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Andrea Cercek
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Journal Articles

Abstract CT002: Circulating tumor DNA status to direct adjuvant immunotherapy for mismatch repair deficient tumors

Free
Yelena Yuriy Janjigian, Michael B. Foote, Melissa Lumish, Marinela Capanu, Joanne Chou, Julio Garcia-Aguilar, Martin Weiser, Jason Konner, Vivian Strong, Elizabeth Jewell, Jennifer Mueller, Steven Maron, Ping Gu, Rona Yaeger, Sree Chalasani, Andrea Cercek, Jia Li, Maliha Nusrat, Ryan Sugarman, David Jones, Daniela Molena, David Solit, Brian Loomis, Marc Ladanyi, Michael Berger, Luis A. Diaz
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT002.
https://doi.org/10.1158/1538-7445.AM2025-CT002
Published: 22 May 2025
View articletitled, Abstract CT002: Circulating tumor DNA status to direct adjuvant immunotherapy for mismatch repair deficient tumors
Journal Articles

Abstract CT003: Non operative management of mismatch repair deficient tumors

Free
Andrea Cercek, Michael B. Foote, Jinru Shia, Jenna Sinopoli, Benoit Rousseau, Jesse J. Smith, Jill Weiss, Lindsay Temple, Miteshkumar Patel, Callahan Wilde, Steven Maron, Yelena Janjigian, Daniela Molena, Gopa Iyer, Jonathan Coleman, Wassim Abida, Seth Cohen, Vivian Strong, Mithat Gonen, Marc Gollub, Vetri S. Jayaprakasham, Tae-Hyung Kim, Julio Garcia Aguilar, Martin Weiser, Luis A. Diaz
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT003.
https://doi.org/10.1158/1538-7445.AM2025-CT003
Published: 22 May 2025
View articletitled, Abstract CT003: Non operative management of mismatch repair deficient tumors
Journal Articles

Abstract 3391: Clonality and allelic imbalance of driver genes in a large retrospective cohort of colorectal cancer patients

Free
Henry Walch, Paolo Manca, Jierui Xu, Christopher Fong, Justin Jee, Karl Pichotta, Adam Price, Allison L. Richards, Mark Donoghue, Jinru Shia, Efsevia Vakiani, Neil H. Segal, Andrea Cercek, Nikolaus Schultz, Francisco Sanchez-Vega, Walid K. Chatila, Rona Yaeger
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3391.
https://doi.org/10.1158/1538-7445.AM2025-3391
Published: 21 April 2025
View articletitled, Abstract 3391: Clonality and allelic imbalance of driver genes in a large retrospective cohort of colorectal cancer patients
Journal Articles

Abstract 1152: The landscape of copy number variations following WGD in 5,980 colorectal cancers

Free
Jierui Xu, Henry Walch, Paolo Manca, Maria Perry, Christopher Fong, Justin Jee, Karl Pichotta, Efsevia Vakiani, Neil H. Segal, Adam Price, Allison L. Richards, Chai Bandlamudi, Mark Donoghue, Andrea Cercek, Rona Yaeger, Nikolaus Schultz, Walid K. Chatila
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1152.
https://doi.org/10.1158/1538-7445.AM2025-1152
Published: 21 April 2025
View articletitled, Abstract 1152: The landscape of copy number variations following WGD in 5,980 colorectal cancers
Journal Articles

Abstract 2150: Pre-targeted radioimmunotherapy using self-assembling dis-assembling (SADA) bispecific antibodies for the treatment of appendiceal carcinoma

Free
Nicole Aguirre, Michelle Kim, Hong-Fen Guo, Karina Leung, Sebastian E. Carrasco, Irene Cheung, Michael B. Foote, Andrea Cercek, Sarah M. Cheal, Darren R. Veach, Steven M. Larson, Georgios Karagkounis, Garrett Nash, Nai-Kong Cheung
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2150.
https://doi.org/10.1158/1538-7445.AM2025-2150
Published: 21 April 2025
View articletitled, Abstract 2150: Pre-targeted radioimmunotherapy using self-assembling dis-assembling (SADA) bispecific antibodies for the treatment of appendiceal carcinoma
Journal Articles

Abstract 2856: Pks+ E. coli trigger intestinal stem cell plasticity and early onset colorectal cancer

Free
Stefanie Gerstberger, Melissa Lumish, Saskia Hartner, Farheen Shah, Seongmin Choi, Krystal Lum, Christopher Cowley, Anisha Luthra, Qingwen Jiang, Hyung Jun Woo, Ahmed Mahmoud, Henry Walch, Asha Saxena, Tavis J. Reed, Andrea Cercek, Rona Yaeger, Ileana Cristea, Andrew McPherson, Francisco Sanchez-Vega, Karuna Ganesh
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2856.
https://doi.org/10.1158/1538-7445.AM2025-2856
Published: 21 April 2025
View articletitled, Abstract 2856: Pks+ E. coli trigger intestinal stem cell plasticity and early onset colorectal cancer
Journal Articles

