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Alexander Kirschenbaum
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Journal Articles

Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

Kimberly McClinch, Rita A. Avelar, David Callejas, Sudeh Izadmehr, Danica Wiredja, Abbey Perl, Jaya Sangodkar, David B. Kastrinsky, Daniela Schlatzer, Maxwell Cooper, Janna Kiselar, Agnes Stachnik, Shen Yao, Divya Hoon, Daniel McQuaid, Nilesh Zaware, Yixuan Gong, David L. Brautigan, Stephen R. Plymate, Cynthia C.T. Sprenger, William K. Oh, Alice C. Levine, Alexander Kirschenbaum, John P. Sfakianos, Rosalie Sears, Analisa DiFeo, Yiannis Ioannou, Michael Ohlmeyer, Goutham Narla, Matthew D. Galsky
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2065–2080.
https://doi.org/10.1158/0008-5472.CAN-17-0123
Published: 12 April 2018
View article titled, Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Abstract A57: Functional synergy between the KLF6-SV1 and c-MYC oncogenes in driving prostate cancer metastasis in a novel mouse model of the disease

Sudeh Izadmehr, Christine H. Lee, Heriberto Fernandez, Raheleh Hatami, Alexander Kirschenbaum, Alice C. Levine, AnaLisa Difeo, Goutham Narla
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): A57.
https://doi.org/10.1158/1538-7445.PRCA2012-A57
Published: 09 May 2013
View article titled, Abstract A57: Functional synergy between the KLF6-SV1 and c-MYC oncogenes in driving prostate cancer metastasis in a novel mouse model of the disease
Journal Articles

Abstract 5314: An oncogenic splice variant of the KLF6 tumor suppressor gene is associated with poor survival and is a potent driver of breast cancer metastasis

Raheleh Hatami, Jessica Ohlseen, Sudeh Izadmehr, Anieta M. Sieuwerts, Luena Papa, Alexander Kirschenbaum, Alice Levine, Doris Germain, John A. Foekens, Analisa DiFeo, Goutham Narla
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5314.
https://doi.org/10.1158/1538-7445.AM2012-5314
Published: 15 April 2012
View article titled, Abstract 5314: An oncogenic splice variant of the KLF6 tumor suppressor gene is associated with poor survival and is a potent driver of breast cancer metastasis
Journal Articles

Abstract LB-375: Development of new compounds specifically targeting prostate cancer bone metastases

Alice C. Levine, Barrie Weinstein, XinHua Liu, Steven Regan, Vasek Janout, Alexander Kirschenbaum
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-375.
https://doi.org/10.1158/1538-7445.AM10-LB-375
Published: 15 April 2010
View article titled, Abstract LB-375: Development of new compounds specifically targeting prostate cancer bone metastases
Journal Articles

Abstract #55: Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells

Xin Hua Liu, SuDao Xiong, Li Hui Yin, Alexander Kirschenbaum, Shen Yao, Goutham Narla, Analisa DiFeo, Kang Yu, Jian Bo Wu, Yong Yuan, Shuk-Mei Ho, Ying Wai Lam, Alice Levine
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 55.
Published: 01 May 2009
View article titled, Abstract #55: Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells
Journal Articles

Androgen-Induced Wnt Signaling in Preosteoblasts Promotes the Growth of MDA-PCa-2b Human Prostate Cancer Cells

Xin-Hua Liu, Alexander Kirschenbaum, Shen Yao, Guizhong Liu, Stuart A. Aaronson, Alice C. Levine
Journal: Cancer Research
Cancer Res (2007) 67 (12): 5747–5753.
https://doi.org/10.1158/0008-5472.CAN-07-0478
Published: 15 June 2007
View article titled, Androgen-Induced Wnt Signaling in Preosteoblasts Promotes the Growth of MDA-PCa-2b Human Prostate Cancer Cells
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Journal Articles

Targeted Inhibition of the KLF6 Splice Variant, KLF6 SV1, Suppresses Prostate Cancer Cell Growth and Spread

Goutham Narla, Analisa DiFeo, Shen Yao, Asoka Banno, Eldad Hod, Helen L. Reeves, Rui F. Qiao, Olga Camacho-Vanegas, Alice Levine, Alexander Kirschenbaum, Andrew M. Chan, Scott L. Friedman, John A. Martignetti
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5761–5768.
https://doi.org/10.1158/0008-5472.CAN-05-0217
Published: 01 July 2005
View article titled, Targeted Inhibition of the KLF6 Splice Variant, KLF6 SV1, Suppresses Prostate Cancer Cell Growth and Spread
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Journal Articles

Zone specific gene expression and regulation in prostatic basal cells

Xin-Hua Liu, Alexander Kirschenbaum, Shen Yao, Alice C. Levine
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1286.
Published: 01 May 2005
View article titled, Zone specific gene expression and regulation in prostatic basal cells
Journal Articles

Cyclooxygenase-2 suppresses hypoxia-induced p53 activation via promotion of MDM2 phosphorylation and inhibition of p53 nuclear localization in a prostate cancer cell line

Xin-Hua Liu, Alexander Kirschenbaum, Kang Yu, Shen Yao, James F. Holland, Alice C. Levine
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 618.
Published: 01 April 2004
View article titled, Cyclooxygenase-2 suppresses hypoxia-induced p53 activation via promotion of MDM2 phosphorylation and inhibition of p53 nuclear localization in a prostate cancer cell line
Journal Articles

NS398, a Selective Cyclooxygenase-2 Inhibitor, Induces Apoptosis and Down-Regulates bcl-2 Expression in LNCaP Cells

Xin-Hua Liu, Shen Yao, Alexander Kirschenbaum, Alice C. Levine
Journal: Cancer Research
Cancer Res (1998) 58 (19): 4245–4249.
Published: 01 October 1998
View article titled, NS398, a Selective Cyclooxygenase-2 Inhibitor, Induces Apoptosis and Down-Regulates bcl-2 Expression in LNCaP Cells
Open the PDF for NS398, a Selective Cyclooxygenase-2 Inhibitor, Induces Apoptosis and Down-Regulates bcl-2 Expression in LNCaP Cells in another window