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Abstract 2421: Elucidation of CSF1 autocrine signaling mediated by mutant p53 in metastatic esophageal carcinoma

Gizem Efe, Qiaosi Tang, Ricardo Cruz-Acuna, Kensuke Suzuki, Kensuke Sugiura, Joel Gabre, Uma Sachdeva, Wei Gu, Carol L. Prives, Anil K. Rustgi

Cancer Res (2022) 82 (12_Supplement): 2421.

DOI: https://doi.org/10.1158/1538-7445.AM2022-2421

Published: 15 June 2022

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Journal Articles

Abstract 788: Prrx1 regulates acinar cell plasticity in Kras-driven pancreatic acinar-to-ductal metaplasia

Alina L. Li, Kensuke Sugiura, Kensuke Suzuki, Jason R. Pitarresi, Anna M. Chiarella, Gizem Efe, Rohit Chandwani, Anil K. Rustgi

Cancer Res (2022) 82 (12_Supplement): 788.

DOI: https://doi.org/10.1158/1538-7445.AM2022-788

Published: 15 June 2022

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Journal Articles

Abstract 3838: Engineered hydrogel elucidates contributions of matrix mechanics to esophageal adenocarcinoma and identify matrix-activated therapeutic targets

Ricardo Cruz-Acuña, Secunda W. Kariuki, Claudia Loebel, Tatiana Karakasheva, Joel T. Gabre, Jason A. Burdick, Anil K. Rustgi

Cancer Res (2022) 82 (12_Supplement): 3838.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3838

Published: 15 June 2022

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Journal Articles

Abstract PO-075: The elucidation of the role of Prrx1 for acinar to ductal metaplasia in response to acute injury of pancreas in the novel mouse models

Kensuke Suzuki, Alina Li, Jason R. Pitarresi, Anna M. Chiarella, Gizem Efe, Kensuke Sugiura, Rohit Chandwani, Anil K. Rustgi

Cancer Res (2021) 81 (22_Supplement): PO-075.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PO-075

Published: 15 November 2021

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Journal Articles

Abstract PR-001: Ex vivo co-culture system with patient-derived organoids to assess CXCR4 inhibitor as an immune modulating agent for human pancreas adenocarcinoma

Emily Alouani, Ilenia Pellicciotta, Winston Wong, Alexander S. Thomas, Michael D. Kluger, Anna M. Chiarella, Anil K. Rustgi, Gulam A. Manji

Cancer Res (2021) 81 (22_Supplement): PR-001.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PR-001

Published: 15 November 2021

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Journal Articles

Abstract PR-005: Chromatin dynamics in vivo define coordinate functions of inflammation and mutant Kras in pancreatic tumorigenesis

David Falvo, Jason Pitarresi, Alexa Osterhoudt, Adrien Grimont, Ben Stanger, Steven D. Leach, Anil K. Rustgi, Rohit Chandwani

Cancer Res (2021) 81 (22_Supplement): PR-005.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PR-005

Published: 15 November 2021

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Journal Articles

Abstract PO-106: The extrinsic and modulatory effects of CSF-1/CSF-1R signaling in generating an immunosuppressive pancreatic cancer tumor microenvironment and promoting metastasis

Gizem Efe, Kensuke Suzuki, Jason R. Pitarresi, Anna M. Chiarella, Alina L. Li, Anil K. Rustgi

Cancer Res (2021) 81 (22_Supplement): PO-106.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PO-106

Published: 15 November 2021

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Journal Articles

Abstract PR-010: Collateral amplification of the KRAS linked gene PTHLH governs pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Jason R. Pitarresi, Robert J. Norgard, Anna M. Chiarella, Kensuke Suzuki, Richard Kremer, Ben Z. Stanger, Anil K. Rustgi

Cancer Res (2021) 81 (22_Supplement): PR-010.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PR-010

Published: 15 November 2021

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Journal Articles

Abstract 2691: Extracellular adenosine signaling in pancreatic cancer: New therapeutic strategies

Anna M. Chiarella, Jason R. Pitarresi, Gulam Manji, Anil K. Rustgi

Cancer Res (2021) 81 (13_Supplement): 2691.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2691

Published: 01 July 2021

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Journal Articles

Abstract 2861: Collateral amplification KRAS-PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Jason Robert Pitarresi, Robert J. Norgard, Anna M. Chiarella, Richard Kremer, Ben Z. Stanger, Anil K. Rustgi

Cancer Res (2021) 81 (13_Supplement): 2861.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2861

Published: 01 July 2021

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Journal Articles

Abstract PR003: Fibroblast plasticity driven by Prrx1 interferes the tumor cells - tumor microenvironment crosstalk towards a more aggressive pancreatic ductal adenocarcinoma

Karin Feldmann, Carlo Maurer, Katja Peschke, Steffen Teller, Kathleen Schuck, Katja Steiger, Thomas Engleitner, Rupert Öllinger, Aristeidis Papargyriou, Rim Sabrina Jahan Sarker, Wilko Weichert, Anil K. Rustgi, Roland M. Schmid, Roland Rad, Günter Schneider, Dieter Saur, Maximilian Reichert

Cancer Res (2021) 81 (5_Supplement): PR003.

DOI: https://doi.org/10.1158/1538-7445.TME21-PR003

Published: 01 March 2021

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Journal Articles

Abstract PO-057: Collateral amplification of the PTHrP gene drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Jason R. Pitarresi, Robert J. Norgard, Anna M. Chiarella, Richard Kremer, Ben Z. Stanger, Anil K. Rustgi

Cancer Res (2020) 80 (22_Supplement): PO-057.

