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Journal Articles

Abstract 3731: Epigenetic control of tumor cell killing by natural killer cells

Joyce Pasion, Darko Barisic, Cem Meydan, Kong Y. Ng, Maria Tello Lafoz, Morgan Huse, Ari Melnick, Hans-Guido Wendel
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3731.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3731
Published: 15 June 2022
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Abstract LB014: Translational activation of ATF4 through mitochondrial anaplerotic metabolic pathways is required for DLBCL growth and survival

Meng Li, Matthew R. Teater, Jun Young Hong, Cihangir Duy, Hao Shen, Ling Wang, Zhengming Chen, Leandro Cerchietti, Hening Lin, Ari Melnick
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB014.
DOI: https://doi.org/10.1158/1538-7445.AM2021-LB014
Published: 01 July 2021
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Abstract 651: Chemotherapy induces a transient senescence-like state capable of initiating AML recurrence

Meng Li, Matt Teater, Cem Meydan, Francine E. Garrett-Bakelman, Christopher Chin, Martin Carroll, Ari Melnick, Cihangir Duy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 651.
DOI: https://doi.org/10.1158/1538-7445.AM2020-651
Published: 15 August 2020
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Journal Articles

Abstract 2983: CD25 enables oncogenic BCR- and TCR-signaling and represents a therapeutic target in lymphoblastic malignancies

Jaewoong Lee, Huimin Geng, Zhengshan Chen, Gang Xiao, Kadriye Nehir Cosgun, Francesca Zammarchi, Patrick Van Berkel, Ari Melnick, Elisabeth Paietta, Markus Muschen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2983.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2983
Published: 01 July 2018
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Journal Articles

Abstract 797: Targeting HDAC3 reactivates immunosurveillance and enhances immunocheckpoint activity in B-cell lymphoma

Patrizia Mondello, Matt Teater, Lorena Fontan, Matthew Durant, Elisa de Stanchina, Giorgio Inghirami, Michael Green, Ari Melnick
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 797.
DOI: https://doi.org/10.1158/1538-7445.AM2018-797
Published: 01 July 2018
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Journal Articles

MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia

Nakhle S. Saba, Deanna H. Wong, Georges Tanios, Jessica R. Iyer, Patricia Lobelle-Rich, Eman L. Dadashian, Delong Liu, Lorena Fontan, Erik K. Flemington, Cydney M. Nichols, Chingiz Underbayev, Hana Safah, Ari Melnick, Adrian Wiestner, Sarah E. M. Herman
Journal: Cancer Research
Cancer Res (2017) 77 (24): 7038–7048.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-2485
Published: 14 December 2017
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Includes: Supplementary data
Journal Articles

Abstract 3863: A subset of poorly prognostic pediatric posterior fossa ependymomas exhibit lowered H3K27me3 and DNA hypomethylation and show epigenetic similarities with H3K27M mutant diffuse intrinsic pontine gliomas

Sriram Venneti, Jill Bayliss, Piali Mukherjee, Chao Lu, Siddhant Jain, Chan Chung, Daniel Martinez, Benjamin Sabari, Ashley Margol, Pooja Panwalkar, Abhijit Paroloia, Melike Pekmezci, Richard Mc Eachin, Marcin Cieslik, Benita Tamrazi, Benjamin Garcia, Gaspare La Rocca, Mariarita Santi, Peter Lewis, Cynthia Hawkins, Ari Melnick, C David Allis, Craig B. Thompson, Arul Chinnaiyan, Alexander R. Judkins
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3863.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3863
Published: 01 July 2017
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Journal Articles

Abstract LB-303: Substrate-mimetic covalent inhibitor of MALT1 is most effective against CARD11 mutant ABC-DLBCL

Lorena Fontan, David Scott, John Hatcher, Qi Qiao, Ilkay Us, Gabriella Casalena, Mariette Bekkers, Ulrike Philippar, Matthew Durant, Spandan Chennamadhavuni, Hao Wu, Nathaniel Gray, Ari Melnick
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-303.
DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-303
Published: 01 July 2017
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Journal Articles

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model

Wei Du, Rebecca Goldstein, Yanwen Jiang, Omar Aly, Leandro Cerchietti, Ari Melnick, Olivier Elemento
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (8): 1818–1830.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0476
Published: 13 April 2017
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Includes: Supplementary data
Journal Articles

Abstract 1271: The transcription factor BCL6 is a rational target in non-small cell lung cancer (NSCLC)

