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Andre Oberthuer
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Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View articletitled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Open the PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface in another window
Includes: Supplementary data
Journal Articles

A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers

MoonSun Jung, Amanda J. Russell, Bing Liu, Joshy George, Pei Yan Liu, Tao Liu, Anna DeFazio, David D.L. Bowtell, André Oberthuer, Wendy B. London, Jamie I. Fletcher, Michelle Haber, Murray D. Norris, Michelle J. Henderson
Journal: Cancer Research
Cancer Res (2017) 77 (4): 971–981.
https://doi.org/10.1158/0008-5472.CAN-15-2906
Published: 14 February 2017
View articletitled, A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers
Open the PDF for A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 1611: The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting

Michelle Haber, Jayne Murray, Laura Gamble, Ashleigh Carnegie-Clark, Hannah Webber, Michelle Ruhle, Michelle J. Henderson, Shiloh Middlemass, Daniel Carter, Maria Tsoli, Anahid Ehteda, Sandy Simon, Andre Oberthuer, Matthias Fischer, Katerina Gurova, Catherine Burkhart, Andrei Purmal, Richard B. Lock, David Ziegler, Glenn M. Marshall, Andrei V. Gudkov, Murray D. Norris
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1611.
https://doi.org/10.1158/1538-7445.AM2015-1611
Published: 01 August 2015
View articletitled, Abstract 1611: The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting
Journal Articles

Abstract 789: GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma

Murray D. Norris, Jamie I. Fletcher, Samuele Gherardi, Jayne Murray, Catherine Burkhart, Amanda Russell, Emanuele Valli, Andre Oberthuer, Lesley J. Ashton, Wendy B. London, Glenn M. Marshall, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 789.
https://doi.org/10.1158/1538-7445.AM2012-789
Published: 15 April 2012
View articletitled, Abstract 789: GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma
Journal Articles

N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma

Jamie I. Fletcher, Samuele Gherardi, Jayne Murray, Catherine A. Burkhart, Amanda Russell, Emanuele Valli, Janice Smith, André Oberthuer, Lesley J. Ashton, Wendy B. London, Glenn M. Marshall, Murray D. Norris, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2012) 72 (4): 845–853.
https://doi.org/10.1158/0008-5472.CAN-11-1885
Published: 14 February 2012
View articletitled, N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma
Open the PDF for N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Evaluation of array-based outcome predictors for neuroblastoma

Qing-Rong Chen, Jun Wei, Xinyu Wen, Shahab Asgharzadeh, Robert Seeger, Andre Oberthuer, Frank Berthold, Javed Khan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1721.
Published: 01 May 2008
View articletitled, Evaluation of array-based outcome predictors for neuroblastoma
Journal Articles

Repository of multi-lab array-based neuroblastoma prognosis data

Xinyu Wen, Qingrong Chen, Jun Wei, Shahab Asgharzdeh, Robert Seeger, Andre Oberthuer, Matthias Fischer, Miki Ohira, Akira Nakagawara, Javed Khan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1733.
Published: 01 May 2008
View articletitled, Repository of multi-lab array-based neuroblastoma prognosis data