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Alfredo Molinolo
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Journal Articles

Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma

Marzia Scortegagna, Yuanning Du, Linda M. Bradley, Kun Wang, Alfredo Molinolo, Eytan Ruppin, Rabi Murad, Ze'ev A. Ronai
Journal: Cancer Research
Cancer Res (2023) 83 (12): 2016–2033.
https://doi.org/10.1158/0008-5472.CAN-23-0258
Published: 15 June 2023
View article titled, Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma
Open the PDF for Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract P5-16-09: Transcriptome modulation by mifepristone treatment in breast cancer patients with higher levels of progesterone receptor A than B

Andres Elia, Martin Abba, Hugo Gass, Caroline A Lamb, Victoria T Fabris, Paula Martinez Vazquez, Javier Burruchaga, Eunice Spengler, Ines Caillet Bois, Alejandra Castets, Silvia Lovisi, Marcos Liguori, Gabriela Pataccini, Maria Florencia Abascal, Virginia Novaro, Alfredo Molinolo, Silvia I Vanzulli, Paola Rojas, Claudia Lanari
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-16-09.
https://doi.org/10.1158/1538-7445.SABCS21-P5-16-09
Published: 15 February 2022
View article titled, Abstract P5-16-09: Transcriptome modulation by mifepristone treatment in breast cancer patients with higher levels of progesterone receptor A than B
Journal Articles

Abstract 1610: Local delivery of anti CTLA4 mediates cDC1 dependent eradication of HNSCC with limited IRAEs in a preclinical model of oral squamous cell carcinoma

Mara Gilardi, Zhiyong Wang, Victoria H. Wu, Miguel Angel Lopez-Ramirez, Fernando Soto-Alvarez, Robert Saddawi-Konefka, Dana Steffen, Marco Proietto, Zbigniew Mikulski, Haruka Miki, Jayanth Shankara Narayanan, Alfredo Molinolo, Joseph Wang, J. Silvio Gutkind
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1610.
https://doi.org/10.1158/1538-7445.AM2021-1610
Published: 01 July 2021
View article titled, Abstract 1610: Local delivery of anti CTLA4 mediates cDC1 dependent eradication of HNSCC with limited IRAEs in a preclinical model of oral squamous cell carcinoma
Journal Articles

Abstract PS11-35: Mipra, a window of opportunity study evaluating mifepristone treatment for postmenopausal breast cancer patients with higher levels of progesterone receptor isoform a than b

Andres Elia, Silvia I Vanzulli, Hugo Gass, Caroline A Lamb, Victoria T Fabris, Paula Martinez Vazquez, Javier Burruchaga, Eunice Spengler, Ines Caillet Bois, Alejandra Castets, Silvia Lovisi, Marcos Liguori, Gabriela Pataccini, M Florencia Abascal, Virginia Novaro, Gabriela Acosta Haab, Alfredo Molinolo, Paola Rojas, Claudia Lanari
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS11-35.
https://doi.org/10.1158/1538-7445.SABCS20-PS11-35
Published: 15 February 2021
View article titled, Abstract PS11-35: Mipra, a window of opportunity study evaluating mifepristone treatment for postmenopausal breast cancer patients with higher levels of progesterone receptor isoform a than b
Journal Articles

Abstract LB-386: Novel multimodal precision immunotherapy by co-targeting the HER3 oncogenic signaling circuitry and PD-1 for head and neck squamous cell carcinoma

Zhiyong Wang, Yusuke Goto, Mara Gilardi, Michael Allevato, Victoria Wu, Robert Saddawi-konefka, Diego Alvarado, Alfredo Molinolo, J. Silvio Gutkind
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-386.
https://doi.org/10.1158/1538-7445.AM2020-LB-386
Published: 15 August 2020
View article titled, Abstract LB-386: Novel multimodal precision immunotherapy by co-targeting the HER3 oncogenic signaling circuitry and PD-1 for head and neck squamous cell carcinoma
Journal Articles

Abstract 1991: Vulnerability of platinum-resistant ovarian cancer to FAK inhibition

