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Anna Tsimelzon
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Journal Articles

Abstract 22: The Y537S ESR1 mutation is a dominant driver of distant ER-positive breast cancer metastasis

Guowei Gu, Lin Tian, Meng Gao, Yassine Rechoum, Luca Gelsomino, Derek Dustin, Arnoldo Corona-Rodriguez, Amanda R. Beyer, Anna Tsimelzon, Xiang Zhang, Sebastiano Ando', Suzanne Fuqua
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 22.
https://doi.org/10.1158/1538-7445.AM2018-22
Published: 01 July 2018
View articletitled, Abstract 22: The Y537S ESR1 mutation is a dominant driver of distant ER-positive breast cancer metastasis
Journal Articles

Abstract 5525: Induced expression of PPM1A in ER-negative breast cancer cells inhibits growth by suppressing CDK phosphorylation

Abhijit Mazumdar, Jamal Hill, Yun Zhang, Lakshmi Reddy Bollu, Anna Tsimelzon, Jenny Chang, Gordon Mills, Powel Brown
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5525.
https://doi.org/10.1158/1538-7445.AM2017-5525
Published: 01 July 2017
View articletitled, Abstract 5525: Induced expression of PPM1A in ER-negative breast cancer cells inhibits growth by suppressing CDK phosphorylation
Journal Articles

Abstract 2913: The SOX11 transcription factor is critical for basal-like breast cancer growth and migration and is associated with poor survival

Jonathan Shepherd, Abhijit Mazumdar, Anna Tsimelzon, Susan G. Hilsenbeck, Powel H. Brown
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2913.
https://doi.org/10.1158/1538-7445.AM2016-2913
Published: 15 July 2016
View articletitled, Abstract 2913: The SOX11 transcription factor is critical for basal-like breast cancer growth and migration and is associated with poor survival
Journal Articles

Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival

Petra den Hollander, Kathryn Rawls, Anna Tsimelzon, Jonathan Shepherd, Abhijit Mazumdar, Jamal Hill, Suzanne A.W. Fuqua, Jenny C. Chang, C. Kent Osborne, Susan G. Hilsenbeck, Gordon B. Mills, Powel H. Brown
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1942–1953.
https://doi.org/10.1158/0008-5472.CAN-14-0673
Published: 31 March 2016
View articletitled, Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival
Open the PDF for Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival in another window
Includes: Supplementary data
Journal Articles

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Bryan C. Nikolai, Rainer B. Lanz, Brian York, Subhamoy Dasgupta, Nicholas Mitsiades, Chad J. Creighton, Anna Tsimelzon, Susan G. Hilsenbeck, David M. Lonard, Carolyn L. Smith, Bert W. O'Malley
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1463–1475.
https://doi.org/10.1158/0008-5472.CAN-15-2383
Published: 14 March 2016
View articletitled, HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes
Open the PDF for HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes in another window
Includes: Supplementary data
Journal Articles

Abstract 5279: Induced expression of PPM1A in ER-negative breast cancer cells inhibits growth by suppressing cell cycle

Abhijit Mazumdar, Graham Poage, Jamal Hill, Yun Zhang, Anna Tsimelzon, Jenny Chang, Gordon Mills, Powel Brown
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5279.
https://doi.org/10.1158/1538-7445.AM2014-5279
Published: 01 October 2014
View articletitled, Abstract 5279: Induced expression of PPM1A in ER-negative breast cancer cells inhibits growth by suppressing cell cycle
Journal Articles

Abstract 3299: Maternal embryonic leucine zipper kinase is critical for the growth and migration of triple negative breast cancer cells

Nidhi Batra, Corey Speers, Ivan Uray, Abhijit Mazumdar, Anna Tsimelzon, Susan Hilsenbeck, Gordon Mills, Powel Brown
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3299.
https://doi.org/10.1158/1538-7445.AM2014-3299
Published: 01 October 2014
View articletitled, Abstract 3299: Maternal embryonic leucine zipper kinase is critical for the growth and migration of triple negative breast cancer cells
Journal Articles

