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Atanasio Pandiella
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Journal Articles

Therapy-Induced Senescence Enhances the Efficacy of HER2-Targeted Antibody–Drug Conjugates in Breast Cancer

Santiago Duro-Sánchez, Mercedes Nadal-Serrano, Marta Lalinde-Gutiérrez, Enrique Javier Arenas, Cristina Bernadó Morales, Beatriz Morancho, Marta Escorihuela, Sandra Pérez-Ramos, Santiago Escrivá-de-Romaní, Lucía Gandullo-Sánchez, Atanasio Pandiella, Anna Esteve-Codina, Verónica Rodilla, Fred A. Dijcks, Wim H.A. Dokter, Javier Cortés, Cristina Saura, Joaquín Arribas
Journal: Cancer Research
Cancer Res (2022) 82 (24): 4670–4679.
https://doi.org/10.1158/0008-5472.CAN-22-0787
Published: 16 December 2022
View articletitled, Therapy-Induced Senescence Enhances the Efficacy of HER2-Targeted Antibody–Drug Conjugates in Breast Cancer
Open the PDF for Therapy-Induced Senescence Enhances the Efficacy of HER2-Targeted Antibody–Drug Conjugates in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21

Alessandro Tubita, Zoe Lombardi, Ignazia Tusa, Azzurra Lazzeretti, Giovanna Sgrignani, Dimitri Papini, Alessio Menconi, Sinforosa Gagliardi, Matteo Lulli, Persio Dello Sbarba, Azucena Esparís-Ogando, Atanasio Pandiella, Barbara Stecca, Elisabetta Rovida
Journal: Cancer Research
Cancer Res (2022) 82 (3): 447–457.
https://doi.org/10.1158/0008-5472.CAN-21-0993
Published: 01 February 2022
View articletitled, Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21
Open the PDF for Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21 in another window
Includes: Supplementary data
Journal Articles

Abstract P4-10-11: PIK3CA status as a predictor of benefit from drugs targeting the PI3K/AKT/mTOR pathway: A meta-analysis of randomized trials

Fahad A Almugbel, Ramy Saleh, Alberto Ocana, Atanasio Pandiella, Eitan Amir
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-10-11.
https://doi.org/10.1158/1538-7445.SABCS19-P4-10-11
Published: 15 February 2020
View articletitled, Abstract P4-10-11: PIK3CA status as a predictor of benefit from drugs targeting the PI3K/AKT/mTOR pathway: A meta-analysis of randomized trials
Journal Articles

Abstract 1608: Pharmacologic screening identifies synthetic lethality interactions with Chk1 inhibitors in basal-like breast and ovarian cancer

Eva M. Galan-Moya, Ana Alcaraz-Sanabria, Cristina Nieto-Jimenez, Veronica Corrales-Sanchez, Miriam Nuncia-Cantarero, Juan C. Montero, Atanasio Pandiella, Alberto Ocaña
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1608.
https://doi.org/10.1158/1538-7445.AM2018-1608
Published: 01 July 2018
View articletitled, Abstract 1608: Pharmacologic screening identifies synthetic lethality interactions with Chk1 inhibitors in basal-like breast and ovarian cancer
Journal Articles

Abstract 741: Targeting trastuzumab and T-DM-1 resistant breast cancer cells with EV20/MMAF, an antibody drug-conjugate against HER3

Gianluca Sala, Lucia Gandullo, Emily Capone, Maria Elena Diaz-Rodriguez, Daniela D'Agostino, Vincenzo De Laurenzi, Jean-Frederic Sauniere, Stefano Iacobelli, Atanasio Pandiella
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 741.
https://doi.org/10.1158/1538-7445.AM2018-741
Published: 01 July 2018
View articletitled, Abstract 741: Targeting trastuzumab and T-DM-1 resistant breast cancer cells with EV20/MMAF, an antibody drug-conjugate against HER3
Journal Articles

Resistance to Antibody–Drug Conjugates

Sara García-Alonso, Alberto Ocaña, Atanasio Pandiella
Journal: Cancer Research
Cancer Res (2018) 78 (9): 2159–2165.
https://doi.org/10.1158/0008-5472.CAN-17-3671
Published: 30 April 2018
View articletitled, Resistance to Antibody–Drug Conjugates
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Journal Articles

