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Arabella Young
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Journal Articles

Abstract 1031: Liver metastasis mediated control of distant tumor-specific immunity and response to checkpoint immunotherapy

James C. Lee, Sadaf Mehdizadeh, Arabella Young, Jennifer Bridge, Ilgiz A. Mufazalov, Adil Daud, Jeffrey A. Bluestone
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1031.
https://doi.org/10.1158/1538-7445.AM2020-1031
Published: 15 August 2020
View articletitled, Abstract 1031: Liver metastasis mediated control of distant tumor-specific immunity and response to checkpoint immunotherapy
Journal Articles

A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment

Arabella Young, Shin Foong Ngiow, Yulong Gao, Ann-Marie Patch, Deborah S. Barkauskas, Meriem Messaoudene, Gene Lin, Jerome D. Coudert, Kimberley A. Stannard, Laurence Zitvogel, Mariapia A. Degli-Esposti, Eric Vivier, Nicola Waddell, Joel Linden, Nicholas D. Huntington, Fernando Souza-Fonseca-Guimaraes, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2018) 78 (4): 1003–1016.
https://doi.org/10.1158/0008-5472.CAN-17-2826
Published: 14 February 2018
View articletitled, A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy

Julia Reinhardt, Jennifer Landsberg, Jonathan L. Schmid-Burgk, Bartomeu Bibiloni Ramis, Tobias Bald, Nicole Glodde, Dorys Lopez-Ramos, Arabella Young, Shin Foong Ngiow, Daniel Nettersheim, Hubert Schorle, Thomas Quast, Waldemar Kolanus, Dirk Schadendorf, Georgina V. Long, Jason Madore, Richard A. Scolyer, Antoni Ribas, Mark J. Smyth, Paul C. Tumeh, Thomas Tüting, Michael Hölzel
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4697–4709.
https://doi.org/10.1158/0008-5472.CAN-17-0395
Published: 31 August 2017
View articletitled, MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
Open the PDF for MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis

Arabella Young, Shin Foong Ngiow, Jason Madore, Julia Reinhardt, Jennifer Landsberg, Arash Chitsazan, Jai Rautela, Tobias Bald, Deborah S. Barkauskas, Elizabeth Ahern, Nicholas D. Huntington, Dirk Schadendorf, Georgina V. Long, Glen M. Boyle, Michael Hölzel, Richard A. Scolyer, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4684–4696.
https://doi.org/10.1158/0008-5472.CAN-17-0393
Published: 31 August 2017
View articletitled, Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis
Open the PDF for Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor

Shin Foong Ngiow, Arabella Young, Stephen J. Blake, Geoffrey R. Hill, Hideo Yagita, Michele W. L. Teng, Alan J. Korman, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6266–6277.
https://doi.org/10.1158/0008-5472.CAN-16-2141
Published: 31 October 2016
View articletitled, Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor
Open the PDF for Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell–Rich Tumor in another window
Includes: Supplementary data
Journal Articles

Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis

Deepak Mittal, Debottam Sinha, Deborah Barkauskas, Arabella Young, Murugan Kalimutho, Kimberley Stannard, Franco Caramia, Benjamin Haibe-Kains, John Stagg, Kum Kum Khanna, Sherene Loi, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4372–4382.
https://doi.org/10.1158/0008-5472.CAN-16-0544
Published: 31 July 2016
View articletitled, Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis
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Includes: Supplementary data
Journal Articles

A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1

Shin Foong Ngiow, Arabella Young, Nicolas Jacquelot, Takahiro Yamazaki, David Enot, Laurence Zitvogel, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2015) 75 (18): 3800–3811.
https://doi.org/10.1158/0008-5472.CAN-15-1082
Published: 14 September 2015
View articletitled, A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1
Open the PDF for A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1 in another window
Includes: Supplementary data
Journal Articles

Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor

Deepak Mittal, Arabella Young, Kimberley Stannard, Michelle Yong, Michele W.L. Teng, Bertrand Allard, John Stagg, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2014) 74 (14): 3652–3658.
https://doi.org/10.1158/0008-5472.CAN-14-0957
Published: 14 July 2014
View articletitled, Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor
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