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

Xiaomei Zhang, Sofie Claerhout, Aleix Prat, Lacey E. Dobrolecki, Ivana Petrovic, Qing Lai, Melissa D. Landis, Lisa Wiechmann, Rachel Schiff, Mario Giuliano, Helen Wong, Suzanne W. Fuqua, Alejandro Contreras, Carolina Gutierrez, Jian Huang, Sufeng Mao, Anne C. Pavlick, Amber M. Froehlich, Meng-Fen Wu, Anna Tsimelzon, Susan G. Hilsenbeck, Edward S. Chen, Pavel Zuloaga, Chad A. Shaw, Mothaffar F. Rimawi, Charles M. Perou, Gordon B. Mills, Jenny C. Chang, Michael T. Lewis
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (15): 4885–4897.
https://doi.org/10.1158/0008-5472.CAN-12-4081
Published: 31 July 2013
View articletitled, A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Open the PDF for A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models in another window
Includes: Supplementary data
Journal Articles

Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8

Zachary C. Hartman, Graham M. Poage, Petra den Hollander, Anna Tsimelzon, Jamal Hill, Nattapon Panupinthu, Yun Zhang, Abhijit Mazumdar, Susan G. Hilsenbeck, Gordon B. Mills, Powel H. Brown
Journal: Cancer Research
Cancer Res (2013) 73 (11): 3470–3480.
https://doi.org/10.1158/0008-5472.CAN-12-4524-T
Published: 30 May 2013
View articletitled, Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Open the PDF for Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8 in another window
Includes: Supplementary data
Journal Articles

Abstract 856: High expression of DUSP4 in ER-negative breast cancer cells suppresses growth and invasion.

Abhijit Mazumdar, Petra Den Hollander, Graham Poage, Jamal Hill, Yun Zhang, Anna Tsimelzon, Susan Hilsenbeck, Jenny Chang, Gordon Mills, Powel H. Brown
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 856.
https://doi.org/10.1158/1538-7445.AM2013-856
Published: 15 April 2013
View articletitled, Abstract 856: High expression of DUSP4 in ER-negative breast cancer cells suppresses growth and invasion.
Journal Articles

Abstract 3124: Identification of transcription factors critical for the growth of basal-like breast cancer.

Jonathan Shepherd, Ivan P. Uray, Abhijit Mazumdar, Anna Tsimelzon, Susan G. Hilsenbeck, Powel H. Brown
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3124.
https://doi.org/10.1158/1538-7445.AM2013-3124
Published: 15 April 2013
View articletitled, Abstract 3124: Identification of transcription factors critical for the growth of basal-like breast cancer.
Journal Articles

Abstract 1996: Identification of four subgroups of Triple Negative Breast Cancer (TNBC) by genomic profiling.

Matthew D. Burstein, Anna Tsimelzon, Kyle R. Covington, Suzanne AW Fuqua, Jenny C. Chang, Susan G. Hilsenbeck, C Kent Osborne, Gordon B. Mills, Ching C. Lau, Powel H. Brown
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1996.
https://doi.org/10.1158/1538-7445.AM2013-1996
Published: 15 April 2013
View articletitled, Abstract 1996: Identification of four subgroups of Triple Negative Breast Cancer (TNBC) by genomic profiling.
Journal Articles

Abstract 2853: Discovery of phosphatases that regulate growth and tumorigenicity of ER-negative breast cancers

Petra den Hollander, Abhijit Mazumdar, Anna Tsimelzon, Susan Hilsenbeck, Jenny Chang, Gordon Mills, Powel Brown
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2853.
https://doi.org/10.1158/1538-7445.AM2012-2853
Published: 15 April 2012
View articletitled, Abstract 2853: Discovery of phosphatases that regulate growth and tumorigenicity of ER-negative breast cancers
Journal Articles

Abstract 2857: Induced expression of DUSP4 and PPM1A in ER-negative breast cancer cells suppresses proliferation and invasion