Carlos J. Diaz Osterman, Lisa M. Bean, Florian J. Sulzmaier, Kristin N. Taylor, Shulin A. Jiang, Isabelle Tancioni, Kristen Anderson, Christine Jean, Xiao Lei Chen, Elizabeth G. Kleinschmidt, Vihren N. Kolev, David T. Weaver, Jonathan A. Pachter, Denise C. Connolly, Alfredo Molinolo, David D. Schlaepfer
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1991.
https://doi.org/10.1158/1538-7445.AM2018-1991
Published: 01 July 2018
View article titled, Abstract 1991: Vulnerability of platinum-resistant ovarian cancer to FAK inhibition
Journal Articles

Abstract 351: mTOR-ERK co-targeting strategies for head and neck cancer therapy

Zhiyong Wang, Esteban Delgado, Kosuke Yamaguchi, Ramiro Iglesias-Bartolomé, Panomwat Amornphimoltham, Alfredo Molinolo, Qianming Chen, J.Silvio Gutkind
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 351.
https://doi.org/10.1158/1538-7445.AM2017-351
Published: 01 July 2017
View article titled, Abstract 351: mTOR-ERK co-targeting strategies for head and neck cancer therapy
Journal Articles

Abstract LB-243: Targeting the PI3K-mTOR signaling with metformin for the prevention of HPV-associated malignancies in HIV- and HIV+ individuals

Dmitriy Madera, Lynn Vitale-Cross, Daniel Martin, Abraham Schneider, Alfredo Molinolo, J. Silvio Gutkind
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-243.
https://doi.org/10.1158/1538-7445.AM2014-LB-243
Published: 01 October 2014
View article titled, Abstract LB-243: Targeting the PI3K-mTOR signaling with metformin for the prevention of HPV-associated malignancies in HIV- and HIV+ individuals
Journal Articles

Abstract 4952: Germline variation modulates susceptibility to aggressive disease development in a mouse model of prostate tumorigenesis

Kendra A. Williams, Sujata Bupp, Shashank Patel, Jonathan Andreas, Suiyuan Zhang, Alfredo Molinolo, Silvio Gutkind, Nigel Crawford
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4952.
https://doi.org/10.1158/1538-7445.AM2014-4952
Published: 01 October 2014
View article titled, Abstract 4952: Germline variation modulates susceptibility to aggressive disease development in a mouse model of prostate tumorigenesis
Journal Articles

Abstract A60: Germline genetic variation modulates tumor progression and metastasis in mouse prostate neuroendocrine carcinoma

Shashank Patel, Erin Kollins, Katie Bell, Robert Cardiff, Alfredo Molinolo, Nigel Crawford
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): A60.
https://doi.org/10.1158/1538-7445.PRCA2012-A60
Published: 09 May 2013
View article titled, Abstract A60: Germline genetic variation modulates tumor progression and metastasis in mouse prostate neuroendocrine carcinoma
Journal Articles

Abstract 4860: Exon capture analysis of G-protein coupled receptors reveals activating mutations in GRM3 in melanoma

Todd D. Prickett, Xiaomu Wei, Isabel Cardenas-Navia, Jamie Teer, Jimmy C. Lin, Vijay Walia, Jared Gartner, Jiji Jiang, Praveen Cherukuri, Alfredo Molinolo, Michael A. Davies, Katherine Stamke-Hale, Elliott H. Margulies, Steven A. Rosenberg, Yardena Samuels
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4860.
https://doi.org/10.1158/1538-7445.AM2012-4860
Published: 15 April 2012
View article titled, Abstract 4860: Exon capture analysis of G-protein coupled receptors reveals activating mutations in <em>GRM3</em> in melanoma
Journal Articles

Abstract 4970: Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma

Todd D. Prickett, Xiaomu Wei, Cristina G. Viloria, Alfredo Molinolo, Jimmy C. Lin, Pedro Cruz, Steven A. Rosenberg, Michael A. Davies, Jeffrey E. Gershenwald, Carlos López-Otin, Yardena Samuels
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4970.
https://doi.org/10.1158/1538-7445.AM2011-4970
Published: 15 April 2011
View article titled, Abstract 4970: Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma
Journal Articles

Abstract 4324: Loss of TGF-beta receptor I and PTEN promotes HNSCC

Yansong Bian, Bradford Hall, Zhi-Jun Sun, Alfredo Molinolo, Wanjun Chen, Carter Van Waes, Ashok Kulkarni
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4324.
https://doi.org/10.1158/1538-7445.AM2011-4324
Published: 15 April 2011
View article titled, Abstract 4324: Loss of TGF-beta receptor I and PTEN promotes HNSCC
Journal Articles

