1-20 of 147
Arul M. Chinnaiyan
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract C033: Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Caleb Cheng, Jasmine P Wisniewski, Sydney Peters, Jing Hu, Rahul Mannan, Bailey Jackson, Rüya Pakkan, Pietro Morlacchi, Brian Magnuson, Tongchen He, Rupam Bhattacharyya, Yuanyuan Qiao, Costas A Lyssiotis, Arul M Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): C033.
https://doi.org/10.1158/1538-7445.PANCREATIC24-C033
Published: 15 September 2024
View articletitled, Abstract C033: Targeting PIKfyve-driven lipid metabolism in pancreatic cancer
Journal Articles

Abstract PR-14: Meta-analysis of spatial transcriptomics data from pancreatic cancer precursors proposes a common molecular framework for PanIN and IPMN

Matthew K Iyer, Ashley Fletcher, Elishama Kanu, Chanjuan Shi, Rosina Carr, Ahmed M. Elhossiny, Daniel P. Nussbaum, Eileen S. Carpenter, Marina Pasca di Magliano, Arul M. Chinnaiyan, Peter J. Allen, Timothy L. Frankel
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): PR-14.
https://doi.org/10.1158/1538-7445.PANCREATIC24-PR-14
Published: 15 September 2024
View articletitled, Abstract PR-14: Meta-analysis of spatial transcriptomics data from pancreatic cancer precursors proposes a common molecular framework for PanIN and IPMN
Journal Articles

Abstract 2087: Targeting lipid metabolism in pancreatic cancer

Caleb Cheng, Jasmine P. Wisniewski, Ahmet Korkaya, Bailey Jackson, Rahul Mannan, Somnath Mahapatra, Nicholas Rossiter, Rupam Bhattacharyya, Pietro Morlacchi, Sydney Peters, Yuanyuan Qiao, Costas A. Lyssiotis, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2087.
https://doi.org/10.1158/1538-7445.AM2024-2087
Published: 22 March 2024
View articletitled, Abstract 2087: Targeting lipid metabolism in pancreatic cancer
Journal Articles

Abstract 1433: FOXA1 alterations distinctively drive prostate tumorigenesis or therapy resistance in mice

Sanjana Eyunni, Abhijit Parolia, Eleanor Young, James Matthew George, Rahul Mannan, Sandra E. Carson, Yuping Zhang, Jean Tien, Mustapha Jaber, Jie Luo, Matthew Pang, Rohit Mehra, Xuhong Cao, Fengyun Su, Rui Wang, Marcin Cieslik, Dong Kee Lee, Jianming Xu, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1433.
https://doi.org/10.1158/1538-7445.AM2024-1433
Published: 22 March 2024
View articletitled, Abstract 1433: FOXA1 alterations distinctively drive prostate tumorigenesis or therapy resistance in mice
Journal Articles

Abstract 3299: Harnessing PIKfyve as a therapeutic vulnerability in neuroendocrine prostate cancer

Yang Zheng, Kyle Garcia Rogers, Arya Gopal Kamat, Sarah Nicole Yee, Rahul Mannan, Xia Jiang, Rowena Kannaiyan, Xuhong Cao, Yuzhuo Wang, Yuanyuan Qiao, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3299.
https://doi.org/10.1158/1538-7445.AM2024-3299
Published: 22 March 2024
View articletitled, Abstract 3299: Harnessing PIKfyve as a therapeutic vulnerability in neuroendocrine prostate cancer
Journal Articles

Abstract 5217: Genome instability in renal tumors

Hanbyul Cho, Ginny X. Li, Rahul Mannan, Noshad Hosseini, Yi Hsiao, Yuping Zhang, Aniket Dagar, Chandan Kumar-Sinha, Marcin P. Cieslik, Saravana M. Dhanasekaran, Alexey I. Nesvizhskii, Arul M. Chinnaiyan, Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5217.
https://doi.org/10.1158/1538-7445.AM2024-5217
Published: 22 March 2024
View articletitled, Abstract 5217: Genome instability in renal tumors
Journal Articles

Abstract 4323: Deletion of the lipid kinase PIKfyve in Kras-driven pancreatic genetically engineered mouse model

Sarah N. Yee, Xia Jiang, Caleb Cheng, Ahmet Korkaya, Rahul Mannan, Rohit Mehra, Yuanyuan Qiao, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4323.
https://doi.org/10.1158/1538-7445.AM2024-4323
Published: 22 March 2024
View articletitled, Abstract 4323: Deletion of the lipid kinase PIKfyve in Kras-driven pancreatic genetically engineered mouse model
Journal Articles

Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

Lanbo Xiao, Tongchen He, Olaf Klingbeil, Young Eleanor, Xiaoli Wu, Yuanyuan Qiao, Abhijit Parolia, Sanjana Eyunni, Rahul Mannan, Somnath Mahapatra, NamHoon Kim, Heng Zheng, Fengyun Su, Xuhong Cao, Susanta Samajdar, Murali Ramachandra, Christopher R. Vakoc, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6602.
https://doi.org/10.1158/1538-7445.AM2024-6602
Published: 22 March 2024
View articletitled, Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
Journal Articles

Abstract 860: Pan-tissue master regulator inference reveals mechanisms of MHC alterations in cancers

Mahnoor N. Gondal, Rahul Mannan, Yi Bao, Jing Hu, Marcin Cieslik, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 860.
https://doi.org/10.1158/1538-7445.AM2024-860
Published: 22 March 2024
View articletitled, Abstract 860: Pan-tissue master regulator inference reveals mechanisms of MHC alterations in cancers
Journal Articles

Abstract 4504: Discovery of CBPD-409 and CBPD-268 as highly potent and orally efficacious CBP/p300 PROTAC degraders for the treatment of castration-resistant prostate cancer

Zhixiang Chen, Mi Wang, Dimin Wu, Lijie Zhao, Tianfeng Xu, Hoda Metwally, Yu Wang, Donna McEachern, Wei Jiang, Longchuan Bai, Jie Luo, Meilin Wang, Ruiting Li, John Takyi-Williams, Lu Wang, Qiuxia Li, Bo Wen, Duxin Sun, Arul M. Chinnaiyan, Shaomeng Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4504.
https://doi.org/10.1158/1538-7445.AM2024-4504
Published: 22 March 2024
View articletitled, Abstract 4504: Discovery of CBPD-409 and CBPD-268 as highly potent and orally efficacious CBP/p300 PROTAC degraders for the treatment of castration-resistant prostate cancer
Journal Articles

Abstract 3300: Dual inhibition of PIKfyve and KRAS/MAPK as a potential for therapeutic strategy for pancreatic ductal adenocarcinoma

Jasmine P. Wisniewski, Caleb Cheng, Bailey Jackson, Ahmet Korkaya, Sydney Peters, Yuanyuan Qiao, Costas A. Lyssiotis, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3300.
https://doi.org/10.1158/1538-7445.AM2024-3300
Published: 22 March 2024
View articletitled, Abstract 3300: Dual inhibition of PIKfyve and KRAS/MAPK as a potential for therapeutic strategy for pancreatic ductal adenocarcinoma
Journal Articles

Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo-enhanceosome complex in prostate cancer cells

Abhijit Parolia, Brijesh K. Verma, Sanjana Eyunni, Sweta Aras, Sandra E. Carson, Eleanor Young, Chandan K. Das, James M. George, Reyaz ur Rasool, Prathibha Gajjala, Mohammed Alhusayan, Erick Mitchell-Velasquez, Lanbo Xiao, Jie Luo, Mustapha Jaber, Xuhong Cao, Fengyun Su, Rui Wang, Lianchao Liu, Zhen Wang, Ke Ding, Arul M. Chinnaiyan, Irfan Asangani
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A055.
https://doi.org/10.1158/1538-7445.PRCA2023-A055
Published: 02 June 2023
View articletitled, Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo-enhanceosome complex in prostate cancer cells
Journal Articles

Abstract A067: Cellular cartography reveals transcriptional specificity and spatial organization of diverse luminal epithelial cells in the murine prostate

Hanbyul Cho, Yuping Zhang, Jean Tien, Jie Luo, June E. Wilke, Saravana M. Dhanasekaran, Rahul Mannan, Lisha Wang, Fengyun Su, Rui Wang, Evan T. Keller, Xuhong Cao, Sethu Pitchaya, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A067.
https://doi.org/10.1158/1538-7445.PRCA2023-A067
Published: 02 June 2023
View articletitled, Abstract A067: Cellular cartography reveals transcriptional specificity and spatial organization of diverse luminal epithelial cells in the murine prostate
Journal Articles

Abstract A027: Identification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis

Haolong Li, Noah Younger, Hyun Jin Shin, Bhavna Malik, Shuang G. Zhao, Sethuramasundaram Pitchiaya, Marsha Calvert, Meng Zhang, Laura Chang, Lisa Chesner, Junjie Hua, Kathy Li, Vishal Kothari, Emily Egusa, Jonathan Chou, Rajdeep Das, Alma Burlingame, Arul M. Chinnaiyan, Hui Li, Felix Y. Feng
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A027.
https://doi.org/10.1158/1538-7445.PRCA2023-A027
Published: 02 June 2023
View articletitled, Abstract A027: Identification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis
Journal Articles

Abstract 3523: A systematic comparison of molecular features shared by H3K27-altered diffuse midline gliomas and posterior fossa A ependymomas

Matthew Pun, Drew Pratt, Patricia R. Nano, Piyush K. Joshi, Li Jiang, Bernhard Englinger, Arvind Rao, Marcin Cieslik, Arul M. Chinnaiyan, Kenneth Aldape, Stefan Pfister, Mariella G. Filbin, Aparna Bhaduri, Sriram Venneti
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3523.
https://doi.org/10.1158/1538-7445.AM2023-3523
Published: 04 April 2023
View articletitled, Abstract 3523: A systematic comparison of molecular features shared by H3K27-altered diffuse midline gliomas and posterior fossa A ependymomas
Journal Articles

Abstract 4011: Preferential cytotoxicity of ESK981 in neuroendocrine prostate cancer

Yang Zheng, Kyle J. Garcia-Rogers, Yi Bao, Rahul Mannan, Tongchen He, Sarah N. Yee, Caleb Cheng, Xia Jiang, Isabella E. Taylor, Xuhong Cao, Yuzhuo Wang, Yuanyuan Qiao, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4011.
https://doi.org/10.1158/1538-7445.AM2023-4011
Published: 04 April 2023
View articletitled, Abstract 4011: Preferential cytotoxicity of ESK981 in neuroendocrine prostate cancer
Journal Articles

Abstract 1634: Novel autophagy inhibitor ESK981 potentiates MEK inhibition cytotoxicity in pancreatic cancer

Caleb Cheng, Jasmine Wisniewski, Bailey Jackson, Yi Bao, Yuanyuan Qiao, Costas A. Lyssiotis, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1634.
https://doi.org/10.1158/1538-7445.AM2023-1634
Published: 04 April 2023
View articletitled, Abstract 1634: Novel autophagy inhibitor ESK981 potentiates MEK inhibition cytotoxicity in pancreatic cancer
Journal Articles

Abstract 3428: Discovery of a highly potent and selective dual PROTAC degrader of CDK12 and CDK13

Yu Chang, Jianzhang Yang, Jean Ching-Yi Tien, Zhen Wang, Yang Zhou, Pujuan Zhang, Weixue Huang, Josh Vo, Ingrid J. Apel, Cynthia Wang, Victoria Zhixuan Zeng, Yunhui Cheng, Shuqin Li, George Xiaoju Wang, Ke Ding, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3428.
https://doi.org/10.1158/1538-7445.AM2023-3428
Published: 04 April 2023
View articletitled, Abstract 3428: Discovery of a highly potent and selective dual PROTAC degrader of CDK12 and CDK13
Journal Articles

Abstract 5595: Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance

Andi K. Cani, Emily M. Dolce, Kevin Hu, Chia-Jen Liu, Elizabeth P. Darga, Dan Robinson, Yi-Mi Wu, Dafydd G. Thomas, Costanza Paoletti, Scott A. Tomlins, James M. Rae, Aaron M. Udager, Arul M. Chinnaiyan, Erin F. Cobain, Daniel F. Hayes
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5595.
https://doi.org/10.1158/1538-7445.AM2023-5595
Published: 04 April 2023
View articletitled, Abstract 5595: Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance
Journal Articles

Abstract 5502: Androgen blockade confers sensitivity to PIKfyve inhibition in prostate cancer

Yuanyuan Qiao, Sarah Nicole Yee, Caleb Cheng, Yang Zheng, Jie Luo, Yi Bao, Xia Jiang, Xuhong Cao, Yuping Zhang, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5502.
https://doi.org/10.1158/1538-7445.AM2023-5502
Published: 04 April 2023
View articletitled, Abstract 5502: Androgen blockade confers sensitivity to PIKfyve inhibition in prostate cancer