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Alexei Martsinkovskiy
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Journal Articles

Abstract LB282: Overcoming chemotherapy resistance in pancreatic cancer: The impact of novel RAS inhibitors and tumor microenvironment modulation

Free
Kevin C. Gulay, Jay Patel, Rithika Medari, Alexei Martsinkovskiy, Timothy Pham, Tatiana Hurtado De Mendoza, Andrew M. Lowy, Hervé Tiriac
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): LB282.
https://doi.org/10.1158/1538-7445.AM2025-LB282
Published: 25 April 2025
View articletitled, Abstract LB282: Overcoming chemotherapy resistance in pancreatic cancer: The impact of novel RAS inhibitors and tumor microenvironment modulation
Journal Articles

Abstract 2582: Silencing MICAL2 expression in pancreatic cancer cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and sensitizes tumors to immune checkpoint blockade therapy

Free
Bharti Garg, Evangeline S. Mose, Edgar Esparaze, Jay Patel, Rithika Medari, Sarah Sass, Alexei Martsinkovskiy, Asmina Courelli, Gisselle Gonzalez, Adam Engler, Parag Katira, Herve Tiriac, Andrew Lowy
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2582.
https://doi.org/10.1158/1538-7445.AM2025-2582
Published: 21 April 2025
View articletitled, Abstract 2582: Silencing MICAL2 expression in pancreatic cancer cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and sensitizes tumors to immune checkpoint blockade therapy
Journal Articles

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Open Access
Bharti Garg, Sohini Khan, Asimina S. Courelli, Ponmathi Panneerpandian, Deepa Sheik Pran Babu, Evangeline S. Mose, Kevin Christian Montecillo Gulay, Shweta Sharma, Divya Sood, Alexander T. Wenzel, Alexei Martsinkovskiy, Nirakar Rajbhandari, Jay Patel, Dawn Jaquish, Edgar Esparza, Katelin Jaque, Neetu Aggarwal, Guillem Lambies, Anthony D’Ippolito, Kathryn Austgen, Brian Johnston, David A. Orlando, Gun Ho Jang, Steven Gallinger, Elliot Goodfellow, Pnina Brodt, Cosimo Commisso, Pablo Tamayo, Jill P. Mesirov, Hervé Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1049–1063.
https://doi.org/10.1158/0008-5472.CAN-24-0744
Published: 14 March 2025
View articletitled, MICAL2 Promotes Pancreatic Cancer Growth and Metastasis
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Includes: Supplementary data
Journal Articles

Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy

Free
Bharti Garg, Evangeline Mose, Edgar Esparaza, Jay Patel, Rithika Medari, Alexei Martsinkovskiy, Carrie Bishop, Gissele Gonzalez, Adam Engler, Parag Katira, Herve Tiriac, Andrew M Lowy
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A052.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A052
Published: 15 September 2024
View articletitled, Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy
Journal Articles

Abstract B055: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Free
Remi Marrocco, Jay Patel, Rithika Medari, Siming Sun, Kevin Gulay, Alexei Martsinkovskiy, Simon Brunel, Eduardo Lucero-Meza, Evangeline Mose, Andrew Lowy, Chris Benedict, Tatiana Hurtado de Mendoza
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): B055.
https://doi.org/10.1158/1538-7445.PANCREATIC24-B055
Published: 15 September 2024
View articletitled, Abstract B055: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy
Journal Articles

Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism

Free
Bharti Garg, EvanGeline Mose, Edgar Esparza, Jay Patel, Sarah Sass, Alexei Martsinkovskiy, Dawn Jacquish, Herve Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A039.
https://doi.org/10.1158/1538-7445.PANCA2023-A039
Published: 16 January 2024
View articletitled, Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism