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Andrew V. Biankin
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Journal Articles

Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

Audrey M Hendley, Sudipta Ashe, Atsushi Urano, Martin Ng, Tuan A Phu, Xianlu Laura Peng, Changfei Luan, Anna-Marie Finger, Gun Ho Jang, Natanya R Kerper, David I Berrios, David Jin, Jonghyun Lee, Irene R Riahi, Oghenekevwe M Gbenedio, Christina Chung, Jeroen P Roose, Jen Jen Yeh, Steven Gallinger, Andrew V Biankin, Grainne M O’Kane, Vasilis Ntranos, David K Chang, David W Dawson, Grace E Kim, Valerie M Weaver, Robert L Raffai, Matthias Hebrok
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A066.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A066
Published: 15 September 2024
View article titled, Abstract A066: nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer
Journal Articles

Abstract PR04: Therapeutic development platform for pancreatic cancer in the UK national health service: Lessons learned and initial results from Precision-Panc

Fieke E.M. Froeling, Juan Valle, Rosie Upstill-Goddard, Paul Grimwood, Paul Westwood, Stephan B. Dreyer, Caroline Kelly, Fraser Duthie, Judith Dixon, Sarah Bradley, T.R. Jeffry Evans, Owen J. Sansom, Andrew V. Biankin, David K. Chang
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): PR04.
https://doi.org/10.1158/1538-7445.PANCA2023-PR04
Published: 16 January 2024
View article titled, Abstract PR04: Therapeutic development platform for pancreatic cancer in the UK national health service: Lessons learned and initial results from Precision-Panc
Journal Articles

Abstract A046: nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma

Audrey M. Hendley, Atsushi Urano, Xianlu L. Peng, Sudipta Ashe, Tuan A. Phu, Martin Ng, Natanya R. Kerper, David I. Berrios, Jonghyun Lee, David Jin, Gun H. Jang, Oghenekevwe M. Gbenedio, Jeroen P. Roose, Jen J. Yeh, Steven Gallinger, Andrew V. Biankin, Vasilis Ntranos, David K. Chang, David W. Dawson, Grace E. Kim, Valerie M. Weaver, Robert L. Raffai, Matthias Hebrok
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A046.
https://doi.org/10.1158/1538-7445.PANCA2023-A046
Published: 16 January 2024
View article titled, Abstract A046: nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma
Journal Articles

Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases

Colin S. Wood, Kathryn A.F. Pennel, Holly Leslie, Assya Legrini, Andrew J. Cameron, Lydia Melissourgou-Syka, Jean A. Quinn, Hester C. van Wyk, Jennifer Hay, Antonia K. Roseweir, Colin Nixon, Campbell S.D. Roxburgh, Donald C. McMillan, Andrew V. Biankin, Owen J. Sansom, Paul G. Horgan, Joanne Edwards, Colin W. Steele, Nigel B. Jamieson
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1329–1344.
https://doi.org/10.1158/0008-5472.CAN-22-2794
Published: 14 April 2023
View article titled, Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
Open the PDF for Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases in another window
Includes: Supplementary data
Journal Articles

Abstract 2112: Reporting recommendations for translational cancer genomic studies

Raffaella Casolino, Philip A. Beer, Nicola Normanno, Zbyslaw Sondka, Andrew V. Biankin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2112.
https://doi.org/10.1158/1538-7445.AM2023-2112
Published: 04 April 2023
View article titled, Abstract 2112: Reporting recommendations for translational cancer genomic studies
Journal Articles

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Gwo Yaw Ho, Elizabeth L. Kyran, Justin Bedo, Matthew J. Wakefield, Darren P. Ennis, Hasan B. Mirza, Cassandra J. Vandenberg, Elizabeth Lieschke, Andrew Farrell, Anthony Hadla, Ratana Lim, Genevieve Dall, James E. Vince, Ngee Kiat Chua, Olga Kondrashova, Rosanna Upstill-Goddard, Ulla-Maja Bailey, Suzanne Dowson, Patricia Roxburgh, Rosalind M. Glasspool, Gareth Bryson, Andrew V. Biankin, for the Scottish Genomes Partnership, Susanna L. Cooke, Gayanie Ratnayake, Orla McNally, Nadia Traficante, for the Australian Ovarian Cancer Study12,13, Anna DeFazio, S. John Weroha, David D. Bowtell, Iain A. McNeish, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4457–4473.
https://doi.org/10.1158/0008-5472.CAN-21-4012
Published: 02 December 2022
View article titled, Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
Open the PDF for Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin in another window
Includes: Supplementary data
Journal Articles

Abstract C085: Spatial arrangements of immune cells of the pancreatic ductal adenocarcinoma tumor microenvironment correlated with outcomes in the phase 3 APACT trial

