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Journal Articles

Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors

Clare F. Malone, Minjee Kim, Gabriela Alexe, Kathleen Engel, Alexandra B. Forman, Amanda Robichaud, Amy Saur Conway, Amy Goodale, Ashleigh Meyer, Delan Khalid, Allen Thayakumar, John M. Hatcher, Nathanael S. Gray, Federica Piccioni, Kimberly Stegmaier
Journal: Cancer Research
Cancer Res (2023) 83 (2): 285–300.
https://doi.org/10.1158/0008-5472.CAN-21-4309
Published: 18 January 2023
View article titled, Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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Includes: Supplementary data
Journal Articles

Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer

Munisha Smalley, Siva Kumar Natarajan, Jayanta Mondal, Douglas Best, David Goldman, Basavaraja Shanthappa, Moriah Pellowe, Chinmayee Dash, Tanmoy Saha, Sachin Khiste, Nithya Ramadurai, Elliot O. Eton, Joshua L. Smalley, Andrew Brown, Allen Thayakumar, Mamunur Rahman, Kazuya Arai, Mohammad Kohandel, Shiladitya Sengupta, Aaron Goldman
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5355–5366.
https://doi.org/10.1158/0008-5472.CAN-19-4036
Published: 02 December 2020
View article titled, Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer
Open the PDF for Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB-346: Case study: Non-uniform response to therapy in multiple metastatic is predicted using CANscriptTM, a live tissue, ex-vivo, platform

Chukwuemeka Ikpeazu, Munisha Smalley, Baraneedharan Ulaganathan, Allen Thayakumar, Laura Majeiko, Jyothsana Ganesh, Basavaraja Shanthappa, Hans Gertje, Mark Lawson, Sara Lapomarda, Aaron Goldman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-346.
https://doi.org/10.1158/1538-7445.AM2018-LB-346
Published: 01 July 2018
View article titled, Abstract LB-346: Case study: Non-uniform response to therapy in multiple metastatic is predicted using CANscript<sup>TM</sup>, a live tissue, <em>ex</em>-<em>vivo</em>, platform
Journal Articles

Abstract 705: Nonuniform T-cell infiltration induced by PD-1 checkpoint blockade, ex vivo, predicts distinct clinical response

Munisha Smalley, Basavaraja Shanthappa, Hans Gertje, Mark Lawson, Baraneedharan Ulaganathan, Allen Thayakumar, D.C. Doval, Anurag Mehta, S. P. Somashekhar, Padhma Radhakrishnan, Pradip Majumder, Aaron J. Goldman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 705.
https://doi.org/10.1158/1538-7445.AM2018-705
Published: 01 July 2018
View article titled, Abstract 705: Nonuniform T-cell infiltration induced by PD-1 checkpoint blockade, <em>ex vivo,</em> predicts distinct clinical response
Journal Articles

Abstract 3397: Intrinsic factors from patient's tumor help neovascularization in an ex vivo platform

Baraneedharan Ulaganathan, Allen Thayakumar B, Manoj Rajappa, Ayyappan Velu, Arun Prasath, Kamal Ameer, Nilesh Brijwani, Padhma Radhakrishnan, Biswanath Majumder, Pradip K. Majumder, Saravanan Thiyagarajan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3397.
https://doi.org/10.1158/1538-7445.AM2016-3397
Published: 15 July 2016
View article titled, Abstract 3397: Intrinsic factors from patient's tumor help neovascularization in an ex vivo platform
Journal Articles

Abstract 1304: Identification of responders for Anti-CTLA4 in refractory colorectal cancers using CANScript™ platform

Biswanath Majumder, Baraneedharan Ulaganathan, Allen Thayakumar, Saravanan Thiyagarajan, Nilesh Brijwani, Biplab Tewari, Basavaraja U. Santhappa, Padhma Radhakrishnan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1304.
https://doi.org/10.1158/1538-7445.AM2015-1304
Published: 01 August 2015
View article titled, Abstract 1304: Identification of responders for Anti-CTLA4 in refractory colorectal cancers using CANScript™ platform
Journal Articles

Abstract 3736: Application of patient tumors-derived tumor ecosystem platform for the development of novel HDAC inhibitor in solid cancers

Mallikarjun Sundaram, Baraneedharan Ulaganathan, Muthu Dhandapani, Allen Thayakumar, Pragnashree Mukhopadhyay, Saravanan Thiyagarajan, Biswanath Majumder, Prasad Shivarudriah, H Jagadheshan, Ganesh Sambasivam, Steve Birnbuam, Padhma Radhakrishnan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3736.
https://doi.org/10.1158/1538-7445.AM2014-3736
Published: 01 October 2014
View article titled, Abstract 3736: Application of patient tumors-derived tumor ecosystem platform for the development of novel HDAC inhibitor in solid cancers
Journal Articles

Abstract 2051: PAT-1102, a novel HDAC inhibitor exhibits potent anti-tumor efficacy in patient-derived refractory solid tumors.

Padhma Radhakrishnan, Muthu Dhandapani, Baraneedharan Ulaganathan, Allen Thayakumar, Saravanan Thiyagarajan, Dency Pinto, D R. Vinod, Biswanath Majumder, Prasad Shivarudriaah, H Jagadheshan, Ganesh Sambasivam, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2051.
https://doi.org/10.1158/1538-7445.AM2013-2051
Published: 15 April 2013
View article titled, Abstract 2051: PAT-1102, a novel HDAC inhibitor exhibits potent anti-tumor efficacy in patient-derived refractory solid tumors.
Journal Articles

Abstract 5072: Human tumor derived Oncoprint® platform predicts molecular mechanism of sensitivity and resistance to Fragmin in pancreatic cancer.

Mallikarjun Sundaram, Saravanan Thiyagarajan, Muthu Dhandapani, Nilesh Brijwani, Arun Prasath, Allen Thayakumar, Ameer Kamal, Padhma Radhakrishnan, Biswanath Majumder, Baraneedharan Ulaganathan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5072.
https://doi.org/10.1158/1538-7445.AM2013-5072
Published: 15 April 2013
View article titled, Abstract 5072: Human tumor derived Oncoprint<sup>®</sup> platform predicts molecular mechanism of sensitivity and resistance to Fragmin in pancreatic cancer.
Journal Articles

Inhibition of Rapamycin-Induced AKT Activation Elicits Differential Antitumor Response in Head and Neck Cancers

Padhma Radhakrishnan, Ulaganathan Baraneedharan, Subhadra Veluchamy, Muthu Dhandapani, Dency D. Pinto, Saravanan Thiyagarajan, Allen Thayakumar, Arun Prasath, Kamal A, Ayyappan Velu, Misti Jain, Nilesh Brijwani, Prasad Narayanan, Vikram D. Kekatpure, Biswanath Majumder, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1118–1127.
https://doi.org/10.1158/0008-5472.CAN-12-2545
Published: 31 January 2013
View article titled, Inhibition of Rapamycin-Induced AKT Activation Elicits Differential Antitumor Response in Head and Neck Cancers
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