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Anton Simeonov
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Journal Articles

Abstract B008: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping

Free
Zheqi Li, Guillermo Peluffo, Laura Stevens, Xintao Qiu, Marco Seehawer, Xiao-Yun Huang, Shawn Egri, Malvina Papanastasiou, Natalie Kingston, Clive D'Santos, Eva Papachristou, Jun Nishida, Kyle Evans, Ji-Heui Seo, Kendell Clement, Daniel Temko, Muhammad Ekram, Matthew Rees, Melissa Ronan, Jennifer Roth, Anton Simeonov, Stephen Kales, Ganesha Rai, Madhu Lal-Nag, David Maloney, Ajit Jadhav, Franziska Michor, Alex Meissner, Justin Balko, Jason Carroll, Matthew Freedman, Henry Long, Jacob Jaffe, Kornelia Polyak
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_1): B008.
https://doi.org/10.1158/1538-7445.ADVBC23-B008
Published: 01 February 2024
View articletitled, Abstract B008: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping
Journal Articles

Abstract A018: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping

Free
Zheqi Li, Guillermo Peluffo, Laura E. Stevens, Xintao Qiu, Shawn B. Egri, Malvina Papanastasiou, Natalie Kingston, Clive S. D'Santos, Eva Papachristou, Kyle Evans, Ji-Heui Seo, Kendell Clement, Daniel Temko, Muhammad Ekram, Anton Simeonov, Stephen C. Kales, Ganesha Rai, Madhu Lal-Nag, David J. Maloney, Ajit Jadhav, Franziska Michor, Alex Meissner, Jason S. Carroll, Matthew L. Freedman, Henry W. Long, Jacob D. Jaffe, Kornelia Polyak
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): A018.
https://doi.org/10.1158/1538-7445.CancEpi22-A018
Published: 01 December 2022
View articletitled, Abstract A018: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping
Journal Articles

Abstract 5957: Roles for the cancer stem cell marker Aldh1A1 in Merlin null nervous system tumors

Free
Lily Hillson, Liyam Laraba, Aditya G. Shivane, Philip Edwards, Ganesha Bantukallu, Anton Simeonov, Natalia J. Martinez, Shyh-Ming Yang, David B. Parkinson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5957.
https://doi.org/10.1158/1538-7445.AM2020-5957
Published: 15 August 2020
View articletitled, Abstract 5957: Roles for the cancer stem cell marker Aldh1A1 in Merlin null nervous system tumors
Journal Articles

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer

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Koen D. Flach, Manikandan Periyasamy, Ajit Jadhav, Dorjbal Dorjsuren, Joseph C. Siefert, Theresa E. Hickey, Mark Opdam, Hetal Patel, Sander Canisius, David M. Wilson, III, Maria Donaldson Collier, Stefan Prekovic, Marja Nieuwland, Roelof J.C. Kluin, Alexey V. Zakharov, Jelle Wesseling, Lodewyk F.A. Wessels, Sabine C. Linn, Wayne D. Tilley, Anton Simeonov, Simak Ali, Wilbert Zwart
Journal: Cancer Research
Cancer Res (2020) 80 (10): 1914–1926.
https://doi.org/10.1158/0008-5472.CAN-19-2207
Published: 15 May 2020
View articletitled, Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer
Open the PDF for Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1940: Thymine DNA glycosylase (TDG) as a novel target for melanoma

Free
Rossella Tricarico, Pietro Mancuso, Vikram Bhattacharjee, Laura Cosentino, Emmanuelle Nicolas, Margret Einarson, Neil Beeharry, Karthik Devarajan, Rich Katz, Dorjbal G. Dorjsuren, Anton Simeonov, Yuwaraj Kadariya, Guillaume Davidson, Joseph R. Testa, Irwin Davidson, Lionel Larue, Robert W. Sobol, Timothy Yen, Alfonso Bellacosa
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1940.
https://doi.org/10.1158/1538-7445.AM2018-1940
Published: 01 July 2018
View articletitled, Abstract 1940: Thymine DNA glycosylase (TDG) as a novel target for melanoma
Journal Articles

