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Alvaro Teijeira
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Journal Articles

Abstract 1178: In vivo, visualization of immune cell dynamics upon the arrival of liver metastatic cells reveals the initiation of initial intravascular immune responses against pioneering tumor cells

Free
Beatrice Pinci, Almudena Manzanal, Carlos Luri-Rey, Maria Lucia Chiclana, David Causapé, Ignacio Melero, Alvaro Teijeira
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1178.
https://doi.org/10.1158/1538-7445.AM2025-1178
Published: 21 April 2025
View articletitled, Abstract 1178: In vivo, visualization of immune cell dynamics upon the arrival of liver metastatic cells reveals the initiation of initial intravascular immune responses against pioneering tumor cells
Journal Articles

Abstract 5000: Low dose ionizing radiation elicits the extrusion of neutrophil extracellular traps

Free
Alvaro Teijeira, Ana Martinez-Riaño, Beatrice Pinci, Almudena Manzanal, Paula Molero, Maria E. Rodriguez- Ruiz, Ignacio Melero
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5000.
https://doi.org/10.1158/1538-7445.AM2024-5000
Published: 22 March 2024
View articletitled, Abstract 5000: Low dose ionizing radiation elicits the extrusion of neutrophil extracellular traps
Journal Articles

Abstract 2915: Intratumoral co-injections of NK cells and neutralizing antibodies against the NKG2A inhibitory pathway achieve efficacious anti-tumor responses in a CD8 T cell and cDC1-dependent manner

Free
Maite Alvarez, Maria C. Ochoa, Carmen Molina, Alvaro Teijeira, Saray Garasa, Sandra Sanchez-Gregorio, Irene Olivera, Javier Glez-Vaz, Asunta Cirella, Gabriel Gomis, Jose Gonzalez-Gomariz, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2915.
https://doi.org/10.1158/1538-7445.AM2023-2915
Published: 04 April 2023
View articletitled, Abstract 2915: Intratumoral co-injections of NK cells and neutralizing antibodies against the NKG2A inhibitory pathway achieve efficacious anti-tumor responses in a CD8 T cell and cDC1-dependent manner
Journal Articles

Abstract 614: CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects

Free
Javier Glez-Vaz, Arantza Azpilikueta, Maria Carmen Ochoa, Irene Olivera, Gabriel Gomis, Asunta Cirella, Carlos Luri-Rey, Maite Álvarez, Sergio Ciordia, Pedro Berraondo, Álvaro Teijeira, Fernando Corrales, Juan M Zapata, Ignacio Melero
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 614.
https://doi.org/10.1158/1538-7445.AM2023-614
Published: 04 April 2023
View articletitled, Abstract 614: CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects
Journal Articles

Abstract 2736: Locoregional modified vaccinia ankara (MVA) encoding a single-chain IL-12 achieves efficacy antitumor immune response in peritoneal carcinomatosis

Free
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, José González-Gomariz, Assunta Cirella, Irene Olivera, Maite Alvarez, Álvaro Teijeira, Cigdem Atay Langbein, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2736.
https://doi.org/10.1158/1538-7445.AM2023-2736
Published: 04 April 2023
View articletitled, Abstract 2736: Locoregional modified vaccinia ankara (MVA) encoding a single-chain IL-12 achieves efficacy antitumor immune response in peritoneal carcinomatosis
Journal Articles

Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy

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Alvaro Teijeira, Saray Garasa, Carlos Luri-Rey, Carlos de Andrea, Maria Gato, Carmen Molina, Tsuneyasu Kaisho, Assunta Cirella, Arantza Azpilikueta, Steffanie K. Wculek, Josune Egea, Irene Olivera, Inmaculada Rodriguez, Ana Rouzaut, Vladislav Verkhusha, Karmele Valencia, David Sancho, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4373–4385.
https://doi.org/10.1158/0008-5472.CAN-22-1046
Published: 02 December 2022
View articletitled, Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy
Open the PDF for Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2887: Three dimensional colon cancer organoids model the response to CEA CD3 T cell engagers

Free
Alvaro Teijeira, Itziar Migueliz, Saray Garasa, Marina Bacac, Christian Klein, Ignacio Melero
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2887.
https://doi.org/10.1158/1538-7445.AM2022-2887
Published: 15 June 2022
View articletitled, Abstract 2887: Three dimensional colon cancer organoids model the response to CEA CD3 T cell engagers
Journal Articles

