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Anna M. Wu
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Journal Articles

Abstract 6021: Lutetium-177 (177Lu) radiolabeled engineered antibody fragment against human prostate stem cell antigen (hPSCA) demonstrates targeting and antitumor effects in a syngeneic mouse model of pancreatic ductal adenocarcinoma (PDAC)

Bao Ying Chen, Masoud Farshbaf, Felix B. Salazar, Saad N. Ahmed, Sunidhi Jaiswal, Jennifer Chean, Anakim Sherman, Teresa Hong, Paul J. Yazaki, Tove Olafsen, Kirstin A. Zettlitz, Anna M. Wu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6021.
https://doi.org/10.1158/1538-7445.AM2024-6021
Published: 22 March 2024
View article titled, Abstract 6021: Lutetium-177 (<sup>177</sup>Lu) radiolabeled engineered antibody fragment against human prostate stem cell antigen (hPSCA) demonstrates targeting and antitumor effects in a syngeneic mouse model of pancreatic ductal adenocarcinoma (PDAC)
Journal Articles

Abstract A088: Radiopharmaceutical therapy for pancreatic cancer: Engineered anti-prostate stem cell antigen (PSCA) antibody demonstrates targeted imaging and antitumor effects in a syngeneic mouse model of pancreatic ductal adenocarcinoma (PDAC)

Bao Ying Chen, Saad N. Ahmed, Felix Salazar, Sunidhi Jaiswal, Masoud Farshbaf, Jennifer Chean, Anakim Sherman, Teresa Hong, Paul J. Yazaki, Tove Olafsen, Kirstin A. Zettlitz, Anna M. Wu
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A088.
https://doi.org/10.1158/1538-7445.PANCA2023-A088
Published: 16 January 2024
View article titled, Abstract A088: Radiopharmaceutical therapy for pancreatic cancer: Engineered anti-prostate stem cell antigen (PSCA) antibody demonstrates targeted imaging and antitumor effects in a syngeneic mouse model of pancreatic ductal adenocarcinoma (PDAC)
Journal Articles

Abstract 5372: CD3 and CD8 targeting of ionizable lipid nanoparticles for in vivo mRNA delivery to T cells

Elise R. Robinson, Aris J. Kare, Azadeh Kheirolomoom, Mohammed Inayathullah, Spencer K. Tumbale, Bo Wu, Marina N. Raie, Jai W. Seo, Felix B. Salazar, Ramasamy Paulmurugan, Anna M. Wu, Katherine W. Ferrara
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5372.
https://doi.org/10.1158/1538-7445.AM2022-5372
Published: 15 June 2022
View article titled, Abstract 5372: CD3 and CD8 targeting of ionizable lipid nanoparticles for <em>in vivo</em> mRNA delivery to T cells
Journal Articles

Abstract 1502: Pre-conditioning modifies the tumor microenvironment to enhance solid tumor CAR T cell efficacy and endogenous immunity

John P. Murad, Dileshni Tilakawardane, Anthony K. Park, Kelly T. Kennewick, Lupita S. Lopez, Hee J. Lee, Brenna J. Gittins, Wen-Chung Chang, Chau P. Tran, Catalina Martinez, Anna M. Wu, Robert E. Reiter, Tanya B. Dorff, Stephen J. Forman, Saul J. Priceman
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1502.
https://doi.org/10.1158/1538-7445.AM2021-1502
Published: 01 July 2021
View article titled, Abstract 1502: Pre-conditioning modifies the tumor microenvironment to enhance solid tumor CAR T cell efficacy and endogenous immunity
Journal Articles

Sanjiv “Sam” Gambhir, MD, PhD: In Memoriam (1962–2020)

Anna M. Wu, Andrei Iagaru, Harvey Herschman, Ralph Weissleder, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4305–4306.
https://doi.org/10.1158/0008-5472.CAN-20-2856
Published: 15 October 2020
View article titled, Sanjiv “Sam” Gambhir, MD, PhD: In Memoriam (1962–2020)
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Journal Articles

Abstract 1856: Dual-modality immunoPET/fluorescence imaging of prostate cancer utilizing 89Zr- or 124I-Cy5.5-anti-PSCA cys-minibody

Wen-Ting K. Tsai, Kirstin A. Zettlitz, Richard Tavaré, Felix B. Salazar, Robert E. Reiter, Anna M. Wu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1856.
https://doi.org/10.1158/1538-7445.AM2017-1856
Published: 01 July 2017
View article titled, Abstract 1856: Dual-modality immunoPET/fluorescence imaging of prostate cancer utilizing <sup>89</sup>Zr- or <sup>124</sup>I-Cy5.5-anti-PSCA cys-minibody
Journal Articles

An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy

Richard Tavaré, Helena Escuin-Ordinas, Stephen Mok, Melissa N. McCracken, Kirstin A. Zettlitz, Felix B. Salazar, Owen N. Witte, Antoni Ribas, Anna M. Wu
Journal: Cancer Research
Cancer Res (2016) 76 (1): 73–82.
https://doi.org/10.1158/0008-5472.CAN-15-1707
Published: 03 January 2016
View article titled, An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy
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Includes: Supplementary data
Journal Articles

Abstract LB-163: Development of an immunoPET tracer for imaging human CD8+ T cells

