Issam Ben-Sahra

Cancer Res (2022) 82 (10_Supplement): PR011.

https://doi.org/10.1158/1538-7445.EVODYN22-PR011

Published: 15 May 2022

View article titled, Abstract PR011: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Journal Articles

Abstract B034: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Cancer Res (2022) 82 (10_Supplement): B034.

https://doi.org/10.1158/1538-7445.EVODYN22-B034

Published: 15 May 2022

View article titled, Abstract B034: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Journal Articles

Abstract 197: Identifying a novel network of driver genes in glioblastoma

Shivani Baisiwala, Cheol Park, Chidibere Awah, Jack M. Shireman, Miranda R. Saathoff, Adam Sonabend, Atique U. Ahmed

Cancer Res (2020) 80 (16_Supplement): 197.

https://doi.org/10.1158/1538-7445.AM2020-197

Published: 15 August 2020

View article titled, Abstract 197: Identifying a novel network of driver genes in glioblastoma

Journal Articles

Abstract 83: The critical role of seven-in-absentia (SINA) family E3 ligases in normal development and oncogenic K-RAS-driven human cancer

Robert E. Van Sciver, Yajun Cao, Atique U. Ahmed, Amy H. Tang

Cancer Res (2019) 79 (13_Supplement): 83.

https://doi.org/10.1158/1538-7445.AM2019-83

Published: 01 July 2019

View article titled, Abstract 83: The critical role of seven-in-absentia (SINA) family E3 ligases in normal development and oncogenic K-RAS-driven human cancer

Journal Articles

Abstract 81: ARL13B interacts with IMPDH2 to modulate purine synthesis and temozolomide resistance in glioblastoma

Jack Shireman, Eunus Ali, Miranda Saathoff, Cheol Park, Issam Ben-Sahra, Atique U. Ahmed

Cancer Res (2019) 79 (13_Supplement): 81.

https://doi.org/10.1158/1538-7445.AM2019-81

Published: 01 July 2019

View article titled, Abstract 81: ARL13B interacts with IMPDH2 to modulate purine synthesis and temozolomide resistance in glioblastoma

Journal Articles

Abstract 4949: The role of symmetric cell division in post-therapy glioma-initiating cell expansion

Shivani Baisiwala, Robert Hall, Louisa Warnke, Anne Christensen, Jack Shireman, Cheol H. Park, Atique U. Ahmed

Cancer Res (2018) 78 (13_Supplement): 4949.

https://doi.org/10.1158/1538-7445.AM2018-4949

Published: 01 July 2018

View article titled, Abstract 4949: The role of symmetric cell division in post-therapy glioma-initiating cell expansion

Journal Articles

Abstract 2888: Dopamine signaling and therapeutic resistance in GBM

Seamus P. Caragher, Cheol H. Park, Fatemeh Atashi, Shivani Baisiwala, Atique U. Ahmed

Cancer Res (2017) 77 (13_Supplement): 2888.

https://doi.org/10.1158/1538-7445.AM2017-2888

Published: 01 July 2017

View article titled, Abstract 2888: Dopamine signaling and therapeutic resistance in GBM

Journal Articles

Abstract 4824: The “gatekeeper” function of Drosophila Seven-IN-Absentia (SINA) E3 ligase and its human homologs, SIAH1 and SIAH2, is highly conserved for proper RAS signal transduction in Drosophila development

Robert E. Van Sciver, Yajun Cao, Atique U. Ahmed, Amy H. Tang

Cancer Res (2017) 77 (13_Supplement): 4824.

https://doi.org/10.1158/1538-7445.AM2017-4824

Published: 01 July 2017

View article titled, Abstract 4824: The “gatekeeper” function of <em>Drosophila</em> Seven-IN-Absentia (SINA) E3 ligase and its human homologs, SIAH1 and SIAH2, is highly conserved for proper RAS signal transduction in <em>Drosophila</em> development

Journal Articles

CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

Alan L. Chang, Jason Miska, Derek A. Wainwright, Mahua Dey, Claudia V. Rivetta, Dou Yu, Deepak Kanojia, Katarzyna C. Pituch, Jian Qiao, Peter Pytel, Yu Han, Meijing Wu, Lingjiao Zhang, Craig M. Horbinski, Atique U. Ahmed, Maciej S. Lesniak

Cancer Res (2016) 76 (19): 5671–5682.

https://doi.org/10.1158/0008-5472.CAN-16-0144

Published: 02 October 2016

View article titled, CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

Includes: Supplementary data

Journal Articles

Abstract A1: SIAH E3 ligase as a novel anticancer drug target to inhibit RAS‐mediated tumorigenesis and metastasis in human cancer cells

Yang Liao, Cheol Hong Park, Rebecca L. Schmidt, Atique U. Ahmed, Rie Takahashi, Amy H. Tang

Cancer Res (2009) 69 (23_Supplement): A1.

https://doi.org/10.1158/0008-5472.FBCR09-A1

Published: 28 October 2014

View article titled, Abstract A1: SIAH E3 ligase as a novel anticancer drug target to inhibit RAS‐mediated tumorigenesis and metastasis in human cancer cells

Journal Articles

Abstract B14: Attacking the Achilles' heel in the oncogenic K-RAS signaling pathway to block tumorigenesis and metastasis in human cancers

Amy H. Tang, Yang Liao, Cheol Hong Park, Minglei Bian, Rebecca L. Schmidt, Atique U. Ahmed, Rie Takahashi, John A. Crooks, Zandra Walton

Cancer Res (2011) 71 (18_Supplement): B14.

https://doi.org/10.1158/1538-7445.FBCR11-B14

Published: 28 October 2014

View article titled, Abstract B14: Attacking the Achilles' heel in the oncogenic K-RAS signaling pathway to block tumorigenesis and metastasis in human cancers

Journal Articles

Abstract 3899: ROCK inhibitor as a differentiation-inducing agent to target glioma stem cells

Brenda Auffinger, Alex L. Tobias, Yu Han, Maciej S. Lesniak, Atique U. Ahmed

Cancer Res (2014) 74 (19_Supplement): 3899.

https://doi.org/10.1158/1538-7445.AM2014-3899

Published: 01 October 2014

View article titled, Abstract 3899: ROCK inhibitor as a differentiation-inducing agent to target glioma stem cells

Journal Articles

Abstract 5021: Temozolomide-induced conversion of glioma cells into glioma “stem-like” cells with enhanced invasion properties.