Abstract 3989: DSTYK inhibition sensitizes lung cancer cells to immunotherapy by collapsing cytoprotective autophagy and destroying mitochondrial wellness

Free
Karmele Valencia, Mirari Echepare, Andrea Pasquier, Alvaro Teijeira, Cristina Bertolo, Cristina Sainz, Graziella Bosco, Roman K. Thomas, Jackeline Agorreta, Jose Maria Lopez-Picazo, Joan Frigola, Ramon Amat, Alfonso Calvo, Enriqueta Felip, Luis M. Montuenga
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3989.
https://doi.org/10.1158/1538-7445.AM2022-3989
Published: 15 June 2022
View articletitled, Abstract 3989: DSTYK inhibition sensitizes lung cancer cells to immunotherapy by collapsing cytoprotective autophagy and destroying mitochondrial wellness
Journal Articles

Abstract 628: Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies

Free
Javier Glez-Vaz, Arantza Azpilikueta, Irene Olivera, Assunta Cirella, Álvaro Teijeira, Carmen Ochoa, Maite Álvarez, Iñaki Eguren, Carlos Luri-Rey, Miguel F. Sanmamed, Ignacio Melero
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 628.
https://doi.org/10.1158/1538-7445.AM2022-628
Published: 15 June 2022
View articletitled, Abstract 628: Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies
Journal Articles

Abstract 3826: A therapeutically actionable pro-tumoral axis of cytokines involving interleukin-8, TNFα and IL-1β

Free
Irene Olivera, Rebeca Sanz-Pamplona, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberria, Assunta Cirella, Saray Garasa, Itziar Migueliz, Iñaki Eguren, Miguel F. Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, Maria C. Ochoa, Carlos E. De Andrea, Pedro Berraondo, Álvaro Teijeira, Ignacio Melero
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3826.
https://doi.org/10.1158/1538-7445.AM2022-3826
Published: 15 June 2022
View articletitled, Abstract 3826: A therapeutically actionable pro-tumoral axis of cytokines involving interleukin-8, TNFα and IL-1β
Journal Articles

Abstract 1691: CD137 (4-1BB) costimulation of CD8 T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation

Free
Itziar Otano, Arantza Azpilikueta, Javier Glez-Vaz, Peter Ellmark, Sara Fritzell, Gabriela Fernandez-Hoyos, Michelle Hase Nelson, Maite Alvarez, María del Carmen Ochoa, Elixabet Bolaños, Doina Cuculescu, Patricia Jauregui, Sandra Sanchez, Iñaki Etxeberría, María E. Rodriguez-Ruiz, Miguel F. Sanmamed, Alvaro Teijeira, Pedro Berraondo, Igancio Melero
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1691.
https://doi.org/10.1158/1538-7445.AM2021-1691
Published: 01 July 2021
View articletitled, Abstract 1691: CD137 (4-1BB) costimulation of CD8 T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Journal Articles

Abstract 1698: Cellular cytotoxicity is a form of immunogenic cell death

Free
Luna Minute, Alvaro Teijeira, Alfonso Rodriguez Sánchez-Paulete, Maria del Carmen Ochoa, Maite Alvarez, Itziar Otano, Iñaki Etxeberria, Elixabet Bolaños, Arantza Azpilikueta, Saray Garasa, Noelia Casares, José Luiz Pérez-Gracia, Maria Esperanza Rodríguez-Ruiz, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1698.
https://doi.org/10.1158/1538-7445.AM2020-1698
Published: 15 August 2020
View articletitled, Abstract 1698: Cellular cytotoxicity is a form of immunogenic cell death
Journal Articles

Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells

Free
Inaki Etxeberria, Elixabet Bolaños, Alvaro Teijeira, Arantza Azpilicueta, Jose Ignacio Quetglas, Alfonso Rodriguez Sanchez-Paulete, Itziar Otano, Uxua Mancheño, Sandra Hervas-Stubbs, Susana Inoges, Saray Garasa, Maite Alvarez, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2331.
https://doi.org/10.1158/1538-7445.AM2019-2331
Published: 01 July 2019
View articletitled, Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells
Journal Articles

Abstract 1474: Repurposing the yellow fever vaccine for intratumoral immunotherapy

