1-20 of 35
Anne Monks
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 270: Temozolomide resistant MGMT negative/MMR proficient cancer cells rely on ATR signaling and homologous recombination for DNA repair and survival

Lara El Touny, Erik Harris, Curtis Hose, John Connelly, Diana Vengsarkar, Anne Monks, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 270.
https://doi.org/10.1158/1538-7445.AM2019-270
Published: 01 July 2019
View article titled, Abstract 270: Temozolomide resistant MGMT negative/MMR proficient cancer cells rely on ATR signaling and homologous recombination for DNA repair and survival
Journal Articles

The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Anne Monks, Yingdong Zhao, Curtis Hose, Hossein Hamed, Julia Krushkal, Jianwen Fang, Dmitriy Sonkin, Alida Palmisano, Eric C. Polley, Laura K. Fogli, Mariam M. Konaté, Sarah B. Miller, Melanie A. Simpson, Andrea Regier Voth, Ming-Chung Li, Erik Harris, Xiaolin Wu, John W. Connelly, Annamaria Rapisarda, Beverly A. Teicher, Richard Simon, James H. Doroshow
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (24): 6807–6817.
https://doi.org/10.1158/0008-5472.CAN-18-0989
Published: 13 December 2018
View article titled, The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel
Open the PDF for The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel in another window
Includes: Supplementary data
Journal Articles

Abstract 1557: Longitudinal expression response of glycosylation related genes, regulators, and targets in cancer cell lines treated with eleven anti-tumor agents

Julia Krushkal, Yingdong Zhao, Curtis Hose, Anne Monks, James H. Doroshow, Richard Simon
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1557.
https://doi.org/10.1158/1538-7445.AM2017-1557
Published: 01 July 2017
View article titled, Abstract 1557: Longitudinal expression response of glycosylation related genes, regulators, and targets in cancer cell lines treated with eleven anti-tumor agents
Journal Articles

Abstract 5178: Determinants of response to temozolomide in an exceptionally sensitive patient derived model

Lara H. el Touny, John Connelly, Curtis Hose, Anne Monks, Mark W. Burkett, Erik Harris, Rene’ M. Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, Thomas Silvers, David Evans, Dianne Newton, Luke Stockwin, Melinda Hollingshead, Ralph Parchment, James H. Doroshow, Beverly Teicher, Annamaria Rapisarda
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5178.
https://doi.org/10.1158/1538-7445.AM2016-5178
Published: 15 July 2016
View article titled, Abstract 5178: Determinants of response to temozolomide in an exceptionally sensitive patient derived model
Journal Articles

Abstract 606: Similar 3D pharmacodynamic (3D-PD) responses of human tumor spheroids and xenografts to topoisomerase 1 inhibitor-induced DNA damage

David M. Evans, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, Silvers Thomas, Robert Kinders, Tony Navas, Scott Lawrence, Anne Monks, Annamaria Rapisarda, Ralph E. Parchment, James H. Doroshow, Beverly Teicher
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 606.
https://doi.org/10.1158/1538-7445.AM2016-606
Published: 15 July 2016
View article titled, Abstract 606: Similar 3D pharmacodynamic (3D-PD) responses of human tumor spheroids and xenografts to topoisomerase 1 inhibitor-induced DNA damage
Journal Articles

Abstract 5406: Osteosarcoma cell lines response to approved and investigational anticancer agents and statins along with gene and microRNA expression

Gurmeet Kaur, Eric Polley, Joel Morris, Thomas Silvers, Michael Selby, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Anne Monks, Annamaria Rapisarda, David Evans, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5406.
https://doi.org/10.1158/1538-7445.AM2015-5406
Published: 01 August 2015
View article titled, Abstract 5406: Osteosarcoma cell lines response to approved and investigational anticancer agents and statins along with gene and microRNA expression
Journal Articles

Abstract 3741: Development and characterization of a cell based assay for the validation of mutant IDH1 inhibitors

