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Arunasalam Navaraj
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Journal Articles

Abstract 4185: Inclusive basic and advanced translational laboratory research competencies for research in cancer biology and therapeutics

Free
Wafik S. El-Deiry, Andrew George, Francesca Di Cristofano, Praveen Srinivasan, Lindsey Carlsen, Kelsey E. Huntington, Arielle De La Cruz, Leiqing Zhang, Marina Hahn, Shuai Zhao, Attila Seyhan, Bradley D. DeNardo, Aaron W. Maxwell, Dae Hee Kim, Alex Raufi, Hina Khan, Stephanie L. Graff, Don S. Dizon, Christopher Azzoli, Abbas E. Abbas, Roxanne Wood, Rishi R. Lulla, Howard P. Safran, Benedito A. Carneiro, Arunasalam Navaraj, Xiaobing Tian, Shengliang Zhang, Lanlan Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4185.
https://doi.org/10.1158/1538-7445.AM2023-4185
Published: 04 April 2023
View articletitled, Abstract 4185: Inclusive basic and advanced translational laboratory research competencies for research in cancer biology and therapeutics
Journal Articles

Abstract 2373: Combination treatment with pH modulating drugs and immune checkpoint inhibitors increases TALL-104 cytotoxicity in preclinical co-culture experiments

Free
Ryan Malpass, Kelsey E. Huntington, Thomas Brown, Lanlan Zhou, Leiqing Zhang, Arunasalam Navaraj, Wafik S. El-Deiry, Aaron Maxwell
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2373.
https://doi.org/10.1158/1538-7445.AM2023-2373
Published: 04 April 2023
View articletitled, Abstract 2373: Combination treatment with pH modulating drugs and immune checkpoint inhibitors increases TALL-104 cytotoxicity in preclinical co-culture experiments
Journal Articles

Abstract 6706: Co-culture of circulating tumor cells (CTCs)-derived 3D organoids and autologous cytotoxic CD8+ T cells: A new functional precision oncology platform

Free
Lanlan Zhou, Leiqing Zhang, Lindsey Carlsen, Kelsey E. Huntington, Vida Tajiknia, Andrew George, Arielle De La Cruz, Arunasalam Navaraj, Praveen Srinivasan, Maximilian Schwermann, Benedito A. Carneiro, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6706.
https://doi.org/10.1158/1538-7445.AM2023-6706
Published: 04 April 2023
View articletitled, Abstract 6706: Co-culture of circulating tumor cells (CTCs)-derived 3D organoids and autologous cytotoxic CD8+ T cells: A new functional precision oncology platform
Journal Articles

Abstract 999: The transcriptional response in colorectal cancer cells varies across four clinically used chemotherapeutic drugs in terms of gene identity, magnitude of change, and p53 dependence

Free
Lindsey Carlsen, Lanlan Zhou, Liz J. Hernández Borrero, Arunasalam Navaraj, Shengliang Zhang, Christoph Schorl, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 999.
https://doi.org/10.1158/1538-7445.AM2021-999
Published: 01 July 2021
View articletitled, Abstract 999: The transcriptional response in colorectal cancer cells varies across four clinically used chemotherapeutic drugs in terms of gene identity, magnitude of change, and p53 dependence
Journal Articles

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity

Free
Niklas K. Finnberg, Prashanth Gokare, Arunasalam Navaraj, Krystle A. Lang Kuhs, George Cerniglia, Hideo Yagita, Kazuyoshi Takeda, Noboru Motoyama, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2016) 76 (3): 700–712.
https://doi.org/10.1158/0008-5472.CAN-15-2759
Published: 31 January 2016
View articletitled, Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity
Open the PDF for Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity in another window
Includes: Supplementary data
Journal Articles

Abstract 2926: DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)

Free
Niklas K. Finnberg, Prashanth Gokare, Arunasalam Navaraj, Krystle A. Lang Kuhs, George Cerniglia, Hideo Yagita, Kazuyoshi Takeda, Noboru Motoyama, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2926.
https://doi.org/10.1158/1538-7445.AM2015-2926
Published: 01 August 2015
View articletitled, Abstract 2926: DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)
Journal Articles

Abstract 1170: Anti-tumor effects of p53-pathway restoring compound Prodigiosin in colorectal cancer involve effects on apoptotic signaling, angiogenesis and cancer stem cells

Free
Varun Vijay Prabhu, Bo Hong, Joshua E. Allen, David T. Dicker, Arunasalam Navaraj, Levy Kopelovich, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1170.
https://doi.org/10.1158/1538-7445.AM2012-1170
Published: 15 April 2012
View articletitled, Abstract 1170: Anti-tumor effects of p53-pathway restoring compound Prodigiosin in colorectal cancer involve effects on apoptotic signaling, angiogenesis and cancer stem cells
Journal Articles

