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Anette Duensing
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Journal Articles

Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors

Sergei Boichuk, Derek J. Lee, Keith R. Mehalek, Kathleen R. Makielski, Agnieszka Wozniak, Danushka S. Seneviratne, Nina Korzeniewski, Rolando Cuevas, Joshua A. Parry, Matthew F. Brown, James Zewe, Takahiro Taguchi, Shin-Fan Kuan, Patrick Schöffski, Maria Debiec-Rychter, Anette Duensing
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (4): 1200–1213.
https://doi.org/10.1158/0008-5472.CAN-13-1955
Published: 16 February 2014
View articletitled, Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors
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Includes: Supplementary data
Journal Articles

The DREAM Complex Mediates GIST Cell Quiescence and Is a Novel Therapeutic Target to Enhance Imatinib-Induced Apoptosis

Sergei Boichuk, Joshua A. Parry, Kathleen R. Makielski, Larisa Litovchick, Julianne L. Baron, James P. Zewe, Agnieszka Wozniak, Keith R. Mehalek, Nina Korzeniewski, Danushka S. Seneviratne, Patrick Schöffski, Maria Debiec-Rychter, James A. DeCaprio, Anette Duensing
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (16): 5120–5129.
https://doi.org/10.1158/0008-5472.CAN-13-0579
Published: 13 August 2013
View articletitled, The DREAM Complex Mediates GIST Cell Quiescence and Is a Novel Therapeutic Target to Enhance Imatinib-Induced Apoptosis
Open the PDF for The DREAM Complex Mediates GIST Cell Quiescence and Is a Novel Therapeutic Target to Enhance Imatinib-Induced Apoptosis in another window
Includes: Supplementary data
Journal Articles

Abstract 5354: HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of PLK4, a master regulator of centriole biogenesis

Nina Korzeniewski, Anette Duensing, Stefan Duensing
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5354.
https://doi.org/10.1158/1538-7445.AM10-5354
Published: 15 April 2010
View articletitled, Abstract 5354: HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of PLK4, a master regulator of centriole biogenesis
Journal Articles

Abstract 2974: Cep57 is a novel regulator of centriole overduplication in tumor cells

Rolando A. Cuevas, Anette Duensing, Stefan Duensing
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2974.
https://doi.org/10.1158/1538-7445.AM10-2974
Published: 15 April 2010
View articletitled, Abstract 2974: Cep57 is a novel regulator of centriole overduplication in tumor cells
Journal Articles

Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells

Sebastian Bauer, Joshua A. Parry, Thomas Mühlenberg, Matthew F. Brown, Danushka Seneviratne, Payel Chatterjee, Anna Chin, Brian P. Rubin, Shih-Fan Kuan, Jonathan A. Fletcher, Stefan Duensing, Anette Duensing
Journal: Cancer Research
Cancer Res (2010) 70 (1): 150–159.
https://doi.org/10.1158/0008-5472.CAN-09-1449
Published: 04 January 2010
View articletitled, Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells
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Includes: Supplementary data
Journal Articles

Human Papillomavirus 16 E7 Oncoprotein Attenuates DNA Damage Checkpoint Control by Increasing the Proteolytic Turnover of Claspin

Nicole Spardy, Kathryn Covella, Elliot Cha, Elizabeth E. Hoskins, Susanne I. Wells, Anette Duensing, Stefan Duensing
Journal: Cancer Research
Cancer Res (2009) 69 (17): 7022–7029.
https://doi.org/10.1158/0008-5472.CAN-09-0925
Published: 31 August 2009
View articletitled, Human Papillomavirus 16 E7 Oncoprotein Attenuates DNA Damage Checkpoint Control by Increasing the Proteolytic Turnover of Claspin
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Includes: Supplementary data
Journal Articles

Cullin 1 Functions as a Centrosomal Suppressor of Centriole Multiplication by Regulating Polo-like Kinase 4 Protein Levels

Nina Korzeniewski, Leon Zheng, Rolando Cuevas, Joshua Parry, Payel Chatterjee, Brittany Anderton, Anette Duensing, Karl Münger, Stefan Duensing
Journal: Cancer Research
Cancer Res (2009) 69 (16): 6668–6675.
https://doi.org/10.1158/0008-5472.CAN-09-1284
Published: 12 August 2009
View articletitled, Cullin 1 Functions as a Centrosomal Suppressor of Centriole Multiplication by Regulating Polo-like Kinase 4 Protein Levels
Open the PDF for Cullin 1 Functions as a Centrosomal Suppressor of Centriole Multiplication by Regulating Polo-like Kinase 4 Protein Levels in another window
Includes: Supplementary data
Journal Articles

HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere–Associated Promyelocytic Leukemia Bodies