Abstract 2805: Shotgun sequencing of serial fecal microbiome samples in patients with colorectal cancer reveals distinct bacterial species and metabolic pathways associated with tumor sidedness and age at diagnosis

Free
Melissa Lumish, Nicholas Waters, Joshua Leinwand, Asha Saxena, Anqi Dai, Teng Fei, Maggie Fox, Andre Chavez, Jonathan Bermeo, Dorina Ismailgeci, Elizabeth Benitez, Christopher Cowley, Julio Garcia-Aguilar, Martin Weiser, Andrea Cercek, Luis A. Diaz, Marcel van den Brink, Jonathan Peled, Karuna Ganesh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2805.
https://doi.org/10.1158/1538-7445.AM2024-2805
Published: 22 March 2024
View articletitled, Abstract 2805: Shotgun sequencing of serial fecal microbiome samples in patients with colorectal cancer reveals distinct bacterial species and metabolic pathways associated with tumor sidedness and age at diagnosis
Journal Articles

Abstract 2796: Colibactin mutation signatures are associated with younger age of onset in colorectal cancer

Free
Stefanie Gerstberger, Melissa Lumish, Saskia Hartner, Farheen Shah, Seongmin Choi, Anisha Luthra, Qingwen Jiang, Hyung Jun Woo, Ahmed Mahmoud, Henry Walch, Simran Asawa, Mark Donoghue, Andrea Cercek, Rona Yaeger, Andrew McPherson, Francisco Sanchez-Vega, Karuna Ganesh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2796.
https://doi.org/10.1158/1538-7445.AM2024-2796
Published: 22 March 2024
View articletitled, Abstract 2796: Colibactin mutation signatures are associated with younger age of onset in colorectal cancer
Journal Articles

Abstract 1177: Genomic characteristics and clinical outcomes of early onset colorectal cancer (EOCRC): Findings from AACR Project GENIE Biopharma Collaborative registry

Free
Enrique Sanz Garcia, Eric Chen, Marios Giannakis, Gregory J. Riely, Jeremy L. Warner, Michele L. LeNoue-Newton, Jessica Weiss, Katrina Hueniken, Kenneth L. Kehl, Deborah Schrag, Andrea Cercek, Kimmie Ng, AACR GENIE BPC Core Team
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1177.
https://doi.org/10.1158/1538-7445.AM2023-1177
Published: 04 April 2023
View articletitled, Abstract 1177: Genomic characteristics and clinical outcomes of early onset colorectal cancer (EOCRC): Findings from AACR Project GENIE Biopharma Collaborative registry
Journal Articles

Abstract 3474: Molecular subtypes characterize appendiceal adenocarcinoma genomic evolution and disease behavior

Free
Michael B. Foote, Henry Walch, Walid Chatila, Efsevia Vakiani, Chris Chandler, Felix Steinrucke, Garrett Nash, Zsofia Stadler, Sebastian Chung, Yelena Kemel, Anna Maio, Margaret Sheehan, Nikolaus Shultz, Luis A. Diaz, Andrea Cercek
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3474.
https://doi.org/10.1158/1538-7445.AM2022-3474
Published: 15 June 2022
View articletitled, Abstract 3474: Molecular subtypes characterize appendiceal adenocarcinoma genomic evolution and disease behavior
Journal Articles

Abstract CT021: PD-1 blockade in solid tumors with defects in polymerase epsilon

Free
Benoît Rousseau, Ivan Bieche, Eric Pasmant, Nadim Hamzaoui, Nicolas Leulliot, Lucas Michon, Aurelien de Reynies, Mike Foote, Julien Masliah-Planchon, Magali Svrcek, Romain Cohen, Victor Simmet, Paule Augereau, David Malka, Antoine Hollebecque, Damien Pouessel, Carlos Gomez-Roca, Rosine Guimbaud, Amandine Bruyas, Marielle Guillet, Muriel Duluc, Sophie Cousin, Christelle de la Fourchardiere, Frederic Rolland, Sandrine Hiret, Esma Saada-Bouzid, Olivier Bouche, Thierry Andre, Diane Pannier, Farid El Hajbi, Stephane Oudard, Christophe Tournigand, Jean-Charles Soria, Drew Gerber, Dennis Stephens, Michelle Lamandola-Essel, Steven B Maron, Bill Diplas, Guillem Argiles, Asha Krishnan, Neil Segal, Andrea Cercek, Nathalie Hoog-Labouret, Frederic Legrand, Clotide Simon, Assia Lamrani-Ghaouti, Luis A. Diaz, Pierre Saintigny, Sylvie Chevret, Aurelien Marabelle
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT021.
https://doi.org/10.1158/1538-7445.AM2022-CT021
Published: 15 June 2022
View articletitled, Abstract CT021: PD-1 blockade in solid tumors with defects in polymerase epsilon
Journal Articles