David J. Reiss, Andrew Browne, Brian Fox, Alexander V. Ratushnyy, Maria Wang, Andrew V. Biankin, Thomas Lila
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C085.
https://doi.org/10.1158/1538-7445.PANCA22-C085
Published: 15 November 2022
View article titled, Abstract C085: Spatial arrangements of immune cells of the pancreatic ductal adenocarcinoma tumor microenvironment correlated with outcomes in the phase 3 APACT trial
Journal Articles

Abstract C051: Ceramide signaling regulates PDA aggression through exosome reprogramming of the stroma

Audrey M. Hendley, Atsushi Urano, Xianlu L. Peng, Sudipta Ashe, Natanya R. Kerper, Tuan A. Phu, Martin Ng, Simone Giacometti, David I. Berrios, Gun H. Jang, Jen J. Yeh, Steven Gallinger, David K. Chang, Andrew V. Biankin, Valerie M. Weaver, Grace E. Kim, David W. Dawson, Robert L. Raffai, Matthias Hebrok
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C051.
https://doi.org/10.1158/1538-7445.PANCA22-C051
Published: 15 November 2022
View article titled, Abstract C051: Ceramide signaling regulates PDA aggression through exosome reprogramming of the stroma
Journal Articles

Abstract C019: FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer

Marta Canel, Aleksandra Slawinska, David W. Lonergan, Ashwin A. Kallor, Rosie Upstill-Goddard, Catherine Davidson, Alex von Kriegsheim, Andrew V. Biankin, Adam Bryron, Javier Alfaro, Alan Serrels
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C019.
https://doi.org/10.1158/1538-7445.PANCA22-C019
Published: 15 November 2022
View article titled, Abstract C019: FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer
Journal Articles

Abstract 1176: Leveraging the GENIE dataset to distinguish somatic cancer drivers from passenger events in routine oncology practice

Philip A. Beer, Susanna L. Cooke, Xuan Shirley Li, Andrew V. Biankin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1176.
https://doi.org/10.1158/1538-7445.AM2022-1176
Published: 15 June 2022
View article titled, Abstract 1176: Leveraging the GENIE dataset to distinguish somatic cancer drivers from passenger events in routine oncology practice
Journal Articles

Abstract IA-12: Precision oncology for pancreatic cancer

Andrew V. Biankin
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): IA-12.
https://doi.org/10.1158/1538-7445.PANCA20-IA-12
Published: 13 November 2020
View article titled, Abstract IA-12: Precision oncology for pancreatic cancer
Journal Articles

Abstract PO-023: Targeting a novel rewired pathway of nucleotide metabolism that drives chemoresistance in the most lethal molecular subtype of pancreatic cancer

Chun-Hao Pan, Yuka Otsuka, BanuPriya Sridharan, Melissa Woo, Cindy V. Leiton, Sruthi Babu, Mariana Torrente Gonçalves, Ryan R. Kawalerski, Ji Dong K. Bai, Richard A. Moffitt, Jiang Zhao, David K. Chang, Andrew V. Biankin, Tim Duong, Pankaj K. Singh, Louis Scampavia, Timothy Spicer, Kenneth R. Shroyer, Luisa F. Escobar-Hoyos
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): PO-023.
https://doi.org/10.1158/1538-7445.PANCA20-PO-023
Published: 13 November 2020
View article titled, Abstract PO-023: Targeting a novel rewired pathway of nucleotide metabolism that drives chemoresistance in the most lethal molecular subtype of pancreatic cancer
Journal Articles

Abstract 815: Precision medicine for pancreatic cancer in national health care system: The initial Precision Panc experience

David K. Chang, Susie Cooke, Stephan B. Dreyer, Jon Stobo, Fraser Duthie, Nigel Jamieson, Judith Dixon, Christine Wilshire, Nicola Williams, Colin J. McKay, Juan W. Valle, Andrew V. Biankin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 815.
https://doi.org/10.1158/1538-7445.AM2020-815
Published: 15 August 2020
View article titled, Abstract 815: Precision medicine for pancreatic cancer in national health care system: The initial Precision Panc experience
Journal Articles

Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression

Audrey M. Hendley, Atsushi Urano, Natanya R. Kerper, Phat Duong, Peter Bailey, David K. Chang, Andrew V. Biankin, David W. Dawson, Grace Kim, Robert L. Raffai, Matthias Hebrok
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C20.
https://doi.org/10.1158/1538-7445.PANCA19-C20
Published: 13 December 2019
View article titled, Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression
Journal Articles

