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Ambra Pozzi
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Journal Articles

Abstract 134: Integrating spatial transcriptomics and second harmonic generation imaging of collagen identifies genes associated with discoidin domain receptor 1 and collagen alignment in colorectal cancer

Free
Maxwell Stuart Hamilton, Harsimran Kaur, Alan J. Simmons, Ken S. Lau, Ambra Pozzi, Robery J. Coffey
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 134.
https://doi.org/10.1158/1538-7445.AM2025-134
Published: 21 April 2025
View articletitled, Abstract 134: Integrating spatial transcriptomics and second harmonic generation imaging of collagen identifies genes associated with discoidin domain receptor 1 and collagen alignment in colorectal cancer
Journal Articles

Abstract A033: Integrating spatial transcriptomics and second harmonic generation imaging to identify targets of supermere-associated Discoidin Domain Receptor 1 involved in collagen alignment

Free
Maxwell S. Hamilton, Oleg Tutanov, Harsimran Kaur, Alan J. Simmons, Clark Massick, Kasey Vickers, Ken S. Lau, Ambra Pozzi, Robert J. Coffey
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): A033.
https://doi.org/10.1158/1538-7445.TUMBODY-A033
Published: 17 November 2024
View articletitled, Abstract A033: Integrating spatial transcriptomics and second harmonic generation imaging to identify targets of supermere-associated Discoidin Domain Receptor 1 involved in collagen alignment
Journal Articles

The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production

Free
Lindsay N. Sausville, Mahesha H. Gangadhariah, Manuel Chiusa, Shaojun Mei, Shouzuo Wei, Roy Zent, James M. Luther, Megan M. Shuey, Jorge H. Capdevila, John R. Falck, F. Peter Guengerich, Scott M. Williams, Ambra Pozzi
Journal: Cancer Research
Cancer Res (2018) 78 (17): 4865–4877.
https://doi.org/10.1158/0008-5472.CAN-17-3977
Published: 04 September 2018
View articletitled, The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production
Open the PDF for The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production in another window
Includes: Supplementary data
Journal Articles

PPARα Activation Can Help Prevent and Treat Non–Small Cell Lung Cancer

Free
Nataliya Skrypnyk, Xiwu Chen, Wen Hu, Yan Su, Stacey Mont, Shilin Yang, Mahesha Gangadhariah, Shouzuo Wei, John R. Falck, Jawahar Lal Jat, Roy Zent, Jorge H. Capdevila, Ambra Pozzi
Journal: Cancer Research
Cancer Res (2014) 74 (2): 621–631.
https://doi.org/10.1158/0008-5472.CAN-13-1928
Published: 16 January 2014
View articletitled, PPARα Activation Can Help Prevent and Treat Non–Small Cell Lung Cancer
Open the PDF for PPARα Activation Can Help Prevent and Treat Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

Free
Shizhen Emily Wang, Bin Xiang, Roy Zent, Vito Quaranta, Ambra Pozzi, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2009) 69 (2): 475–482.
https://doi.org/10.1158/0008-5472.CAN-08-2649
Published: 15 January 2009
View articletitled, Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton
Open the PDF for Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton in another window
Includes: Supplementary data
Journal Articles

Loss of Integrin α1β1 Ameliorates Kras-Induced Lung Cancer

Free
Ines Macias-Perez, Corina Borza, Xiwu Chen, Xuexian Yan, Raquel Ibanez, Glenda Mernaugh, Lynn M. Matrisian, Roy Zent, Ambra Pozzi
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6127–6135.
https://doi.org/10.1158/0008-5472.CAN-08-1395
Published: 01 August 2008
View articletitled, Loss of Integrin α1β1 Ameliorates Kras-Induced Lung Cancer
Open the PDF for Loss of Integrin α1β1 Ameliorates Kras-Induced Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Transforming Growth Factor-β (TGF-β) and TGF-β–Associated Kinase 1 Are Required for R-Ras–Mediated Transformation of Mammary Epithelial Cells

Free
Mete Erdogan, Ambra Pozzi, Neil Bhowmick, Harold L. Moses, Roy Zent
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6224–6231.
https://doi.org/10.1158/0008-5472.CAN-08-0513
Published: 01 August 2008
View articletitled, Transforming Growth Factor-β (TGF-β) and TGF-β–Associated Kinase 1 Are Required for R-Ras–Mediated Transformation of Mammary Epithelial Cells
Open the PDF for Transforming Growth Factor-β (TGF-β) and TGF-β–Associated Kinase 1 Are Required for R-Ras–Mediated Transformation of Mammary Epithelial Cells in another window
Journal Articles

Validating mathematical tumor invasion model simulations using xenograft mouse models of cancer invasion.

Free
Lisa McCawley, Bobby Guillory*, Donna Hicks*, Mary Loveless*, James McIntyre, Xiwu Chen, Jin Chen, Tom Yankeelov, Ambra Pozzi, Lynn Matrisian, Alexander Anderson, Vito Quaranta
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4421.
Published: 01 May 2007
View articletitled, Validating mathematical tumor invasion model simulations using xenograft mouse models of cancer invasion.
Journal Articles

Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation

Free
Nina M. Muñoz, Melissa Upton, Andres Rojas, M. Kay Washington, Li Lin, Anna Chytil, Elif G. Sozmen, Blair B. Madison, Ambra Pozzi, Randall T. Moon, Harold L. Moses, William M. Grady
Journal: Cancer Research
Cancer Res (2006) 66 (20): 9837–9844.
https://doi.org/10.1158/0008-5472.CAN-06-0890
Published: 17 October 2006
View articletitled, Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation
Open the PDF for Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation in another window
Journal Articles

Analysis of Host- and Tumor-Derived Proteinases Using a Custom Dual Species Microarray Reveals a Protective Role for Stromal Matrix Metalloproteinase-12 in Non–Small Cell Lung Cancer

Free
Heath B. Acuff, Mark Sinnamon, Barbara Fingleton, Braden Boone, Shawn E. Levy, Xiwu Chen, Ambra Pozzi, David P. Carbone, Donald R. Schwartz, Kamiar Moin, Bonnie F. Sloane, Lynn M. Matrisian
Journal: Cancer Research
Cancer Res (2006) 66 (16): 7968–7975.
https://doi.org/10.1158/0008-5472.CAN-05-4279
Published: 15 August 2006
View articletitled, Analysis of Host- and Tumor-Derived Proteinases Using a Custom Dual Species Microarray Reveals a Protective Role for Stromal Matrix Metalloproteinase-12 in Non–Small Cell Lung Cancer
Open the PDF for Analysis of Host- and Tumor-Derived Proteinases Using a Custom Dual Species Microarray Reveals a Protective Role for Stromal Matrix Metalloproteinase-12 in Non–Small Cell Lung Cancer in another window
Journal Articles

EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival

Free
P. Charles Lin, Masako Kamiyama, Li Yang, Laura M. Debusk, Richard M. Breyer, Ambra Pozzi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 249–250.
Published: 15 April 2006
View articletitled, EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival
Journal Articles

Role of the MMP/angiostatin axis in the control of lung cancer progression

Free
Xiwu Chen, Barbara Fingleton, Heith Acuff, Lynn Matrisian, Ambra Pozzi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1175–1176.
Published: 01 April 2004
View articletitled, Role of the MMP/angiostatin axis in the control of lung cancer progression