Abstract 3088: Transcription factor as target: Novel small molecule inhibits FOXM1 DNA binding and oncogenic gene products

Free
Michael Gormally, Giovanni Marsico, Ganesha Rai, Christopher Lowe, Craig Thomas, David Maloney, Sam Michael, Dijana Matak-Vincovic, Ajit Jadhav, Anton Simeonov, Shankar Balasubramanian
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3088.
https://doi.org/10.1158/1538-7445.AM2016-3088
Published: 15 July 2016
View articletitled, Abstract 3088: Transcription factor as target: Novel small molecule inhibits FOXM1 DNA binding and oncogenic gene products
Journal Articles

Abstract 4714: Targeting p53 mutant cancers through inhibition of the phosphatidylinositol-5-phosphate 4-kinases

Free
Brooke M. Emerling, Zhiwei Yang, Ryan Loughran, T.Jonathan Yang, Jared Johnson, Rajan Pragani, Mindy Davis, Min Shen, Matthew Boxer, Anton Simeonov, Lewis C. Cantley
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4714.
https://doi.org/10.1158/1538-7445.AM2015-4714
Published: 01 August 2015
View articletitled, Abstract 4714: Targeting p53 mutant cancers through inhibition of the phosphatidylinositol-5-phosphate 4-kinases
Journal Articles

Abstract LB-11: Discovery, synthesis, and structure-activity relationship of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against non-small cell lung cancer

Free
Thomas S. Dexheimer, Andrew S. Rosenthal, Diane Luci, Qin Liang, Mark A. Villamil, Ajit Jadhav, Anton Simeonov, Zhihao Zhuang, David J. Maloney
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-11.
https://doi.org/10.1158/1538-7445.AM2014-LB-11
Published: 01 October 2014
View articletitled, Abstract LB-11: Discovery, synthesis, and structure-activity relationship of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against non-small cell lung cancer
Journal Articles

Abstract 4543: High-throughput combination screening identifies novel drug-drug pairings for a Bruton's tyrosine kinase inhibitor against the ABC subtype of diffuse large B-cell lymphomas.

Free
Lesley A. Mathews, Rajarshi Guha, Paul Shinn, Ryan M. Young, Kian-Huat Lim, Jonathan Keller, Dongbo Liu, Adam Yasgar, Crystal McKnight, Matthew B. Boxer, Damien Y. Duveau, Jian-kang Jiang, Sam Michael, Bryan T. Mott, Paresma R. Patel, William Leister, David J. Maloney, Christopher A. LeClair, Ganesha Rai, Ajit Jadhav, Brian D. Peyser, Christopher P. Austin, Scott Martin, Anton Simeonov, Marc Ferrer, Louis Staudt, Craig J. Thomas
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4543.
https://doi.org/10.1158/1538-7445.AM2013-4543
Published: 15 April 2013
View articletitled, Abstract 4543: High-throughput combination screening identifies novel drug-drug pairings for a Bruton's tyrosine kinase inhibitor against the ABC subtype of diffuse large B-cell lymphomas.
Journal Articles

Abstract 3337: Modulating the APE1/NPM1 interaction in cancer.

Free
Mattia Poletto, Dorjbal Dorjsuren, Lisa Lirussi, Carlo Vascotto, Pasqualina L. Scognamiglio, Daniela Marasco, Ajit Jadhav, David J. Maloney, Anton Simeonov, David M. Wilson, Gianluca Tell
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3337.
https://doi.org/10.1158/1538-7445.AM2013-3337
Published: 15 April 2013
View articletitled, Abstract 3337: Modulating the APE1/NPM1 interaction in cancer.
Journal Articles

Identification of inhibitors of the hypoxia-inducible factor-1 signaling pathway in a cellular model.

Free
Menghang Xia, Kun Bi, Ronald Johnson, Ajit Jadhav, Pingjun Zhu, Janak Padia, Anton Simeonov, Wei Zheng, John Printen, Chris Austin, James Inglese
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1192.
Published: 15 April 2006
View articletitled, Identification of inhibitors of the hypoxia-inducible factor-1 signaling pathway in a cellular model.