Abstract 4609: Therapeutic effects of pegylated doxorubicin liposomes in endocrine responsive and unresponsive murine mammary carcinomas

Silvia Vanzulli, Julieta Bolado, Rocío Soldati, Victoria Wargon, Isabel Luthy, Lucas Colombo, Alfredo Molinolo, Claudia Lanari
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4609.
https://doi.org/10.1158/1538-7445.AM10-4609
Published: 15 April 2010
View article titled, Abstract 4609: Therapeutic effects of pegylated doxorubicin liposomes in endocrine responsive and unresponsive murine mammary carcinomas
Journal Articles

Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway

Yansong Bian, Anita Terse, Juan Du, Bradford Hall, Alfredo Molinolo, Pin Zhang, Wanjun Chen, Kathleen C. Flanders, J. Silvio Gutkind, Lalage M. Wakefield, Ashok B. Kulkarni
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5918–5926.
https://doi.org/10.1158/0008-5472.CAN-08-4623
Published: 15 July 2009
View article titled, Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway
Open the PDF for Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway in another window
Includes: Supplementary data
Journal Articles

Rapamycin Prevents Early Onset of Tumorigenesis in an Oral-Specific K-ras and p53 Two-Hit Carcinogenesis Model

Ana R. Raimondi, Alfredo Molinolo, J. Silvio Gutkind
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4159–4166.
https://doi.org/10.1158/0008-5472.CAN-08-4645
Published: 15 May 2009
View article titled, Rapamycin Prevents Early Onset of Tumorigenesis in an Oral-Specific K-<em>ras</em> and <em>p53</em> Two-Hit Carcinogenesis Model
Open the PDF for Rapamycin Prevents Early Onset of Tumorigenesis in an Oral-Specific K-<em>ras</em> and <em>p53</em> Two-Hit Carcinogenesis Model in another window
Includes: Supplementary data
Journal Articles

Abstract #LB-100: Analysis of the Matrix Metalloproteinase Family Reveals MMP-8 is often mutated in Melanoma

Yardena Samuels, Lavanya Palavalli, todd Prickett, john Wunderlich, xiaomu Wei, allison Burrell, patricia Porter-gill, jimmy Lin, alfredo Molinolo, ashani Weeraratna, Lawrrence Brody, Steven Rosenberg, Sean Davis, Chenwei Wang, Julie Cronin, Neena Agrawal, Wendy Westbroek, Shelly Hoogstraten-Miller, Patricia Fetsch, Armando Filie, Michael O'Connell, Phillip Buckhaults, Carolyn Banister, jason howard
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-100.
Published: 01 May 2009
View article titled, Abstract #LB-100: Analysis of the Matrix Metalloproteinase Family Reveals MMP-8 is often mutated in Melanoma
Journal Articles

Gene expression profiles in epithelial and stromal cells from murine mammary tumors with different hormone dependence

Sebastian Giulianelli, Jason Herschkowitz, Vyomesh Patel, Alfredo Molinolo, Silvio Gutkind, Charles Perou, Claudia Lanari
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1698.
Published: 01 May 2008
View article titled, Gene expression profiles in epithelial and stromal cells from murine mammary tumors with different hormone dependence
Journal Articles

FGF receptors (FGFR): stromal-parenchymal interactions and acquisition of hormone independence in the MPA breast cancer model

Juan Cerliani, Caroline Lamb, Maria Bottino, Sebastian Giulianelli, Stephen Hewitt, Alfredo Molinolo, Claudia Lanari
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2786.
Published: 01 May 2007
View article titled, FGF receptors (FGFR): stromal-parenchymal interactions and acquisition of hormone independence in the MPA breast cancer model
Journal Articles

Involvement of PI3K/Akt and Erk1/2 pathways on the regulation of estrogen and progesterone receptor expression in murine mammary tumors.

Victoria Arnoni, Cecilia Bottino, Stephen Hewitt, Alfredo Molinolo, Silvio Gutkind, Claudia Lanari, Virginia Novaro
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1002.
Published: 01 May 2007
View article titled, Involvement of PI3K/Akt and Erk1/2 pathways on the regulation of estrogen and progesterone receptor expression in murine mammary tumors.