1-20 of 29
Alexander R.A. Anderson
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy

Open Access
Kit Gallagher, Maximilian A.R. Strobl, Derek S. Park, Fabian C. Spoendlin, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2025) 85 (2): 399.
https://doi.org/10.1158/0008-5472.CAN-24-4438
Published: 15 January 2025
View articletitled, Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy
Open the PDF for Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy in another window
Journal Articles

Abstract C035: Spatially limited stroma-mediated resistance potentiates targeted therapy resistance through an integration of multiple juxtacrine and paracrine mechanisms

Free
Bina Desai, Tatiana Miti, Sandhya Prabhakaran, Daria Miroshnychenko, Menkara Henry, Viktoriya Marusyk, Chandler Gatenbee, Marilyn Bui, Jacob Scott, Philipp M. Altrock, Eric Haura, Alexander R.A. Anderson, David Basanta, Andriy Marusyk
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C035.
https://doi.org/10.1158/1538-7445.TUMBODY-C035
Published: 17 November 2024
View articletitled, Abstract C035: Spatially limited stroma-mediated resistance potentiates targeted therapy resistance through an integration of multiple juxtacrine and paracrine mechanisms
Journal Articles

Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy

Open Access
Kit Gallagher, Maximilian A.R. Strobl, Derek S. Park, Fabian C. Spoendlin, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (11): 1929–1941.
https://doi.org/10.1158/0008-5472.CAN-23-2040
Published: 04 June 2024
View articletitled, Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy
Open the PDF for Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract A011: Modeling the coevolution of native and CAR T-cells in large B cell lymphoma reveals a potential biomarker for response to therapy

Free
Chandler D. Gatenbee, Mark Robertson-Tessi, Maximilian Strobl, Ryan O. Schenck, Bachisio Ziccheddu, Francesco Maura, Frederick Locke, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_2): A011.
https://doi.org/10.1158/1538-7445.CANEVOL23-A011
Published: 01 February 2024
View articletitled, Abstract A011: Modeling the coevolution of native and CAR T-cells in large B cell lymphoma reveals a potential biomarker for response to therapy
Journal Articles

Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics

Open Access
Jill Gallaher, Maximilian Strobl, Jeffrey West, Robert Gatenby, Jingsong Zhang, Mark Robertson-Tessi, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2023) 83 (16): 2775–2789.
https://doi.org/10.1158/0008-5472.CAN-22-2558
Published: 15 August 2023
View articletitled, Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics
Open the PDF for Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract PR008: Immunosuppressive niche engineering at the onset of human colorectal cancer

Free
Chandler D. Gatenbee, Ann-Marie Baker, Ryan O. Schenck, Maximilian Strobl, Jeffrey West, Mark Robertson-Tessi, Trevor A. Graham, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): PR008.
https://doi.org/10.1158/1538-7445.EVODYN22-PR008
Published: 15 May 2022
View articletitled, Abstract PR008: Immunosuppressive niche engineering at the onset of human colorectal cancer
Journal Articles

Abstract B008: Man vs machine: Crowdsourcing vs deep learning of adaptive therapy strategies

Free
Rafael R. Bravo, Brenden K. Peterson, Mark Robertson-Tessi, Daniel M. Faissol, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B008.
https://doi.org/10.1158/1538-7445.EVODYN22-B008
Published: 15 May 2022
View articletitled, Abstract B008: Man vs machine: Crowdsourcing vs deep learning of adaptive therapy strategies
Journal Articles

Abstract A019: Mutation agnostic diagnosis of clonal hematopoiesis of indeterminate potential (CHIP) using fluctuating methylation clocks

Free
Ryan O. Schenck, Niels Asger Jakobsen, Virginia Turati, Darryl Shibata, Paresh Vyas, Simon Leedham, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): A019.
https://doi.org/10.1158/1538-7445.EVODYN22-A019
Published: 15 May 2022
View articletitled, Abstract A019: Mutation agnostic diagnosis of clonal hematopoiesis of indeterminate potential (CHIP) using fluctuating methylation clocks
Journal Articles

Abstract B033: Immunosuppressive niche engineering at the onset of human colorectal cancer

Free
Chandler D. Gatenbee, Ann-Marie Baker, Ryan O. Schenck, Maximilian Strobl, Jeffrey West, Mark Robertson-Tessi, Trevor A. Graham, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B033.
https://doi.org/10.1158/1538-7445.EVODYN22-B033
Published: 15 May 2022
View articletitled, Abstract B033: Immunosuppressive niche engineering at the onset of human colorectal cancer
Journal Articles

Abstract B020: Distinct spatiotemporal tumor-immune ecologies enable disease prediction in NSCLC patients

Free
Sandhya Prabhakaran, Chandler Gatenbee, Mark Robertson-Tessi, Amer A. Beg, Jhanelle Gray, Scott Antonia, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B020.
https://doi.org/10.1158/1538-7445.EVODYN22-B020
Published: 15 May 2022
View articletitled, Abstract B020: Distinct spatiotemporal tumor-immune ecologies enable disease prediction in NSCLC patients
Journal Articles