DOI: https://doi.org/10.1158/1538-7445.PANCA20-PO-057

Published: 13 November 2020

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Journal Articles

Abstract PO-026: The mitochondrial calcium uniporter contributes to PDAC development and invasion

Jillian S. Weissenrieder, Jason R. Pitarresi, Emily Fernandez-Garcia, Ben Z. Stanger, Anil K. Rustgi, J. Kevin Foskett

Cancer Res (2020) 80 (22_Supplement): PO-026.

DOI: https://doi.org/10.1158/1538-7445.PANCA20-PO-026

Published: 13 November 2020

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Journal Articles

Abstract 501: Aldh2 mutation promotes oral and esophageal cancer stem cells via autophagy-mediated redox homeostasis

Masataka Shimonosono, Takashi Kijima, Hisatsugu Maekawa, Satoshi Takada, Koji Tanaka, Varun Sahu, Manti Guha, Andres J. Klein-Szanto, J. Alan Diehl, Adam J. Bass, Anil K. Rustgi, Elizabeth Philipone, Angela J. Yoon, Hiroshi Nakagawa

Cancer Res (2020) 80 (16_Supplement): 501.

DOI: https://doi.org/10.1158/1538-7445.AM2020-501

Published: 15 August 2020

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Journal Articles

Abstract B38: Calcium signaling induces a partial EMT in pancreatic ductal adenocarcinoma

Robert J. Norgard, Ravikanth Maddipati, Nicole M. Aiello, David Balli, Jason R. Pitarresi, Derick N. Rosario-Berrios, Jinyang Li, Salina Yuan, Taiji Yamazoe, Yogev Sela, Allyson J. Merrell, Maximilian D. Wengyn, Kathryn Sun, Anil K. Rustgi, Ben Z. Stanger

Cancer Res (2019) 79 (24_Supplement): B38.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-B38

Published: 13 December 2019

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Journal Articles

Abstract B43: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of PTHrP-mediated calcium signaling

Jason R. Pitarresi, Robert J. Norgard, Ben Z. Stanger, Anil K. Rustgi

Cancer Res (2019) 79 (24_Supplement): B43.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-B43

Published: 13 December 2019

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Journal Articles

IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment

Cancer Res (2018) 78 (17): 4957–4970.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-2268

Published: 04 September 2018

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Includes: Supplementary data

Journal Articles

Abstract 4713: BET bromodomain inhibition synergizes with PD-1 blockade to facilitate anti-tumor response in Kras-mutant non-small cell lung cancer

Dennis O. Adeegbe, Shengwu Liu, Michaela Bowden, Peter S. Hammerman, James E. Bradner, Anil K. Rustgi, Adam J. Bass, Gordon J. Freeman, Huawei Chen, kwok-Kin Wong

Cancer Res (2018) 78 (13_Supplement): 4713.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4713

Published: 01 July 2018

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Journal Articles

Abstract PR04: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of calcium signaling

Jason R. Pitarresi, Maximilian Reichert, Basil Bakir, Leticia Moreira, Lauren Simon, Anil K. Rustgi

Cancer Res (2018) 78 (10_Supplement): PR04.

DOI: https://doi.org/10.1158/1538-7445.MOUSEMODELS17-PR04

Published: 14 May 2018

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Journal Articles

Abstract 5503: Interplay between the transcription factors PRRX1 and FOXM1 in pancreatic cancer

Benoit Marchand, Maximilian Reichert, Meredith A. Collins, Anil K. Rustgi

Cancer Res (2017) 77 (13_Supplement): 5503.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5503

Published: 01 July 2017

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2 3 4

NARROW

Abstract 2421: Elucidation of CSF1 autocrine signaling mediated by mutant p53 in metastatic esophageal carcinoma

Abstract 788: Prrx1 regulates acinar cell plasticity in Kras-driven pancreatic acinar-to-ductal metaplasia

Abstract 3838: Engineered hydrogel elucidates contributions of matrix mechanics to esophageal adenocarcinoma and identify matrix-activated therapeutic targets

Abstract PO-075: The elucidation of the role of Prrx1 for acinar to ductal metaplasia in response to acute injury of pancreas in the novel mouse models

Abstract PR-001: Ex vivo co-culture system with patient-derived organoids to assess CXCR4 inhibitor as an immune modulating agent for human pancreas adenocarcinoma

Abstract PR-005: Chromatin dynamics in vivo define coordinate functions of inflammation and mutant Kras in pancreatic tumorigenesis

Abstract PO-106: The extrinsic and modulatory effects of CSF-1/CSF-1R signaling in generating an immunosuppressive pancreatic cancer tumor microenvironment and promoting metastasis

Abstract PR-010: Collateral amplification of the KRAS linked gene PTHLH governs pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Abstract 2691: Extracellular adenosine signaling in pancreatic cancer: New therapeutic strategies

Abstract 2861: Collateral amplification KRAS-PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Abstract PR003: Fibroblast plasticity driven by Prrx1 interferes the tumor cells - tumor microenvironment crosstalk towards a more aggressive pancreatic ductal adenocarcinoma

Abstract PO-057: Collateral amplification of the PTHrP gene drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability

Abstract PO-026: The mitochondrial calcium uniporter contributes to PDAC development and invasion

Abstract 501: Aldh2 mutation promotes oral and esophageal cancer stem cells via autophagy-mediated redox homeostasis

Abstract B38: Calcium signaling induces a partial EMT in pancreatic ductal adenocarcinoma

Abstract B43: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of PTHrP-mediated calcium signaling

IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment

Abstract 4713: BET bromodomain inhibition synergizes with PD-1 blockade to facilitate anti-tumor response in Kras-mutant non-small cell lung cancer

Abstract PR04: p120 catenin loss drives pancreatic cancer EMT and metastasis through activation of calcium signaling

Abstract 5503: Interplay between the transcription factors PRRX1 and FOXM1 in pancreatic cancer

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