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Arjun Bhutkar
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Journal Articles

Abstract C014: Broadening the repertoire of PDAC-specific targets for immune-based therapy through high-resolution immunopeptidomics

Free
Zackery A. Ely, William A. Freed-Pastor, Zachary J. Kulstad, Jennifer G. Abelin, Eva Verzani, Kevin S. Kapner, Susan Klaeger, Karl R. Clauser, Miles Agus, Alex M. Jaeger, Nimisha B. Pattada, Arjun Bhutkar, Andrew J. Aguirre, Steven A. Carr, Tyler Jacks
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C014.
https://doi.org/10.1158/1538-7445.PANCA22-C014
Published: 15 November 2022
View articletitled, Abstract C014: Broadening the repertoire of PDAC-specific targets for immune-based therapy through high-resolution immunopeptidomics
Journal Articles

Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State

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Kenneth L. Pitter, Olivera Grbovic-Huezo, Simon Joost, Anupriya Singhal, Melissa Blum, Katherine Wu, Matilda Holm, Alexander Ferrena, Arjun Bhutkar, Anna Hudson, Nicolas Lecomte, Elisa de Stanchina, Ronan Chaligne, Christine A. Iacobuzio-Donahue, Dana Pe'er, Tuomas Tammela
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3549–3560.
https://doi.org/10.1158/0008-5472.CAN-22-1742
Published: 04 October 2022
View articletitled, Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State
Open the PDF for Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State in another window
Includes: Supplementary data
Journal Articles

Abstract 2194: Rapid interrogation of colon cancer driver genes in vivo using split Cre and CRISPR-Cas9

Free
Daniel Zhang, Peter Westcott, Santiago Naranjo, Haley Hauck, William Rideout, Nate Sacks, Arjun Bhutkar, Justin Patten, Norihiro Goto, Joseph Sedlak, Tyler Jacks
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2194.
https://doi.org/10.1158/1538-7445.AM2022-2194
Published: 15 June 2022
View articletitled, Abstract 2194: Rapid interrogation of colon cancer driver genes in vivo using split Cre and CRISPR-Cas9
Journal Articles

Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis

Free
William Freed-Pastor, Laurens Lambert, Zackery Ely, Nimisha Pattada, Arjun Bhutkar, Alex Jaeger, George Eng, Kim Mercer, William Hwang, Tyler Jacks
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-063.
https://doi.org/10.1158/1538-7445.PANCA21-PO-063
Published: 15 November 2021
View articletitled, Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis
Journal Articles

Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

Free
Carla P. Concepcion, Sai Ma, Lindsay M. LaFave, Arjun Bhutkar, Manyuan Liu, Lydia P. DeAngelo, Jonathan Y. Kim, Isabella Del Priore, Adam J. Schoenfeld, Vinay K. Kartha, Peter M. Westcott, Francisco J. Sánchez-Rivera, Kevin Meli, Manav Gupta, Gregory J. Riely, Natasha Rekhtman, Charles M. Rudin, Carla F. Kim, Aviv Regev, Jason D. Buenrostro, Tyler Jacks
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2506.
https://doi.org/10.1158/1538-7445.AM2021-2506
Published: 01 July 2021
View articletitled, Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung
Journal Articles

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

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Manav Gupta, Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson, Francisco J. Sanchez-Rivera, Patrizia Pessina, Jonathan Y. Kim, Antoine Simoneau, Margherita Paschini, Mary C. Beytagh, Caroline R. Stanclift, Monica Schenone, D.R. Mani, Chendi Li, Audris Oh, Fei Li, Hai Hu, Angeliki Karatza, Roderick T. Bronson, Alice T. Shaw, Aaron N. Hata, Kwok-Kin Wong, Lee Zou, Steven A. Carr, Tyler Jacks, Carla F. Kim
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3841–3854.
https://doi.org/10.1158/0008-5472.CAN-20-1744
Published: 15 September 2020
View articletitled, BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
Open the PDF for BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency in another window
Includes: Supplementary data
Journal Articles

Abstract A35: Microenvironmental adaptations drive obesity-associated pancreatic cancer

Free
Katherine Minjee Chung, Jaffarguribal Singh, Lauren Lawres, Kimberly Judith Dorans, Rebecca Robbins, Arjun Bhutkar, Ana Babic, Sara A. Vayrynen, Andressa D. Costa, Jonathan A. Nowak, Daniel T. Chang, Richard F. Dunne, Aram F. Hezel, Albert C. Koong, Joshua J. Wilhelm, Melena D. Bellin, Vibe Nylander, Anna L. Gloyn, Mark I. McCarthy, Brian M. Wolpin, Tyler Jacks, Charles S. Fuchs, Mandar Deepak Muzumdar
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): A35.
https://doi.org/10.1158/1538-7445.PANCA19-A35
Published: 13 December 2019
View articletitled, Abstract A35: Microenvironmental adaptations drive obesity-associated pancreatic cancer
Journal Articles