Resistance to the Antibody–Drug Conjugate T-DM1 Is Based in a Reduction in Lysosomal Proteolytic Activity

Carla Ríos-Luci, Sara García-Alonso, Elena Díaz-Rodríguez, Mercedes Nadal-Serrano, Joaquín Arribas, Alberto Ocaña, Atanasio Pandiella
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4639–4651.
https://doi.org/10.1158/0008-5472.CAN-16-3127
Published: 31 August 2017
View articletitled, Resistance to the Antibody–Drug Conjugate T-DM1 Is Based in a Reduction in Lysosomal Proteolytic Activity
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2830: Multikinase inhibition by TG02 is therapeutically effective in two forms of breast cancer

M Jesús Ortiz-Ruiz, Francis J. Burrows, M Florencia Ré-Louhau, Alberto Ocaña, Atanasio Pandiella, Azucena Esparís-Ogando
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2830.
https://doi.org/10.1158/1538-7445.AM2012-2830
Published: 15 April 2012
View articletitled, Abstract 2830: Multikinase inhibition by TG02 is therapeutically effective in two forms of breast cancer
Journal Articles

Aplidin, a Marine Organism–Derived Compound with Potent Antimyeloma Activity In vitro and In vivo

Constantine S. Mitsiades, Enrique M. Ocio, Atanasio Pandiella, Patricia Maiso, Consuelo Gajate, Mercedes Garayoa, David Vilanova, Juan Carlos Montero, Nicholas Mitsiades, Ciaran J. McMullan, Nikhil C. Munshi, Teru Hideshima, Dharminder Chauhan, Pablo Aviles, Gabriel Otero, Glynn Faircloth, M. Victoria Mateos, Paul G. Richardson, Faustino Mollinedo, Jesus F. San-Miguel, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5216–5225.
https://doi.org/10.1158/0008-5472.CAN-07-5725
Published: 01 July 2008
View articletitled, Aplidin, a Marine Organism–Derived Compound with Potent Antimyeloma Activity In vitro and In vivo
Open the PDF for Aplidin, a Marine Organism–Derived Compound with Potent Antimyeloma Activity In vitro and In vivo in another window
Includes: Supplementary data
Journal Articles

The Histone Deacetylase Inhibitor LBH589 Is a Potent Antimyeloma Agent that Overcomes Drug Resistance

Patricia Maiso, Xonia Carvajal-Vergara, Enrique M. Ocio, Ricardo López-Pérez, Gema Mateo, Norma Gutiérrez, Peter Atadja, Atanasio Pandiella, Jesús F. San Miguel
Journal: Cancer Research
Cancer Res (2006) 66 (11): 5781–5789.
https://doi.org/10.1158/0008-5472.CAN-05-4186
Published: 01 June 2006
View articletitled, The Histone Deacetylase Inhibitor LBH589 Is a Potent Antimyeloma Agent that Overcomes Drug Resistance
Open the PDF for The Histone Deacetylase Inhibitor LBH589 Is a Potent Antimyeloma Agent that Overcomes Drug Resistance in another window
Journal Articles

Activation of ErbB2 by Overexpression or by Transmembrane Neuregulin Results in Differential Signaling and Sensitivity to Herceptin

Laura Yuste, Juan C. Montero, Azucena Esparís-Ogando, Atanasio Pandiella
Journal: Cancer Research
Cancer Res (2005) 65 (15): 6801–6810.
https://doi.org/10.1158/0008-5472.CAN-04-4023
Published: 01 August 2005
View articletitled, Activation of ErbB2 by Overexpression or by Transmembrane Neuregulin Results in Differential Signaling and Sensitivity to Herceptin
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Journal Articles

Voltage-operated Calcium Channels in Small Cell Lung Carcinoma Cell Lines: Pharmacological, Functional, and Immunological Properties

Emanuele Sher, Atanasio Pandiella, Francesco Clementi
Journal: Cancer Research
Cancer Res (1990) 50 (13): 3892–3896.
Published: 01 July 1990
View articletitled, Voltage-operated Calcium Channels in Small Cell Lung Carcinoma Cell Lines: Pharmacological, Functional, and Immunological Properties
Open the PDF for Voltage-operated Calcium Channels in Small Cell Lung Carcinoma Cell Lines: Pharmacological, Functional, and Immunological Properties in another window