1-20 of 47
Antonio Jimeno
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT180: Safety and efficacy of vibostolimab (vibo) plus pembrolizumab (pembro) and coformulation of vibo/pembro in ovarian cancer naive to PD-1/PD-L1 inhibitors

Ruth Perets, Martin Gutierrez, Sun Young Rha, Sarah Taylor, Brian Stein, Antonio Jimeno, Ira Winer, Diana Chen, Tanya Keenan, Mohini Rajasagi, Mallika Lala, Jane Healy, Ronnie Shapira-Frommer
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT180.
https://doi.org/10.1158/1538-7445.AM2022-CT180
Published: 15 June 2022
View article titled, Abstract CT180: Safety and efficacy of vibostolimab (vibo) plus pembrolizumab (pembro) and coformulation of vibo/pembro in ovarian cancer naive to PD-1/PD-L1 inhibitors
Journal Articles

Abstract CT235: A Phase 2, multicenter study of autologous tumor infiltrating lymphocytes (TIL, LN 144/LN-145/LN-145-S1) in patients with solid tumors

Scott Gettinger, Harriet Kluger, Adam Schoenfeld, Allison Betof-Warner, Kai He, Ammar Sukari, Bernard Doger de Speville Uribe, Sylvia Lee, Simon Haefliger, Zelanna Goldberg, Alex Cacovean, Rana Fiaz, Guang Chen, Madan Jagasia, Friedrich Graf Finckenstein, Maria Fardis, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT235.
https://doi.org/10.1158/1538-7445.AM2021-CT235
Published: 01 July 2021
View article titled, Abstract CT235: A Phase 2, multicenter study of autologous tumor infiltrating lymphocytes (TIL, LN 144/LN-145/LN-145-S1) in patients with solid tumors
Journal Articles

Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells

Karina E. Gomez, FangLong Wu, Stephen B. Keysar, J. Jason Morton, Bettina Miller, Tugs-Saikhan Chimed, Phuong N. Le, Cera Nieto, Farshad N. Chowdhury, Anit Tyagi, Traci R. Lyons, Christian D. Young, Hongmei Zhou, Hilary L. Somerset, Xiao-Jing Wang, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4185–4198.
https://doi.org/10.1158/0008-5472.CAN-20-1079
Published: 02 October 2020
View article titled, Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells
Open the PDF for Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells in another window
Includes: Supplementary data
Journal Articles

Abstract CT032: A phase 1/2, open-label, multicenter, dose escalation and efficacy study of mRNA-2416, a lipid nanoparticle encapsulated mRNA encoding human OX40L, for intratumoral injection alone or in combination with durvalumab for patients with advanced malignancies

Antonio Jimeno, Shilpa Gupta, Ryan Sullivan, Khanh T. Do, Wallace L. Akerley, Ding Wang, Deanna Teoh, Kurt Schalper, Sima J. Zacharek, Jing Sun, Andressa S. Laino, Joshua Frederick, Honghong Zhou, William Randolph, Stephanie Pascarella, Lisa Johansen, Pamela S. Cohen, ROBERT S. MEEHAN, Todd M. Bauer
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT032.
https://doi.org/10.1158/1538-7445.AM2020-CT032
Published: 15 August 2020
View article titled, Abstract CT032: A phase 1/2, open-label, multicenter, dose escalation and efficacy study of mRNA-2416, a lipid nanoparticle encapsulated mRNA encoding human OX40L, for intratumoral injection alone or in combination with durvalumab for patients with advanced malignancies
Journal Articles

Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma

Stephen B. Keysar, Nathan Gomes, Bettina Miller, Brian C. Jackson, Phuong N. Le, J. Jason Morton, Julie Reisinger, Tugs-Saikhan Chimed, Karina E. Gomez, Cera Nieto, Barbara Frederick, Gijsbertus J. Pronk, Hilary L. Somerset, Aik-Choon Tan, Xiao-Jing Wang, David Raben, Tin Tin Su, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2020) 80 (5): 1183–1198.
https://doi.org/10.1158/0008-5472.CAN-19-3232
Published: 02 March 2020
View article titled, Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma
Open the PDF for Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract CT210: A Phase I, open-label, multicenter, dose escalation study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for intratumoral injection alone and in combination with immune checkpoint blockade

Todd Bauer, Manish Patel, Antonio Jimeno, Ding Wang, Jessica McDermott, Sima Zacharek, William Randolph, Lisa Johansen, Kristen Hopson, Joshua Frederick, Tal Zaks, Robert S. Meehan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT210.
https://doi.org/10.1158/1538-7445.AM2019-CT210
Published: 01 July 2019
View article titled, Abstract CT210: A Phase I, open-label, multicenter, dose escalation study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for intratumoral injection alone and in combination with immune checkpoint blockade
Journal Articles

