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Albrecht Seidel
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Journal Articles

Determination of alkylated polycyclic aromatic hydrocarbons in environmental matrices

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Albrecht Seidel, Heinz Frank, Andrea John, Hansruedi Glatt
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5018.
Published: 01 May 2007
View article titled, Determination of alkylated polycyclic aromatic hydrocarbons in environmental matrices
Journal Articles

Differential effects of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons on Mdm2 and p53 phosphorylation

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Ase Mattsson, Maria Malmlof, Albrecht Seidel, Ulla Stenius, Bengt Jernstrom
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4262.
Published: 01 May 2007
View article titled, Differential effects of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons on Mdm2 and p53 phosphorylation
Journal Articles

DNA adducts derived from tumorigenic benzo[a]pyrene and dibenzo[a,l]pyrene and activation of Mdm2 and p53

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Gerd Pääjärvi, Ulla Stenius, Albrecht Seidel, Bengt Jernström
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 88.
Published: 15 April 2006
View article titled, DNA adducts derived from tumorigenic benzo[a]pyrene and dibenzo[a,l]pyrene and activation of Mdm2 and p53
Journal Articles

Exposure of human A549 and HepG2 cells to tumorigenic diol epoxides from benzo[a]pyrene and dibenzo[a,l]pyrene and effects on Mdm2 and p53

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Gerd Pääjärvi, Ulla Stenius, Albrecht Seidel, Bengt Jernström
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 715.
Published: 01 May 2005
View article titled, Exposure of human A549 and HepG2 cells to tumorigenic diol epoxides from benzo[a]pyrene and dibenzo[a,l]pyrene and effects on Mdm2 and p53
Journal Articles

Unrepaired Fjord Region Polycyclic Aromatic Hydrocarbon-DNA Adducts in ras Codon 61 Mutational Hot Spots

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Tonko Buterin, Martin T. Hess, Natalia Luneva, Nicholas E. Geacintov, Shantu Amin, Heiko Kroth, Albrecht Seidel, Hanspeter Naegeli
Journal: Cancer Research
Cancer Res (2000) 60 (7): 1849–1856.
Published: 01 April 2000
View article titled, Unrepaired Fjord Region Polycyclic Aromatic Hydrocarbon-DNA Adducts in ras Codon 61 Mutational Hot Spots
Open the PDF for Unrepaired Fjord Region Polycyclic Aromatic Hydrocarbon-DNA Adducts in ras Codon 61 Mutational Hot Spots in another window
Journal Articles

The K-Region trans-8,9-Diol Does Not Significantly Contribute as an Intermediate in the Metabolic Activation of Dibenzo[a,l]pyrene to DNA-binding Metabolites by Human Cytochrome P450 1A1 or 1B1

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Andreas Luch, Shirley Kishiyama, Albrecht Seidel, Johannes Doehmer, Helmut Greim, William M. Baird
Journal: Cancer Research
Cancer Res (1999) 59 (18): 4603–4609.
Published: 15 September 1999
View article titled, The K-Region trans-8,9-Diol Does Not Significantly Contribute as an Intermediate in the Metabolic Activation of Dibenzo[a,l]pyrene to DNA-binding Metabolites by Human Cytochrome P450 1A1 or 1B1
Open the PDF for The K-Region trans-8,9-Diol Does Not Significantly Contribute as an Intermediate in the Metabolic Activation of Dibenzo[a,l]pyrene to DNA-binding Metabolites by Human Cytochrome P450 1A1 or 1B1 in another window
Journal Articles

Comparison of Cytochrome P450- and Peroxidase-dependent Metabolic Activation of the Potent Carcinogen Dibenzo[a,l]pyrene in Human Cell Lines: Formation of Stable DNA Adducts and Absence of a Detectable Increase in Apurinic Sites

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Victor J. Melendez-Colon, Andreas Luch, Albrecht Seidel, William M. Baird
Journal: Cancer Research
Cancer Res (1999) 59 (7): 1412–1416.
Published: 01 April 1999
View article titled, Comparison of Cytochrome P450- and Peroxidase-dependent Metabolic Activation of the Potent Carcinogen Dibenzo[a,l]pyrene in Human Cell Lines: Formation of Stable DNA Adducts and Absence of a Detectable Increase in Apurinic Sites
Open the PDF for Comparison of Cytochrome P450- and Peroxidase-dependent Metabolic Activation of the Potent Carcinogen Dibenzo[a,l]pyrene in Human Cell Lines: Formation of Stable DNA Adducts and Absence of a Detectable Increase in Apurinic Sites in another window
Journal Articles

The Potent Carcinogen Dibenzo[a,l]pyrene Is Metabolically Activated to Fjord-Region 11,12-Diol 13,14-Epoxides in Human Mammary Carcinoma MCF-7 Cell Cultures

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Sherry L. Ralston, Hudson H. S. Lau, Albrecht Seidel, Andreas Luch, Karl L. Platt, William M. Baird
Journal: Cancer Research
Cancer Res (1994) 54 (4): 887–890.
Published: 01 February 1994
View article titled, The Potent Carcinogen Dibenzo[a,l]pyrene Is Metabolically Activated to Fjord-Region 11,12-Diol 13,14-Epoxides in Human Mammary Carcinoma MCF-7 Cell Cultures
Open the PDF for The Potent Carcinogen Dibenzo[a,l]pyrene Is Metabolically Activated to Fjord-Region 11,12-Diol 13,14-Epoxides in Human Mammary Carcinoma MCF-7 Cell Cultures in another window
Journal Articles

Fjord- and Bay-Region Diol-Epoxides Investigated for Stability, SOS Induction in Escherichia coli, and Mutagenicity in Salmonella typhimurium and Mammalian Cells

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Hansruedi Glatt, Andrea Piée, Karin Pauly, Thomas Steinbrecher, Rainer Schrode, Franz Oesch, Albrecht Seidel
Journal: Cancer Research
Cancer Res (1991) 51 (6): 1659–1667.
Published: 01 March 1991
View article titled, Fjord- and Bay-Region Diol-Epoxides Investigated for Stability, SOS Induction in Escherichia coli, and Mutagenicity in Salmonella typhimurium and Mammalian Cells
Open the PDF for Fjord- and Bay-Region Diol-Epoxides Investigated for Stability, SOS Induction in Escherichia coli, and Mutagenicity in Salmonella typhimurium and Mammalian Cells in another window
Journal Articles

Mutagenic and Cell-transforming Activities of Triol-Epoxides as Compared to Other Chrysene Metabolites

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Hansruedi Glatt, Albrecht Seidel, Werner Bochnitschek, Hildegard Marquardt, Hans Marquardt, Ruth M. Hodgson, Philip L. Grover, Franz Oesch
Journal: Cancer Research
Cancer Res (1986) 46 (9): 4556–4565.
Published: 01 September 1986
View article titled, Mutagenic and Cell-transforming Activities of Triol-Epoxides as Compared to Other Chrysene Metabolites
Open the PDF for Mutagenic and Cell-transforming Activities of Triol-Epoxides as Compared to Other Chrysene Metabolites in another window