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Asha S. Multani
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Journal Articles

Low–Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer

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Mi Li, Amriti R. Lulla, Yan Wang, Spyros Tsavaschidis, Fuchenchu Wang, Cansu Karakas, Tuyen D.T. Nguyen, Tuyen N. Bui, Marc A. Pina, Mei-Kuang Chen, Sofia Mastoraki, Asha S. Multani, Natalie W. Fowlkes, Aysegul Sahin, C. Gary Marshall, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2024) 84 (22): 3864–3880.
https://doi.org/10.1158/0008-5472.CAN-23-4130
Published: 15 November 2024
View articletitled, Low–Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer
Open the PDF for Low–Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 308: Low molecular weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer

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Mi Li, Spiridon Tsavachidis, Fuchenchu Wang, Tuyen Bui, Tuyen D. Nguyen, Linjie Luo, Asha S. Multani, Melissa L. Bondy, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 308.
https://doi.org/10.1158/1538-7445.AM2023-308
Published: 04 April 2023
View articletitled, Abstract 308: Low molecular weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer
Journal Articles

Abstract 2585: Mutant p53 gains oncogenic functions through a cytosolic DNA response

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Mei Zhao, Tianxiao Wang, Frederico O. Gleber-Netto, Zhen Chen, Daniel J. McGrail, Javier A. Gomez, Wutong Ju, Mayur A. Gadhikar, Wencai Ma, Li Shen, Ximing Tang, Sen Pathak, Maria G. Raso, Jared Burks, Shiaw-Yih Lin, Jing Wang, Asha S. Multani, Curtis R. Pickering, Junjie Chen, Jeffrey N. Myers, Ge Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2585.
https://doi.org/10.1158/1538-7445.AM2023-2585
Published: 04 April 2023
View articletitled, Abstract 2585: Mutant p53 gains oncogenic functions through a cytosolic DNA response
Journal Articles

Abstract 1186: Patient-derived breast cancer xenografts demonstrate molecular evolution in the phosphatidylinositol 3-kinase pathway upon engraftment

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Priscilla F. McAuliffe, Argun Akcakanat, Kurt Evans, Agda Karina Eterovic, Hao Zhao, Ken Chen, Takafumi Sangai, Huiqin Chen, Kim-Anh Do, Ashley M. Holder, Chandeshwar Sharma, William Fraser Symmans, Mihai Gagea, Katherine A. Naff, Aysegul Sahin, Asha S. Multani, Gordon B. Mills, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1186.
https://doi.org/10.1158/1538-7445.AM2014-1186
Published: 01 October 2014
View articletitled, Abstract 1186: Patient-derived breast cancer xenografts demonstrate molecular evolution in the phosphatidylinositol 3-kinase pathway upon engraftment
Journal Articles

Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis

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Shian-Ying Sung, Chia-Ling Hsieh, Andrew Law, Haiyen E. Zhau, Sen Pathak, Asha S. Multani, Sharon Lim, Ilsa M. Coleman, Li-Chin Wu, William D. Figg, William L. Dahut, Peter Nelson, Jae K. Lee, Mahul B. Amin, Robert Lyles, Peter A.J. Johnstone, Fray F. Marshall, Leland W.K. Chung
Journal: Cancer Research
Cancer Res (2008) 68 (23): 9996–10003.
https://doi.org/10.1158/0008-5472.CAN-08-2492
Published: 01 December 2008
View articletitled, Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis
Open the PDF for Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Overexpression of the Low Molecular Weight Cyclin E in Transgenic Mice Induces Metastatic Mammary Carcinomas through the Disruption of the ARF-p53 Pathway

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Said Akli, Carolyn S. Van Pelt, Tuyen Bui, Asha S. Multani, Sandy Chang, David Johnson, Susan Tucker, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2007) 67 (15): 7212–7222.
https://doi.org/10.1158/0008-5472.CAN-07-0599
Published: 01 August 2007
View articletitled, Overexpression of the Low Molecular Weight Cyclin E in Transgenic Mice Induces Metastatic Mammary Carcinomas through the Disruption of the ARF-p53 Pathway
Open the PDF for Overexpression of the Low Molecular Weight Cyclin E in Transgenic Mice Induces Metastatic Mammary Carcinomas through the Disruption of the ARF-p53 Pathway in another window
Includes: Supplementary data
Journal Articles

Low molecular weight Cyclin E is a much stronger oncogene in breast cancer tumorigenesis than full length Cyclin E in transgenic mice

