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Journal Articles

Abstract 3814: Molecular background conditioning by temozolomide in neuroendocrine tumors

Elena Trevisani, Anna Reni, Irene Torresan, Alice Rossi, Michele Borghesani, Silvia Nicolini, Claudio Luchini, Luca Landoni, Davide Melisi, Aldo Scarpa, Michele Milella, Andrea Mafficini, Sara Cingarlini
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3814.
https://doi.org/10.1158/1538-7445.AM2024-3814
Published: 22 March 2024
View article titled, Abstract 3814: Molecular background conditioning by temozolomide in neuroendocrine tumors
Journal Articles

Abstract 4892: Pentraxin 3: A stromal derived diagnostic biomarker for pancreatic ductal adenocarcinoma

Michelle R. Goulart, Jennifer Watt, Imran Siddique, Rita Lawor, Thomas Dowe, Satyajit Bhattacharya, Tatjana Crnogorac-Jurcevic, Paola Allavena, Aldo Scarpa, Hemant M. Kocher
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4892.
https://doi.org/10.1158/1538-7445.AM2019-4892
Published: 01 July 2019
View article titled, Abstract 4892: Pentraxin 3: A stromal derived diagnostic biomarker for pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3501: Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling

Carmine Carbone, Geny Piro, Raffaela Santoro, Francesca Simionato, Valeria Merz, Camilla Zecchetto, Aldo Scarpa, Giampaolo Tortora, Davide Melisi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3501.
https://doi.org/10.1158/1538-7445.AM2018-3501
Published: 01 July 2018
View article titled, Abstract 3501: Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling
Journal Articles

Abstract 1135: DRD2 is critical for pancreatic cancer and promises pharmacological therapy by already established antagonists

Pouria Jandaghi, Hamed S. Najafabadi, Andrea Bauer, Andreas I. Papadakis, Matteo Fassan, Anita Hall, Anie Monast, Maryam Safisamghabadi, Magnus von Knebel Doeberitz, John P. Neoptolemos, Eithne Costello, William Greenhalf, Aldo Scarpa, Bence Sipos, Daniel Auld, Mark Lathrop, Morag Park, Markus W. Büchler, Oliver Strobel, Thilo Hackert, Nathalia Giese, George Zogopoulos, Veena Sangwan, Sidong Huang, Jörg D. Hoheisel, Yaser Riazalhosseini
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1135.
https://doi.org/10.1158/1538-7445.AM2017-1135
Published: 01 July 2017
View article titled, Abstract 1135: DRD2 is critical for pancreatic cancer and promises pharmacological therapy by already established antagonists
Journal Articles

Abstract 3411: Rare BRCA2 K3326X increases susceptibility to sporadic pancreatic ductal adenocarcinoma: a PANDoRA study

Ofure M. Obazee, Gabriele Capurso, Angelo Andriulli, Pavel Soucek, Ewa Małecka- Panas, Juozas Kupcinskas, Rudolf Kaaks, Maria Gazouli, Thilo Hackert, Aldo Scarpa, Giulia M. Cavestro, Claudio Pasquali, Hermann Brenner, Daniele Campa, Raffaele Pezzilli, Andrea Mambrini, Beatrice Mohelnikova- Duchonova, Ugo Boggi, Jakob Izbicki, Pavel Vodicka, Elzbieta Iskierka-Jazdzewska, Federico Canzian
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3411.
https://doi.org/10.1158/1538-7445.AM2017-3411
Published: 01 July 2017
View article titled, Abstract 3411: Rare BRCA2 K3326X increases susceptibility to sporadic pancreatic ductal adenocarcinoma: a PANDoRA study
Journal Articles

Abstract 5694: Multi institutional evaluation of a new NGS assay for mutation detection from cfDNA in lung cancer

Jose L. Costa, Robbert Weren, Anna Maria Rachiglio, Andrea Mafficini, Henriette Kurth, Anne Reiman, Audrey Didelot, Alexander Boag, Claudia Vollbrecht, Kazuto Nishino, Harriet E. Feilotter, Pierre Laurent-Puig, Orla Sheils, Aldo Scarpa, Marjolijn Ligtenberg, Ian A. Cree, Michael Hummel, Jose Carlos Machado, Nicola Normanno
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5694.
https://doi.org/10.1158/1538-7445.AM2017-5694
Published: 01 July 2017
View article titled, Abstract 5694: Multi institutional evaluation of a new NGS assay for mutation detection from cfDNA in lung cancer
Journal Articles

Abstract 1069: MiR-21 may serve as a predictive biomarker of response in the assessment of efficacy of HSP-90 inhibition in gastrointestinal (GI) cancers