Tove Olafsen, David Ho, Eric Epin, Green Zhang, Michael Torgov, Charlie Beigarten, Giti Agahi, Edward Cabral, Anna M. Wu, Jean M. Gudas
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-163.
https://doi.org/10.1158/1538-7445.AM2014-LB-163
Published: 01 October 2014
View article titled, Abstract LB-163: Development of an immunoPET tracer for imaging human CD8+ T cells
Journal Articles

Abstract 4300: Receptor occupancy and tumor penetration by antibodies, peptides, and antibody fragments: Molecular simulation of imaging assessment

Kelly D. Orcutt, Gregory P. Adams, Anna M. Wu, Matthew Silva, Jack Hoppin, Catey Harwell, Manabu Matsumura, Masakatsu Kotsuma, Daniel Freeman, Archie Tse, Jonathan Greenberg, Andrew Scott, Robert A. Beckman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4300.
https://doi.org/10.1158/1538-7445.AM2014-4300
Published: 01 October 2014
View article titled, Abstract 4300: Receptor occupancy and tumor penetration by antibodies, peptides, and antibody fragments: Molecular simulation of imaging assessment
Journal Articles

Abstract 4283: Evaluation of PSCA-specific minibody for in vivo imaging

Chau P. Tran, Scott Knowles, Tove Olafsen, Eric J. Lepin, Anna M. Wu, Robert E. Reiter
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4283.
https://doi.org/10.1158/1538-7445.AM2011-4283
Published: 15 April 2011
View article titled, Abstract 4283: Evaluation of PSCA-specific minibody for in vivo imaging
Journal Articles

Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy

Vania Kenanova, Tove Olafsen, Lawrence E. Williams, Nora H. Ruel, Jeffrey Longmate, Paul J. Yazaki, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2007) 67 (2): 718–726.
https://doi.org/10.1158/0008-5472.CAN-06-0454
Published: 18 January 2007
View article titled, Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy
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Journal Articles

Optimizing Radiolabeled Engineered Anti-p185HER2 Antibody Fragments for In vivo Imaging

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Desiree Crow, Paul J. Yazaki, Lin Li, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Jeffrey Y.C. Wong, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5907–5916.
https://doi.org/10.1158/0008-5472.CAN-04-4472
Published: 01 July 2005
View article titled, Optimizing Radiolabeled Engineered Anti-p185<sup>HER2</sup> Antibody Fragments for <em>In vivo</em> Imaging
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Includes: Supplementary data
Journal Articles

Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties

Vania E. Kenanova, Tove Olafsen, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Lawrence E. Williams, John E. Shively, David Colcher, Sanjiv S. Gambhir, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1243.
Published: 01 May 2005
View article titled, Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties
Journal Articles

Biological activity and microPET imaging properties of chimeric and humanized anti-prostate stem cell antigen (PSCA) antibodies

Zhennan Gu, Tove Olafsen, Mark Sherman, Sherie L. Morrison, Anna M. Wu, Robert E. Reiter
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 164.
Published: 01 May 2005
View article titled, Biological activity and microPET imaging properties of chimeric and humanized anti-prostate stem cell antigen (PSCA) antibodies
Journal Articles

MicroPET imaging of breast cancer xenografts with anti-p185HER2 minibody and scFv-Fc antibody fragments

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 899–900.
Published: 01 May 2005
View article titled, MicroPET imaging of breast cancer xenografts with anti-p185<sup>HER2</sup> minibody and scFv-Fc antibody fragments
Journal Articles

Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments

Vania Kenanova, Tove Olafsen, Desiree M. Crow, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Nora H. Carter, David N. Ikle, Paul J. Yazaki, Arion F. Chatziioannou, Sanjiv S. Gambhir, Lawrence E. Williams, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (2): 622–631.
https://doi.org/10.1158/0008-5472.622.65.2
Published: 03 February 2005
View article titled, Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments
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Journal Articles

Optical Bioluminescence and Positron Emission Tomography Imaging of a Novel Fusion Reporter Gene in Tumor Xenografts of Living Mice

Pritha Ray, Anna M. Wu, Sanjiv S. Gambhir
Journal: Cancer Research
Cancer Res (2003) 63 (6): 1160–1165.
Published: 15 March 2003
View article titled, Optical Bioluminescence and Positron Emission Tomography Imaging of a Novel Fusion Reporter Gene in Tumor Xenografts of Living Mice
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Journal Articles

Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-CH3) Which Exhibits Rapid, High-Level Targeting of Xenografts

Shi-zhen Hu, Louise Shively, Andrew Raubitschek, Mark Sherman, Lawrence E. Williams, Jeffrey Y. C. Wong, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (1996) 56 (13): 3055–3061.
Published: 01 July 1996
View article titled, Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-C<sub>H</sub>3) Which Exhibits Rapid, High-Level Targeting of Xenografts
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Journal Articles

Initial Experience Evaluating 90Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial

Jeffrey Y. C. Wong, Lawrence E. Williams, David M. Yamauchi, Tamara Odom-Maryon, Jose M. Esteban, Michael Neumaier, Anna M. Wu, David K. Johnson, F. James Primus, John E. Shively, Andrew A. Raubitschek
Journal: Cancer Research
Cancer Res (1995) 55 (23_Supplement): 5929s–5934s.
Published: 01 December 1995
View article titled, Initial Experience Evaluating <sup>90</sup>Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial
Open the PDF for Initial Experience Evaluating <sup>90</sup>Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial in another window