Nicole D. Fer, Erik Harris, Stephen Fox, Ming Zhou, Catherine Simpson, Jing Liu, Ilia Korboukh, Emily A. Hull-Ryde, William P. Janzen, Stephen V. Frye, Anne Monks, Beverly Teicher, Annamaria Rapisarda
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3741.
https://doi.org/10.1158/1538-7445.AM2014-3741
Published: 01 October 2014
View article titled, Abstract 3741: Development and characterization of a cell based assay for the validation of mutant IDH1 inhibitors
Journal Articles

Abstract 2361: Identification and analysis of gene fusion and splice variant events in the NCI sarcoma cell line panel

Kazimierz O. Wrzeszczynski, Eric C. Polley, Curtis Hose, Anne Monks, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2361.
https://doi.org/10.1158/1538-7445.AM2014-2361
Published: 01 October 2014
View article titled, Abstract 2361: Identification and analysis of gene fusion and splice variant events in the NCI sarcoma cell line panel
Journal Articles

Abstract 5508: Bromodomain and hegdehog pathway targets in small cell lung cancer

Gurmeet Kaur, Russell A. Reinhart, Anne Monks, David Evans, Joel Morris, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5508.
https://doi.org/10.1158/1538-7445.AM2014-5508
Published: 01 October 2014
View article titled, Abstract 5508: Bromodomain and hegdehog pathway targets in small cell lung cancer
Journal Articles

Abstract 5475: Interrogation of NCI-60 patterns of growth inhibition in conjunction with investigational oncology agents kinase profiling for the elucidation of mechanistic targets

Joel Morris, Mark Kunkel, Eric Polley, Susan Holbeck, Anne Monks, David Evans, Annamaria Rapisarda, Jerry Collins, Beverly Teicher
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5475.
https://doi.org/10.1158/1538-7445.AM2014-5475
Published: 01 October 2014
View article titled, Abstract 5475: Interrogation of NCI-60 patterns of growth inhibition in conjunction with investigational oncology agents kinase profiling for the elucidation of mechanistic targets
Journal Articles

Abstract 5450: Screening more than 60 human SCLC lines with approved and investigational agents indicates complex patterns of response: Identification of HSP90 and HDACs as potential targets

David M. Evans, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, Thomas Silvers, John Connelly, Anne Monks, Eric Polley, Gurmeet Kaur, Joel Morris, Beverly Teicher
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5450.
https://doi.org/10.1158/1538-7445.AM2014-5450
Published: 01 October 2014
View article titled, Abstract 5450: Screening more than 60 human SCLC lines with approved and investigational agents indicates complex patterns of response: Identification of HSP90 and HDACs as potential targets
Journal Articles

Abstract 4361: Target and drug discovery for recalcitrant, rare and neglected cancers.

Anne Monks, Annamaria Rapisarda, Kazimierz O. Wrzeszczynski, E. Michael August, Eric C. Polley, Sudhir B. Kondapaka, Gurmeet Kaur, Dianne Newton, Beverley A. Teicher
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4361.
https://doi.org/10.1158/1538-7445.AM2013-4361
Published: 15 April 2013
View article titled, Abstract 4361: Target and drug discovery for recalcitrant, rare and neglected cancers.
Journal Articles

Abstract 2116: CHEK2 (Chk2) endogenous activation is associated with p53 deficiency and downregulation of BRCA2 and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60)

Gabriele Zoppoli, Stéphanie Solier, William C. Reinhold, Hongfang Liu, John W. Connelly, Anne Monks, Robert H. Shoemaker, Ogan D. Abaan, Sean R. Davis, Daniela Piras, Alberto Ballestrero, Paul S. Meltzer, James H. Doroshow, Yves Pommier
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2116.
https://doi.org/10.1158/1538-7445.AM2012-2116
Published: 15 April 2012
View article titled, Abstract 2116: <em>CHEK2</em> (Chk2) endogenous activation is associated with p53 deficiency and downregulation of <em>BRCA2</em> and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60)
Journal Articles

Abstract 5663: Confirmation of peroxiredoxin II as a driver gene for doxorubicin sensitivity identified from drug-induced expression profiling of the NCI-60 cell lines using Reverse Engineering (REFS) network models

