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Journal Articles

Abstract 3331: Highly sensitive blood-based multi-cancer screening device with tiered specificity based on diagnostic workflow

Yupeng He, Anton Valouev, Liyang Xiong, William W. Young Greenwald, Victoria M. Raymond, Sven Duenwald, AmirAli Talasaz

Cancer Res (2023) 83 (7_Supplement): 3331.

https://doi.org/10.1158/1538-7445.AM2023-3331

Published: 04 April 2023

View article titled, Abstract 3331: Highly sensitive blood-based multi-cancer screening device with tiered specificity based on diagnostic workflow

Journal Articles

Abstract 2141: Development of a highly-sensitive targeted cell-free DNA epigenomic assay for early-stage multi-cancer screening

Anton Valouev, Elena Zotenko, Matthew Snyder, Charbel Eid, Ngan Nguyen, Jun Min, Yupeng He, Ariel Jaimovich, Haley Axelrod, Prashanthi Natarajan, Anna Hartwig, Noam Vardi, Tam Banh, Andrew Kennedy, William Greenleaf, Stefanie Mortimer, Sven Duenwald, Darya Chudova, AmirAli Talasaz

Cancer Res (2022) 82 (12_Supplement): 2141.

https://doi.org/10.1158/1538-7445.AM2022-2141

Published: 15 June 2022

View article titled, Abstract 2141: Development of a highly-sensitive targeted cell-free DNA epigenomic assay for early-stage multi-cancer screening

Journal Articles

Abstract P5-13-29: Analytical and clinical validation of a ctDNA assay for detecting copy number loss and structural rearrangement variants contributing to homologous recombination and repair (HRR) deficiency

Cancer Res (2022) 82 (4_Supplement): P5-13-29.

https://doi.org/10.1158/1538-7445.SABCS21-P5-13-29

Published: 15 February 2022

View article titled, Abstract P5-13-29: Analytical and clinical validation of a ctDNA assay for detecting copy number loss and structural rearrangement variants contributing to homologous recombination and repair (HRR) deficiency

Journal Articles

Abstract 25: Reversion patterns in homologous recombination repair genes in metastatic cancer patients profiled by cell-free DNA

Yu Fu, Jennifer Yen, Alexander Aartyomenko, Sante Gnerre, Caroline Weiport, Elena Helman, Arielle Yablonovitch, Stephen Pettitt, Christopher Llord, Andrew Tutt, Rebecca Nagy, Justin Odegaard, Darya Chudova, AmirAli Talasaz

Cancer Res (2021) 81 (13_Supplement): 25.

https://doi.org/10.1158/1538-7445.AM2021-25

Published: 01 July 2021

View article titled, Abstract 25: Reversion patterns in homologous recombination repair genes in metastatic cancer patients profiled by cell-free DNA

Journal Articles

Abstract 571: Detection of somatic copy number alterations from on-target and off-target sequencing data

Catalin Barbacioru, Han-Yu Chuang, Rebecca Nagy, Darya Chudova, AmirAli Talasaz

Cancer Res (2021) 81 (13_Supplement): 571.

https://doi.org/10.1158/1538-7445.AM2021-571

Published: 01 July 2021

View article titled, Abstract 571: Detection of somatic copy number alterations from on-target and off-target sequencing data

Journal Articles

Abstract 537: NTRK1 fusion detection from clinical cfDNA NGS using a de novo fusion caller

Arielle Yablonovitch, Sante Gnerre, Jennifer Yen, Scott Shell, Elena Helman, Stephen Fairclough, Rebecca J. Nagy, Justin Odegaard, Darya Chudova, AmirAli Talasaz

Cancer Res (2021) 81 (13_Supplement): 537.

https://doi.org/10.1158/1538-7445.AM2021-537

Published: 01 July 2021

View article titled, Abstract 537: NTRK1 fusion detection from clinical cfDNA NGS using a <em>de novo</em> fusion caller

Journal Articles

Abstract 401: Comparison of molecular response calculations for prediction of patient outcome

Allysia J. Mak, Katie J. Quinn, Carin Espenschied, Kyle Chang, Han-Yu Chuang, Elena Helman, Darya Chudova, Justin Odegaard, Becky Nagy, AmirAli Talasaz

Cancer Res (2021) 81 (13_Supplement): 401.

https://doi.org/10.1158/1538-7445.AM2021-401

Published: 01 July 2021

View article titled, Abstract 401: Comparison of molecular response calculations for prediction of patient outcome

Journal Articles

Abstract 2316: Integrated genomic and epigenomic cell-free DNA (cfDNA) analysis for the detection of early-stage colorectal cancer