Prolactin Promotes Fibrosis and Pancreatic Cancer Progression

Manuj Tandon, Gina M. Coudriet, Angela Criscimanna, Mairobys Socorro, Mouhanned Eliliwi, Aatur D. Singhi, Zobeida Cruz-Monserrate, Peter Bailey, Michael T. Lotze, Herbert Zeh, Jing Hu, Vincent Goffin, George K. Gittes, Andrew V. Biankin, Farzad Esni
Journal: Cancer Research
Cancer Res (2019) 79 (20): 5316–5327.
https://doi.org/10.1158/0008-5472.CAN-18-3064
Published: 15 October 2019
View article titled, Prolactin Promotes Fibrosis and Pancreatic Cancer Progression
Open the PDF for Prolactin Promotes Fibrosis and Pancreatic Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 2727: The premalignant state captured in the landscape of somatic mutations can reveal the cancer cell-of-origin

Kirsten Kubler, Rosa Karlic, Nicholas J. Haradhvala, Kyungsik Ha, Jaegil Kim, Maja Kuzman, Wei Jiao, Sitanshu Gakkhar, Kent W. Mouw, Lior Z. Braunstein, Olivier Elemento, Andrew V. Biankin, Ilse Rooman, Mendy Miller, Christopher D. Nogiec, Edward Curry, Mari Mino-Kenudson, Leif W. Ellisen, Robert Brown, Alexander Gusev, Cristian Tomasetti, Hong-Gee Kim, Hwajin Lee, Kristian Vlahovicek, Charles Sawyers, Katherine A. Hoadley, Edwin Cuppen, Amnon Koren, Peter F. Arndt, David N. Louis, Lincoln Stein, William D. Foulkes, Paz Polak, Gad Getz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2727.
https://doi.org/10.1158/1538-7445.AM2019-2727
Published: 01 July 2019
View article titled, Abstract 2727: The premalignant state captured in the landscape of somatic mutations can reveal the cancer cell-of-origin
Journal Articles

Abstract 985: The EurOPDX EDIReX project: Towards a European research infrastructure on patient-derived cancer models

Enzo Medico, Mohamed Bentires-Alj, Andrew V. Biankin, Alejandra Bruna, Annette T. Byrne, Carlos Caldas, Robert B. Clarke, Georges Coukos, Olivier Elemento, Manuel Hidalgo, Giorgio Inghirami, Steven de Jong, Jos Jonkers, Ales Krenek, Eleonora Leucci, Gunhild Mari Maelandsmo, Michaela Th. Mayrhofer, Terrence F. Meehan, Simone P. Niclou, Pier Giuseppe Pelicci, Alejandro Piris-Gimenez, Leo Price, Sergio Roman-Roman, Livio Trusolino, Luca Vezzadini, Alberto Villanueva, Emilie Vinolo, on behalf of the EurOPDX Consortium
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 985.
https://doi.org/10.1158/1538-7445.AM2018-985
Published: 01 July 2018
View article titled, Abstract 985: The EurOPDX EDIReX project: Towards a European research infrastructure on patient-derived cancer models
Journal Articles

Abstract A27: Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

Michael E. Feigin, Tyler Garvin, Peter Bailey, Nicola Waddell, David K. Chang, Shimin Shuai, Steven Gallinger, John D. McPherson, Sean M. Grimmond, Ekta Khurana, Lincoln D. Stein, Andrew V. Biankin, Michael C. Schatz, David A. Tuveson
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A27.
https://doi.org/10.1158/1538-7445.PANCA16-A27
Published: 14 December 2016
View article titled, Abstract A27: Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma
Journal Articles

Abstract LB-73: SOX9 regulates EGFR/ERBB signaling in pancreatic cancer

Andreia V. Pinho, Adrien Grimont, Mark J. Cowley, Cecile Augereau, Amanda Mawson, Marc Giry-Laterriere, Geraldine Van den Steen, Nicola Waddell, Marina Pajic, Christine Sempoux, Australian Pancreatic Cancer Genome Initiative, Jianmin Wu, Sean M. Grimmond, Andrew V. Biankin, Frederic P. Lemaigre, Patrick Jacquemin, Ilse Rooman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-73.
https://doi.org/10.1158/1538-7445.AM2014-LB-73
Published: 01 October 2014
View article titled, Abstract LB-73: SOX9 regulates EGFR/ERBB signaling in pancreatic cancer
Journal Articles

Abstract 5138: Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1

Jeyran Shahbazi, Christopher J. Scarlett, Murray Norris, Bing Liu, Michelle Haber, Andrew E. Tee, Alice Carrier, Andrew V. Biankin, Wendy B. London, Glenn M. Marshall, Richard Lock, Tao Liu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5138.
https://doi.org/10.1158/1538-7445.AM2014-5138
Published: 01 October 2014
View article titled, Abstract 5138: Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1