Free
M. Angela Aznar, Carmen Molina, Alvaro Teijeira, Arantza Azpilikueta, Saray Garasa, Alfonso R. Sanchez-Paulete, Iñaki Etxeberria, Maite Alvarez, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1474.
https://doi.org/10.1158/1538-7445.AM2019-1474
Published: 01 July 2019
View articletitled, Abstract 1474: Repurposing the yellow fever vaccine for intratumoral immunotherapy
Journal Articles

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus–Derived Vectors Fosters Dendritic Cell–Mediated T-cell Cross-Priming

Free
Alfonso R. Sánchez-Paulete, Álvaro Teijeira, José I. Quetglas, María E. Rodríguez-Ruiz, Álvaro Sánchez-Arráez, Sara Labiano, Iñaki Etxeberria, Arantza Azpilikueta, Elixabet Bolaños, María Cristina Ballesteros-Briones, Noelia Casares, Sergio A. Quezada, Pedro Berraondo, David Sancho, Cristian Smerdou, Ignacio Melero
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6643–6654.
https://doi.org/10.1158/0008-5472.CAN-18-0933
Published: 03 December 2018
View articletitled, Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus–Derived Vectors Fosters Dendritic Cell–Mediated T-cell Cross-Priming
Open the PDF for Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus–Derived Vectors Fosters Dendritic Cell–Mediated T-cell Cross-Priming in another window
Includes: Supplementary data
Journal Articles

Abstract 639: Morphological changes in mitochondria induced by CD137 (4-1BB) co-stimulation on CD8 T cells

Free
Sara Labiano, Álvaro Teijeira, Arantza Azpilikueta, Ángela Aznar, Elixabet Bolaños, Ignacio Melero
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 639.
https://doi.org/10.1158/1538-7445.AM2017-639
Published: 01 July 2017
View articletitled, Abstract 639: Morphological changes in mitochondria induced by CD137 (4-1BB) co-stimulation on CD8 T cells
Journal Articles

Abstract 4015: Exposure of lymphatic endothelial cells to ionizing radiation increases the surface expression levels of integrin ligands

Free
Maria E. Rodriguez-Ruiz, Saray Garasa, Inmaculada Rodriguez, Alba Yanguas, Álvaro Teijeira, Ignacio Melero, Ana Rouzaut
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4015.
https://doi.org/10.1158/1538-7445.AM2016-4015
Published: 15 July 2016
View articletitled, Abstract 4015: Exposure of lymphatic endothelial cells to ionizing radiation increases the surface expression levels of integrin ligands
Journal Articles

Abstract B2: T cell costimulation in cancer immunotherapy with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.

Free
Ivan Martinez-Forero, Arantza Azpilicueta, Elixabet Bolaños-Mateo, Estnislao Nistal-Villan, Asis Palazon, Alvaro Teijeira, Gema Perez-Chacon, Aizea Morales-Kastresana, Oihana Murillo, Maria Jure-Kunkel, Juan Manuel Zapata, Ignacio Melero
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): B2.
https://doi.org/10.1158/1538-7445.TUMIMM2012-B2
Published: 02 April 2014
View articletitled, Abstract B2: T cell costimulation in cancer immunotherapy with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.
Journal Articles

Abstract 3538: The HIF-1α hypoxia response in mouse tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy

Free
Asis Palazon, Ivan Martinez-forero, Alvaro Teijeira, Aizea Morales-Kastresana, Carlos Alfaro, Miguel Fernandez de Sanmamed, Sandra Hervas-Stubbs, Maria Jure-Kunkel, Julian Aragones, Ignacio Melero
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3538.
https://doi.org/10.1158/1538-7445.AM2012-3538
Published: 15 April 2012
View articletitled, Abstract 3538: The HIF-1α hypoxia response in mouse tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Journal Articles

Abstract 4740: Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment ofactivated T lymphocytes

Free
Asis Palazon, Alvaro Teijeira, Iván Martínez-Forero, Sandra Hervás-Stubbs, Carmen Roncal, Juan Dubrot, Aizea Morales-Kastresana, Ana Rouzaut, Maria Jure-Kunkel, Ignacio Melero
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4740.
https://doi.org/10.1158/1538-7445.AM2011-4740
Published: 15 April 2011
View articletitled, Abstract 4740: Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment ofactivated T lymphocytes