Abstract B009: Integrating mathematical modelling and wet-lab experiments to examine the scope for adaptive treatment scheduling of PARP inhibitors in ovarian cancer

Free
Maximilian Strobl, Mehdi Damaghi, Alexandra Martin, Samantha Byrne, Mark Robertson-Tessi, Robert Gatenby, Robert Wenham, Philip Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B009.
https://doi.org/10.1158/1538-7445.EVODYN22-B009
Published: 15 May 2022
View articletitled, Abstract B009: Integrating mathematical modelling and wet-lab experiments to examine the scope for adaptive treatment scheduling of PARP inhibitors in ovarian cancer
Journal Articles

Abstract B003: Evolutionary games in radiotherapy resistance: Exploiting an immunologic double bind in advanced prostate cancer

Free
Kimberly A. Luddy, Jeffery West, Mark Robertson-Tessi, Alexander R.A. Anderson, Taylor M. Bursell, Laure Marignol, Cliona O'Farrelly, Robert Gatenby
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B003.
https://doi.org/10.1158/1538-7445.EVODYN22-B003
Published: 15 May 2022
View articletitled, Abstract B003: Evolutionary games in radiotherapy resistance: Exploiting an immunologic double bind in advanced prostate cancer
Journal Articles

Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy

Available to Purchase
Maximilian A.R. Strobl, Jeffrey West, Yannick Viossat, Mehdi Damaghi, Mark Robertson-Tessi, Joel S. Brown, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2021) 81 (4): 1135–1147.
https://doi.org/10.1158/0008-5472.CAN-20-0806
Published: 15 February 2021
View articletitled, Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy
Open the PDF for Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy in another window
Includes: Supplementary data
Journal Articles

Searching for Goldilocks: How Evolution and Ecology Can Help Uncover More Effective Patient-Specific Chemotherapies

Available to Purchase
Derek S. Park, Kimberly A. Luddy, Mark Robertson-Tessi, Cliona O'Farrelly, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5147–5154.
https://doi.org/10.1158/0008-5472.CAN-19-3981
Published: 02 December 2020
View articletitled, Searching for Goldilocks: How Evolution and Ecology Can Help Uncover More Effective Patient-Specific Chemotherapies
Open the PDF for Searching for Goldilocks: How Evolution and Ecology Can Help Uncover More Effective Patient-Specific Chemotherapies in another window
Journal Articles

Towards Multidrug Adaptive Therapy

Available to Purchase
Jeffrey West, Li You, Jingsong Zhang, Robert A. Gatenby, Joel S. Brown, Paul K. Newton, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1578–1589.
https://doi.org/10.1158/0008-5472.CAN-19-2669
Published: 02 April 2020
View articletitled, Towards Multidrug Adaptive Therapy
Open the PDF for Towards Multidrug Adaptive Therapy in another window
Includes: Supplementary data
Journal Articles

The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right

Free
Derek S. Park, Mark Robertson-Tessi, Kimberly A. Luddy, Philip K. Maini, Michael B. Bonsall, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2019) 79 (20): 5302–5315.
https://doi.org/10.1158/0008-5472.CAN-18-3712
Published: 15 October 2019
View articletitled, The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right
Open the PDF for The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right in another window
Includes: Supplementary data
Journal Articles

Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies

Free
Jill A. Gallaher, Pedro M. Enriquez-Navas, Kimberly A. Luddy, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2127–2139.
https://doi.org/10.1158/0008-5472.CAN-17-2649
Published: 12 April 2018
View articletitled, Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies
Open the PDF for Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies in another window
Includes: Multimedia, Supplementary data
Journal Articles

Integrating Models to Quantify Environment-Mediated Drug Resistance

Free
Noemi Picco, Erik Sahai, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5409–5418.
https://doi.org/10.1158/0008-5472.CAN-17-0835
Published: 01 October 2017
View articletitled, Integrating Models to Quantify Environment-Mediated Drug Resistance
Open the PDF for Integrating Models to Quantify Environment-Mediated Drug Resistance in another window
Includes: Supplementary data
Journal Articles

Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution

Free
Arig Ibrahim-Hashim, Mark Robertson-Tessi, Pedro M. Enriquez-Navas, Mehdi Damaghi, Yoganand Balagurunathan, Jonathan W. Wojtkowiak, Shonagh Russell, Kam Yoonseok, Mark C. Lloyd, Marilyn M. Bui, Joel S. Brown, Alexander R.A. Anderson, Robert J. Gillies, Robert A. Gatenby
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (9): 2242–2254.
https://doi.org/10.1158/0008-5472.CAN-16-2844
Published: 30 April 2017
View articletitled, Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution
Open the PDF for Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution in another window
Includes: Supplementary data
Journal Articles

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories

Free
Benjamin Werner, Jacob G. Scott, Andrea Sottoriva, Alexander R.A. Anderson, Arne Traulsen, Philipp M. Altrock
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1705–1713.
https://doi.org/10.1158/0008-5472.CAN-15-2069
Published: 31 March 2016
View articletitled, The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories
Open the PDF for The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories in another window