Anne Monks, Curtis D. Hose, Boris Hayete, Karl Runge, David DeCaprio, Beverley A. Teicher, Iya Khalil, Paul McDonaugh, James H. Doroshow
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5663.
https://doi.org/10.1158/1538-7445.AM2012-5663
Published: 15 April 2012
View article titled, Abstract 5663: Confirmation of peroxiredoxin II as a driver gene for doxorubicin sensitivity identified from drug-induced expression profiling of the NCI-60 cell lines using Reverse Engineering (REFS) network models
Journal Articles

Abstract 2853: Sunitinib induces anti-angiogenic splice-variant VEGF165b through induction of CLK1 and CLK4 kinases in prostate cell line DU-145

Anne Monks, Curtis D. Hose, James H. Doroshow
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2853.
https://doi.org/10.1158/1538-7445.AM2011-2853
Published: 15 April 2011
View article titled, Abstract 2853: Sunitinib induces anti-angiogenic splice-variant VEGF165b through induction of CLK1 and CLK4 kinases in prostate cell line DU-145
Journal Articles

Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts in vivo

Michael C. Alley, Melinda G. Hollingshead, Suzanne D. Borgel, Kevin Plater, Mark W. Burkett, Miriam R. Anver, Brandon R. Yen, Karen M. Hite, Dominic A. Scudiero, Anne Monks, Susan D. Mertins, Robert H. Shoemaker, John E. Niederhuber
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5202.
https://doi.org/10.1158/1538-7445.AM2011-5202
Published: 15 April 2011
View article titled, Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts <em>in vivo</em>
Journal Articles

Abstract 1103: Linkage between endogenous Chk2 activation and p14ARF expression in p53-mutated cells revealed by proteomic and genomic analyses of the NCI60

Gabriele M. Zoppoli, William C. Reinhold, Stephanie Solier, Anne Monks, John W. Connelly, Hongfang Liu, Kurt W. Kohn, Robert Shoemaker, Yves Pommier
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1103.
https://doi.org/10.1158/1538-7445.AM10-1103
Published: 15 April 2010
View article titled, Abstract 1103: Linkage between endogenous Chk2 activation and p14ARF expression in p53-mutated cells revealed by proteomic and genomic analyses of the NCI60
Journal Articles

Abstract #2426: Genomic taxonomy of anti-cancer drug activity: Profiling of doxorubicin-induced gene expression changes in the NCI-60 cancer cell line panel.

Anne Monks, Curtis Hose, Jinghui Zhang, Xiaolin Wu, Sharon Greenblum, Ying Hu, Robert Clifford, Jerry Collins, Kenneth Buetow, James Doroshow
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2426.
Published: 01 May 2009
View article titled, Abstract #2426: Genomic taxonomy of anti-cancer drug activity: Profiling of doxorubicin-induced gene expression changes in the NCI-60 cancer cell line panel.
Journal Articles

Abstract #4616: Evaluation of NSC83265: Histone H3, BubR1 and monoastral formation are potential pharmacodynamic biomarkers.

Gurmeet Kaur, Sadie Frary, Susan Holbeck, Anne Monks, Melinda Hollingshead
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4616.
Published: 01 May 2009
View article titled, Abstract #4616: Evaluation of NSC83265: Histone H3, BubR1 and monoastral formation are potential pharmacodynamic biomarkers.
Journal Articles

Abstract #2424: Doxorubicin induces activation of p53 pathway in sensitive NCI-60 cell lines that have the composite genotype of wild-type p53and mutant p16

Jinghui Zhang, Sharon Greenblum, Robert Clifford, Ying Hu, Anne Monks, Curtis Hose, Jerry Collins, Xiaolin Wu, James Doroshow, Kenneth Buetow
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2424.
Published: 01 May 2009
View article titled, Abstract #2424: Doxorubicin induces activation of p53 pathway in sensitive NCI-60 cell lines that have the composite genotype of wild-type p53<sup></sup>and mutant p16