Abstract LB-284: Engineering a hypermutant mouse model of NSCLC to modulate immune response

Free
Olivia C. Smith, Peter M. Westcott, David A. Canner, William M. Rideout, Arjun Bhutkar, Mary C. Beytagh, Tuomas Tammela, Tyler E. Jacks
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-284.
https://doi.org/10.1158/1538-7445.AM2018-LB-284
Published: 01 July 2018
View articletitled, Abstract LB-284: Engineering a hypermutant mouse model of NSCLC to modulate immune response
Journal Articles

Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities

Free
Rodrigo Romero, Volkan I. Sayin, Davidson M. Shawn, Matthew Bauer, Simranjit X. Singh, Sarah LeBoeuf, Triantafyllia R. Karakousi, Donald C. Ellis, Arjun Bhutkar, Francisco Sanchez-Rivera, Lakshmipriya Subbaraj, Britney Martinez, Roderick T. Bronson, Justin R. Prigge, Edward E. Schmidt, Craig J. Thomas, Angela Davies, Igor Dolgalev, Adriana Heguy, Viola Allaj, John T. Piorier, Andre L. Moreira, Charles M. Rudin, Harvey I. Pass, Matthew G. Vander Heiden, Tyler Jacks, Thales Papagiannakopoulos
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A43.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A43
Published: 14 May 2018
View articletitled, Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities
Journal Articles

Abstract A05: Investigating mechanisms of obesity-mediated pancreatic cancer progression

Free
Mandar Deepak Muzumdar, Kimberly Judith Dorans, Katherine Minjee Chung, Arjun Bhutkar, Charles Fuchs, Tyler Jacks
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A05.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A05
Published: 14 May 2018
View articletitled, Abstract A05: Investigating mechanisms of obesity-mediated pancreatic cancer progression
Journal Articles

Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells

Free
Pan-Yu Chen, Mandar Deepak Muzumdar, Kimberly Judith Dorans, Rebecca Robbins, Arjun Bhutkar, Amanda del Rosario, Philipp Mertins, Jana Qiao, Anette Claudia Schafer, Frank Gertler, Steven Carr, Tyler Jacks
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (4): 985–1002.
https://doi.org/10.1158/0008-5472.CAN-17-2129
Published: 14 February 2018
View articletitled, Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells
Open the PDF for Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract A44: The role of PHF6 in maintaining pre-B cell commitment in B-cell acute lymphoblastic leukemia

Free
Yadira M. Soto-Feliciano, Jordan ME Bartlebaugh, Yunpeng Liu, Francisco J. Sánchez-Rivera, Abraham S. Weintraub, Arjun Bhutkar, Tyler E. Jacks, Richard A. Young, Michael T. Hemann
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): A44.
https://doi.org/10.1158/1538-7445.CHROMEPI15-A44
Published: 14 January 2016
View articletitled, Abstract A44: The role of PHF6 in maintaining pre-B cell commitment in B-cell acute lymphoblastic leukemia
Journal Articles

Abstract 1084: Comprehensive genomic analysis of murine small cell lung carcinoma uncovers recurrent Pten alterations that drive tumor progression and alter tumor genome evolution.

Free
David G. McFadden, Thales Papagiannakopoulos, Kristian Cibulskis, Chip Stewart, Scott Carter, Amaro Taylor-Weiner, Arjun Bhutkar, Carrie Sougnez, Alison Dooley, Erica Shefler, Eric Lander, Stacey Gabriel, Gad Getz, Tyler Jacks
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1084.
https://doi.org/10.1158/1538-7445.AM2013-1084
Published: 15 April 2013
View articletitled, Abstract 1084: Comprehensive genomic analysis of murine small cell lung carcinoma uncovers recurrent Pten alterations that drive tumor progression and alter tumor genome evolution.
Journal Articles

Abstract 2957: Uncovering tumor-specific components of the p53 pathway using mouse models and RNAi

Free
Francisco J. Sánchez-Rivera, David M. Feldser, John Doench, Arjun Bhutkar, Corbin E. Meacham, David E. Root, Michael T. Hemann, Tyler Jacks
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2957.
https://doi.org/10.1158/1538-7445.AM2012-2957
Published: 15 April 2012
View articletitled, Abstract 2957: Uncovering tumor-specific components of the p53 pathway using mouse models and RNAi