Nicole Spardy, Anette Duensing, Elizabeth E. Hoskins, Susanne I. Wells, Stefan Duensing
Journal: Cancer Research
Cancer Res (2008) 68 (23): 9954–9963.
https://doi.org/10.1158/0008-5472.CAN-08-0224
Published: 01 December 2008
View articletitled, HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere–Associated Promyelocytic Leukemia Bodies
Open the PDF for HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere–Associated Promyelocytic Leukemia Bodies in another window
Journal Articles

Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27Kip1 Signaling Axis

Ying Liu, Sophie A. Perdreau, Payel Chatterjee, Linan Wang, Shih-Fan Kuan, Anette Duensing
Journal: Cancer Research
Cancer Res (2008) 68 (21): 9015–9023.
https://doi.org/10.1158/0008-5472.CAN-08-1935
Published: 30 October 2008
View articletitled, Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27Kip1 Signaling Axis
Open the PDF for Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27Kip1 Signaling Axis in another window
Includes: Supplementary data
Journal Articles

Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate

Ying Liu, Michelle Tseng, Sophie A. Perdreau, Ferdinand Rossi, Cristina Antonescu, Peter Besmer, Jonathan A. Fletcher, Stefan Duensing, Anette Duensing
Journal: Cancer Research
Cancer Res (2007) 67 (6): 2685–2692.
https://doi.org/10.1158/0008-5472.CAN-06-3497
Published: 15 March 2007
View articletitled, Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate
Open the PDF for Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate in another window
Includes: Supplementary data
Journal Articles

The Fanconi Anemia pathway protects cells from human papillomavirus type 16 E7 oncoprotein-induced DNA damage and genomic instability.

Nicole Spardy, Domonique Charles, Ying Liu, Tomomi Nakahara, Paul Lambert, Anette Duensing, Stefan Duensing
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1327.
Published: 15 April 2006
View articletitled, The Fanconi Anemia pathway protects cells from human papillomavirus type 16 E7 oncoprotein-induced DNA damage and genomic instability.
Journal Articles

Cdk2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication

Anette Duensing, Ying Liu, Marcos Malumbres, Mariano Barbacid, Stefan Duensing
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 753–754.
Published: 15 April 2006
View articletitled, Cdk2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication
Journal Articles

Cell cycle re-entry precedes the apoptotic response following transitory activation of the DNA replication checkpoint

Anette Duensing, Ying Liu, Michelle Tseng, Xiaoyi Teng, Stefan Duensing
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 834–835.
Published: 01 May 2005
View articletitled, Cell cycle re-entry precedes the apoptotic response following transitory activation of the DNA replication checkpoint
Journal Articles

Protein Kinase C θ (PKCθ) Expression and Constitutive Activation in Gastrointestinal Stromal Tumors (GISTs)

Anette Duensing, Nora E. Joseph, Fabiola Medeiros, Felicity Smith, Jason L. Hornick, Michael C. Heinrich, Christopher L. Corless, George D. Demetri, Christopher D. M. Fletcher, Jonathan A. Fletcher
Journal: Cancer Research
Cancer Res (2004) 64 (15): 5127–5131.
https://doi.org/10.1158/0008-5472.CAN-04-0559
Published: 02 August 2004
View articletitled, Protein Kinase C θ (PKCθ) Expression and Constitutive Activation in Gastrointestinal Stromal Tumors (GISTs)
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Journal Articles

Dissecting the role of cyclin E in human papillomavirus type 16 E7-induced centrosome duplication errors

Anette Duensing, Yan Geng, Peter Sicinski, Karl Münger, Stefan Duensing
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 600.
Published: 01 April 2004
View articletitled, Dissecting the role of cyclin E in human papillomavirus type 16 E7-induced centrosome duplication errors
Journal Articles

KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors

Brian P. Rubin, Samuel Singer, Connie Tsao, Anette Duensing, Marcia L. Lux, Robert Ruiz, Michele K. Hibbard, Chang-Jie Chen, Sheng Xiao, David A. Tuveson, George D. Demetri, Christopher D. M. Fletcher, Jonathan A. Fletcher
Journal: Cancer Research
Cancer Res (2001) 61 (22): 8118–8121.
Published: 01 November 2001
View articletitled, KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors
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Journal Articles

Human Papillomavirus Type 16 E7 Oncoprotein-induced Abnormal Centrosome Synthesis Is an Early Event in the Evolving Malignant Phenotype

Stefan Duensing, Anette Duensing, Christopher P. Crum, Karl Münger
Journal: Cancer Research
Cancer Res (2001) 61 (6): 2356–2360.
Published: 03 March 2001
View articletitled, Human Papillomavirus Type 16 E7 Oncoprotein-induced Abnormal Centrosome Synthesis Is an Early Event in the Evolving Malignant Phenotype
Open the PDF for Human Papillomavirus Type 16 E7 Oncoprotein-induced Abnormal Centrosome Synthesis Is an Early Event in the Evolving Malignant Phenotype in another window