Andrea Lampis, Luciano Cascione, Rosemary Burke, Paul Clarke, Michele Simbolo, Aldo Scarpa, Else Bosma, Sijia Yu, Rebecca Cole, Mark Stubbs, Swee Sharp, Rob Van Montfort, Jens C. Hahne, Matteo Fassan, Paul Workman, Nicola Valeri, Chiara Braconi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1069.
https://doi.org/10.1158/1538-7445.AM2016-1069
Published: 15 July 2016
View article titled, Abstract 1069: MiR-21 may serve as a predictive biomarker of response in the assessment of efficacy of HSP-90 inhibition in gastrointestinal (GI) cancers
Journal Articles

Abstract 3265: Homeobox B9 (HOXB9) sustains anti-VEGF treatment resistance in gastrointestinal tumors

Carmine Carbone, Geny Piro, Francesca Simionato, Fotios Loupakis, Chiara Cremolini, Gabriella Fontanini, Federica Di Nicolantonio, Elisa Moratti, Francesca Ligorio, Marco Zanotto, Raffaela Santoro, Maria Mihaela Mina, Aldo Scarpa, Alberto Bardelli, Giampaolo Tortora, Davide Melisi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3265.
https://doi.org/10.1158/1538-7445.AM2016-3265
Published: 15 July 2016
View article titled, Abstract 3265: Homeobox B9 (HOXB9) sustains anti-VEGF treatment resistance in gastrointestinal tumors
Journal Articles

Abstract 3617: Digital sorting rescues low-cellularity tumor FFPE samples for genome-wide copy-number profiling

Claudio Forcato, Julie Lalibertè, Chiara Bolognesi, Ivana Cataldo, Genny Buson, Chiara Mangano, Cinzia Cantù, Francesca Fontana, Paola Tononi, Gianni Medoro, Tim Harkins, Rita T. Lawlor, Aldo Scarpa, Nicolò Manaresi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3617.
https://doi.org/10.1158/1538-7445.AM2016-3617
Published: 15 July 2016
View article titled, Abstract 3617: Digital sorting rescues low-cellularity tumor FFPE samples for genome-wide copy-number profiling
Journal Articles

Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression

Sandeep K. Botla, Soniya Savant, Pouria Jandaghi, Andrea S. Bauer, Oliver Mücke, Evgeny A. Moskalev, John P. Neoptolemos, Eithne Costello, William Greenhalf, Aldo Scarpa, Matthias M. Gaida, Markus W. Büchler, Oliver Strobel, Thilo Hackert, Nathalia A. Giese, Hellmut G. Augustin, Jörg D. Hoheisel
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (14): 4149–4159.
https://doi.org/10.1158/0008-5472.CAN-15-0390
Published: 14 July 2016
View article titled, Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression
Open the PDF for Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 1109: In vivo loss of function screening reveals carbonic anhydrase IX (CAIX) as a key modulator of tumor initiating potential in primary pancreatic tumors

Nabendu Pore, Sanjoo Jalla, Brandon Higgs, Roger Liu, David A. Tice, Robert Hollingsworrth, Emil Michelotti, Claudio Sorio, Aldo Scarpa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1109.
https://doi.org/10.1158/1538-7445.AM2015-1109
Published: 01 August 2015
View article titled, Abstract 1109: <em>In vivo</em> loss of function screening reveals carbonic anhydrase IX (CAIX) as a key modulator of tumor initiating potential in primary pancreatic tumors
Journal Articles

Abstract 3605: Combined inhibition of IL-1, CXCR1/2, and TGFβ signaling pathways modulates in vivo acquired resistance to anti-VEGF treatment

Carmine Carbone, Anna Tamburrino, Geny Piro, Marco Zanotto, Maria Mihaela Mina, Silvia Zanini, Federico Boschi, Aldo Scarpa, Giampaolo Tortora, Davide Melisi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3605.
https://doi.org/10.1158/1538-7445.AM2015-3605
Published: 01 August 2015
View article titled, Abstract 3605: Combined inhibition of IL-1, CXCR1/2, and TGFβ signaling pathways modulates in vivo acquired resistance to anti-VEGF treatment
Journal Articles

Abstract 4891: Comprehensive genetic profiling of chromosomal translocations in lung cancer tumors: development and validation of a next-generation sequencing panel in an international multicenter study

Pierre Laurent - Puig, Jose Louis Costa, Orla Sheils, Bastiaan Tops, Andrea Mafficini, Delphine Le Corre, Henriette Kurth, Anna Maria Rachiglio, Helene Blons, Eliana Amato, Christoph Noppen, Renato Franco, Anne Reiman, Roy Bastien, Noah Welker, Jose Carlos Machado, Ian Cree, Harriet Feilotter, Marjolijn Ligtenberg, Aldo Scarpa, Nicola Normanno, Kazuto Nishio, Cecily Vaughn
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4891.
https://doi.org/10.1158/1538-7445.AM2015-4891
Published: 01 August 2015
View article titled, Abstract 4891: Comprehensive genetic profiling of chromosomal translocations in lung cancer tumors: development and validation of a next-generation sequencing panel in an international multicenter study
Journal Articles