Atique U. Ahmed, Brenda Auffinger, Alex Tobias, Bart Thaci, Yu Han, Maciej S. Lesniak

Cancer Res (2013) 73 (8_Supplement): 5021.

https://doi.org/10.1158/1538-7445.AM2013-5021

Published: 15 April 2013

View article titled, Abstract 5021: Temozolomide-induced conversion of glioma cells into glioma “stem-like” cells with enhanced invasion properties.

Journal Articles

Abstract 3487: Distant delivery of glioma-restricted oncolytic adenovirus loaded into a neural stem cell-based carrier prolongs the survival of animals with human glioblastoma

Atique U. Ahmed, Bart Thaci, Alex Tobias, Nikita G. Alexiades, Yu Han, Ilya I. Ulasov, Karen Aboody, Maciej S. Lesniak

Cancer Res (2012) 72 (8_Supplement): 3487.

https://doi.org/10.1158/1538-7445.AM2012-3487

Published: 15 April 2012

View article titled, Abstract 3487: Distant delivery of glioma-restricted oncolytic adenovirus loaded into a neural stem cell-based carrier prolongs the survival of animals with human glioblastoma

Journal Articles

Abstract 1659: Targeting SIAH2-dependent proteolysis downstream of the HER2/EGFR/RAS signaling pathway to inhibit tumorigenesis and metastasis of highly invasive human breast cancer

Cheol Hong Park, Yang Liao, Atique U. Ahmed, Nanette R. Reed, Shayla E. Hesse, Wilma L. Lingle, Rafael E. Jimenez, Amy H. Tang

Cancer Res (2011) 71 (8_Supplement): 1659.

https://doi.org/10.1158/1538-7445.AM2011-1659

Published: 15 April 2011

View article titled, Abstract 1659: Targeting SIAH2-dependent proteolysis downstream of the HER2/EGFR/RAS signaling pathway to inhibit tumorigenesis and metastasis of highly invasive human breast cancer

Journal Articles

Abstract 4518: Targeting SIAH2 E3 ligase to inhibit HER2/EGFR/RAS activation and to block tumorigenesis and metastasis of highly invasive human breast cancer cells

Cheol Hong Park, Yang Liao, Atique U. Ahmed, Nanette R. Reed, Shayla E. Hesse, Wilma L. Lingle, Rafael E. Jimenez, Amy H. Tang

Cancer Res (2010) 70 (8_Supplement): 4518.

https://doi.org/10.1158/1538-7445.AM10-4518

Published: 15 April 2010

View article titled, Abstract 4518: Targeting SIAH2 E3 ligase to inhibit HER2/EGFR/RAS activation and to block tumorigenesis and metastasis of highly invasive human breast cancer cells

Journal Articles

Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue

Rebecca L. Schmidt, Cheol Hong Park, Atique U. Ahmed, Justin H. Gundelach, Nanette R. Reed, Shen Cheng, Bruce E. Knudsen, Amy H. Tang

Cancer Res (2007) 67 (24): 11798–11810.

https://doi.org/10.1158/0008-5472.CAN-06-4471

Published: 18 December 2007

View article titled, Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue

Includes: Supplementary data

NARROW

Abstract PR011: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Abstract B034: Targeting cellular plasticity-driven metabolic adaptation to overcome chemoresistance in GBM

Abstract 197: Identifying a novel network of driver genes in glioblastoma

Abstract 83: The critical role of seven-in-absentia (SINA) family E3 ligases in normal development and oncogenic K-RAS-driven human cancer

Abstract 81: ARL13B interacts with IMPDH2 to modulate purine synthesis and temozolomide resistance in glioblastoma

Abstract 4949: The role of symmetric cell division in post-therapy glioma-initiating cell expansion

Abstract 2888: Dopamine signaling and therapeutic resistance in GBM

Abstract 4824: The “gatekeeper” function of Drosophila Seven-IN-Absentia (SINA) E3 ligase and its human homologs, SIAH1 and SIAH2, is highly conserved for proper RAS signal transduction in Drosophila development

CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

Abstract A1: SIAH E3 ligase as a novel anticancer drug target to inhibit RAS‐mediated tumorigenesis and metastasis in human cancer cells

Abstract B14: Attacking the Achilles' heel in the oncogenic K-RAS signaling pathway to block tumorigenesis and metastasis in human cancers

Abstract 3899: ROCK inhibitor as a differentiation-inducing agent to target glioma stem cells

Abstract 5021: Temozolomide-induced conversion of glioma cells into glioma “stem-like” cells with enhanced invasion properties.

Abstract 3487: Distant delivery of glioma-restricted oncolytic adenovirus loaded into a neural stem cell-based carrier prolongs the survival of animals with human glioblastoma

Abstract 1659: Targeting SIAH2-dependent proteolysis downstream of the HER2/EGFR/RAS signaling pathway to inhibit tumorigenesis and metastasis of highly invasive human breast cancer

Abstract 4518: Targeting SIAH2 E3 ligase to inhibit HER2/EGFR/RAS activation and to block tumorigenesis and metastasis of highly invasive human breast cancer cells

Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue

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