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Said Akli, Carolyn S. Van Pelt, Tuyen Bui, Guillermina Lozano, David Johnson, Asha S. Multani, Sandy Chang, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 420.
Published: 15 April 2006
View articletitled, Low molecular weight Cyclin E is a much stronger oncogene in breast cancer tumorigenesis than full length Cyclin E in transgenic mice
Journal Articles

Tumor-Specific Low Molecular Weight Forms of Cyclin E Induce Genomic Instability and Resistance to p21, p27, and Antiestrogens in Breast Cancer

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Said Akli, Ping-Ju Zheng, Asha S. Multani, Hannah F. Wingate, Sen Pathak, Ning Zhang, Susan L. Tucker, Sandy Chang, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2004) 64 (9): 3198–3208.
https://doi.org/10.1158/0008-5472.CAN-03-3672
Published: 03 May 2004
View articletitled, Tumor-Specific Low Molecular Weight Forms of Cyclin E Induce Genomic Instability and Resistance to p21, p27, and Antiestrogens in Breast Cancer
Open the PDF for Tumor-Specific Low Molecular Weight Forms of Cyclin E Induce Genomic Instability and Resistance to p21, p27, and Antiestrogens in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

N-methyl-N’-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with the loss of adenomatous polyposis coli protein, microtubule organization and telomeric DNA

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Aruna S. Jaiswal, Asha S. Multani, Sen Pathak, Satya Narayan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1169.
Published: 01 April 2004
View articletitled, N-methyl-N’-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with the loss of adenomatous polyposis coli protein, microtubule organization and telomeric DNA
Journal Articles

Molecular Characterization of New Melanoma Cell Lines from C3H Mice Induced by Ethanol plus Ultraviolet Radiation

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Faith M. Strickland, Sen Pathak, Asha S. Multani, Ronald P. Pelley, Cherrie K. Donawho
Journal: Cancer Research
Cancer Res (2003) 63 (13): 3503–3510.
Published: 01 July 2003
View articletitled, Molecular Characterization of New Melanoma Cell Lines from C3H Mice Induced by Ethanol plus Ultraviolet Radiation
Open the PDF for Molecular Characterization of New Melanoma Cell Lines from C3H Mice Induced by Ethanol plus Ultraviolet Radiation in another window
Journal Articles

Adenoviral-mediated Retinoblastoma 94 Produces Rapid Telomere Erosion, Chromosomal Crisis, and Caspase-dependent Apoptosis in Bladder Cancer and Immortalized Human Urothelial Cells but not in Normal Urothelial Cells

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Xinqiao Zhang, Asha S. Multani, Jain-Hua Zhou, Jerry W. Shay, David McConkey, Li Dong, Chang-Soo Kim, Charles J. Rosser, Sen Pathak, William F. Benedict
Journal: Cancer Research
Cancer Res (2003) 63 (4): 760–765.
Published: 15 February 2003
View articletitled, Adenoviral-mediated Retinoblastoma 94 Produces Rapid Telomere Erosion, Chromosomal Crisis, and Caspase-dependent Apoptosis in Bladder Cancer and Immortalized Human Urothelial Cells but not in Normal Urothelial Cells
Open the PDF for Adenoviral-mediated Retinoblastoma 94 Produces Rapid Telomere Erosion, Chromosomal Crisis, and Caspase-dependent Apoptosis in Bladder Cancer and Immortalized Human Urothelial Cells but not in Normal Urothelial Cells in another window
Journal Articles

Low-Level c-myc Amplification in Human Colonic Carcinoma Cell Lines and Tumors: A Frequent, p53-independent Mutation Associated with Improved Outcome in a Randomized Multi-institutional Trial

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Leonard H. Augenlicht, Scott Wadler, Georgia Corner, Christine Richards, Louise Ryan, Asha S. Multani, Sen Pathak, Al Benson, Daniel Haller, Barbara G. Heerdt
Journal: Cancer Research
Cancer Res (1997) 57 (9): 1769–1775.
Published: 01 May 1997
View articletitled, Low-Level c-myc Amplification in Human Colonic Carcinoma Cell Lines and Tumors: A Frequent, p53-independent Mutation Associated with Improved Outcome in a Randomized Multi-institutional Trial
Open the PDF for Low-Level c-myc Amplification in Human Colonic Carcinoma Cell Lines and Tumors: A Frequent, p53-independent Mutation Associated with Improved Outcome in a Randomized Multi-institutional Trial in another window