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Journal Articles

Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors

Henry Beetham, Billie G.C. Griffith, Olga Murina, Alexander E.P. Loftus, David A. Parry, Carolin Temps, Jayne Culley, Morwenna Muir, Asier Unciti-Broceta, Andrew H. Sims, Adam Byron, Valerie G. Brunton

Cancer Res (2022) 82 (4): 632–647.

https://doi.org/10.1158/0008-5472.CAN-21-0373

Published: 15 February 2022

View article titled, Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors

Includes: Supplementary data

Journal Articles

Abstract P1-18-07: Can some ER+/HER2+ patients be safely spared from treatment with chemotherapy plus herceptin?

Arran K Turnbull, Victoria Webber, Daniel McStay, Laura M Arthur, Carlos Martinez-Perez, James Meehan, Mark Gray, Charlene Kay, Lorna Renshaw, Jane Keys, Robert Clarke, Andrew H Sims, Olga Oikonomidou, J Michael Dixon

Cancer Res (2020) 80 (4_Supplement): P1-18-07.

https://doi.org/10.1158/1538-7445.SABCS19-P1-18-07

Published: 15 February 2020

View article titled, Abstract P1-18-07: Can some ER+/HER2+ patients be safely spared from treatment with chemotherapy plus herceptin?

Journal Articles

Abstract P2-11-06: Assessment of ESR1 genomic aberrations and their role in endocrine therapy resistance in breast cancer

Carlos Martinez-Perez, Charlene Kay, James Meehan, Mark Gray, Rebecca Swan, Lorna Renshaw, Jane Keys, Andrew H Sims, Olga Oikonomidou, J Michael Dixon, Arran K Turnbull

Cancer Res (2020) 80 (4_Supplement): P2-11-06.

https://doi.org/10.1158/1538-7445.SABCS19-P2-11-06

Published: 15 February 2020

View article titled, Abstract P2-11-06: Assessment of ESR1 genomic aberrations and their role in endocrine therapy resistance in breast cancer

Journal Articles

Abstract P6-16-04: IL6ST, a biomarker of endocrine therapy response, has potential in identifying a subgroup of women with ER+ DCIS who are more likely to benefit from adjuvant endocrine therapy

Carlos Martinez-Perez, Charlene Kay, Rebecca Swan, Gregory E Ekatah, Laura M Arthur, James Meehan, Mark Gray, Andrew H Sims, Olga Oikonomidou, Arran K Turnbull, J Michael Dixon

Cancer Res (2020) 80 (4_Supplement): P6-16-04.

https://doi.org/10.1158/1538-7445.SABCS19-P6-16-04

Published: 15 February 2020

View article titled, Abstract P6-16-04: IL6ST, a biomarker of endocrine therapy response, has potential in identifying a subgroup of women with ER+ DCIS who are more likely to benefit from adjuvant endocrine therapy

Journal Articles

Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis

Sana Sarvi, Hitesh Patel, Jun Li, Georgia L. Dodd, Helen Creedon, Morwenna Muir, Jocelyn Ward, John C. Dawson, Martin Lee, Jayne Culley, Donald M. Salter, Andrew H. Sims, Adam Byron, Valerie G. Brunton

Cancer Res (2018) 78 (6): 1484–1496.

https://doi.org/10.1158/0008-5472.CAN-17-1518

Published: 14 March 2018

View article titled, Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis

Includes: Supplementary data

Journal Articles

Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

Marta Canel, Adam Byron, Andrew H. Sims, Jessy Cartier, Hitesh Patel, Margaret C. Frame, Valerie G. Brunton, Bryan Serrels, Alan Serrels

Cancer Res (2017) 77 (19): 5301–5312.

https://doi.org/10.1158/0008-5472.CAN-17-0418

Published: 01 October 2017

View article titled, Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

Includes: Supplementary data

Journal Articles

Abstract 2698: Transcriptional profiling of human TAMs highlights differences in breast and endometrial tumour microenvironments

Matina Fragkogianni, Luca Cassetta, Agnieszka Swierczak, Lisa Wiechmann, Harriet O. Smith, Andrew H. Sims, Hui Zhang, Lisa M. Coussens, J. W. Pollard

Cancer Res (2016) 76 (14_Supplement): 2698.

https://doi.org/10.1158/1538-7445.AM2016-2698

Published: 15 July 2016

View article titled, Abstract 2698: Transcriptional profiling of human TAMs highlights differences in breast and endometrial tumour microenvironments

Journal Articles

Abstract P3-05-01: Development for clinical utility of a validated predictive test of clinical response to aromatase inhibitors

Arran K Turnbull, Laura Arthur, Victoria Webber, Jeremy Thomas, Charlotte Heerlyn, Phoebe Thornton, Anita Dunbier, Mitch Dowsett, Lorna Renshaw, Andrew H Sims, J Michael Dixon

Cancer Res (2015) 75 (9_Supplement): P3-05-01.

https://doi.org/10.1158/1538-7445.SABCS14-P3-05-01

Published: 01 May 2015

View article titled, Abstract P3-05-01: Development for clinical utility of a validated predictive test of clinical response to aromatase inhibitors

Journal Articles

Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance

Susann Busch, Andrew H. Sims, Olle Stål, Mårten Fernö, Göran Landberg

Cancer Res (2015) 75 (7): 1457–1469.

https://doi.org/10.1158/0008-5472.CAN-14-1583

Published: 31 March 2015

View article titled, Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance

Includes: Supplementary data

Journal Articles

Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy

Laura M. Arthur, Arran K. Turnbull, Victoria L. Webber, Alexey A. Larionov, Lorna Renshaw, Charlene Kay, Jeremy S. Thomas, J. Michael Dixon, Andrew H. Sims

Cancer Res (2014) 74 (19): 5371–5376.

https://doi.org/10.1158/0008-5472.CAN-14-0620

Published: 30 September 2014

View article titled, Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy

Includes: Supplementary data

Journal Articles

Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression

Willem-Jan Keune, Andrew H. Sims, David R. Jones, Yvette Bultsma, James T. Lynch, Karin Jirström, Goran Landberg, Nullin Divecha

Cancer Res (2013) 73 (23): 6913–6925.

https://doi.org/10.1158/0008-5472.CAN-13-0424

Published: 01 December 2013

View article titled, Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression

Includes: Supplementary data

Journal Articles

FRMD4A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis

Stephen J. Goldie, Klaas W. Mulder, David Wei-Min Tan, Scott K. Lyons, Andrew H. Sims, Fiona M. Watt

Cancer Res (2012) 72 (13): 3424–3436.

https://doi.org/10.1158/0008-5472.CAN-12-0423

Published: 01 July 2012

View article titled, FRMD4A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis

Includes: Multimedia, Supplementary data

NARROW

Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors

Abstract P1-18-07: Can some ER+/HER2+ patients be safely spared from treatment with chemotherapy plus herceptin?

Abstract P2-11-06: Assessment of ESR1 genomic aberrations and their role in endocrine therapy resistance in breast cancer

Abstract P6-16-04: IL6ST, a biomarker of endocrine therapy response, has potential in identifying a subgroup of women with ER+ DCIS who are more likely to benefit from adjuvant endocrine therapy

Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis

Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

Abstract 2698: Transcriptional profiling of human TAMs highlights differences in breast and endometrial tumour microenvironments

Abstract P3-05-01: Development for clinical utility of a validated predictive test of clinical response to aromatase inhibitors

Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance

Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy

Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression

FRMD4A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis

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