Abstract 1400: Mouse models for detection of circulating tumor cells from breast cancer

Free
Arunasalam Navaraj, David T. Dicker, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1400.
https://doi.org/10.1158/1538-7445.AM2012-1400
Published: 15 April 2012
View articletitled, Abstract 1400: Mouse models for detection of circulating tumor cells from breast cancer
Journal Articles

Abstract 5665: Multiplexing markers of response to sorafenib/mapatumumab combination therapy in hepatocellular carcinoma circulating tumor cells

Free
Nathan G. Dolloff, Lanlan Zhou, Kristi Peters, Arunasalam Navaraj, Joshua Allen, Avisnata Das, David Dicker, Wafik El-Deiry
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5665.
https://doi.org/10.1158/1538-7445.AM2012-5665
Published: 15 April 2012
View articletitled, Abstract 5665: Multiplexing markers of response to sorafenib/mapatumumab combination therapy in hepatocellular carcinoma circulating tumor cells
Journal Articles

Abstract LB-57: Multiplexed detection of phospho-ERK as a marker of H-Ras signaling, EGFR and cancer stem cell marker expression in breast cancer cells recovered from human blood

Free
Arunasalam Navaraj, David T. Dicker, Nathan Dolloff, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-57.
https://doi.org/10.1158/1538-7445.AM2011-LB-57
Published: 15 April 2011
View articletitled, Abstract LB-57: Multiplexed detection of phospho-ERK as a marker of H-Ras signaling, EGFR and cancer stem cell marker expression in breast cancer cells recovered from human blood
Journal Articles

Abstract #618: The role of DNA damage-inducible Polo-like kinase 2 as a tumor suppressor and target for therapy.

Free
Elizabeth Matthew, Lori Hart, Aristotelis Astrinidis, Arunasalam Navaraj, Nathan Dolloff, Wafik El-Deiry
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 618.
Published: 01 May 2009
View articletitled, Abstract #618: The role of DNA damage-inducible Polo-like kinase 2 as a tumor suppressor and target for therapy.
Journal Articles

Molecular imaging of p53 mRNA

Free
Xiaobing Tian, Wensheng Yang, Arunasalam Navaraj, Wafik El-Deiry
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3177.
Published: 01 May 2008
View articletitled, Molecular imaging of p53 mRNA
Journal Articles

Characterization of EMT and in vivo bio-imaging of transformed mammary epithelial cells with H-Ras over-expression and BRCA1 siRNA knockdown

Free
Arunasalam Navaraj, Wafik El-Deiry
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5231.
Published: 01 May 2008
View articletitled, Characterization of EMT and in vivo bio-imaging of transformed mammary epithelial cells with H-Ras over-expression and BRCA1 siRNA knockdown
Journal Articles

Enhanced H-Ras-mediated transformation of human mammary epithelial cells following BRCA1 knockdown is associated with elevated cyclin D1, c-myc and ER-alpha

Free
Arunasalam Navaraj, Wafik S.El-Deiry
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4534.
Published: 01 May 2007
View articletitled, Enhanced H-Ras-mediated transformation of human mammary epithelial cells following BRCA1 knockdown is associated with elevated cyclin D1, c-myc and ER-alpha
Journal Articles

Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras

Free
Seok-Hyun Kim, Hiroshi Nakagawa, Arunasalam Navaraj, Yoshio Naomoto, Andres J.P. Klein-Szanto, Anil K. Rustgi, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10415–10424.
https://doi.org/10.1158/0008-5472.CAN-06-2104
Published: 01 November 2006
View articletitled, Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras
Open the PDF for Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras in another window
Includes: Supplementary data
Journal Articles

Transformation of DNA repair-deficient XPC fibroblasts and mammary epithelial cells with BRCA1 siRNA knockdown

Free
Arunasalam Navaraj, David T. Dicker, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 777.
Published: 15 April 2006
View articletitled, Transformation of DNA repair-deficient XPC fibroblasts and mammary epithelial cells with BRCA1 siRNA knockdown
Journal Articles

Transformation of DNA repair-deficient fibroblasts and mammary epithelial cells with or without BRCA1 knockdown

Free
Arunasalam Navaraj, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 674.
Published: 01 May 2005
View articletitled, Transformation of DNA repair-deficient fibroblasts and mammary epithelial cells with or without BRCA1 knockdown
Journal Articles

Cooperation between p53 and BRCA1 in repair of cyclobutane pyrimidine dimers but not (6-4) photoproducts following UV exposure of human breast cancer cells.

Free
Arunasalam Navaraj, Wafik S. el-Deiry
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 811.
Published: 01 April 2004
View articletitled, Cooperation between p53 and BRCA1 in repair of cyclobutane pyrimidine dimers but not (6-4) photoproducts following UV exposure of human breast cancer cells.