Abstract 611: Colibactin mutation signatures are associated with a distinct colorectal cancer clinicopathologic phenotype

Free
Melissa A. Lumish, Anisha Luthra, Simran Asawa, Francesco Cambuli, Mark Donoghue, Hyung Jun Woo, Andrea Cercek, Rona Yaeger, Jinru Shia, Francisco Sanchez-Vega, Karuna Ganesh
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 611.
https://doi.org/10.1158/1538-7445.AM2021-611
Published: 01 July 2021
View articletitled, Abstract 611: Colibactin mutation signatures are associated with a distinct colorectal cancer clinicopathologic phenotype
Journal Articles

Abstract 1391: Self-assembling and disassembling bispecific antibody platform for pretargeted radioimmunotherapy against GPA33 in a xenograft model of colorectal peritoneal carcinomatosis

Free
Sebastian Chung, Mao Wang, Darren Veach, Sarah Cheal, Daniela Burnes Vargas, Shin Hyuk Seo, Blesida Punzalan, Brian Santich, Hong-fen Guo, Hong Xu, Garrett Nash, Andrea Cercek, Christopher Chandler, Steven Larson, Nai-Kong Cheung
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1391.
https://doi.org/10.1158/1538-7445.AM2021-1391
Published: 01 July 2021
View articletitled, Abstract 1391: Self-assembling and disassembling bispecific antibody platform for pretargeted radioimmunotherapy against GPA33 in a xenograft model of colorectal peritoneal carcinomatosis
Journal Articles

Abstract 1122: Germline mutation prevalence in young adults with cancer

Free
Zsofia K. Stadler, Anna Maio, Angelika Padunan, Yelena Kemel, Erin Salo-Mullen, Margaret Sheehan, Kimeisha Belanfanti, Prince R. Tejada, Ozge Birsoy, Diana Mandelker, Liying Zhang, Jesse Galle, Darren Feldman, Laura Boucai, Julia Glade Bender, Anna Piotrowski, Carol Aghajanian, Karen A. Cadoo, Maria I. Carlo, Michael Walsh, Yelena Janjigian, Eileen O'Reilly, Lisa M. DeAngelis, David B. Solit, Barry Taylor, Andrea Cercek, William Tap, Mark E. Robson, Michael F. Berger, Kenneth Offit, Luis A. Diaz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1122.
https://doi.org/10.1158/1538-7445.AM2020-1122
Published: 15 August 2020
View articletitled, Abstract 1122: Germline mutation prevalence in young adults with cancer
Journal Articles

Abstract CT167: First-in-human clinical trial of SC-006, a RNF43 targeted antibody-drug conjugate, as a monotherapy and in combination with budigalimab in patients with advanced colorectal cancer

Free
Katrina S. Pedersen, Amit Mahipal, Andrea Cercek, Susanna Ulahannan, Michael Rossi, Abraham Fong, Daniel Brickman, Johanna Bendell
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT167.
https://doi.org/10.1158/1538-7445.AM2020-CT167
Published: 15 August 2020
View articletitled, Abstract CT167: First-in-human clinical trial of SC-006, a RNF43 targeted antibody-drug conjugate, as a monotherapy and in combination with budigalimab in patients with advanced colorectal cancer
Journal Articles

Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition

Free
Rona Yaeger, Zhan Yao, David M. Hyman, Jaclyn F. Hechtman, Efsevia Vakiani, HuiYong Zhao, Wenjing Su, Lu Wang, Andrew Joelson, Andrea Cercek, Jose Baselga, Elisa de Stanchina, Leonard Saltz, Michael F. Berger, David B. Solit, Neal Rosen
Journal: Cancer Research
Cancer Res (2017) 77 (23): 6513–6523.
https://doi.org/10.1158/0008-5472.CAN-17-0768
Published: 30 November 2017
View articletitled, Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition
Open the PDF for Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 4380: Integrative genomics analysis of metastatic colorectal cancer

Free
Marla Lipsyc, Walid Chatila, Jaclyn F. Hechtman, Francisco Sanchez-Vega, Sumit Middha, Andrea Cercek, Zsofia Stadler, Ritika Kundra, Aijazuddin Syed, David M. Hyman, Ahmet Zehir, Armin Shahrokni, Anna Varghese, Diane Reidy, Neil H. Segal, Efsevia Vakiani, David B. Solit, Marc Ladanyi, Michael F. Berger, Nancy Kemeny, Leonard Saltz, Nikolaus Schultz, Rona Yaeger
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4380.
https://doi.org/10.1158/1538-7445.AM2017-4380
Published: 01 July 2017
View articletitled, Abstract 4380: Integrative genomics analysis of metastatic colorectal cancer