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Angelo Pugliese
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Journal Articles

Abstract LB-228: Identifying small molecule inhibitors of Fascin 1 using fragment-based drug discovery

Daniel Croft, Stuart Francis, Justin Bower, Andrea Gohlke, Gillian Goodwin, Christopher Gray, Jennifer Konczal, Sophie Macconnachie, Patricia McConnell, Laura McDonald, Heather McKinnon, Mokdad Mezna, Charles Parry, Nikki Paul, Angelo Pugliese, Alexander Schuettelkopf, Laura Machesky, Martin Drysdale
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-228.
https://doi.org/10.1158/1538-7445.AM2017-LB-228
Published: 01 July 2017
View article titled, Abstract LB-228: Identifying small molecule inhibitors of Fascin 1 using fragment-based drug discovery
Journal Articles

Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity

Dong Joon Kim, Eunmiri Roh, Mee-Hyun Lee, Naomi Oi, Do Young Lim, Myoung Ok Kim, Yong-Yeon Cho, Angelo Pugliese, Jung-Hyun Shim, Hanyong Chen, Eun Jin Cho, Jong-Eun Kim, Sun Chul Kang, Souren Paul, Hee Eun Kang, Ji Won Jung, Sung-Young Lee, Sung-Hyun Kim, Kanamata Reddy, Young Il Yeom, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2016) 76 (5): 1146–1157.
https://doi.org/10.1158/0008-5472.CAN-15-0442
Published: 29 February 2016
View article titled, Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
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Includes: Supplementary data
Journal Articles

Abstract 2884: Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A4 hydrolase

Yeon-Yong Cho, Naomi Oi, Chul-Ho Jeong, Janos Nadas, Angelo Pugliese, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2884.
https://doi.org/10.1158/1538-7445.AM2011-2884
Published: 15 April 2011
View article titled, Abstract 2884: Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A4 hydrolase
Journal Articles

Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A4 Hydrolase

Naomi Oi, Chul-Ho Jeong, Janos Nadas, Yong-Yeon Cho, Angelo Pugliese, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9755–9764.
https://doi.org/10.1158/0008-5472.CAN-10-2858
Published: 06 December 2010
View article titled, Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A<sub>4</sub> Hydrolase
Open the PDF for Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A<sub>4</sub> Hydrolase in another window
Includes: Supplementary data
Journal Articles

Abstract 1227: Inhibition of the RSK2-ATF1 signaling axis by eriodictyol suppresses neoplastic cell transformation

Kangdong Liu, Yong-Yeon Cho, Ke Yao, Angelo Pugliese, Duo Zheng, Jishai Zhang, Zhiwei He, Margarita Malakhova, Wei-Ya Ma, Ann Bode, Ziming Dong, Zigang Dong
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1227.
https://doi.org/10.1158/1538-7445.AM10-1227
Published: 15 April 2010
View article titled, Abstract 1227: Inhibition of the RSK2-ATF1 signaling axis by eriodictyol suppresses neoplastic cell transformation
Journal Articles

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase

Chul-Ho Jeong, Ann M. Bode, Angelo Pugliese, Yong-Yeon Cho, Hong-Gyum Kim, Jung-Hyun Shim, Young-Jin Jeon, Honglin Li, Hualiang Jiang, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (13): 5584–5591.
https://doi.org/10.1158/0008-5472.CAN-09-0491
Published: 01 July 2009
View article titled, [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase
Open the PDF for [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase in another window
Includes: Supplementary data
Journal Articles

A Regulatory Mechanism for RSK2 NH2-Terminal Kinase Activity

Yong-Yeon Cho, Ke Yao, Angelo Pugliese, Margarita L. Malakhova, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4398–4406.
https://doi.org/10.1158/0008-5472.CAN-08-4959
Published: 15 May 2009
View article titled, A Regulatory Mechanism for RSK2 NH<sub>2</sub>-Terminal Kinase Activity
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Includes: Supplementary data
Journal Articles

Abstract #4098: A regulatory mechanism of RSK2 N-terminal kinase activity

Ke Yao, Yong-Yeon Cho, Angelo Pugliese, Margarita Malakhova, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4098.
Published: 01 May 2009
View article titled, Abstract #4098: A regulatory mechanism of RSK2 N-terminal kinase activity
Journal Articles

Abstract #2461: Modeling of the interaction between EGCG and two separate kinase domains of RSK2

Angelo Pugliese, Jung-Hyun Shim, Margarita Malakhova, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2461.
Published: 01 May 2009
View article titled, Abstract #2461: Modeling of the interaction between EGCG and two separate kinase domains of RSK2
Journal Articles

Abstract #4400: Cdk3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation

Yong-Yeon Cho, Faqing Tang, Ke Yao, Chengrong Lu, Feng Zhu, Duo Zheng, Angelo Pugliese, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4400.
Published: 01 May 2009
View article titled, Abstract #4400: Cdk3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation
Journal Articles

Cyclin-Dependent Kinase-3–Mediated c-Jun Phosphorylation at Ser63 and Ser73 Enhances Cell Transformation

Yong-Yeon Cho, Faqing Tang, Ke Yao, Chengrong Lu, Feng Zhu, Duo Zheng, Angelo Pugliese, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (1): 272–281.
https://doi.org/10.1158/0008-5472.CAN-08-3125
Published: 31 December 2008
View article titled, Cyclin-Dependent Kinase-3–Mediated c-Jun Phosphorylation at Ser63 and Ser73 Enhances Cell Transformation
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Includes: Supplementary data
Journal Articles

EGCG suppresses CD3-mediated T-cell-induced pathways in leukemia cells via Zap-70 inhibition

Jung-Hyun Shim, Hong Seok Choi, Angelo Pugliese, Bu Young Choi, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2344.
Published: 01 May 2008
View article titled, EGCG suppresses CD3-mediated T-cell-induced pathways in leukemia cells via Zap-70 inhibition
Journal Articles

Raf and MEK Protein Kinases Are Direct Molecular Targets for the Chemopreventive Effect of Quercetin, a Major Flavonol in Red Wine

Ki Won Lee, Nam Joo Kang, Yong-Seok Heo, Evgeny A. Rogozin, Angelo Pugliese, Mun Kyung Hwang, G. Tim Bowden, Ann M. Bode, Hyong Joo Lee, Zigang Dong
Journal: Cancer Research
Cancer Res (2008) 68 (3): 946–955.
https://doi.org/10.1158/0008-5472.CAN-07-3140
Published: 01 February 2008
View article titled, Raf and MEK Protein Kinases Are Direct Molecular Targets for the Chemopreventive Effect of Quercetin, a Major Flavonol in Red Wine
Open the PDF for Raf and MEK Protein Kinases Are Direct Molecular Targets for the Chemopreventive Effect of Quercetin, a Major Flavonol in Red Wine in another window