Abstract 5035: Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers

Shilpa Bhatia, Ayman Oweida, Shelby Lennon, Laurel Darragh, Sanjana Bukkapatnam, Benjamin Van Court, David Raben, Natalie Serkova, Antonio Jimeno, Eric Clambey, Elena Pasquale, Sana Karam
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5035.
https://doi.org/10.1158/1538-7445.AM2019-5035
Published: 01 July 2019
View article titled, Abstract 5035: Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers
Journal Articles

Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers

Shilpa Bhatia, Ayman Oweida, Shelby Lennon, Laurel B. Darragh, Dallin Milner, Andy V. Phan, Adam C. Mueller, Benjamin Van Court, David Raben, Natalie J. Serkova, Xiao-Jing Wang, Antonio Jimeno, Eric T. Clambey, Elena B. Pasquale, Sana D. Karam
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2722–2735.
https://doi.org/10.1158/0008-5472.CAN-18-3257
Published: 15 May 2019
View article titled, Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers
Open the PDF for Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract CT158: Phase II study of monalizumab, a first-in-class NKG2A monoclonal antibody, in combination with cetuximab in previously treated recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN): Preliminary assessment of safety and efficacy

Roger Cohen, Jérôme Fayette, Marshall Posner, Gautier Lefebvre, Jessica Bauman, Sébastien Salas, Caroline Even, Tanguy Seiwert, Dimitrios Colevas, Antonio Jimeno, Esma Saada, Barbara Burtness, Pascale André, Carine Paturel, Cécile Bonnafous, Anne-Marie Soulié, Anne Tirouvanziam-Martin, Robert Zerbib, Agnès Boyer-Chammard
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT158.
https://doi.org/10.1158/1538-7445.AM2018-CT158
Published: 01 July 2018
View article titled, Abstract CT158: Phase II study of monalizumab, a first-in-class NKG2A monoclonal antibody, in combination with cetuximab in previously treated recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN): Preliminary assessment of safety and efficacy
Journal Articles

Abstract 4169: Inhibition of EphB4-ephrin-B2 signaling results in enhanced sensitivity to cetuximab-radiation therapy in head and neck cancers

Shilpa Bhatia, Jaspreet Sharma, Sanjana Bukkapatnam, Ayman Oweida, Shelby Lennon, Parkash Gill, Antonio Jimeno, David Raben, Lynn Heasley, Sana D. Karam
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4169.
https://doi.org/10.1158/1538-7445.AM2018-4169
Published: 01 July 2018
View article titled, Abstract 4169: Inhibition of EphB4-ephrin-B2 signaling results in enhanced sensitivity to cetuximab-radiation therapy in head and neck cancers
Journal Articles

EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases

Aria Vaishnavi, Laura Schubert, Uwe Rix, Lindsay A. Marek, Anh T. Le, Stephen B. Keysar, Magdalena J. Glogowska, Matthew A. Smith, Severine Kako, Natalia J. Sumi, Kurtis D. Davies, Kathryn E. Ware, Marileila Varella-Garcia, Eric B. Haura, Antonio Jimeno, Lynn E. Heasley, Dara L. Aisner, Robert C. Doebele
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3551–3563.
https://doi.org/10.1158/0008-5472.CAN-17-0109
Published: 02 July 2017
View article titled, EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases
Open the PDF for EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases in another window
Includes: Supplementary data
Journal Articles

Abstract 5666: Safety of the first-in-class anti-NKG2A monoclonal antibody monalizumab in combination with cetuximab: a phase Ib/II study in recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN)

Roger B. Cohen, Sébastien Salas, Caroline Even, Nuria Kotecki, Antonio Jimeno, Anne-Marie Soulié, Anne Tirouvanziam-Martin, Robert Zerbib, Pascale André, Agnès Boyer-Chammard, Jérôme Fayette
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5666.
https://doi.org/10.1158/1538-7445.AM2017-5666
Published: 01 July 2017
View article titled, Abstract 5666: Safety of the first-in-class anti-NKG2A monoclonal antibody monalizumab in combination with cetuximab: a phase Ib/II study in recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN)
Journal Articles

Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap

J. Jason Morton, Gregory Bird, Yosef Refaeli, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6153–6158.
https://doi.org/10.1158/0008-5472.CAN-16-1260
Published: 31 October 2016
View article titled, Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap
Open the PDF for Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap in another window
Journal Articles

Abstract LB-127: Role of EphB4 in radiosensitization of head and neck squamous cell carcinoma

Shilpa Bhatia, Kellen Hirsch, Jaspreet Sharma, Stephen Keysar, Antonio Jimeno, Parkash Gill, Xiao-Jing Wang, Sana D. Karam
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-127.
https://doi.org/10.1158/1538-7445.AM2016-LB-127
Published: 15 July 2016
View article titled, Abstract LB-127: Role of EphB4 in radiosensitization of head and neck squamous cell carcinoma
Journal Articles

Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers

Gregory N. Gan, Justin Eagles, Stephen B. Keysar, Guoliang Wang, Magdalena J. Glogowska, Cem Altunbas, Ryan T. Anderson, Phuong N. Le, J. Jason Morton, Barbara Frederick, David Raben, Xiao-Jing Wang, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7024–7036.
https://doi.org/10.1158/0008-5472.CAN-14-1346
Published: 30 November 2014
View article titled, Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
Open the PDF for Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 5255: EGFR is a conspiring kinase in gene fusion positive lung cancer

Aria Vaishnavi, Anh T. Le, Stephen B. Keysar, Christine M. Lovly, Severine Kako, Marileila Varella-Garcia, Antonio Jimeno, Robert C. Doebele
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5255.
https://doi.org/10.1158/1538-7445.AM2014-5255
Published: 01 October 2014
View article titled, Abstract 5255: EGFR is a conspiring kinase in gene fusion positive lung cancer
Journal Articles

Hedgehog Signaling Alters Reliance on EGF Receptor Signaling and Mediates Anti-EGFR Therapeutic Resistance in Head and Neck Cancer

Stephen B. Keysar, Phuong N. Le, Ryan T. Anderson, J. Jason Morton, Daniel W. Bowles, Jeramiah J. Paylor, Brian W. Vogler, Jackie Thorburn, Pamela Fernandez, Magdalena J. Glogowska, Sarah M. Takimoto, Daniel B. Sehrt, Gregory N. Gan, Justin R. Eagles-Soukup, Hilary Serracino, Fred R. Hirsch, M. Scott Lucia, Andrew Thorburn, John I. Song, Xiao-Jing Wang, Antonio Jimeno
Journal: Cancer Research
Cancer Res (2013) 73 (11): 3381–3392.
https://doi.org/10.1158/0008-5472.CAN-12-4047
Published: 30 May 2013
View article titled, Hedgehog Signaling Alters Reliance on EGF Receptor Signaling and Mediates Anti-EGFR Therapeutic Resistance in Head and Neck Cancer
Open the PDF for Hedgehog Signaling Alters Reliance on EGF Receptor Signaling and Mediates Anti-EGFR Therapeutic Resistance in Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3363: Pharmacodynamic (PD) assessment of drug activity in tumor tissue from patients (pts) enrolled in a Phase I study of MEHD7945A (MEHD), a first-in-class HER3/EGFR dual action antibody, in pts with locally advanced or metastatic epithelial tumors.

Dejan Juric, Rodrigo Dienstmann, Andres Cervantes, Manuel Hidalgo, Wells Messersmith, George Blumenschein, Jose Baselga, Josep Tabernero, Desamparados Roda, Antonio Calles, Antonio Jimeno, Lukas Amler, Howard Stern, Sandra Sanabria, Elicia Penuel, Andrea Pirzkall
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3363.
https://doi.org/10.1158/1538-7445.AM2013-3363
Published: 15 April 2013
View article titled, Abstract 3363: Pharmacodynamic (PD) assessment of drug activity in tumor tissue from patients (pts) enrolled in a Phase I study of MEHD7945A (MEHD), a first-in-class HER3/EGFR dual action antibody, in pts with locally advanced or metastatic epithelial tumors.
Journal Articles

Abstract LB-198: Phase I and molecular correlates study of oral rigosertib in patients with refractory metastatic head and neck cancer and advanced solid tumors.

Antonio Jimeno, Daniel Bowles, Dara Aisner, Jennifer Diamond, Elaine Lam, Colin Weekes, Stephen Leong, Lia Gore, Elizabeth Freas, Gail Eckhardt, Wells Messersmith, Marileila Garcia-Varella, Francois Wilhelm
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-198.
https://doi.org/10.1158/1538-7445.AM2013-LB-198
Published: 15 April 2013
View article titled, Abstract LB-198: Phase I and molecular correlates study of oral rigosertib in patients with refractory metastatic head and neck cancer and advanced solid tumors.
Journal Articles

Abstract 3263: Evaluation of the activity of rigosertib, an inhibitor of PI3K and MAPK pathways, in a preclinical model of colorectal cancer.

Alicia Purkey, Eun-Kee Song, Kevin Quackenbush, Stacey Bagby, John J. Arcaroli, Antonio Jimeno, Wells Messersmith
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3263.
https://doi.org/10.1158/1538-7445.AM2013-3263
Published: 15 April 2013
View article titled, Abstract 3263: Evaluation of the activity of rigosertib, an inhibitor of PI3K and MAPK pathways, in a preclinical model of colorectal cancer.