Abstract A60: The hMENA Splicing Program: An important regulator of TGFβ1-driven EMT and invasiveness in pancreatic cancer

Roberta Melchionna, Pierluigi Iapicca, Francesca Di Modugno, Paola Trono, Novella Gualtieri, Maria Grazia Diodoro, Marcella Mottolese, Gian Luca Grazi, Matteo Fassan, Aldo Scarpa, Mina J. Bissell, Paola Nisticò
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A60.
https://doi.org/10.1158/1538-7445.PANCA2014-A60
Published: 30 June 2015
View article titled, Abstract A60: The hMENA Splicing Program: An important regulator of TGFβ1-driven EMT and invasiveness in pancreatic cancer
Journal Articles

Abstract B12: Circulating stroma-related molecules as potential biomarkers for pancreatic ductal adenocarcinoma

Dorina Belotti, Andrea Resovi, Giulia Taraboletti, Rita T. Lawlor, Aldo Scarpa, Raffaella Giavazzi
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B12.
https://doi.org/10.1158/1538-7445.PANCA2014-B12
Published: 30 June 2015
View article titled, Abstract B12: Circulating stroma-related molecules as potential biomarkers for pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3575: The OncoNetwork Consortium: A global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel

Susan M. Magdaleno, Angie Cheng, Rosella Petraroli, Orla Sheils, Bastiaan Tops, Delphine L. Corre, Henriette Kurth, Helene Blons, Eliana Amato, Andrea Mafficini, Anna Maria Rachiglio, Anne Reimann, Christoph Noppen, Chrysanthi Ainali, Jin Katayama, Renato Franco, Harriet Feilotter, Jeoffrey Schageman, Ian Cree, Andrew Felton, Jose Luis Costa, Alain Rico, Aldo Scarpa, Jose Carlos Machado, Kazuto Nishio, Nicola Normanno, Marjolijn Ligtenberg, Cecily P. Vaughn, Ludovic Lacroix, Pierre Laurent-Puig
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3575.
https://doi.org/10.1158/1538-7445.AM2014-3575
Published: 01 October 2014
View article titled, Abstract 3575: The OncoNetwork Consortium: A global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel
Journal Articles

Abstract B42: Toward targeting integrin αvβ6 for the therapy of pancreatic cancer.

Sabari Vallath, Emaunela Gadaletta, Claude Chelala, Aldo Scarpa, Ian R. Hart, Hemant M. Kocher, John F. Marshall
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B42.
https://doi.org/10.1158/1538-7445.PANCA2012-B42
Published: 03 April 2014
View article titled, Abstract B42: Toward targeting integrin αvβ6 for the therapy of pancreatic cancer.
Journal Articles

Abstract 36: The OncoNetwork Consortium: A European Collaborative Research study on the development of an Ion AmpliSeq gene panel targeting hot spots in colon and lung cancers.

Nicola Normanno, Rosella Petraroli, Alain Rico, Henriette Kurth, Bastiaan Tops, Eliana Amato, Andrea Mafficini, Delphine Le Corre, Anna Maria Rachiglio, Anne Reiman, Orla Sheils, Christoph Noppen, Nora Rieber, Jonathan Mangion, Chrysanthi Ainali, Ludovic Lacroix, Ian Cree, Marjolijn Ligtenberg, Andy Felton, Aldo Scarpa, Pierre Laurent Puig
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 36.
https://doi.org/10.1158/1538-7445.AM2013-36
Published: 15 April 2013
View article titled, Abstract 36: The OncoNetwork Consortium: A European Collaborative Research study on the development of an Ion AmpliSeq gene panel targeting hot spots in colon and lung cancers.
Journal Articles

Abstract #195: Characteritazion of Panc-1 spheres system model in vitro and in vivo

Margherita Gaviraghi, Mario Dandrea, Rossana Ritelli, Patrizia Tunici, Silvia Valensin, Aldo Scarpa, Annette Bakker
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 195.
Published: 01 May 2009
View article titled, Abstract #195: Characteritazion of Panc-1 spheres system model <em>in vitro</em> and <em>in vivo</em>
Journal Articles

Characterization of Panc-1 and Cfpac pancreatic cancer stem cells.

Margherita Gaviraghi, Mario Dandrea, Patrizia Tunici, Aldo Scarpa, Annette Bakker
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4587.
Published: 01 May 2008
View article titled, Characterization of Panc-1 and Cfpac pancreatic cancer stem cells.