Abhijit Mazumdar, Petra Den Hollander, Anna Tsimelzon, Susan Hilsenbeck, Jenny Chang, Gordon Mills, Powel Brown
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2857.
https://doi.org/10.1158/1538-7445.AM2012-2857
Published: 15 April 2012
View articletitled, Abstract 2857: Induced expression of DUSP4 and PPM1A in ER-negative breast cancer cells suppresses proliferation and invasion
Journal Articles

Abstract 4862: Autocrine secreted IL-6 and IL-8 play critical and non-redundant roles in basal-like breast cancer cell transformation and growth in vitro and in vivo

Zachary C. Hartman, Anna Tsimelzon, Ivan P. Uray, Jamal Hill, Yun Zhang, Abhijit Mazumdar, Susan G. Hilsenbeck, Jenny Chang, Gordon B. Mills, Powel H. Brown
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4862.
https://doi.org/10.1158/1538-7445.AM2012-4862
Published: 15 April 2012
View articletitled, Abstract 4862: Autocrine secreted IL-6 and IL-8 play critical and non-redundant roles in basal-like breast cancer cell transformation and growth in vitro and in vivo
Journal Articles

Abstract 1664: Maternal embryonic leucine aipper kinase (MELK) is a critical regulator of proliferation and is independently prognostic in estrogen receptor-negative breast cancer

Karrie Wheatley, Corey Speers, Anna Tsimelzon, Krystal Sexton, Susan Hilsenbeck, Jenny Chang, Powel Brown
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1664.
https://doi.org/10.1158/1538-7445.AM2011-1664
Published: 15 April 2011
View articletitled, Abstract 1664: Maternal embryonic leucine aipper kinase (MELK) is a critical regulator of proliferation and is independently prognostic in estrogen receptor-negative breast cancer
Journal Articles

Abstract 1665: Targeting phosphatases for the treatment of ER-negative breast cancer

Abhijit Mazumdar, Corey Speers, Chunyu Wang, Anna Tsimelzon, Susan Hilsenbeck, Powel Brown
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1665.
https://doi.org/10.1158/1538-7445.AM2011-1665
Published: 15 April 2011
View articletitled, Abstract 1665: Targeting phosphatases for the treatment of ER-negative breast cancer
Journal Articles

Abstract 2296: Identification of novel nuclear receptor targets in estrogen receptor negative breast cancer

Kyle R. Covington, Guowei Gu, Anna Tsimelzon, Susan Hilsenbeck, Powel Brown, Jenny Change, C Kent Osborne, Jianming Xu, Bert O'Malley, David Mangelsdorf, John Minna, Suzanne Fuqua
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2296.
https://doi.org/10.1158/1538-7445.AM2011-2296
Published: 15 April 2011
View articletitled, Abstract 2296: Identification of novel nuclear receptor targets in estrogen receptor negative breast cancer
Journal Articles

Abstract 4133: Comparative gene expression and proteomic analysis of IGF-I and insulin signaling in a large panel of breast cancer cell lines

Yu-Fen Wang, Beate Litzenburger, Isere Kuiatse, Robert K. Dearth, Angelo J. Casa, Anna Tsimelzon, Susan G. Hilsenbeck, Jie Li, Bryan T. Hennessey, Gordon B. Mills, Motharffar F. Rimawi, Adrian V. Lee
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4133.
https://doi.org/10.1158/1538-7445.AM10-4133
Published: 15 April 2010
View articletitled, Abstract 4133: Comparative gene expression and proteomic analysis of IGF-I and insulin signaling in a large panel of breast cancer cell lines
Journal Articles

Abstract #4990: MTA2 overexpression enhances metastasis and alters cell adhesion in breast cancer

Kyle Covington, Yukun Cui, Ines Barone, Arnoldo Corona-Rodriguez, Anna Tsimelzon, Tao Wang, Suzanne Fuqua
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4990.
Published: 01 May 2009
View articletitled, Abstract #4990: MTA2 overexpression enhances metastasis and alters cell adhesion in breast cancer