Oscar Westesson, Haley Axelrod, Jason Dean, Yupeng He, Paul Sample, Elena Zotenko, Ruth McCole, Mohit Goel, Charbel Eid, Jessica Kurata, Yu Kong, Anna Hartwig, Matthew Snyder, Will Greenleaf, Victoria M. Raymond, Darya Chudova, Ariel Jaimovich, AmirAli Talasaz

Cancer Res (2020) 80 (16_Supplement): 2316.

https://doi.org/10.1158/1538-7445.AM2020-2316

Published: 15 August 2020

View article titled, Abstract 2316: Integrated genomic and epigenomic cell-free DNA (cfDNA) analysis for the detection of early-stage colorectal cancer

Journal Articles

Abstract 729: Landscape of homologous recombination repair (HRR) mutations in prostate cancer profiled by ctDNA next-generation sequencing

Jennifer Yen, Sante Gnerre, Catalin Barbacioru, Elena Helman, Ohad Manor, Arielle Yablonovitch, Ravi Vijaya Satya, Leo Liu, Jennifer Saam, Stephen Fairclough, Becky Nagy, Richard Lanman, Darya Chudova, AmirAli Talasaz

Cancer Res (2020) 80 (16_Supplement): 729.

https://doi.org/10.1158/1538-7445.AM2020-729

Published: 15 August 2020

View article titled, Abstract 729: Landscape of homologous recombination repair (HRR) mutations in prostate cancer profiled by ctDNA next-generation sequencing

Journal Articles

Abstract 3404: Landscape and genomic correlates of ctDNA-based tumor mutational burden across six solid tumor types

Katie Quinn, Elena Helman, Tracy Nance, Jennifer Yen, John Latham, Kristin Gleitsman, Ravi Vijaya-Satya, Carlo Artieri, Alex Artyomenko, Marcin Sikora, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 3404.

https://doi.org/10.1158/1538-7445.AM2019-3404

Published: 01 July 2019

View article titled, Abstract 3404: Landscape and genomic correlates of ctDNA-based tumor mutational burden across six solid tumor types

Journal Articles

Abstract 2509: Analysis of clonal hematopoiesis-associated mutations in the cell-free DNA of advanced cancer patients

Jennifer Yen, Katie Quinn, Elena Helman, Andrey Chursov, Tracy Nance, Ariel Jaimovich, Kimberly Banks, Aleksandra Franovic, Kristin Gleitsman, John Latham, Arielle Yablonovitch, Marcin Sikora, Stephen Fairclough, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 2509.

https://doi.org/10.1158/1538-7445.AM2019-2509

Published: 01 July 2019

View article titled, Abstract 2509: Analysis of clonal hematopoiesis-associated mutations in the cell-free DNA of advanced cancer patients

Journal Articles

Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Catalin Barbacioru, Victoria M. Raymond, Marcin Sikora, Elena Helman, Sante Gnerre, Stephen Fairclough, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 435.

https://doi.org/10.1158/1538-7445.AM2019-435

Published: 01 July 2019

View article titled, Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Journal Articles

Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Seung-Tae Kim, Victoria M. Raymond, Joon Oh Park, Elena Zotenko, Young Suk Park, Matthew Schultz, Won Ki Kang, Oscar Westesson, Hee-Cheol Kim, Yupeng He, Justin I. Odegaard, Stefanie A. Mortimer, William J. Greenleaf, Ariel Jaimovich, Jeeyun Lee, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 916.

https://doi.org/10.1158/1538-7445.AM2019-916

Published: 01 July 2019

View article titled, Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Journal Articles

Abstract 1675: Analytical validation of MSI High detection with GuardantOMNI

Jing Zhao, Alexander Artyomenko, Carlo Artieri, John Latham, Stephen R. Fairclough, Catalin Barbacioru, Elena Helman, John Strickler, Darya Chudova, Richard Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 1675.

https://doi.org/10.1158/1538-7445.AM2019-1675

Published: 01 July 2019

View article titled, Abstract 1675: Analytical validation of MSI High detection with GuardantOMNI

Journal Articles

Abstract 3769: Detection of allele specific loss of heterozygosity in 70,000 patients with ctDNA

Jing Zhao, Stephen R. Fairclough, Darya Chudova, Richard Lanman, AmirAli Talasaz, Aaron Hardin

Cancer Res (2019) 79 (13_Supplement): 3769.

https://doi.org/10.1158/1538-7445.AM2019-3769

Published: 01 July 2019

View article titled, Abstract 3769: Detection of allele specific loss of heterozygosity in 70,000 patients with ctDNA

Journal Articles

Abstract 1183: Targeted sequencing of cell-free DNA data enables comprehensive profiling of tumor copy number landscape from blood