Rossella Marullo, Haelee Ahn, Mariano Cardenas, Ari Melnick, Fengtian Xue, Leandro Cerchietti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1271.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1271
Published: 15 July 2016
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Journal Articles

Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells

Anna A. Rodina, Tony Taldone, Yanlong Kang, Pallav Patel, John Koren, Pengrong Yan, Erica DaGama Gomes, Chenghua Yang, Maulik Patel, Liza Shrestha, Stefan Ochiana, Ronnie Maharaj, Alexander Gozman, Marc Cox, Hediye Erdjument-Bromage, Ronald Hendrickson, Leandro Cerchietti, Ari Melnick, Monica Guzman, Gabriela Chiosis
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1733.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1733
Published: 01 August 2015
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Journal Articles

Abstract 2693: Harnessing MALT1 inhibition for rational combinatorial therapy of ABC-DLBCL

Lorena Fontan, Chenghua Yang, Venkataraman Kabaleeswaran, Laurent Volpon, Michael Osborne, Elena Beltran, Monica Rosen, Rita Shaknovich, Shao N. Yang, Randy D. Gascoyne, Leandro Cerchietti, Jose A. Martinez-Climent, J. Fraser Glickman, Katherine Borden, Hao Wu, Ari Melnick
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2693.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2693
Published: 01 October 2014
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Journal Articles

Abstract 4232: Small molecule phenotypic targeting of aggressive B-cell lymphomas

Mariano G. Cardenas, Matt R. Teater, Nieves Calvo-Vidal, Shao Ning Yang, J F. Glickman, Ari Melnick, Leandro Cerchietti
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4232.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4232
Published: 01 October 2014
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Journal Articles

Abstract IA20: Epigenetic deregulation of gene expression

Ari Melnick
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): IA20.
DOI: https://doi.org/10.1158/1538-7445.CEC13-IA20
Published: 13 May 2014
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Journal Articles

Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Warren Fiskus, Nakhle Saba, Min Shen, Mondana Ghias, Jinyun Liu, Soumyasri Das Gupta, Lata Chauhan, Rekha Rao, Sumedha Gunewardena, Kevin Schorno, Christopher P. Austin, Kami Maddocks, John Byrd, Ari Melnick, Peng Huang, Adrian Wiestner, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2014) 74 (9): 2520–2532.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2033
Published: 30 April 2014
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Includes: Supplementary data
Journal Articles

Abstract A31: ERG-mediated alterations in chromatin conformation

David S. Rickman, Ari Melnick, Olivier Elemento, Mark Rubin, T. David Soong, Benjamin Moss, Juan Miguel Mosquera, Jan Dlabal, Stephane Terry, Theresa MacDonald, Karen Bunting, Francesca Demichelis
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): A31.
DOI: https://doi.org/10.1158/1538-7445.PRCA2012-A31
Published: 09 May 2013
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Journal Articles

Abstract LB-111: A stable transcription factor complex nucleated by dimeric AML1-ETO controls leukemogenesis.

Xiao-Jian Sun, Zhanxin Wang, Lan Wang, Yanwen Jiang, T. David Soong, Nils Kost, Wei-Yi Chen, Olivier Elemento, Wolfgang Fischle, Ari Melnick, Dinshaw J. Patel, Stephen D. Nimer, Robert G. Roeder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-111.
DOI: https://doi.org/10.1158/1538-7445.AM2013-LB-111
Published: 15 April 2013
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Journal Articles

Abstract 2334: Targeting inhibitory phosphatase signaling in Ph+ ALL.

Seyedmehdi Shojaee, Maike Buchner, Sigal Gery, Huimin Geng, Lai N. Chan, Ari Melnick, Phillip H. Koeffler, Markus Müschen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2334.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2334
Published: 15 April 2013
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Journal Articles

Abstract 3183: Deep-sequencing reveals distinct clonal evolution patterns of DLBCL relapse and identifies mutant MLL2 as potential early driver.

Yanwen Jiang, David Redmond, Kui Nie, Peter Martin, Ari Melnick, Wayne Tam, Olivier Elemento
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3183.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3183
Published: 15 April 2013
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Abstract 2045: Oncoproteomic analysis of diffuse large B cell lymphomas reveals rationale for combination treatments.

Rebecca L. Goldstein, Leandro C. Cerchietti, Gabriela Chiosis, Ari Melnick
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2045.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2045
Published: 15 April 2013
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