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Annette T. Byrne
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Journal Articles

Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts

Jessica Giordano, Xing Yi Woo, Anuj Srivastava, Zi-Ming Zhao, Michael W. Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Francesco Galimi, Andrea Bertotti, Adam Lafferty, Alice C. O'Farrell, Elodie Modave, Diether Lambrechts, Petra ter Brugge, Violeta Serra, Elisabetta Marangoni, Rania El Botty, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A. Dean, Brandi Davis-Dusenbery, Yvonne A. Evrard, James H. Doroshow, Alana L. Welm, Bryan E. Welm, Michael T. Lewis, Bingliang Fang, Jack Roth, Funda Meric-Bernstam, Meenhard Herlyn, Michael Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Jeffrey A. Moscow, Carol J. Bult, Claudio Isella, Livio Trusolino, Annette T. Byrne, Jos Jonkers, Jeffrey H. Chuang, Enzo Medico, EurOPDX consortium & PDXNET consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1118.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1118
Published: 15 August 2020
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Journal Articles

Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts

Emilie Vinolo, Joaquin Arribas, Andrea Bertotti, Alejandra Bruna, Annette T. Byrne, Robert B. Clarke, Nathalie Conte, Steven de Jong, Didier Decaudin, Zdenka Dudova, Jos Jonkers, Daniela Krasser, Ales Krenek, Luisa Lanfrancone, Eleonora Leucci, Elisabetta Marangoni, Gunhild Mari Maelandsmo, Michaela Th. Mayrhofer, Terrence F. Meehan, Jens Henrik Norum, Hector G. Palmer, Alejandro Piris Gimenez, Leo Price, Sergio Roman-Roman, Francesca Sarno, Violeta Serra, Laura Soucek, Livio Trusolino, Marieke van de Ven, Luca Vezzadini, Alberto Villanueva, Andrea Wutte, Enzo Medico, on behalf of the EurOPDX Research Infrastructure
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1685.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1685
Published: 15 August 2020
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Journal Articles

Abstract 2012: Interrogating the in vivo anti-metastatic action of tinzaparin and simvastatin in an orthotopic surgical resection mouse model of triple negative breast cancer

Ian S. Miller, Liam P. Shiels, Grace Buckley, Kate Connor, Annette T. Byrne, Fionnuala Ní Ainle
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2012.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2012
Published: 01 July 2019
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Journal Articles

Abstract 5033: The role of the epigenetic regulator SATB2 in colon cancer progression

Donal J. Brennan, Kirsha Naicker, Sudipto Das, Bruce Moran, Rut Klinger, Fredrik Ponten, Stephen Hewitt, Karin Jirström, Annette T. Byrne, Jacintha O'Sullivan, William M. Gallagher, Darran P. O'Connor
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5033.
DOI: https://doi.org/10.1158/1538-7445.AM2019-5033
Published: 01 July 2019
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Journal Articles

Abstract 985: The EurOPDX EDIReX project: Towards a European research infrastructure on patient-derived cancer models

Enzo Medico, Mohamed Bentires-Alj, Andrew V. Biankin, Alejandra Bruna, Annette T. Byrne, Carlos Caldas, Robert B. Clarke, Georges Coukos, Olivier Elemento, Manuel Hidalgo, Giorgio Inghirami, Steven de Jong, Jos Jonkers, Ales Krenek, Eleonora Leucci, Gunhild Mari Maelandsmo, Michaela Th. Mayrhofer, Terrence F. Meehan, Simone P. Niclou, Pier Giuseppe Pelicci, Alejandro Piris-Gimenez, Leo Price, Sergio Roman-Roman, Livio Trusolino, Luca Vezzadini, Alberto Villanueva, Emilie Vinolo, on behalf of the EurOPDX Consortium
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 985.
DOI: https://doi.org/10.1158/1538-7445.AM2018-985
Published: 01 July 2018
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Journal Articles

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Terrence F. Meehan, Nathalie Conte, Theodore Goldstein, Giorgio Inghirami, Mark A. Murakami, Sebastian Brabetz, Zhiping Gu, Jeffrey A. Wiser, Patrick Dunn, Dale A. Begley, Debra M. Krupke, Andrea Bertotti, Alejandra Bruna, Matthew H. Brush, Annette T. Byrne, Carlos Caldas, Amanda L. Christie, Dominic A. Clark, Heidi Dowst, Jonathan R. Dry, James H. Doroshow, Olivier Duchamp, Yvonne A. Evrard, Stephane Ferretti, Kristopher K. Frese, Neal C. Goodwin, Danielle Greenawalt, Melissa A. Haendel, Els Hermans, Peter J. Houghton, Jos Jonkers, Kristel Kemper, Tin O. Khor, Michael T. Lewis, K.C. Kent Lloyd, Jeremy Mason, Enzo Medico, Steven B. Neuhauser, James M. Olson, Daniel S. Peeper, Oscar M. Rueda, Je Kyung Seong, Livio Trusolino, Emilie Vinolo, Robert J. Wechsler-Reya, David M. Weinstock, Alana Welm, S. John Weroha, Frédéric Amant, Stefan M. Pfister, Marcel Kool, Helen Parkinson, Atul J. Butte, Carol J. Bult
Journal: Cancer Research
Cancer Res (2017) 77 (21): e62–e66.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0582
Published: 31 October 2017
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Includes: Supplementary data
Journal Articles

Abstract 1254: Mechanistic interrogation of pre-treatment low dose aspirin effects in HER 2 positive breast cancer

Ian S. Miller, Sonja Khan, Liam P. Shiels, Sudipto Das, Bruce Moran, Finbarr P. Leacy, Paul M. Loadman, Robert S. Kerbel, Darran O' Connor, Kathleen Bennett, Róisín M. Dwyer, Annette T. Byrne
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1254.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1254
Published: 01 July 2017
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Journal Articles

Abstract 3269: Recapitulating the BETH adjuvant breast cancer trial (NCT00625898) using clinically accurate orthotopic surgical resection models

Liam S. Shiels, Ian S. Miller, Clare Morgan, Mattia Cremona, Robert Kerbel, Bryan Hennessey, Norma O’Donovan, John Crown, Annette T. Byrne
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3269.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3269
Published: 15 July 2016
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Journal Articles

Abstract 3010: Proteomic analysis of off-target toxicities following treatment with the tyrosine kinase inhibitor sunitinib

Alice C. O’Farrell, Adam Lafferty, Ian Miller, Rhys Evans, Maurice Cary, David Murray, Marina Alamanou, Girish Mallya Udupi, Liam Shiels, William M. Gallagher, Annette T. Byrne
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3010.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3010
Published: 15 July 2016
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Journal Articles

Abstract 1828: Analysis of putative serum biomarker candidates for cardiotoxicity prediction in a cohort of early stage breast cancer patients treated with docetaxel, cyclophosphamide, and bevacizumab

David W. Murray, Alice C. O’Farrell, Giuseppe Gullo, Ashwini Maratha, Patrick Dicker, Mairin Rafferty, Verena Murphy, Bonnie Ky, William M. Gallagher, Norma O’Donovan, John Crown, Annette T. Byrne
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1828.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1828
Published: 15 July 2016
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Journal Articles

Abstract 2096: Mechanistic insights into the pathogenesis of anti-DLL4-related hepatic sinusoidal dilatation

Monika A. Jarzabek, Rupal Desai, Yuda Zhu, Christina Z. de Zafra, Joe Beyer, Gary Cain, Rajiv Raja, Annette T. Byrne, Priti Hegde, Jacqueline M. Tarrant
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2096.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2096
Published: 15 July 2016
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Journal Articles

Abstract 5093: Pre-clinical assessment of a novel anti-invasion nanoparticle therapeutic in combination with bevacizumab for the treatment of glioblastoma

David W. Murray, Philip O'Halloran, Monika Jarzabek, Brian MacCarthy, Jann N. Sarkaria, Raymond M. Schiffelers, Marc Symons, Annette T. Byrne
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5093.
DOI: https://doi.org/10.1158/1538-7445.AM2015-5093
Published: 01 August 2015
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Journal Articles

Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors

Sweta Rani, Claire Corcoran, Liam Shiels, Serena Germano, Susan Breslin, Stephen Madden, Martina S. McDermott, Brigid C. Browne, Norma O'Donovan, John Crown, Martina Gogarty, Annette T. Byrne, Lorraine O'Driscoll
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (14): 3821–3833.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2053
Published: 14 July 2014
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Includes: Supplementary data
Journal Articles

Abstract LB-40: Guanine nucleotide exchange factors Dock7 and Ect2 mediate HGF/c-MET-induced glioblastoma cell invasion.

David W. Murray, Sebastien Didier, Vincent M. Paulino, Amanda Chan, Nhan L. Tran, Annette T. Byrne, Marc H. Symons
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-40.
DOI: https://doi.org/10.1158/1538-7445.AM2013-LB-40
Published: 15 April 2013
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Journal Articles

New cell-based assay for comparison of caspase 3/7 activity in normal versus tumor cell populations

Annette T. Byrne, Ian Miller, Mike Hall, Lynne Holmes, Donal F. O’Shea, Colin Wilde, William M. Gallagher
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 321.
Published: 15 April 2006
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