Catalin Barbacioru, Eric Collisson, Darya Chudova, Justin Odegaard, Richard Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 1183.

https://doi.org/10.1158/1538-7445.AM2018-1183

Published: 01 July 2018

View article titled, Abstract 1183: Targeted sequencing of cell-free DNA data enables comprehensive profiling of tumor copy number landscape from blood

Journal Articles

Abstract 2190: A method for differentiating clonal driver mutations from subclonal emerging resistance mutations in circulating cell-free DNA

Stephen Fairclough, Oliver Zill, Catalin Barbacioru, Justin Odegaard, Richard B. Lanman, AmirAli Talasaz, Darya Chudova

Cancer Res (2018) 78 (13_Supplement): 2190.

https://doi.org/10.1158/1538-7445.AM2018-2190

Published: 01 July 2018

View article titled, Abstract 2190: A method for differentiating clonal driver mutations from subclonal emerging resistance mutations in circulating cell-free DNA

Journal Articles

Abstract 4272: A novel approach to differentiation of somatic vs. germline variants in liquid biopsies using a betabinomial model

Tracy Nance, Elena Helman, Carlo Artieri, Jennifer Yen, Thomas P. Slavin, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 4272.

https://doi.org/10.1158/1538-7445.AM2018-4272

Published: 01 July 2018

View article titled, Abstract 4272: A novel approach to differentiation of somatic vs. germline variants in liquid biopsies using a betabinomial model

Journal Articles

Abstract 5603: Analytical validation of a comprehensive 500-gene ctDNA panel designed for immuno-oncology and DNA damage research

Elena Helman, Carlo Artieri, James V. Vowles, Jennifer Yen, Tracy Nance, Marcin Sikora, Joshua Gourneau, Mohit Goel, Stefanie Mortimer, Darya Chudova, Justin Odegaard, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 5603.

https://doi.org/10.1158/1538-7445.AM2018-5603

Published: 01 July 2018

View article titled, Abstract 5603: Analytical validation of a comprehensive 500-gene ctDNA panel designed for immuno-oncology and DNA damage research

Journal Articles

Abstract 636: Accounting for processed pseudogene-related artifacts improves specificity of clinical cancer diagnostic sequencing

Carlo G. Artieri, Marcin Sikora, Alex Artyomenko, Elena Helman, Darya Chudova, Richard Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 636.

https://doi.org/10.1158/1538-7445.AM2018-636

Published: 01 July 2018

View article titled, Abstract 636: Accounting for processed pseudogene-related artifacts improves specificity of clinical cancer diagnostic sequencing

NARROW

Abstract 3331: Highly sensitive blood-based multi-cancer screening device with tiered specificity based on diagnostic workflow

Abstract 2141: Development of a highly-sensitive targeted cell-free DNA epigenomic assay for early-stage multi-cancer screening

Abstract P5-13-29: Analytical and clinical validation of a ctDNA assay for detecting copy number loss and structural rearrangement variants contributing to homologous recombination and repair (HRR) deficiency

Abstract 25: Reversion patterns in homologous recombination repair genes in metastatic cancer patients profiled by cell-free DNA

Abstract 571: Detection of somatic copy number alterations from on-target and off-target sequencing data

Abstract 537: NTRK1 fusion detection from clinical cfDNA NGS using a de novo fusion caller

Abstract 401: Comparison of molecular response calculations for prediction of patient outcome

Abstract 2316: Integrated genomic and epigenomic cell-free DNA (cfDNA) analysis for the detection of early-stage colorectal cancer

Abstract 729: Landscape of homologous recombination repair (HRR) mutations in prostate cancer profiled by ctDNA next-generation sequencing

Abstract 3404: Landscape and genomic correlates of ctDNA-based tumor mutational burden across six solid tumor types

Abstract 2509: Analysis of clonal hematopoiesis-associated mutations in the cell-free DNA of advanced cancer patients

Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Abstract 1675: Analytical validation of MSI High detection with GuardantOMNI

Abstract 3769: Detection of allele specific loss of heterozygosity in 70,000 patients with ctDNA

Abstract 1183: Targeted sequencing of cell-free DNA data enables comprehensive profiling of tumor copy number landscape from blood

Abstract 2190: A method for differentiating clonal driver mutations from subclonal emerging resistance mutations in circulating cell-free DNA

Abstract 4272: A novel approach to differentiation of somatic vs. germline variants in liquid biopsies using a betabinomial model

Abstract 5603: Analytical validation of a comprehensive 500-gene ctDNA panel designed for immuno-oncology and DNA damage research

Abstract 636: Accounting for processed pseudogene-related artifacts improves specificity of clinical cancer diagnostic sequencing

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